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The map label for this gene is dsbC [H]

Identifier: 34498574

GI number: 34498574

Start: 3405983

End: 3406714

Strand: Reverse

Name: dsbC [H]

Synonym: CV_3119

Alternate gene names: 34498574

Gene position: 3406714-3405983 (Counterclockwise)

Preceding gene: 34498575

Following gene: 34498573

Centisome position: 71.7

GC content: 63.11

Gene sequence:

>732_bases
ATGAACAAGAGAATGAAAACGCTGGCCCTGTCCAGCGCGATGCTGATGTCGCTGGCCGCCTGCTCCCAAGCCGCCGGCGG
CAATGTCGAGGACGTGAAGAAGGCTTTCCTGAATCACTTTCCCGGCAAGCAGGTGAAGAGCGTCAGCGCCACCCCGGTCA
AGGGCATCTACGAGCTGGTGGTGGACGGCCGCCAGGTGGTGTACGTCAACAGCGACGCCAGCTATCTGTTCGTCGGCGAC
CTGATCGACGCCAAGAACAAGGAAAGCCTGACCGAGAAGAAGATGGCCGAGCTGTCCAAGGTGGACTTCAACGCGCTGCC
GTTCCAGTACGCGTTCAAGGACGTGCGCGGCAAGGGCGAGCGCAAGATGGCGGTGTTCACCGATCCGGACTGCCCGTTCT
GCAAGAAGCTGGAGCGCGAGAGCCTGAAGGACATCGACAATGTCACCATCTACACCTTCCTCTACCCGCTGACCCAGCTG
CATCCGGACGCGATGCGCAAGTCCAAGCAGATCTGGTGCTCGGCCGACAAGGCCGCCGCCTGGACCGCCTTCATGCGCGA
CGGTAAGCCGCTGACCGGCCCGGACAACTGCGACACGCCGCTGGACAAGATCCAGGCGCTGGGCGAGAAGATGGGCATCA
CCGGCACGCCGGCGCTGGTGTTCGCCAATGGCCGCATGGTGCCGGGCGCGATCGACGGCGGCGACATCGAGCAGCTGCTG
AACGCCAAGTAA

Upstream 100 bases:

>100_bases
CGCAATACCGGCCTGTCCCTGACCAACTGCCTGACCCCGTTGAAACGGCAGTTCGCCAGGCAGGCGATTGGATACTGATA
TCCCAAAGGACCCCTGATCG

Downstream 100 bases:

>100_bases
GCCAACAGCGACGGGGCCGGTTTCATGGGTCCCGTTTTTGATGGCGGGCTGCGCGGAGCGGGGAGAGGGATGAGGCGCTG
GAACACGACCGAACGGCTGC

Product: protein disulfide-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNKRMKTLALSSAMLMSLAACSQAAGGNVEDVKKAFLNHFPGKQVKSVSATPVKGIYELVVDGRQVVYVNSDASYLFVGD
LIDAKNKESLTEKKMAELSKVDFNALPFQYAFKDVRGKGERKMAVFTDPDCPFCKKLERESLKDIDNVTIYTFLYPLTQL
HPDAMRKSKQIWCSADKAAAWTAFMRDGKPLTGPDNCDTPLDKIQALGEKMGITGTPALVFANGRMVPGAIDGGDIEQLL
NAK

Sequences:

>Translated_243_residues
MNKRMKTLALSSAMLMSLAACSQAAGGNVEDVKKAFLNHFPGKQVKSVSATPVKGIYELVVDGRQVVYVNSDASYLFVGD
LIDAKNKESLTEKKMAELSKVDFNALPFQYAFKDVRGKGERKMAVFTDPDCPFCKKLERESLKDIDNVTIYTFLYPLTQL
HPDAMRKSKQIWCSADKAAAWTAFMRDGKPLTGPDNCDTPLDKIQALGEKMGITGTPALVFANGRMVPGAIDGGDIEQLL
NAK
>Mature_243_residues
MNKRMKTLALSSAMLMSLAACSQAAGGNVEDVKKAFLNHFPGKQVKSVSATPVKGIYELVVDGRQVVYVNSDASYLFVGD
LIDAKNKESLTEKKMAELSKVDFNALPFQYAFKDVRGKGERKMAVFTDPDCPFCKKLERESLKDIDNVTIYTFLYPLTQL
HPDAMRKSKQIWCSADKAAAWTAFMRDGKPLTGPDNCDTPLDKIQALGEKMGITGTPALVFANGRMVPGAIDGGDIEQLL
NAK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=191, Percent_Identity=30.3664921465969, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26639; Mature: 26639

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRMKTLALSSAMLMSLAACSQAAGGNVEDVKKAFLNHFPGKQVKSVSATPVKGIYELV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHH
VDGRQVVYVNSDASYLFVGDLIDAKNKESLTEKKMAELSKVDFNALPFQYAFKDVRGKGE
HCCCEEEEEECCCCEEEEECHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
RKMAVFTDPDCPFCKKLERESLKDIDNVTIYTFLYPLTQLHPDAMRKSKQIWCSADKAAA
CEEEEEECCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHHCCHHHHHHHHHHEECCCCHHH
WTAFMRDGKPLTGPDNCDTPLDKIQALGEKMGITGTPALVFANGRMVPGAIDGGDIEQLL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCEECCCCCCCHHHHHHH
NAK
CCC
>Mature Secondary Structure
MNKRMKTLALSSAMLMSLAACSQAAGGNVEDVKKAFLNHFPGKQVKSVSATPVKGIYELV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHH
VDGRQVVYVNSDASYLFVGDLIDAKNKESLTEKKMAELSKVDFNALPFQYAFKDVRGKGE
HCCCEEEEEECCCCEEEEECHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCC
RKMAVFTDPDCPFCKKLERESLKDIDNVTIYTFLYPLTQLHPDAMRKSKQIWCSADKAAA
CEEEEEECCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHHCCHHHHHHHHHHEECCCCHHH
WTAFMRDGKPLTGPDNCDTPLDKIQALGEKMGITGTPALVFANGRMVPGAIDGGDIEQLL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCEECCCCCCCHHHHHHH
NAK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]