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The map label for this gene is ocd

Identifier: 34498704

GI number: 34498704

Start: 3532866

End: 3533810

Strand: Reverse

Name: ocd

Synonym: CV_3249

Alternate gene names: NA

Gene position: 3533810-3532866 (Counterclockwise)

Preceding gene: 34498705

Following gene: 34498701

Centisome position: 74.38

GC content: 71.96

Gene sequence:

>945_bases
ATGAAGCTGCTTGACAAGAACGCCATCATCGCGCGCTTCGACGCCGACCATGCGCTGGCCAGGGTGAAGGCCGGCTTCAT
CGCCTACTCGCGCGGCCAGGTCCAGTCTGCGCCGGTGCAGAATTTCCATTTCGCCGGCGCCAACGGCGATTGCTGCGTCA
AATCGGCGCATATCGCCGGCGAGGAGGCGCTGGTGGTCAAGATCTCCACCGGCTTCTACGACAACCCGTCGCGCGGGTTG
CCCAGCAACGACGGCTTGGTGCTGGCGCTGTCGGCCACGGACGGCCGGGTGCTGGCGCTGCTGCAGGACCAGGGCTGGCT
GACCACGATGCGGACCGCGCTGGCCGGGCGGCTGGTCGCCGGCTTGCTGGCGCCGTCGCGGGTGGAGGCGATAGGCCTGC
TGGGCGCGGGCGAACAGGCCCGCGCCCAGCTGGAGCAGCTACGGGCGGTCACCGACTGCCGCGAAGTCCGGGTATGGAGC
CGGCAGCCGGAGCAGGCCGCCGCCTTCTGCGCCTTCGCCGCGCAACTGGGCTTCCGCGCGCTCGCGGCGGCCGATCCGCG
CGCGGTGGCGGCGGAGGCGAACCTGATCGTCACGGCGACGCCGTCGCGCGGGCCGCTGCTGCAGCGCGGCTGGATACGGC
CGGGCACGCACATCACTGCGCTGGGCGCGGACGGGCCGGGCAAACAGGAGCTGGACCCGGCCATCGCGGCCGACGCGAAT
GTGGTGGTCGCCGATTCGCTGGCGCAGTGCGCGGCCTACGGCGAATTGTCCCACGCGGTGAAGGCCGGCCTGCTGGCGCC
GTCCCGCATCGTCGAACTGGGCGATGCGCTGGCCAGCGGAGTGCGCTTGCGGCAGAACGACGAGCAGATCACGCTGGCCG
ATCTGACCGGCATCGCTGCCCAGGATGCGGCCATCGCGGCCAGCGTGCTGGCGCCGGGCGGCTGA

Upstream 100 bases:

>100_bases
GCGGGGCTGTTCCAGCTGGCCGAGGCATATCGCGGCCGGCCGGTGGCGGTGGTGCTGTGCGGCCGCAACATCAAGCTGGA
GACTTTCCTGGAGGCTTGCC

Downstream 100 bases:

>100_bases
GATCCCGGTTTCAGCCGCCCGGCGGCTGTCCGCCGCCTTCGATGGACTGGACGATGGCCAGCGCCTCTGCGAAGTCGAAC
CCCCGCATGCGCCGCTCCAG

Product: ornithine cyclodeaminase

Products: L-proline; NH3

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKLLDKNAIIARFDADHALARVKAGFIAYSRGQVQSAPVQNFHFAGANGDCCVKSAHIAGEEALVVKISTGFYDNPSRGL
PSNDGLVLALSATDGRVLALLQDQGWLTTMRTALAGRLVAGLLAPSRVEAIGLLGAGEQARAQLEQLRAVTDCREVRVWS
RQPEQAAAFCAFAAQLGFRALAAADPRAVAAEANLIVTATPSRGPLLQRGWIRPGTHITALGADGPGKQELDPAIAADAN
VVVADSLAQCAAYGELSHAVKAGLLAPSRIVELGDALASGVRLRQNDEQITLADLTGIAAQDAAIAASVLAPGG

Sequences:

>Translated_314_residues
MKLLDKNAIIARFDADHALARVKAGFIAYSRGQVQSAPVQNFHFAGANGDCCVKSAHIAGEEALVVKISTGFYDNPSRGL
PSNDGLVLALSATDGRVLALLQDQGWLTTMRTALAGRLVAGLLAPSRVEAIGLLGAGEQARAQLEQLRAVTDCREVRVWS
RQPEQAAAFCAFAAQLGFRALAAADPRAVAAEANLIVTATPSRGPLLQRGWIRPGTHITALGADGPGKQELDPAIAADAN
VVVADSLAQCAAYGELSHAVKAGLLAPSRIVELGDALASGVRLRQNDEQITLADLTGIAAQDAAIAASVLAPGG
>Mature_314_residues
MKLLDKNAIIARFDADHALARVKAGFIAYSRGQVQSAPVQNFHFAGANGDCCVKSAHIAGEEALVVKISTGFYDNPSRGL
PSNDGLVLALSATDGRVLALLQDQGWLTTMRTALAGRLVAGLLAPSRVEAIGLLGAGEQARAQLEQLRAVTDCREVRVWS
RQPEQAAAFCAFAAQLGFRALAAADPRAVAAEANLIVTATPSRGPLLQRGWIRPGTHITALGADGPGKQELDPAIAADAN
VVVADSLAQCAAYGELSHAVKAGLLAPSRIVELGDALASGVRLRQNDEQITLADLTGIAAQDAAIAASVLAPGG

Specific function: Unknown

COG id: COG2423

COG function: function code E; Predicted ornithine cyclodeaminase, mu-crystallin homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ornithine cyclodeaminase family [H]

Homologues:

Organism=Homo sapiens, GI62241008, Length=259, Percent_Identity=32.4324324324324, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4503065, Length=263, Percent_Identity=32.319391634981, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014334
- InterPro:   IPR016040
- InterPro:   IPR003462 [H]

Pfam domain/function: PF02423 OCD_Mu_crystall [H]

EC number: 4.3.1.12

Molecular weight: Translated: 32463; Mature: 32463

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLDKNAIIARFDADHALARVKAGFIAYSRGQVQSAPVQNFHFAGANGDCCVKSAHIAG
CCCCCCCCEEEEECCHHHHHHHHHCEEEEECCCCCCCCCCCEEEECCCCCEEEEECCCCC
EEALVVKISTGFYDNPSRGLPSNDGLVLALSATDGRVLALLQDQGWLTTMRTALAGRLVA
CCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHH
GLLAPSRVEAIGLLGAGEQARAQLEQLRAVTDCREVRVWSRQPEQAAAFCAFAAQLGFRA
HHCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LAAADPRAVAAEANLIVTATPSRGPLLQRGWIRPGTHITALGADGPGKQELDPAIAADAN
HHCCCCCEEEECCCEEEEECCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCC
VVVADSLAQCAAYGELSHAVKAGLLAPSRIVELGDALASGVRLRQNDEQITLADLTGIAA
EEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCH
QDAAIAASVLAPGG
HHHHHHHHCCCCCC
>Mature Secondary Structure
MKLLDKNAIIARFDADHALARVKAGFIAYSRGQVQSAPVQNFHFAGANGDCCVKSAHIAG
CCCCCCCCEEEEECCHHHHHHHHHCEEEEECCCCCCCCCCCEEEECCCCCEEEEECCCCC
EEALVVKISTGFYDNPSRGLPSNDGLVLALSATDGRVLALLQDQGWLTTMRTALAGRLVA
CCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHH
GLLAPSRVEAIGLLGAGEQARAQLEQLRAVTDCREVRVWSRQPEQAAAFCAFAAQLGFRA
HHCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LAAADPRAVAAEANLIVTATPSRGPLLQRGWIRPGTHITALGADGPGKQELDPAIAADAN
HHCCCCCEEEECCCEEEEECCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCC
VVVADSLAQCAAYGELSHAVKAGLLAPSRIVELGDALASGVRLRQNDEQITLADLTGIAA
EEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCH
QDAAIAASVLAPGG
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-ornithine

Specific reaction: L-ornithine = L-proline + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]