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The map label for this gene is hflX [H]

Identifier: 34498987

GI number: 34498987

Start: 3840359

End: 3841489

Strand: Reverse

Name: hflX [H]

Synonym: CV_3532

Alternate gene names: 34498987

Gene position: 3841489-3840359 (Counterclockwise)

Preceding gene: 34498988

Following gene: 34498986

Centisome position: 80.86

GC content: 65.34

Gene sequence:

>1131_bases
GTGTTTGATCGTCCCGACTTAGGCGACCAGGCCATCCTGGTCAGCCTGGATTTTGGTGATGCCGACTACCAGGAAAGCGT
CGCGGAATGCGCCGAGCTGGTGCGCGGCAGCAAGGTGGAAATCCTGGGCATGGTGCAGGGCAAGCGCCAGCGCCCGGATG
CGGCGCTGTTCGCCGGCAAGGGCAAGGTGGAGGAGATTGCCTCCATGGTGCGCGCCACCGGCGCCAACGTGGTGATCTTC
AACCACGCGCTGTCTCCGGGCCAGGAGCGCAATCTGGAGCGCGCGCTGCAATGCCGCGTGATCGACCGCAACAGTCTGAT
CCTGGACATCTTCGCCCAGCGCGCGCGCAGCCACGAAGGCAAGCTCCAGGTGGAACTGGCCCAGCTGTCGCACTTGTCCA
CGCGCCTGGTGCGCGGCTGGACCCACCTGGAGCGCCAGAAGGGCGGCGTGGGCTTGCGCGGTCCCGGCGAAACCCAGCTG
GAAACCGACCGCCGGCTGCTGGGCATCCGGGTCAAGGCCTTGAAGGACAGGCTGGCCCAGGTGCAGAAGCAGCGCAATAC
GCAGCGCAGGAGCCGAAATCGGGCCGGCGTCTCCTCGGTGTCCATCGTCGGCTACACCAACGCCGGCAAATCCACGCTGT
TCAACGCGCTGACCAAGGCCAACATCTACGCCGCCGACCAGCTGTTCGCCACGCTGGACACCACCAGCCGCAAGCTGTTC
CTGAACCACGATTGCTCGGTGGTGCTGTCCGACACGGTCGGCTTCATCCGCGACCTGCCCCACACCCTGGTGGCCGCCTT
CCGCGCCACGCTGGAGGAGACGGTGCAGGCCAATCTGCTGCTGCACGTGGTGGATTGCGCCAACGAGACGCGCGACGCGC
AGATCGACGAGGTCAACAAGGTGCTGGCCGAGATCGACGCCGACGGTATTCCGCAGCTGATCGTGTGGAACAAGGGCGAC
TTGCGCGAGCTGCCGCCGGAGATCGAGCGCGACGAAGACGGCGTTGCCGTTGCCGTGCGCGTGTCGGCGCTGAAAGGCGA
GGGCCTGGAACTCTTGCGCGAGGCGATTGCCGAACGGGTGCAACCTTTCGCAAACAACCATAAAGAACCATACGAGCATG
TCGCAGAATGA

Upstream 100 bases:

>100_bases
ACCGTCCTCGCTTCGCCGATCGGGCCGATTGGCCGCATCTCAGGATGCGGCCTTTCGGCCTTTGTCATTTATCGCCGTAC
TCACGAATGGTTAGCAAACA

Downstream 100 bases:

>100_bases
CCCGAACCGTGGCCGCAACGGCCAGAATGGGCCACCGGACCTCGATGAAGTGTTCCGTGATCTGAACCGAAAACTTTCCC
GCCTGCTGGGCGGCAAGCCC

Product: GTP-binding protein hflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MFDRPDLGDQAILVSLDFGDADYQESVAECAELVRGSKVEILGMVQGKRQRPDAALFAGKGKVEEIASMVRATGANVVIF
NHALSPGQERNLERALQCRVIDRNSLILDIFAQRARSHEGKLQVELAQLSHLSTRLVRGWTHLERQKGGVGLRGPGETQL
ETDRRLLGIRVKALKDRLAQVQKQRNTQRRSRNRAGVSSVSIVGYTNAGKSTLFNALTKANIYAADQLFATLDTTSRKLF
LNHDCSVVLSDTVGFIRDLPHTLVAAFRATLEETVQANLLLHVVDCANETRDAQIDEVNKVLAEIDADGIPQLIVWNKGD
LRELPPEIERDEDGVAVAVRVSALKGEGLELLREAIAERVQPFANNHKEPYEHVAE

Sequences:

>Translated_376_residues
MFDRPDLGDQAILVSLDFGDADYQESVAECAELVRGSKVEILGMVQGKRQRPDAALFAGKGKVEEIASMVRATGANVVIF
NHALSPGQERNLERALQCRVIDRNSLILDIFAQRARSHEGKLQVELAQLSHLSTRLVRGWTHLERQKGGVGLRGPGETQL
ETDRRLLGIRVKALKDRLAQVQKQRNTQRRSRNRAGVSSVSIVGYTNAGKSTLFNALTKANIYAADQLFATLDTTSRKLF
LNHDCSVVLSDTVGFIRDLPHTLVAAFRATLEETVQANLLLHVVDCANETRDAQIDEVNKVLAEIDADGIPQLIVWNKGD
LRELPPEIERDEDGVAVAVRVSALKGEGLELLREAIAERVQPFANNHKEPYEHVAE
>Mature_376_residues
MFDRPDLGDQAILVSLDFGDADYQESVAECAELVRGSKVEILGMVQGKRQRPDAALFAGKGKVEEIASMVRATGANVVIF
NHALSPGQERNLERALQCRVIDRNSLILDIFAQRARSHEGKLQVELAQLSHLSTRLVRGWTHLERQKGGVGLRGPGETQL
ETDRRLLGIRVKALKDRLAQVQKQRNTQRRSRNRAGVSSVSIVGYTNAGKSTLFNALTKANIYAADQLFATLDTTSRKLF
LNHDCSVVLSDTVGFIRDLPHTLVAAFRATLEETVQANLLLHVVDCANETRDAQIDEVNKVLAEIDADGIPQLIVWNKGD
LRELPPEIERDEDGVAVAVRVSALKGEGLELLREAIAERVQPFANNHKEPYEHVAE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=224, Percent_Identity=37.0535714285714, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310133116, Length=222, Percent_Identity=37.3873873873874, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310124269, Length=204, Percent_Identity=38.2352941176471, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124267, Length=204, Percent_Identity=38.2352941176471, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124171, Length=204, Percent_Identity=38.2352941176471, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124169, Length=204, Percent_Identity=38.2352941176471, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1790615, Length=368, Percent_Identity=58.9673913043478, Blast_Score=410, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17561038, Length=353, Percent_Identity=30.028328611898, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24650079, Length=318, Percent_Identity=32.0754716981132, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 41589; Mature: 41589

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRPDLGDQAILVSLDFGDADYQESVAECAELVRGSKVEILGMVQGKRQRPDAALFAGK
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECC
GKVEEIASMVRATGANVVIFNHALSPGQERNLERALQCRVIDRNSLILDIFAQRARSHEG
CCHHHHHHHHHHCCCCEEEEECCCCCCHHHCHHHHHHEEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLSHLSTRLVRGWTHLERQKGGVGLRGPGETQLETDRRLLGIRVKALKDRLAQ
CEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VQKQRNTQRRSRNRAGVSSVSIVGYTNAGKSTLFNALTKANIYAADQLFATLDTTSRKLF
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEE
LNHDCSVVLSDTVGFIRDLPHTLVAAFRATLEETVQANLLLHVVDCANETRDAQIDEVNK
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCCHHHHHHH
VLAEIDADGIPQLIVWNKGDLRELPPEIERDEDGVAVAVRVSALKGEGLELLREAIAERV
HHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
QPFANNHKEPYEHVAE
HHHHCCCCCHHHHHCC
>Mature Secondary Structure
MFDRPDLGDQAILVSLDFGDADYQESVAECAELVRGSKVEILGMVQGKRQRPDAALFAGK
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECC
GKVEEIASMVRATGANVVIFNHALSPGQERNLERALQCRVIDRNSLILDIFAQRARSHEG
CCHHHHHHHHHHCCCCEEEEECCCCCCHHHCHHHHHHEEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLSHLSTRLVRGWTHLERQKGGVGLRGPGETQLETDRRLLGIRVKALKDRLAQ
CEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VQKQRNTQRRSRNRAGVSSVSIVGYTNAGKSTLFNALTKANIYAADQLFATLDTTSRKLF
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEE
LNHDCSVVLSDTVGFIRDLPHTLVAAFRATLEETVQANLLLHVVDCANETRDAQIDEVNK
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCCHHHHHHH
VLAEIDADGIPQLIVWNKGDLRELPPEIERDEDGVAVAVRVSALKGEGLELLREAIAERV
HHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
QPFANNHKEPYEHVAE
HHHHCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]