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The map label for this gene is caiB [H]

Identifier: 34498468

GI number: 34498468

Start: 3289455

End: 3290849

Strand: Direct

Name: caiB [H]

Synonym: CV_3013

Alternate gene names: 34498468

Gene position: 3289455-3290849 (Clockwise)

Preceding gene: 34498467

Following gene: 34498469

Centisome position: 69.24

GC content: 72.83

Gene sequence:

>1395_bases
ATGCCCGCGCTCGCCCTTCGCGCAGTCCGCCAGCTCTGGCTCGACTGCGGCCTCGACGCCTCCGCCCTCTCCCAGCTTGA
ACTGAACGACGGCGGCGCCATGCTGCCTTCTTCCTTCGCCATCGCCGCCGCCGCGCAGGCGTCGATAGGCGCTTGCGGAT
TGGCGGCGGCTGAATTCTGGCGTCTGCGCGGCGGGGAGCTGCAGACGGTCGGCGTCGACGCCAGCCATGCCGTCGCGGAA
TTCCGCAGCGAGCACTATTTCCGCGTCGATGGCGCGCTCCCGGCCGACCCCTGGGACAAGATAGCCGGCATCTATCGCTG
CGGAGACGGACGCTGGGTGCGCATCCACACCAACTTCGCCCATCACTGCCGGGGCGTGCTGGATCTATTGGGCTGCGAAT
ACGACAGGGATGCGGTGGCCGGCGCGCTGGCGACCTGGTCCGCCTTCGATTTCGAGGACGCGGCCGCAGAGCGCGGCCTG
GTCGTCGCCGCGCTGCGCAGCTTCGCCGAATGGGATGCGCATCCGCAAGGCCGCGCCGTCGCCGCACTGCCGCCGCTGAC
CATCACGCGGATAGGAGACGCGCCGCCCTTGCCGCTCCCGCCCTCTTTCCGTCCGCTGCAAGGCATCCGCGCGCTGGACC
TGACCCGCATCATCGCCGGCCCGGTGGCCGGACGCGCGCTGGCCGCCCACGGCGCCGACGTACTGCGCATCACCTCGCCG
AACCTGCCCACCATAGCGACGCTCGATATCGACACCGGACGCGGCAAGCGCAACGCCGGGCTGGACCTGACGACGGCAGC
GGGCCGCGAGGCGCTGCGCGCCCTGCTGGCCGACGCCCATGTCTTCATCCAGGGCTACCGGCCGGGAGGCTTGGCCGCGC
TGGGTTTCTCTCCCGAGGATGCCGCGCGCCTCCGCCCCGGCATCGTCTACGTTTCGCTCAGCGCCTACGGCCATACTGGC
CCCTGGGCTGGGCGCCGAGGCTTCGACTCGCTGACCCAGGCCGCCAGCGGCTTCAACCTGGCCGAAGCCGAGGCCGCCGG
CAGCGATGCGCCCCGCGCGCTGCCGGCCCAGGCGCTGGACCACGGCGCCGGCTACCTGGCGGCGCTGGGCGCGATCGCCG
CGCTGCACCGCCAGCGGGCCGAGGGCGGCAGCTGGCACGTGCAGGTGTCGCTGGCCCAGACCGGCCATTGGCTGCGCGGC
CTGGGCCGGGTGGCCGGCGCGATGGATCGGTCCTTGCCGACGCTGGACGATGTCCGCCCCTGGCTGGAAGAGCGCGACTC
CGGCTTCGGTCGCCTGCTGGCGGTGCGCCACGCCGCCCGAATGGCGCTGACGCCGGCGCGCTGGGACCTGCCGTCGATGC
CGCTGGACAGCCACGTCCCAGGCTGGGCTGGCTGA

Upstream 100 bases:

>100_bases
GCGCGACTTCCTGGCCGGAGACGCCCCCCAATAAGGACATATGCATTGACCGGCAGGAAAGCGCGGGTTGTAATGCGATA
TCCACCATCCGGGGAAACCC

Downstream 100 bases:

>100_bases
AAAGACAGGTTTCACCGCAGCCGGCCTCGCTAAAACTGGCAGTTTCGATACTCGTCGAGGCAGGGATGAAAACCAACAAG
TACCTGATCGAAGCGCTGCT

Product: carnitine dehydratase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MPALALRAVRQLWLDCGLDASALSQLELNDGGAMLPSSFAIAAAAQASIGACGLAAAEFWRLRGGELQTVGVDASHAVAE
FRSEHYFRVDGALPADPWDKIAGIYRCGDGRWVRIHTNFAHHCRGVLDLLGCEYDRDAVAGALATWSAFDFEDAAAERGL
VVAALRSFAEWDAHPQGRAVAALPPLTITRIGDAPPLPLPPSFRPLQGIRALDLTRIIAGPVAGRALAAHGADVLRITSP
NLPTIATLDIDTGRGKRNAGLDLTTAAGREALRALLADAHVFIQGYRPGGLAALGFSPEDAARLRPGIVYVSLSAYGHTG
PWAGRRGFDSLTQAASGFNLAEAEAAGSDAPRALPAQALDHGAGYLAALGAIAALHRQRAEGGSWHVQVSLAQTGHWLRG
LGRVAGAMDRSLPTLDDVRPWLEERDSGFGRLLAVRHAARMALTPARWDLPSMPLDSHVPGWAG

Sequences:

>Translated_464_residues
MPALALRAVRQLWLDCGLDASALSQLELNDGGAMLPSSFAIAAAAQASIGACGLAAAEFWRLRGGELQTVGVDASHAVAE
FRSEHYFRVDGALPADPWDKIAGIYRCGDGRWVRIHTNFAHHCRGVLDLLGCEYDRDAVAGALATWSAFDFEDAAAERGL
VVAALRSFAEWDAHPQGRAVAALPPLTITRIGDAPPLPLPPSFRPLQGIRALDLTRIIAGPVAGRALAAHGADVLRITSP
NLPTIATLDIDTGRGKRNAGLDLTTAAGREALRALLADAHVFIQGYRPGGLAALGFSPEDAARLRPGIVYVSLSAYGHTG
PWAGRRGFDSLTQAASGFNLAEAEAAGSDAPRALPAQALDHGAGYLAALGAIAALHRQRAEGGSWHVQVSLAQTGHWLRG
LGRVAGAMDRSLPTLDDVRPWLEERDSGFGRLLAVRHAARMALTPARWDLPSMPLDSHVPGWAG
>Mature_463_residues
PALALRAVRQLWLDCGLDASALSQLELNDGGAMLPSSFAIAAAAQASIGACGLAAAEFWRLRGGELQTVGVDASHAVAEF
RSEHYFRVDGALPADPWDKIAGIYRCGDGRWVRIHTNFAHHCRGVLDLLGCEYDRDAVAGALATWSAFDFEDAAAERGLV
VAALRSFAEWDAHPQGRAVAALPPLTITRIGDAPPLPLPPSFRPLQGIRALDLTRIIAGPVAGRALAAHGADVLRITSPN
LPTIATLDIDTGRGKRNAGLDLTTAAGREALRALLADAHVFIQGYRPGGLAALGFSPEDAARLRPGIVYVSLSAYGHTGP
WAGRRGFDSLTQAASGFNLAEAEAAGSDAPRALPAQALDHGAGYLAALGAIAALHRQRAEGGSWHVQVSLAQTGHWLRGL
GRVAGAMDRSLPTLDDVRPWLEERDSGFGRLLAVRHAARMALTPARWDLPSMPLDSHVPGWAG

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863124, Length=195, Percent_Identity=32.3076923076923, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI300863128, Length=195, Percent_Identity=32.3076923076923, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI300863126, Length=149, Percent_Identity=32.8859060402685, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI42794625, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI266456254, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI266458397, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI266458393, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI42822893, Length=133, Percent_Identity=33.8345864661654, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI266458395, Length=133, Percent_Identity=33.8345864661654, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788717, Length=145, Percent_Identity=28.9655172413793, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082093, Length=200, Percent_Identity=28, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786222, Length=211, Percent_Identity=27.9620853080569, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115535051, Length=183, Percent_Identity=31.1475409836066, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32564160, Length=185, Percent_Identity=30.2702702702703, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24648431, Length=195, Percent_Identity=30.2564102564103, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24585488, Length=190, Percent_Identity=30, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 48934; Mature: 48803

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALALRAVRQLWLDCGLDASALSQLELNDGGAMLPSSFAIAAAAQASIGACGLAAAEFW
CCHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
RLRGGELQTVGVDASHAVAEFRSEHYFRVDGALPADPWDKIAGIYRCGDGRWVRIHTNFA
HHCCCEEEEECCCHHHHHHHHHCCCEEEECCCCCCCHHHHHCEEEEECCCCEEEEECCHH
HHCRGVLDLLGCEYDRDAVAGALATWSAFDFEDAAAERGLVVAALRSFAEWDAHPQGRAV
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCEE
AALPPLTITRIGDAPPLPLPPSFRPLQGIRALDLTRIIAGPVAGRALAAHGADVLRITSP
EECCCEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCHHHHCCCCEEEEECC
NLPTIATLDIDTGRGKRNAGLDLTTAAGREALRALLADAHVFIQGYRPGGLAALGFSPED
CCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCH
AARLRPGIVYVSLSAYGHTGPWAGRRGFDSLTQAASGFNLAEAEAAGSDAPRALPAQALD
HHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHH
HGAGYLAALGAIAALHRQRAEGGSWHVQVSLAQTGHWLRGLGRVAGAMDRSLPTLDDVRP
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHHHHHHHHHHHHCCCCCHHHHHH
WLEERDSGFGRLLAVRHAARMALTPARWDLPSMPLDSHVPGWAG
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PALALRAVRQLWLDCGLDASALSQLELNDGGAMLPSSFAIAAAAQASIGACGLAAAEFW
CHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
RLRGGELQTVGVDASHAVAEFRSEHYFRVDGALPADPWDKIAGIYRCGDGRWVRIHTNFA
HHCCCEEEEECCCHHHHHHHHHCCCEEEECCCCCCCHHHHHCEEEEECCCCEEEEECCHH
HHCRGVLDLLGCEYDRDAVAGALATWSAFDFEDAAAERGLVVAALRSFAEWDAHPQGRAV
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCEE
AALPPLTITRIGDAPPLPLPPSFRPLQGIRALDLTRIIAGPVAGRALAAHGADVLRITSP
EECCCEEEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCHHHHCCCCEEEEECC
NLPTIATLDIDTGRGKRNAGLDLTTAAGREALRALLADAHVFIQGYRPGGLAALGFSPED
CCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCH
AARLRPGIVYVSLSAYGHTGPWAGRRGFDSLTQAASGFNLAEAEAAGSDAPRALPAQALD
HHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHH
HGAGYLAALGAIAALHRQRAEGGSWHVQVSLAQTGHWLRGLGRVAGAMDRSLPTLDDVRP
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHHHHHHHHHHHHCCCCCHHHHHH
WLEERDSGFGRLLAVRHAARMALTPARWDLPSMPLDSHVPGWAG
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]