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The map label for this gene is hfq

Identifier: 34498988

GI number: 34498988

Start: 3841590

End: 3841850

Strand: Reverse

Name: hfq

Synonym: CV_3533

Alternate gene names: 34498988

Gene position: 3841850-3841590 (Counterclockwise)

Preceding gene: 34498989

Following gene: 34498987

Centisome position: 80.86

GC content: 54.02

Gene sequence:

>261_bases
ATGAGCTCTAAAGGGCAAATGTTACAAGACCCCTTCCTGAATATCCTGCGCAAGGAACACGTGCCGGTTTCCATTTATCT
GGTTAACGGCATCAAGCTGCAAGGTCAGGTTGAATCTTTTGACCAATACGTCGTTCTGCTGAAGAACACGGTCACCCAGA
TGGTCTACAAGCACGCCATCTCCACCGTGGTTCCGGCCCGCCCGGTCAATATCCCGCACGAGCACCCGGCGCAAAAGCAG
GAACAGGCGCAGGACGCCTAA

Upstream 100 bases:

>100_bases
GCAAGAAATAGTACGGCGGAATGTTTTCTGCTAAAAATAAGCAGGCCGCCGCGCTGTTTGCTGGACTTAATACAACAATC
AACGATTCGGAGAAAAACGA

Downstream 100 bases:

>100_bases
ACCGTCCTCGCTTCGCCGATCGGGCCGATTGGCCGCATCTCAGGATGCGGCCTTTCGGCCTTTGTCATTTATCGCCGTAC
TCACGAATGGTTAGCAAACA

Product: host factor-I protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MSSKGQMLQDPFLNILRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLKNTVTQMVYKHAISTVVPARPVNIPHEHPAQKQ
EQAQDA

Sequences:

>Translated_86_residues
MSSKGQMLQDPFLNILRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLKNTVTQMVYKHAISTVVPARPVNIPHEHPAQKQ
EQAQDA
>Mature_85_residues
SSKGQMLQDPFLNILRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLKNTVTQMVYKHAISTVVPARPVNIPHEHPAQKQE
QAQDA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=68, Percent_Identity=83.8235294117647, Blast_Score=125, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_CHRVO (Q7NS93)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903203.1
- ProteinModelPortal:   Q7NS93
- SMR:   Q7NS93
- GeneID:   2547574
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3533
- NMPDR:   fig|243365.1.peg.3533
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- PhylomeDB:   Q7NS93
- ProtClustDB:   CLSK2485623
- BioCyc:   CVIO243365:CV_3533-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9721; Mature: 9590

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKGQMLQDPFLNILRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLKNTVTQMVYKHAI
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
STVVPARPVNIPHEHPAQKQEQAQDA
HHHCCCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
SSKGQMLQDPFLNILRKEHVPVSIYLVNGIKLQGQVESFDQYVVLLKNTVTQMVYKHAI
CCCCCCHHHHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
STVVPARPVNIPHEHPAQKQEQAQDA
HHHCCCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782