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The map label for this gene is ugd [H]

Identifier: 34498496

GI number: 34498496

Start: 3318920

End: 3320239

Strand: Reverse

Name: ugd [H]

Synonym: CV_3041

Alternate gene names: 34498496

Gene position: 3320239-3318920 (Counterclockwise)

Preceding gene: 34498497

Following gene: 34498495

Centisome position: 69.88

GC content: 65.15

Gene sequence:

>1320_bases
ATGAAAGTAACGGTAATTGGCTCGGGCTATGTCGGCCTGGTGACCGGCACCTGCCTGGCCGAGACCGGCTACCACGTCTG
CTGCCTGGACGTGGATCCGCGCAAGATCGAGATTCTGCAAAGCGGCGGCATTCCCATTTTCGAGCCGGGCCTGGAAGACA
TGGTGAAGCGCAATGTGGCGGCAGGCCGCCTGCACTTCACCACCGACGTCGCCGCGTCGGTCGCCTTCGGCGACATCCAG
TTCATCGCCGTCGGCACGCCGCCGGACGAGGACGGTTCCGCCGACTTGCAATACGTGCTGGCGGCGGCGCGCAACATCGC
CCGCCACATGACCGACTACCGGGTGGTGGTGGACAAGTCCACTGTGCCGGTGGGCACGGCGGACAAGGTGCGCGCCGCCA
TCGCCGACGAGCTGGCGGCGCGCGGCGCCGACATTCCGTTCAGCGTGGTGTCCAATCCGGAATTCCTGAAGGAAGGCGCG
GCGATCGATGACTTCATGCGGCCCGACCGCGTGGTGATCGGCGCCGACGACGACCGCGCGGCCGAGATCATGCGCCGCCT
GTACAAACCGTTCCAGCGCAGCCATGAGCGCGTGCTGCTGATGGATGTGCGCTCGGCGGAACTGACCAAGTACGCGGCCA
ACGCGATGCTGGCCACCCGCATCTCGTTCATGAACGAGCTGGCCAATTTGGCCGAAACCATGGGCGCGGACATCGAACAG
GTGCGCCAGGGCATGGGTTCCGATCCGCGCATCGGCTACCATTTCCTGTATCCGGGCGTAGGCTACGGCGGCTCCTGCTT
CCCCAAGGACGTCAAGGCGCTGGTGCAGACCGCCAAGGAAAACGGCCACACGCTGCGCGTGCTGACCGCAGTGGAAGAGG
CCAACGAGGTCCAGAAGCTGCGCCTGGTCGAAAAAGTGGTTTCCCGTTTCGGCGAAGATCTGTCCGGCCGCCGTTTCGCG
TTGTGGGGCCTGGCGTTCAAACCCAATACCGATGATATGCGCGAAGCGCCCAGCCGCGTGATCGTCGAGGAACTGACCCG
CCGCGGCGCCGAGATCGTCGCTTTCGACCCGGTGGCCGCCCACGAGGCGCAGCGGGTGATGACAGGGGTCAACGGCATCG
CGTTCGCCGAAGACATGATGAAGGCGCTGCAGGACGCGGACGCGCTGCTGATCGTCACCGAATGGAAGATGTTCCGCGCG
CCGGATTTCGAGGCGGTCCGCCGCAGTCTGAAGCAACCGCTGATTTTCGACGGCCGCAATATGTACGATCCGGCGTGGCT
GCGCGAGCAGGGCTTCGATTACCACGCCATCGGCCGCTGA

Upstream 100 bases:

>100_bases
ACTATCTGGTGATCGGCCGGCCGATCACCCGCGCCGCGGACCCGTTGGCCGCGCTGCGCGCCATCAATCAAGACATTTCC
GTATTCCTGGGTAAACAATC

Downstream 100 bases:

>100_bases
GGTAAGCCATGGGTCTGATGCAGAATCTGGGGCTGGAGCCCGCCGCGCTGGCCGCCAGCCTGGCCAAGGCCAAGGTGTTG
GTGGTCGGCGACGTGATGCT

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKVTVIGSGYVGLVTGTCLAETGYHVCCLDVDPRKIEILQSGGIPIFEPGLEDMVKRNVAAGRLHFTTDVAASVAFGDIQ
FIAVGTPPDEDGSADLQYVLAAARNIARHMTDYRVVVDKSTVPVGTADKVRAAIADELAARGADIPFSVVSNPEFLKEGA
AIDDFMRPDRVVIGADDDRAAEIMRRLYKPFQRSHERVLLMDVRSAELTKYAANAMLATRISFMNELANLAETMGADIEQ
VRQGMGSDPRIGYHFLYPGVGYGGSCFPKDVKALVQTAKENGHTLRVLTAVEEANEVQKLRLVEKVVSRFGEDLSGRRFA
LWGLAFKPNTDDMREAPSRVIVEELTRRGAEIVAFDPVAAHEAQRVMTGVNGIAFAEDMMKALQDADALLIVTEWKMFRA
PDFEAVRRSLKQPLIFDGRNMYDPAWLREQGFDYHAIGR

Sequences:

>Translated_439_residues
MKVTVIGSGYVGLVTGTCLAETGYHVCCLDVDPRKIEILQSGGIPIFEPGLEDMVKRNVAAGRLHFTTDVAASVAFGDIQ
FIAVGTPPDEDGSADLQYVLAAARNIARHMTDYRVVVDKSTVPVGTADKVRAAIADELAARGADIPFSVVSNPEFLKEGA
AIDDFMRPDRVVIGADDDRAAEIMRRLYKPFQRSHERVLLMDVRSAELTKYAANAMLATRISFMNELANLAETMGADIEQ
VRQGMGSDPRIGYHFLYPGVGYGGSCFPKDVKALVQTAKENGHTLRVLTAVEEANEVQKLRLVEKVVSRFGEDLSGRRFA
LWGLAFKPNTDDMREAPSRVIVEELTRRGAEIVAFDPVAAHEAQRVMTGVNGIAFAEDMMKALQDADALLIVTEWKMFRA
PDFEAVRRSLKQPLIFDGRNMYDPAWLREQGFDYHAIGR
>Mature_439_residues
MKVTVIGSGYVGLVTGTCLAETGYHVCCLDVDPRKIEILQSGGIPIFEPGLEDMVKRNVAAGRLHFTTDVAASVAFGDIQ
FIAVGTPPDEDGSADLQYVLAAARNIARHMTDYRVVVDKSTVPVGTADKVRAAIADELAARGADIPFSVVSNPEFLKEGA
AIDDFMRPDRVVIGADDDRAAEIMRRLYKPFQRSHERVLLMDVRSAELTKYAANAMLATRISFMNELANLAETMGADIEQ
VRQGMGSDPRIGYHFLYPGVGYGGSCFPKDVKALVQTAKENGHTLRVLTAVEEANEVQKLRLVEKVVSRFGEDLSGRRFA
LWGLAFKPNTDDMREAPSRVIVEELTRRGAEIVAFDPVAAHEAQRVMTGVNGIAFAEDMMKALQDADALLIVTEWKMFRA
PDFEAVRRSLKQPLIFDGRNMYDPAWLREQGFDYHAIGR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=468, Percent_Identity=35.2564102564103, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=36.3387978142077, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI296040443, Length=321, Percent_Identity=36.4485981308411, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1788340, Length=366, Percent_Identity=29.7814207650273, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI48994968, Length=441, Percent_Identity=27.891156462585, Blast_Score=148, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17560350, Length=466, Percent_Identity=33.9055793991416, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI17136908, Length=469, Percent_Identity=36.0341151385927, Blast_Score=255, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48375; Mature: 48375

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTVIGSGYVGLVTGTCLAETGYHVCCLDVDPRKIEILQSGGIPIFEPGLEDMVKRNVA
CEEEEEECCCEEHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEECCCHHHHHHCCCC
AGRLHFTTDVAASVAFGDIQFIAVGTPPDEDGSADLQYVLAAARNIARHMTDYRVVVDKS
CCEEEEEHHHHHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECC
TVPVGTADKVRAAIADELAARGADIPFSVVSNPEFLKEGAAIDDFMRPDRVVIGADDDRA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
AEIMRRLYKPFQRSHERVLLMDVRSAELTKYAANAMLATRISFMNELANLAETMGADIEQ
HHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGMGSDPRIGYHFLYPGVGYGGSCFPKDVKALVQTAKENGHTLRVLTAVEEANEVQKL
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
RLVEKVVSRFGEDLSGRRFALWGLAFKPNTDDMREAPSRVIVEELTRRGAEIVAFDPVAA
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHH
HEAQRVMTGVNGIAFAEDMMKALQDADALLIVTEWKMFRAPDFEAVRRSLKQPLIFDGRN
HHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCHHHCCCCHHHHHHHHCCCEEECCCC
MYDPAWLREQGFDYHAIGR
CCCCHHHHHCCCCEECCCC
>Mature Secondary Structure
MKVTVIGSGYVGLVTGTCLAETGYHVCCLDVDPRKIEILQSGGIPIFEPGLEDMVKRNVA
CEEEEEECCCEEHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEECCCHHHHHHCCCC
AGRLHFTTDVAASVAFGDIQFIAVGTPPDEDGSADLQYVLAAARNIARHMTDYRVVVDKS
CCEEEEEHHHHHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECC
TVPVGTADKVRAAIADELAARGADIPFSVVSNPEFLKEGAAIDDFMRPDRVVIGADDDRA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEECCCHHH
AEIMRRLYKPFQRSHERVLLMDVRSAELTKYAANAMLATRISFMNELANLAETMGADIEQ
HHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRQGMGSDPRIGYHFLYPGVGYGGSCFPKDVKALVQTAKENGHTLRVLTAVEEANEVQKL
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
RLVEKVVSRFGEDLSGRRFALWGLAFKPNTDDMREAPSRVIVEELTRRGAEIVAFDPVAA
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHH
HEAQRVMTGVNGIAFAEDMMKALQDADALLIVTEWKMFRAPDFEAVRRSLKQPLIFDGRN
HHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCHHHCCCCHHHHHHHHCCCEEECCCC
MYDPAWLREQGFDYHAIGR
CCCCHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]