Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 34498865

GI number: 34498865

Start: 3703561

End: 3704373

Strand: Reverse

Name: pabC [H]

Synonym: CV_3410

Alternate gene names: 34498865

Gene position: 3704373-3703561 (Counterclockwise)

Preceding gene: 34498866

Following gene: 34498864

Centisome position: 77.97

GC content: 68.14

Gene sequence:

>813_bases
ATGGCGGTGCTGGTCAATGGCCTGCCTGGGGAGGCGGTGTCGGCGCTGGACCGCGGCTTCAACTACGGCGACGGCGTGTT
CCGCACCATGCAGCTGCGCCATGGCCGGCCGTGGATGTGGCGCTGGCAGTACGCGCGGCTGGCCGACGACGCCGCGAGGC
TGGCGCTGACGCTGCCGGACGAGCAGCAGTTGCTGGACGAGCTGATGGCGCTGGGCCGCGAGCACGCGCTGGCCGTGGGC
AAGATCGTGATCACCCGCGGCGCCGGCGCGCGCGGCTACGCGATGGCGGGCGCCGGCGCGCCGACGCGCGTCGTGTCGGC
GACGCCATGGGCCGGCTATCCGTCGGAGTACGGCGAGCGGGGCGTGGCCGCGCGCTGGTGCGAGCTGAGGCTGTCGCTGC
AGCCGCGCCTGGCTGGCGTCAAGCACCTGAACCGGCTGGAGAGCGTGCTGGCGCGGTCGGAGTGGAGCGATCCGGCGATA
CAGGAAGGCCTGCTGCTGGATCAGGACGGCTGGCTGGCCGAGGGCACGATGAGCAATGTCTACCTGCTGCGCGACGGCGA
GATCCAGACCCCCTTGCTGGATCGCTGCGGCGTGAACGGCGCGGTGCGGGATTGGTTGACCGATAATGTTTCAATTTTCG
GACTTAAATTTTCGGAAAGGCGACTTTCCGCCGCCGATTTGATTGACGCTGAGACGGCGTTTCTCTCCAATAGCCTGATC
GGCGTCTGGCCGCTGGCCCGTCTGGGCGAGCGGATCTGGACGCCTTCGCCTTTGCTGCAGGCATTGCGGCAAGCCTTACT
ACAACAAGCCTGA

Upstream 100 bases:

>100_bases
GCGGCGGCATCGTCGCCGACTCCGATCCCGAGCGCGAATTGCAGGAAACCCGTCACAAGGCGCGCGGCCTGCTGCGCGCG
CTGGGCGTGGAGCAGGCCTG

Downstream 100 bases:

>100_bases
TGCATGGCGCCGGGGAACGTCGGCGCGATGTTCCGCTTGCCGCGCCGGCTGGCTCCCTCTCTTCTTCCGCATCGATCCGA
TCGCGCCGGAGCGGGCGGGT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAVLVNGLPGEAVSALDRGFNYGDGVFRTMQLRHGRPWMWRWQYARLADDAARLALTLPDEQQLLDELMALGREHALAVG
KIVITRGAGARGYAMAGAGAPTRVVSATPWAGYPSEYGERGVAARWCELRLSLQPRLAGVKHLNRLESVLARSEWSDPAI
QEGLLLDQDGWLAEGTMSNVYLLRDGEIQTPLLDRCGVNGAVRDWLTDNVSIFGLKFSERRLSAADLIDAETAFLSNSLI
GVWPLARLGERIWTPSPLLQALRQALLQQA

Sequences:

>Translated_270_residues
MAVLVNGLPGEAVSALDRGFNYGDGVFRTMQLRHGRPWMWRWQYARLADDAARLALTLPDEQQLLDELMALGREHALAVG
KIVITRGAGARGYAMAGAGAPTRVVSATPWAGYPSEYGERGVAARWCELRLSLQPRLAGVKHLNRLESVLARSEWSDPAI
QEGLLLDQDGWLAEGTMSNVYLLRDGEIQTPLLDRCGVNGAVRDWLTDNVSIFGLKFSERRLSAADLIDAETAFLSNSLI
GVWPLARLGERIWTPSPLLQALRQALLQQA
>Mature_269_residues
AVLVNGLPGEAVSALDRGFNYGDGVFRTMQLRHGRPWMWRWQYARLADDAARLALTLPDEQQLLDELMALGREHALAVGK
IVITRGAGARGYAMAGAGAPTRVVSATPWAGYPSEYGERGVAARWCELRLSLQPRLAGVKHLNRLESVLARSEWSDPAIQ
EGLLLDQDGWLAEGTMSNVYLLRDGEIQTPLLDRCGVNGAVRDWLTDNVSIFGLKFSERRLSAADLIDAETAFLSNSLIG
VWPLARLGERIWTPSPLLQALRQALLQQA

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=259, Percent_Identity=31.6602316602317, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI48994963, Length=247, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29715; Mature: 29584

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVNGLPGEAVSALDRGFNYGDGVFRTMQLRHGRPWMWRWQYARLADDAARLALTLPD
CEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHCCHHEEEEECCC
EQQLLDELMALGREHALAVGKIVITRGAGARGYAMAGAGAPTRVVSATPWAGYPSEYGER
HHHHHHHHHHHCHHHHHEEEEEEEECCCCCCCEEEECCCCCCEEEECCCCCCCCHHHCCC
GVAARWCELRLSLQPRLAGVKHLNRLESVLARSEWSDPAIQEGLLLDQDGWLAEGTMSNV
CHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCEECCCCCCE
YLLRDGEIQTPLLDRCGVNGAVRDWLTDNVSIFGLKFSERRLSAADLIDAETAFLSNSLI
EEEECCCCCCCHHHHCCCCHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCH
GVWPLARLGERIWTPSPLLQALRQALLQQA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVLVNGLPGEAVSALDRGFNYGDGVFRTMQLRHGRPWMWRWQYARLADDAARLALTLPD
EEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHCCHHEEEEECCC
EQQLLDELMALGREHALAVGKIVITRGAGARGYAMAGAGAPTRVVSATPWAGYPSEYGER
HHHHHHHHHHHCHHHHHEEEEEEEECCCCCCCEEEECCCCCCEEEECCCCCCCCHHHCCC
GVAARWCELRLSLQPRLAGVKHLNRLESVLARSEWSDPAIQEGLLLDQDGWLAEGTMSNV
CHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCEECCCCCCE
YLLRDGEIQTPLLDRCGVNGAVRDWLTDNVSIFGLKFSERRLSAADLIDAETAFLSNSLI
EEEECCCCCCCHHHHCCCCHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCH
GVWPLARLGERIWTPSPLLQALRQALLQQA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]