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The map label for this gene is engA

Identifier: 34498989

GI number: 34498989

Start: 3841940

End: 3843349

Strand: Reverse

Name: engA

Synonym: CV_3534

Alternate gene names: 34498989

Gene position: 3843349-3841940 (Counterclockwise)

Preceding gene: 34498990

Following gene: 34498988

Centisome position: 80.89

GC content: 63.55

Gene sequence:

>1410_bases
ATGAAACCTACCGTAGCGCTGGTCGGCCGCCCCAATGTGGGCAAGTCGACCCTTTTCAATCGGCTGACCCGCAGCCGCGA
CGCCTTGGTCGCCGACCAGCCTGGTCTGACGCGTGACCGCCACTACGGCCAAGGCCGCGTTGGCGAGAAACCGTACCTGG
TGGTCGACACCGGCGGCTTCGAGCCGGTGGTGGACGAAGGCATCCTGTTCGAGATGGCCAAGCAGACGCTGCAGGCCGTC
GACGAAGCGGATGCCGTGGTCTTCCTGGTGGATGGCCGCGCCGGCCTGACGCCGCAGGACAAGATCATCGCCAACCGCCT
GCGCCAGCTGGACCGCCCGGTGTTCCTGGCCGTCAACAAGGCCGAGGGCATGAAGCACGCGATCGCCGGCGCCGAGTTCC
ACGAACTGGCGCTGGGCGAGCCGCTGGTGATCTCCGCCGCCCACGGCGACGGCGTGCGCGAGCTGATGGAGCTGGTGCTG
GAAGGCTTCCCCGACGAAGTCGAGGAAGAGGACAGCCGCCATCCGAAGTTCGCGGTGATCGGCCGTCCCAACGTTGGCAA
GTCCACGCTGGTCAACGCCATCCTCGGCGAAGAGCGGGTGATCGCCTTCGATCAGGCCGGAACCACGCGCGACAGCATCT
ATATTGATTTTGAGCGCGAAGGCCATACCTATACCATCATCGACACCGCCGGCGTGCGCCGCCGCGCCAAGGTCAACGAG
ATGCTGGAGAAATTCTCCGTCATCAAGACCATGAAGGCGATCGAGGACGCCAACGTCGCGGTGCTGGTGCTGGACGCGCA
GCTGGACATCTCCGAGCAGGACGCCACCATCGCCGGTTTCGCGCTGGAAGCGGGCCGCGCCTTGGTGGTGGCGGTCAACA
AGTGGGACAATCTCGACGGCGAGCAGAAGGAAAACGTGCGCCGCGAGATCGCCCGCAAGCTGAACTTCCTGGATTTCGCA
AAGTTTCATTACATCTCGGCCATCGAGGGCCGCGGTGTGGCAGACTTGTTCAAGTCCATCGACGAAGCCTACCGCGCGGC
GATGAGCAAGCTGGCGACGCCGAAGCTCACCCGCGTGCTGCAGGTGGCGCTGGAGCGCCAGCAGCCGCCGCGCTCGGGCC
TGATCCGTCCCAAGATGCGCTATGCGCACCAGGGCGGCCAGAACCCGCCGGTGATCGTCGTGCACGGCAATGCGCTGGAC
AGCATTCCGGCCAGCTATACCCGCTATCTGGAACATACTTTCCGTAAAGTGTTCAAATTGCAGGGTACGCCGCTGAGAGT
GCAGTACAAGTCGTCGGAAAACCCGTTCGACAACGACGAAAAGGACAAGCCGCGGGCCAAGCCCAAGCCGATGTCCAAGA
TGCGGGGCAGGGAAAAGGAAGTTCGCTACGGCAAAAACAGCAAGAAATAG

Upstream 100 bases:

>100_bases
ACCGGACCGGTCAATCAACCGGTGTCGCTCGGCTCCTCCGCCCTGGTACAGGGACGCGACGGCCGCCTGGCGATGCTGAA
TCTGGGATAAGCAGTTTTAG

Downstream 100 bases:

>100_bases
TACGGCGGAATGTTTTCTGCTAAAAATAAGCAGGCCGCCGCGCTGTTTGCTGGACTTAATACAACAATCAACGATTCGGA
GAAAAACGAATGAGCTCTAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKPTVALVGRPNVGKSTLFNRLTRSRDALVADQPGLTRDRHYGQGRVGEKPYLVVDTGGFEPVVDEGILFEMAKQTLQAV
DEADAVVFLVDGRAGLTPQDKIIANRLRQLDRPVFLAVNKAEGMKHAIAGAEFHELALGEPLVISAAHGDGVRELMELVL
EGFPDEVEEEDSRHPKFAVIGRPNVGKSTLVNAILGEERVIAFDQAGTTRDSIYIDFEREGHTYTIIDTAGVRRRAKVNE
MLEKFSVIKTMKAIEDANVAVLVLDAQLDISEQDATIAGFALEAGRALVVAVNKWDNLDGEQKENVRREIARKLNFLDFA
KFHYISAIEGRGVADLFKSIDEAYRAAMSKLATPKLTRVLQVALERQQPPRSGLIRPKMRYAHQGGQNPPVIVVHGNALD
SIPASYTRYLEHTFRKVFKLQGTPLRVQYKSSENPFDNDEKDKPRAKPKPMSKMRGREKEVRYGKNSKK

Sequences:

>Translated_469_residues
MKPTVALVGRPNVGKSTLFNRLTRSRDALVADQPGLTRDRHYGQGRVGEKPYLVVDTGGFEPVVDEGILFEMAKQTLQAV
DEADAVVFLVDGRAGLTPQDKIIANRLRQLDRPVFLAVNKAEGMKHAIAGAEFHELALGEPLVISAAHGDGVRELMELVL
EGFPDEVEEEDSRHPKFAVIGRPNVGKSTLVNAILGEERVIAFDQAGTTRDSIYIDFEREGHTYTIIDTAGVRRRAKVNE
MLEKFSVIKTMKAIEDANVAVLVLDAQLDISEQDATIAGFALEAGRALVVAVNKWDNLDGEQKENVRREIARKLNFLDFA
KFHYISAIEGRGVADLFKSIDEAYRAAMSKLATPKLTRVLQVALERQQPPRSGLIRPKMRYAHQGGQNPPVIVVHGNALD
SIPASYTRYLEHTFRKVFKLQGTPLRVQYKSSENPFDNDEKDKPRAKPKPMSKMRGREKEVRYGKNSKK
>Mature_469_residues
MKPTVALVGRPNVGKSTLFNRLTRSRDALVADQPGLTRDRHYGQGRVGEKPYLVVDTGGFEPVVDEGILFEMAKQTLQAV
DEADAVVFLVDGRAGLTPQDKIIANRLRQLDRPVFLAVNKAEGMKHAIAGAEFHELALGEPLVISAAHGDGVRELMELVL
EGFPDEVEEEDSRHPKFAVIGRPNVGKSTLVNAILGEERVIAFDQAGTTRDSIYIDFEREGHTYTIIDTAGVRRRAKVNE
MLEKFSVIKTMKAIEDANVAVLVLDAQLDISEQDATIAGFALEAGRALVVAVNKWDNLDGEQKENVRREIARKLNFLDFA
KFHYISAIEGRGVADLFKSIDEAYRAAMSKLATPKLTRVLQVALERQQPPRSGLIRPKMRYAHQGGQNPPVIVVHGNALD
SIPASYTRYLEHTFRKVFKLQGTPLRVQYKSSENPFDNDEKDKPRAKPKPMSKMRGREKEVRYGKNSKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=497, Percent_Identity=48.4909456740443, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1788919, Length=121, Percent_Identity=35.5371900826446, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI2367268, Length=90, Percent_Identity=37.7777777777778, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CHRVO (Q7NS92)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903204.1
- ProteinModelPortal:   Q7NS92
- SMR:   Q7NS92
- GeneID:   2547575
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3534
- NMPDR:   fig|243365.1.peg.3534
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q7NS92
- ProtClustDB:   PRK00093
- BioCyc:   CVIO243365:CV_3534-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 52245; Mature: 52245

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTVALVGRPNVGKSTLFNRLTRSRDALVADQPGLTRDRHYGQGRVGEKPYLVVDTGGF
CCCCEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVVDEGILFEMAKQTLQAVDEADAVVFLVDGRAGLTPQDKIIANRLRQLDRPVFLAVNK
CHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEC
AEGMKHAIAGAEFHELALGEPLVISAAHGDGVRELMELVLEGFPDEVEEEDSRHPKFAVI
CCCHHHHHCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEE
GRPNVGKSTLVNAILGEERVIAFDQAGTTRDSIYIDFEREGHTYTIIDTAGVRRRAKVNE
ECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHH
MLEKFSVIKTMKAIEDANVAVLVLDAQLDISEQDATIAGFALEAGRALVVAVNKWDNLDG
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCC
EQKENVRREIARKLNFLDFAKFHYISAIEGRGVADLFKSIDEAYRAAMSKLATPKLTRVL
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QVALERQQPPRSGLIRPKMRYAHQGGQNPPVIVVHGNALDSIPASYTRYLEHTFRKVFKL
HHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
QGTPLRVQYKSSENPFDNDEKDKPRAKPKPMSKMRGREKEVRYGKNSKK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCCCC
>Mature Secondary Structure
MKPTVALVGRPNVGKSTLFNRLTRSRDALVADQPGLTRDRHYGQGRVGEKPYLVVDTGGF
CCCCEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVVDEGILFEMAKQTLQAVDEADAVVFLVDGRAGLTPQDKIIANRLRQLDRPVFLAVNK
CHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEC
AEGMKHAIAGAEFHELALGEPLVISAAHGDGVRELMELVLEGFPDEVEEEDSRHPKFAVI
CCCHHHHHCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEE
GRPNVGKSTLVNAILGEERVIAFDQAGTTRDSIYIDFEREGHTYTIIDTAGVRRRAKVNE
ECCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHH
MLEKFSVIKTMKAIEDANVAVLVLDAQLDISEQDATIAGFALEAGRALVVAVNKWDNLDG
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCC
EQKENVRREIARKLNFLDFAKFHYISAIEGRGVADLFKSIDEAYRAAMSKLATPKLTRVL
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
QVALERQQPPRSGLIRPKMRYAHQGGQNPPVIVVHGNALDSIPASYTRYLEHTFRKVFKL
HHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
QGTPLRVQYKSSENPFDNDEKDKPRAKPKPMSKMRGREKEVRYGKNSKK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782