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The map label for this gene is nuoL [H]

Identifier: 34498676

GI number: 34498676

Start: 3502805

End: 3504304

Strand: Reverse

Name: nuoL [H]

Synonym: CV_3221

Alternate gene names: 34498676

Gene position: 3504304-3502805 (Counterclockwise)

Preceding gene: 34498678

Following gene: 34498675

Centisome position: 73.76

GC content: 70.93

Gene sequence:

>1500_bases
ATGCCCCAAACCCTGCTTGCCGCGTTGCCATACGCGATCGCGCTGGCCTGGTTGCTGCCCGCCCTGTGGCCGGGCCGCGC
GCTGCCGCGCCACTGGCAGGCCGCCGAAATCGCCGCGCTGGCCGGCGGCCTGCTGCTGCTTCCTCTTATCTTTCTGCCCA
CGCCTGCGCCATGGTTCGCCGCCGCCTGGCTGATGCAGGCGCTGATCCAGCTGCTGGGCTGGATGGTGCTGCGCTACTCG
CGCCGCTATATGCAAGGCGAGCCGGGCCAGGCGCGCTTCTTGCGCGCCATCGGCTGCTTGCTGGCGGCGGTGACGCTGGT
GGTGCAAGCCAGCCACCTGTTGCTGATGGCGCTGGCCTGGATCGCCTGCAGCCTGGCCTTGCAGACGCTGCTCACCTTTT
ATCCCGGCCGCCCGGCGGCGCGCCTGGCCGCCCGCCGCGAATGGCGCGCCAGCCGGCTGGCCGAATGCTTGTTGCTGGGC
GCGCTGTTGCTGTGGGCGCTGGCCGGCGGCAGCCTCAGCCTGCTGCCCGGCTCGCCGCAGGCGTTGGCCGACGGCGCGCA
GGGCTACGCCGCGGCGGCCGGCCTGCTGCTGGCGGCGGCGGTGGCGATCAAGACCGCCCAGTTGCCCTTCCACGGTTGGC
TGACCCAGGTGATGGAAGCGCCGACGCCGATTTCCGCGCTGCTGCACGCCGGGGTGGTCAATCTGGGCGGCATGGTGCTG
ATCAAGGCGGCGCCGCTGCTGCAAGCCGCGCCGCCGGCCAACCTCCTGCTGATGCTGTGGGGCGGGGCCAGCGCGCTGTT
GTGCTGCGTGGTGATGCTGACGCGCATCAGCATCAAGCTGCGCTTGGCCTGGTCGACCTGCGCGCAAATGGGTTTCATGC
TGCTGGAAATCGGCATGGGCTGGTATGCGCTGGCCTTGCTGCATCTGCTGGCCCACTCCTTCTACAAGGCCCACGCCTTC
CTGCTGGCCGGCGAAACGGCGCGCGACAGCGCGGCGCGGCGCATGCTGGGCCAGGAAAGCGCCGACGGAGTCCTCCCGCA
TCTGGCCCGGGGCCTGATTGCGGCCGCGCTGCTGGCGGCTTCGCAATGGCTGTGGCAGCGCTGGATTCCCGCAGCCGCCT
TGCCGCCGCTGTTCTGGCTGGCGATGGGCCTGGGCATGGGCGCGCTGCTGCGCGGCGGGGCCGGCTGGCTGGCGGCGCTG
GCCTTGAGCCAGTCCTATCTGCTGCTGCACGCGCTGGCGGCGCGGATCCTGCCGCTGCATGGCCCGACGCCGCCGGAGTG
GGCGCAAGCCTTGCTGGCCGCGCTGTTCCTGCTCGTCTTTTTGCTACAGGGTTGGCTGCTGCGCCATCCCCAAGGCGCGC
TGGCGCGCCGGATCTATCCGCATGCCTTCGCCGGTTTCCACCTGGACGAATGGTGGTGCATGCTTGGCCGCCGCCTTCCG
CGTCCGCCCGCGCCCTTCGCCCTGAAATGGCCTCAACTGCGGGAGAGCAGCCGTGATTGA

Upstream 100 bases:

>100_bases
CTCATTGTTCTAAAATAAAGAATGAAAACTAATATTTAATCTATTTTACTGAACATATTCGCTCAGGCAAAGTTCGAGCA
GGAAAACAACGGAGCCTTCC

Downstream 100 bases:

>100_bases
CAGCAAGGCCATAGACCAAGCGCTGGCCGCCATCGCGCCGGCCTGGCCGCTGGACAGCCTGGTGGCCAGCTCGCCCTACT
GGGGTCTGCGCGAACAGTCT

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MPQTLLAALPYAIALAWLLPALWPGRALPRHWQAAEIAALAGGLLLLPLIFLPTPAPWFAAAWLMQALIQLLGWMVLRYS
RRYMQGEPGQARFLRAIGCLLAAVTLVVQASHLLLMALAWIACSLALQTLLTFYPGRPAARLAARREWRASRLAECLLLG
ALLLWALAGGSLSLLPGSPQALADGAQGYAAAAGLLLAAAVAIKTAQLPFHGWLTQVMEAPTPISALLHAGVVNLGGMVL
IKAAPLLQAAPPANLLLMLWGGASALLCCVVMLTRISIKLRLAWSTCAQMGFMLLEIGMGWYALALLHLLAHSFYKAHAF
LLAGETARDSAARRMLGQESADGVLPHLARGLIAAALLAASQWLWQRWIPAAALPPLFWLAMGLGMGALLRGGAGWLAAL
ALSQSYLLLHALAARILPLHGPTPPEWAQALLAALFLLVFLLQGWLLRHPQGALARRIYPHAFAGFHLDEWWCMLGRRLP
RPPAPFALKWPQLRESSRD

Sequences:

>Translated_499_residues
MPQTLLAALPYAIALAWLLPALWPGRALPRHWQAAEIAALAGGLLLLPLIFLPTPAPWFAAAWLMQALIQLLGWMVLRYS
RRYMQGEPGQARFLRAIGCLLAAVTLVVQASHLLLMALAWIACSLALQTLLTFYPGRPAARLAARREWRASRLAECLLLG
ALLLWALAGGSLSLLPGSPQALADGAQGYAAAAGLLLAAAVAIKTAQLPFHGWLTQVMEAPTPISALLHAGVVNLGGMVL
IKAAPLLQAAPPANLLLMLWGGASALLCCVVMLTRISIKLRLAWSTCAQMGFMLLEIGMGWYALALLHLLAHSFYKAHAF
LLAGETARDSAARRMLGQESADGVLPHLARGLIAAALLAASQWLWQRWIPAAALPPLFWLAMGLGMGALLRGGAGWLAAL
ALSQSYLLLHALAARILPLHGPTPPEWAQALLAALFLLVFLLQGWLLRHPQGALARRIYPHAFAGFHLDEWWCMLGRRLP
RPPAPFALKWPQLRESSRD
>Mature_498_residues
PQTLLAALPYAIALAWLLPALWPGRALPRHWQAAEIAALAGGLLLLPLIFLPTPAPWFAAAWLMQALIQLLGWMVLRYSR
RYMQGEPGQARFLRAIGCLLAAVTLVVQASHLLLMALAWIACSLALQTLLTFYPGRPAARLAARREWRASRLAECLLLGA
LLLWALAGGSLSLLPGSPQALADGAQGYAAAAGLLLAAAVAIKTAQLPFHGWLTQVMEAPTPISALLHAGVVNLGGMVLI
KAAPLLQAAPPANLLLMLWGGASALLCCVVMLTRISIKLRLAWSTCAQMGFMLLEIGMGWYALALLHLLAHSFYKAHAFL
LAGETARDSAARRMLGQESADGVLPHLARGLIAAALLAASQWLWQRWIPAAALPPLFWLAMGLGMGALLRGGAGWLAALA
LSQSYLLLHALAARILPLHGPTPPEWAQALLAALFLLVFLLQGWLLRHPQGALARRIYPHAFAGFHLDEWWCMLGRRLPR
PPAPFALKWPQLRESSRD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=272, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=4e-24,
Organism=Escherichia coli, GI1788614, Length=266, Percent_Identity=33.0827067669173, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788831, Length=297, Percent_Identity=27.9461279461279, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788829, Length=286, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53850; Mature: 53719

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTLLAALPYAIALAWLLPALWPGRALPRHWQAAEIAALAGGLLLLPLIFLPTPAPWFA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AAWLMQALIQLLGWMVLRYSRRYMQGEPGQARFLRAIGCLLAAVTLVVQASHLLLMALAW
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IACSLALQTLLTFYPGRPAARLAARREWRASRLAECLLLGALLLWALAGGSLSLLPGSPQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCH
ALADGAQGYAAAAGLLLAAAVAIKTAQLPFHGWLTQVMEAPTPISALLHAGVVNLGGMVL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCE
IKAAPLLQAAPPANLLLMLWGGASALLCCVVMLTRISIKLRLAWSTCAQMGFMLLEIGMG
EEHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCH
WYALALLHLLAHSFYKAHAFLLAGETARDSAARRMLGQESADGVLPHLARGLIAAALLAA
HHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
SQWLWQRWIPAAALPPLFWLAMGLGMGALLRGGAGWLAALALSQSYLLLHALAARILPLH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPTPPEWAQALLAALFLLVFLLQGWLLRHPQGALARRIYPHAFAGFHLDEWWCMLGRRLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
RPPAPFALKWPQLRESSRD
CCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
PQTLLAALPYAIALAWLLPALWPGRALPRHWQAAEIAALAGGLLLLPLIFLPTPAPWFA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AAWLMQALIQLLGWMVLRYSRRYMQGEPGQARFLRAIGCLLAAVTLVVQASHLLLMALAW
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IACSLALQTLLTFYPGRPAARLAARREWRASRLAECLLLGALLLWALAGGSLSLLPGSPQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCH
ALADGAQGYAAAAGLLLAAAVAIKTAQLPFHGWLTQVMEAPTPISALLHAGVVNLGGMVL
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCE
IKAAPLLQAAPPANLLLMLWGGASALLCCVVMLTRISIKLRLAWSTCAQMGFMLLEIGMG
EEHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCH
WYALALLHLLAHSFYKAHAFLLAGETARDSAARRMLGQESADGVLPHLARGLIAAALLAA
HHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
SQWLWQRWIPAAALPPLFWLAMGLGMGALLRGGAGWLAALALSQSYLLLHALAARILPLH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPTPPEWAQALLAALFLLVFLLQGWLLRHPQGALARRIYPHAFAGFHLDEWWCMLGRRLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
RPPAPFALKWPQLRESSRD
CCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]