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The map label for this gene is dcp2 [H]

Identifier: 34498836

GI number: 34498836

Start: 3675966

End: 3677981

Strand: Direct

Name: dcp2 [H]

Synonym: CV_3381

Alternate gene names: 34498836

Gene position: 3675966-3677981 (Clockwise)

Preceding gene: 34498835

Following gene: 34498837

Centisome position: 77.37

GC content: 68.3

Gene sequence:

>2016_bases
ATGAACAACCCGCTGCTGCAAGCCTGGGACACGCCACACCAGCTGCCGCCGTTCGATCTCATTCGCGCCGAGCACTTCGC
GCCCGCCATCGAGCAGTTGATGGCCGAGCACAGGCGGGCCATCTCCGCCATCGCCGCCCAGACCGGCCCCGTCAGCTTCG
CCAACACCGCGGAAGCGCTGGACGCCGCCGCGCTGCCGCTGAAACGCGTGACGCTGGTGCTGCACAATCTGTGCAGTTCG
CACTCCAGCCCGGAACTGCGCGCCGTCGAGCGCGAGCTGGCGCCGCGGCTGGCCGCCCACCACAGCGCCATTTTCCTGGA
CACGCAACTGTTCGCCCGACTGGACGAGGCGATGCGCGCGGCGCCCGGCTGGGAGTTGAGCGAGGAACAACGCCGCCTGC
TGCAGCGCTGGCACCTGGACTTCACCTTGGCCGGCGCCCGGCTGCAAGGCGAAGCGAGGCGCGAATTCGCCGATTGCGTC
GCCGAGCTGGCGTCGCTGTCCGCCGCCTTCGGCCAGAACGTGCTGGCCGACGAAACGGAGTACGCGCTCCAATTGCAGAA
CGAGGCCGATCTCGCCGGCCTGCCCGGCTGGCTGCGGGACGCGTCGGCCCGCGCCGCGCGCGAGCGCGGCTTGGACGGCC
ACGCCATCACGCTGGCGCGCTCCAGCACGGTCGCCTTCCTCACCCACTCCAGCCGCGCCGACCTGCGCCAGGCGCTGTGG
CGCGCCTGGACTTCGCGCGGAACGACACAGGCGCGCGACAACCGCCCTCTGATCCGCCGCATGCTGCAACTGCGCCAACG
CCAGGCCCGTCTGCTCGGCTACGCCAATTATGCCGATTACGCGCTGAGCGACCGCATGGCGGGTTCGCCGCAAGCGGTGT
ACCGGCTGCTGGAGCCGACCTGGGAAGCCGCGCTCGCCCAGTTCGCGCGGGAAAAGGCGCTGTTGCAGGAGACGGCCCGG
CGCGAGGGGCTGCCCGATGACATCGCGCCCTGGGACTGGCGCTATCTGGCGGAGAAGGTCAGGCTGGAGCGCTACGCGCT
GGACGACGCCGAAATCAAGCCCTACTTCAGCCTGGACAATATGATCGCCGCAATGTTCGATGTCGCCGGCCGTCTGTTCG
GCCTGAGCTTCGCCGAGCGCGGCGACCTGCCGCGCTACCACCCGGACCTGCGCGGCTGGGAGGTGCTGCGCGACGGCGCC
GTCATCGGCGTGTTCCTCAGCGACAACTTCGCCCGCCCCGGCAAGAAGGGCGGCGCCTGGATGAGCGTCTACCGCGCCCA
GGGCCGCCATGGCGGACTGTCTCTGCCCATCGTGGTCAACAACACCAACTTTTCCAAGGGCGAGCCGACGCTGCTGGGCC
TGGACGACGTGCGCACGCTATTCCATGAATTCGGCCACGCGCTGCATGGTCTGCTGTCGGACGTAGACTATCAGCGCCTG
TCCGGCACCCAGGTGCTGCGCGACTTCGTCGAGCTGCCGTCCCAGCTGATGGAAAACTGGGCCTGGACGCCGGACATCCT
GGACAGGCACGCGCGGCACGCAGAAACCGACCGTCCCATGCCAGAGGCGCTGCGCGCCCGCATTCTCGCCGCGCAGAACT
TCCAGCAGGGCTATGCCACCGTGCGCTACACGATATCGGCGCTGCTGGATCTGGCGCTGCACCAGGAGGCCGACGGCGTC
GACGACCCCGCGGCCTTCGAAACGGAACTATGCCAGCATTACGGCCTGCCGGCGGAAGCCGGGCTTGCCCACTCGCTGCC
CCACTTCAACCACCTGTTCAACGGCGGCTACGCGGCTGGCTACTACGTTTACCTATGGGCGGAAGTGCTGGAGGCCGAAG
CTTTCGCCCGCTTCGAGGAAAGCGGCGACCTGTTCGATCCGGAGCTCGCCGCCTCGCTGTGCCGCCACATCTACAGCGCA
GGCAACGCCCGCAACCCCAAGCAAGCCTTCCAGGCTTTCTCCGGGCGTGAACCATCCGTGCAGGCCATGCTGAAAAAAAG
AGGGTTGACCGTCTAG

Upstream 100 bases:

>100_bases
GCGGAAGCGATGCTGAAAAACCGCGGCCTGCTGTAAGGGACCGAGCCGCCGGGACCGCCCGGCGGCTGCTACATTGCCGC
TCCGGCGCCAAGGAATCATC

Downstream 100 bases:

>100_bases
CCGCAGCCGCGCCGCAACACTCATCCCCCTCCCGCGGGCGGGGGAATGAAAATGTCATTGATCTATTCCGCCTCCGCCGG
GATACTGACGCATCCGCGGC

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MNNPLLQAWDTPHQLPPFDLIRAEHFAPAIEQLMAEHRRAISAIAAQTGPVSFANTAEALDAAALPLKRVTLVLHNLCSS
HSSPELRAVERELAPRLAAHHSAIFLDTQLFARLDEAMRAAPGWELSEEQRRLLQRWHLDFTLAGARLQGEARREFADCV
AELASLSAAFGQNVLADETEYALQLQNEADLAGLPGWLRDASARAARERGLDGHAITLARSSTVAFLTHSSRADLRQALW
RAWTSRGTTQARDNRPLIRRMLQLRQRQARLLGYANYADYALSDRMAGSPQAVYRLLEPTWEAALAQFAREKALLQETAR
REGLPDDIAPWDWRYLAEKVRLERYALDDAEIKPYFSLDNMIAAMFDVAGRLFGLSFAERGDLPRYHPDLRGWEVLRDGA
VIGVFLSDNFARPGKKGGAWMSVYRAQGRHGGLSLPIVVNNTNFSKGEPTLLGLDDVRTLFHEFGHALHGLLSDVDYQRL
SGTQVLRDFVELPSQLMENWAWTPDILDRHARHAETDRPMPEALRARILAAQNFQQGYATVRYTISALLDLALHQEADGV
DDPAAFETELCQHYGLPAEAGLAHSLPHFNHLFNGGYAAGYYVYLWAEVLEAEAFARFEESGDLFDPELAASLCRHIYSA
GNARNPKQAFQAFSGREPSVQAMLKKRGLTV

Sequences:

>Translated_671_residues
MNNPLLQAWDTPHQLPPFDLIRAEHFAPAIEQLMAEHRRAISAIAAQTGPVSFANTAEALDAAALPLKRVTLVLHNLCSS
HSSPELRAVERELAPRLAAHHSAIFLDTQLFARLDEAMRAAPGWELSEEQRRLLQRWHLDFTLAGARLQGEARREFADCV
AELASLSAAFGQNVLADETEYALQLQNEADLAGLPGWLRDASARAARERGLDGHAITLARSSTVAFLTHSSRADLRQALW
RAWTSRGTTQARDNRPLIRRMLQLRQRQARLLGYANYADYALSDRMAGSPQAVYRLLEPTWEAALAQFAREKALLQETAR
REGLPDDIAPWDWRYLAEKVRLERYALDDAEIKPYFSLDNMIAAMFDVAGRLFGLSFAERGDLPRYHPDLRGWEVLRDGA
VIGVFLSDNFARPGKKGGAWMSVYRAQGRHGGLSLPIVVNNTNFSKGEPTLLGLDDVRTLFHEFGHALHGLLSDVDYQRL
SGTQVLRDFVELPSQLMENWAWTPDILDRHARHAETDRPMPEALRARILAAQNFQQGYATVRYTISALLDLALHQEADGV
DDPAAFETELCQHYGLPAEAGLAHSLPHFNHLFNGGYAAGYYVYLWAEVLEAEAFARFEESGDLFDPELAASLCRHIYSA
GNARNPKQAFQAFSGREPSVQAMLKKRGLTV
>Mature_671_residues
MNNPLLQAWDTPHQLPPFDLIRAEHFAPAIEQLMAEHRRAISAIAAQTGPVSFANTAEALDAAALPLKRVTLVLHNLCSS
HSSPELRAVERELAPRLAAHHSAIFLDTQLFARLDEAMRAAPGWELSEEQRRLLQRWHLDFTLAGARLQGEARREFADCV
AELASLSAAFGQNVLADETEYALQLQNEADLAGLPGWLRDASARAARERGLDGHAITLARSSTVAFLTHSSRADLRQALW
RAWTSRGTTQARDNRPLIRRMLQLRQRQARLLGYANYADYALSDRMAGSPQAVYRLLEPTWEAALAQFAREKALLQETAR
REGLPDDIAPWDWRYLAEKVRLERYALDDAEIKPYFSLDNMIAAMFDVAGRLFGLSFAERGDLPRYHPDLRGWEVLRDGA
VIGVFLSDNFARPGKKGGAWMSVYRAQGRHGGLSLPIVVNNTNFSKGEPTLLGLDDVRTLFHEFGHALHGLLSDVDYQRL
SGTQVLRDFVELPSQLMENWAWTPDILDRHARHAETDRPMPEALRARILAAQNFQQGYATVRYTISALLDLALHQEADGV
DDPAAFETELCQHYGLPAEAGLAHSLPHFNHLFNGGYAAGYYVYLWAEVLEAEAFARFEESGDLFDPELAASLCRHIYSA
GNARNPKQAFQAFSGREPSVQAMLKKRGLTV

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=670, Percent_Identity=28.5074626865672, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI14149738, Length=671, Percent_Identity=26.5275707898659, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI156105687, Length=643, Percent_Identity=25.0388802488336, Blast_Score=150, Evalue=6e-36,
Organism=Escherichia coli, GI1787819, Length=680, Percent_Identity=35.5882352941176, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=33.8192419825073, Blast_Score=370, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI32565901, Length=576, Percent_Identity=22.0486111111111, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319793, Length=616, Percent_Identity=25.974025974026, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322715, Length=476, Percent_Identity=25, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356111, Length=687, Percent_Identity=23.1441048034935, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129717, Length=430, Percent_Identity=27.6744186046512, Blast_Score=132, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 75053; Mature: 75053

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPLLQAWDTPHQLPPFDLIRAEHFAPAIEQLMAEHRRAISAIAAQTGPVSFANTAEAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DAAALPLKRVTLVLHNLCSSHSSPELRAVERELAPRLAAHHSAIFLDTQLFARLDEAMRA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHEEHHHHHHHHHHHHHC
APGWELSEEQRRLLQRWHLDFTLAGARLQGEARREFADCVAELASLSAAFGQNVLADETE
CCCCCCCHHHHHHHHHHCCCEEEECCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHH
YALQLQNEADLAGLPGWLRDASARAARERGLDGHAITLARSSTVAFLTHSSRADLRQALW
HHEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCHHHHHHHHH
RAWTSRGTTQARDNRPLIRRMLQLRQRQARLLGYANYADYALSDRMAGSPQAVYRLLEPT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
WEAALAQFAREKALLQETARREGLPDDIAPWDWRYLAEKVRLERYALDDAEIKPYFSLDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MIAAMFDVAGRLFGLSFAERGDLPRYHPDLRGWEVLRDGAVIGVFLSDNFARPGKKGGAW
HHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHH
MSVYRAQGRHGGLSLPIVVNNTNFSKGEPTLLGLDDVRTLFHEFGHALHGLLSDVDYQRL
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCHHHHH
SGTQVLRDFVELPSQLMENWAWTPDILDRHARHAETDRPMPEALRARILAAQNFQQGYAT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRYTISALLDLALHQEADGVDDPAAFETELCQHYGLPAEAGLAHSLPHFNHLFNGGYAAG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHCCCCHHH
YYVYLWAEVLEAEAFARFEESGDLFDPELAASLCRHIYSAGNARNPKQAFQAFSGREPSV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHH
QAMLKKRGLTV
HHHHHHCCCCC
>Mature Secondary Structure
MNNPLLQAWDTPHQLPPFDLIRAEHFAPAIEQLMAEHRRAISAIAAQTGPVSFANTAEAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DAAALPLKRVTLVLHNLCSSHSSPELRAVERELAPRLAAHHSAIFLDTQLFARLDEAMRA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHEEHHHHHHHHHHHHHC
APGWELSEEQRRLLQRWHLDFTLAGARLQGEARREFADCVAELASLSAAFGQNVLADETE
CCCCCCCHHHHHHHHHHCCCEEEECCHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHH
YALQLQNEADLAGLPGWLRDASARAARERGLDGHAITLARSSTVAFLTHSSRADLRQALW
HHEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCHHHHHHHHH
RAWTSRGTTQARDNRPLIRRMLQLRQRQARLLGYANYADYALSDRMAGSPQAVYRLLEPT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
WEAALAQFAREKALLQETARREGLPDDIAPWDWRYLAEKVRLERYALDDAEIKPYFSLDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MIAAMFDVAGRLFGLSFAERGDLPRYHPDLRGWEVLRDGAVIGVFLSDNFARPGKKGGAW
HHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHH
MSVYRAQGRHGGLSLPIVVNNTNFSKGEPTLLGLDDVRTLFHEFGHALHGLLSDVDYQRL
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCHHHHH
SGTQVLRDFVELPSQLMENWAWTPDILDRHARHAETDRPMPEALRARILAAQNFQQGYAT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRYTISALLDLALHQEADGVDDPAAFETELCQHYGLPAEAGLAHSLPHFNHLFNGGYAAG
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHCCCCHHH
YYVYLWAEVLEAEAFARFEESGDLFDPELAASLCRHIYSAGNARNPKQAFQAFSGREPSV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHH
QAMLKKRGLTV
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537804; 11677609 [H]