Click here to switch to the map view.

The map label for this gene is rfaE [H]

Identifier: 34498495

GI number: 34498495

Start: 3317949

End: 3318824

Strand: Reverse

Name: rfaE [H]

Synonym: CV_3040

Alternate gene names: 34498495

Gene position: 3318824-3317949 (Counterclockwise)

Preceding gene: 34498496

Following gene: 34498494

Centisome position: 69.85

GC content: 67.92

Gene sequence:

>876_bases
ATGCTGGACCGCTACTGGTTCGGCGATGTGTCGCGCATCTCTCCGGAAGCGCCGGTGCCGGTGGCCAAGATAGGCCGCAG
CGAGGAGCGCGCCGGCGGCGCCGCCAACGTGGCGCGGAACATCGCGGGCCTGGGCGGCAAGGCCACCATCCTGTCGGTGG
TGGGGGACGACGAGGCGGCGGATGCGCTGGAACGCCTGCTGGGCGACGACGGCATCGTCACTTCGTTCAAGCGCGACGCC
AACATCGCCACCACGGTGAAGTTGCGGGTGGTGGCGCGCCAGCAGCAGCTGATCCGGCTGGACTTCGAAGACGCGCCCAG
CCATGAGATCCTGGCGGACAAGCTGGAGGAGTTCACCGACATCGTCGCCGCTCACGACGTGGTGATCCTGTCCGACTACG
GCAAGGGCGGTTTGACCCACGTGGCCGAGATGATCCAGTTGGCCCGCGCCGCCGGCAAGCCGGTGCTGATCGATCCGAAG
GGCGACGATTACAGCAAGTATGCCGGCGCCACGCTGCTCACCCCCAACCGCAGCGAGTTCCGCCAGGTGGCGGGAAGCTG
GAAGGACGAGGCCAGTCTGACCGCCAAGGCCCAGGCGCTGCGCGCGGAGTTGAATCTCGATGCCTTGCTGGTGACCCGCA
GCGAGGAGGGCATGACGCTGTTCCGCGCCGACGGCGCGCTGCATCAACCCACTTTCGCGCGCGAGGTTTATGACGTGTCC
GGCGCCGGCGACACCGTGATCGGCACGCTGGGGCTGGCGTTGGCGGCCGGCCAGCCGCTGCCGGTGGCGATGAACTTGGC
CAATGCCGCCGCGGGCGTGGTGGTGGGAAAATTGGGCACCGCCGTGTGCTCGCAGCAGGAACTGTTTGCCTTGTAA

Upstream 100 bases:

>100_bases
GCTGAGGTAAGCCATGGGTCTGATGCAGAATCTGGGGCTGGAGCCCGCCGCGCTGGCCGCCAGCCTGGCCAAGGCCAAGG
TGTTGGTGGTCGGCGACGTG

Downstream 100 bases:

>100_bases
GCCGGCGCGCCGGTAGGAGACGCGATGACGAAGCTGACCGCGCAACAAGTGGAAGAGGTGCTGGCCTTCTGGTTCGACGC
CAGCGACGATGGGGCCTTGA

Product: ADP-heptose synthase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MLDRYWFGDVSRISPEAPVPVAKIGRSEERAGGAANVARNIAGLGGKATILSVVGDDEAADALERLLGDDGIVTSFKRDA
NIATTVKLRVVARQQQLIRLDFEDAPSHEILADKLEEFTDIVAAHDVVILSDYGKGGLTHVAEMIQLARAAGKPVLIDPK
GDDYSKYAGATLLTPNRSEFRQVAGSWKDEASLTAKAQALRAELNLDALLVTRSEEGMTLFRADGALHQPTFAREVYDVS
GAGDTVIGTLGLALAAGQPLPVAMNLANAAAGVVVGKLGTAVCSQQELFAL

Sequences:

>Translated_291_residues
MLDRYWFGDVSRISPEAPVPVAKIGRSEERAGGAANVARNIAGLGGKATILSVVGDDEAADALERLLGDDGIVTSFKRDA
NIATTVKLRVVARQQQLIRLDFEDAPSHEILADKLEEFTDIVAAHDVVILSDYGKGGLTHVAEMIQLARAAGKPVLIDPK
GDDYSKYAGATLLTPNRSEFRQVAGSWKDEASLTAKAQALRAELNLDALLVTRSEEGMTLFRADGALHQPTFAREVYDVS
GAGDTVIGTLGLALAAGQPLPVAMNLANAAAGVVVGKLGTAVCSQQELFAL
>Mature_291_residues
MLDRYWFGDVSRISPEAPVPVAKIGRSEERAGGAANVARNIAGLGGKATILSVVGDDEAADALERLLGDDGIVTSFKRDA
NIATTVKLRVVARQQQLIRLDFEDAPSHEILADKLEEFTDIVAAHDVVILSDYGKGGLTHVAEMIQLARAAGKPVLIDPK
GDDYSKYAGATLLTPNRSEFRQVAGSWKDEASLTAKAQALRAELNLDALLVTRSEEGMTLFRADGALHQPTFAREVYDVS
GAGDTVIGTLGLALAAGQPLPVAMNLANAAAGVVVGKLGTAVCSQQELFAL

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=296, Percent_Identity=54.7297297297297, Blast_Score=286, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 30690; Mature: 30690

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRYWFGDVSRISPEAPVPVAKIGRSEERAGGAANVARNIAGLGGKATILSVVGDDEAA
CCCCCCCCCHHHCCCCCCCCHHHCCCCHHHCCCHHHHHHHHHCCCCCEEEEEEECCCHHH
DALERLLGDDGIVTSFKRDANIATTVKLRVVARQQQLIRLDFEDAPSHEILADKLEEFTD
HHHHHHHCCCCCEEHHCCCCCEEEEEEEEEHHHHHHHEEECCCCCCCHHHHHHHHHHHHH
IVAAHDVVILSDYGKGGLTHVAEMIQLARAAGKPVLIDPKGDDYSKYAGATLLTPNRSEF
HHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHCCEEEECCCHHHH
RQVAGSWKDEASLTAKAQALRAELNLDALLVTRSEEGMTLFRADGALHQPTFAREVYDVS
HHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHCCC
GAGDTVIGTLGLALAAGQPLPVAMNLANAAAGVVVGKLGTAVCSQQELFAL
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MLDRYWFGDVSRISPEAPVPVAKIGRSEERAGGAANVARNIAGLGGKATILSVVGDDEAA
CCCCCCCCCHHHCCCCCCCCHHHCCCCHHHCCCHHHHHHHHHCCCCCEEEEEEECCCHHH
DALERLLGDDGIVTSFKRDANIATTVKLRVVARQQQLIRLDFEDAPSHEILADKLEEFTD
HHHHHHHCCCCCEEHHCCCCCEEEEEEEEEHHHHHHHEEECCCCCCCHHHHHHHHHHHHH
IVAAHDVVILSDYGKGGLTHVAEMIQLARAAGKPVLIDPKGDDYSKYAGATLLTPNRSEF
HHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHCCEEEECCCHHHH
RQVAGSWKDEASLTAKAQALRAELNLDALLVTRSEEGMTLFRADGALHQPTFAREVYDVS
HHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHCCC
GAGDTVIGTLGLALAAGQPLPVAMNLANAAAGVVVGKLGTAVCSQQELFAL
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA