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The map label for this gene is hflK [H]

Identifier: 34498767

GI number: 34498767

Start: 3604597

End: 3605622

Strand: Direct

Name: hflK [H]

Synonym: CV_3312

Alternate gene names: 34498767

Gene position: 3604597-3605622 (Clockwise)

Preceding gene: 34498764

Following gene: 34498768

Centisome position: 75.87

GC content: 69.01

Gene sequence:

>1026_bases
ATGCCCGAAACCCGCCCCAACACACCGCCCCCCCCCTCCCCGTTCGCCGCGCTGCGGCTGCGGCTGGACTACACGCTGGA
ACTGCTGGGCATGCGCGGAAAAGGCCTGGCCTTGCTCGCCGGCATGATCGCCATCCTCTGGCTGGCCTCCGGCATCTACC
GCGTGGAGCCCGACGAGCAGGGCGTGGTGCAGCGCTTCGGCCGCTGGACCGACACCACCGCGGCCGGCCTGCACTACCAC
CTGCCCTGGCCGATGGAGACCATCCAGCTGCCCAAAGTTACCCAGATCAAGCAGCTGAAGCTGGCCAATCTGTATGAAAG
CGGCCCGCCCGATGCCGCCGACCCGCGCGAAAAGCAGATGCTGACCGGCGACGAGAACATCATCGAGGCCGACTGCGCGG
TGTTCTGGCGCATCAAGGACGCCGGCCGGTTCCTGTTCCGCGCCAACAAGCCGGAAGAAGCGCTGCGCATCACCGCCGAA
GGCGCGCTGCGCGAGGTGATCTCCCGCACGCCCATCCAGGCGGCGATGTCCAACCGCCGCCAGCAGGTGGCCGAGGAGGC
CCGCGAGCTGATCCAGCAGCGGCTGGACGCGCAGCAGGCCGGCATCCTGATCACCCAGGTGCAGCTGCAGCGGGTCGACC
CGCCGGCGGCGGTGATCGACGCCTTCAACGACGTGCAGCGCGCCCGCGCCGACCAGGAGCGCGCGCGCAACGAGGCCCAG
GCCTACAGCAACGACATCCTGCCCAAGGCGCGCGGCGAGGCCGAGCGCATCCGCCAGGAGGCCGAAGCCTACCGCAGCCA
GGTGGTCAACCTGGCCCAGGGCGAGGCCAGGCGCTTCGACTCGGTGTACCAGACCTATGCCCAGGCCAAGGACGTCACCG
CGTGGCGGCTGTACCTGGAAAGCATGGACGACATGCTGAAGAAGGCCAGCAAGGTGGTGATAGACGGCAGCGGCAAGAGC
GGCGCCGGCGTGTTGCCGCTGCTGCAGCTGCAGGACAAACCCAAGGCCGGCAAGGAGAACCGCTGA

Upstream 100 bases:

>100_bases
GGCATTGCCGCATCCCTAAATACGCCGACGCTGTCATCCGTCCGGCATTTGCCGCGTTAAACCCGACAGCAAGCATGGTT
AAAACCAGGACAAGCCCTTG

Downstream 100 bases:

>100_bases
TGGATAAGCAGTGGCGCGGAATCGGCTGGGCGGCGGGCCTGGCGGTCGTATGGCTGGCGCTGTCGGCGCAATACACGCTG
AACGAGGGGCAGAAGGCGCT

Product: transmembrane protein HflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MPETRPNTPPPPSPFAALRLRLDYTLELLGMRGKGLALLAGMIAILWLASGIYRVEPDEQGVVQRFGRWTDTTAAGLHYH
LPWPMETIQLPKVTQIKQLKLANLYESGPPDAADPREKQMLTGDENIIEADCAVFWRIKDAGRFLFRANKPEEALRITAE
GALREVISRTPIQAAMSNRRQQVAEEARELIQQRLDAQQAGILITQVQLQRVDPPAAVIDAFNDVQRARADQERARNEAQ
AYSNDILPKARGEAERIRQEAEAYRSQVVNLAQGEARRFDSVYQTYAQAKDVTAWRLYLESMDDMLKKASKVVIDGSGKS
GAGVLPLLQLQDKPKAGKENR

Sequences:

>Translated_341_residues
MPETRPNTPPPPSPFAALRLRLDYTLELLGMRGKGLALLAGMIAILWLASGIYRVEPDEQGVVQRFGRWTDTTAAGLHYH
LPWPMETIQLPKVTQIKQLKLANLYESGPPDAADPREKQMLTGDENIIEADCAVFWRIKDAGRFLFRANKPEEALRITAE
GALREVISRTPIQAAMSNRRQQVAEEARELIQQRLDAQQAGILITQVQLQRVDPPAAVIDAFNDVQRARADQERARNEAQ
AYSNDILPKARGEAERIRQEAEAYRSQVVNLAQGEARRFDSVYQTYAQAKDVTAWRLYLESMDDMLKKASKVVIDGSGKS
GAGVLPLLQLQDKPKAGKENR
>Mature_340_residues
PETRPNTPPPPSPFAALRLRLDYTLELLGMRGKGLALLAGMIAILWLASGIYRVEPDEQGVVQRFGRWTDTTAAGLHYHL
PWPMETIQLPKVTQIKQLKLANLYESGPPDAADPREKQMLTGDENIIEADCAVFWRIKDAGRFLFRANKPEEALRITAEG
ALREVISRTPIQAAMSNRRQQVAEEARELIQQRLDAQQAGILITQVQLQRVDPPAAVIDAFNDVQRARADQERARNEAQA
YSNDILPKARGEAERIRQEAEAYRSQVVNLAQGEARRFDSVYQTYAQAKDVTAWRLYLESMDDMLKKASKVVIDGSGKSG
AGVLPLLQLQDKPKAGKENR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=281, Percent_Identity=29.8932384341637, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 38207; Mature: 38076

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETRPNTPPPPSPFAALRLRLDYTLELLGMRGKGLALLAGMIAILWLASGIYRVEPDEQ
CCCCCCCCCCCCCCHHHHEEHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCEEECCCCH
GVVQRFGRWTDTTAAGLHYHLPWPMETIQLPKVTQIKQLKLANLYESGPPDAADPREKQM
HHHHHCCCCCCCCCCCEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LTGDENIIEADCAVFWRIKDAGRFLFRANKPEEALRITAEGALREVISRTPIQAAMSNRR
CCCCCCCEECCCEEEEEECCCCCEEEECCCCHHHHEEHHHHHHHHHHHCCCHHHHHHHHH
QQVAEEARELIQQRLDAQQAGILITQVQLQRVDPPAAVIDAFNDVQRARADQERARNEAQ
HHHHHHHHHHHHHHHCHHHHCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYSNDILPKARGEAERIRQEAEAYRSQVVNLAQGEARRFDSVYQTYAQAKDVTAWRLYLE
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
SMDDMLKKASKVVIDGSGKSGAGVLPLLQLQDKPKAGKENR
HHHHHHHHHCEEEEECCCCCCCCCCHHHEECCCCCCCCCCC
>Mature Secondary Structure 
PETRPNTPPPPSPFAALRLRLDYTLELLGMRGKGLALLAGMIAILWLASGIYRVEPDEQ
CCCCCCCCCCCCCHHHHEEHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCEEECCCCH
GVVQRFGRWTDTTAAGLHYHLPWPMETIQLPKVTQIKQLKLANLYESGPPDAADPREKQM
HHHHHCCCCCCCCCCCEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LTGDENIIEADCAVFWRIKDAGRFLFRANKPEEALRITAEGALREVISRTPIQAAMSNRR
CCCCCCCEECCCEEEEEECCCCCEEEECCCCHHHHEEHHHHHHHHHHHCCCHHHHHHHHH
QQVAEEARELIQQRLDAQQAGILITQVQLQRVDPPAAVIDAFNDVQRARADQERARNEAQ
HHHHHHHHHHHHHHHCHHHHCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AYSNDILPKARGEAERIRQEAEAYRSQVVNLAQGEARRFDSVYQTYAQAKDVTAWRLYLE
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
SMDDMLKKASKVVIDGSGKSGAGVLPLLQLQDKPKAGKENR
HHHHHHHHHCEEEEECCCCCCCCCCHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]