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The map label for this gene is ppiD [C]

Identifier: 34498387

GI number: 34498387

Start: 3209188

End: 3209976

Strand: Direct

Name: ppiD [C]

Synonym: CV_2932

Alternate gene names: 34498387

Gene position: 3209188-3209976 (Clockwise)

Preceding gene: 34498386

Following gene: 34498388

Centisome position: 67.55

GC content: 65.02

Gene sequence:

>789_bases
ATGAAACTCTCCCGTATCGCCGCCCTGACGCTGGCAGCCTCGATCAGCCTGCCGGTCGCCGCGGAGTCGATCGCCGTGGT
CAACGGCGTCTCCATCGACAAGTCCGAACTGGACGCCGCCGTCACCAATGTCGTGCAAAGCAGCGGCGGCAAGATGCAGG
ACAGCCCCGAACTGCGCGAGCAGTTGAAGAACTCGCTGATCGGCCGCCAGCTGATCCTGCAGGAGTCCACCCGCCGCGGC
CTGGACAAGCAGCCGGCCTTCGCGAAGCGGATGGATGAAGTCCGCGCCGAGCTGCTGCGCGACGCGCTGTTCGCCGACAT
CGCGGAGAAAGCCAACGTAGGCGACGCCCAGATCAAGGCCCGCTACGACGAAATGGCCGCGCAGGTCGCCGGCAGCAAGG
AAGTCCATGCCTACCAGATCACGCTCGGCAGCGAAGCCGACGCGCAGAAGGTGATCGCCCAGCTGAAGAAGGGCGCCAAG
TTCGACGAACTGGTCAAGACCCGCTCCATCGACCCCAACGCCAAGCAAAGCGGCGGCGACATGAACTGGGGCAACCTGTC
CCGCATGGAGCCCAAGCTGGCCGAGGCGCTGAAAGCCATCCCCAAGGGCCAGGTCAGCAGCGCGCCTTACCAGTCCCAAC
TGGGCTGGCACGTATTCAAGGTAGCCGACATCCGCAACGCCCAGGTGCCGCCGCTGGACGCCGTCAAGCCGCAGATCGCC
CGCCAGTTGCAGGAAGAAGCCATTGCCAAGGCCGTGGAAGACCTGCGCGCCAAGAGCAAGATCCAGTAA

Upstream 100 bases:

>100_bases
TCTACCAGACCCTGGGCGAGATGATGTCCGGCCGCGTCCACGCGCTGGCCATCCGCGCCCTGACACCAGAAGAACTCTGA
ATTTCTACCAAAGGGACAAT

Downstream 100 bases:

>100_bases
ATCCACCTTATCCGGGAATAGAACAACATGCGTAAAATCCTGCTGCAAACCGCCCTGGTAGCCGCTTTCGCCGGCAGCGC
GATCGCCGTGGCCGGCCCGT

Product: signal peptide protein

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKLSRIAALTLAASISLPVAAESIAVVNGVSIDKSELDAAVTNVVQSSGGKMQDSPELREQLKNSLIGRQLILQESTRRG
LDKQPAFAKRMDEVRAELLRDALFADIAEKANVGDAQIKARYDEMAAQVAGSKEVHAYQITLGSEADAQKVIAQLKKGAK
FDELVKTRSIDPNAKQSGGDMNWGNLSRMEPKLAEALKAIPKGQVSSAPYQSQLGWHVFKVADIRNAQVPPLDAVKPQIA
RQLQEEAIAKAVEDLRAKSKIQ

Sequences:

>Translated_262_residues
MKLSRIAALTLAASISLPVAAESIAVVNGVSIDKSELDAAVTNVVQSSGGKMQDSPELREQLKNSLIGRQLILQESTRRG
LDKQPAFAKRMDEVRAELLRDALFADIAEKANVGDAQIKARYDEMAAQVAGSKEVHAYQITLGSEADAQKVIAQLKKGAK
FDELVKTRSIDPNAKQSGGDMNWGNLSRMEPKLAEALKAIPKGQVSSAPYQSQLGWHVFKVADIRNAQVPPLDAVKPQIA
RQLQEEAIAKAVEDLRAKSKIQ
>Mature_262_residues
MKLSRIAALTLAASISLPVAAESIAVVNGVSIDKSELDAAVTNVVQSSGGKMQDSPELREQLKNSLIGRQLILQESTRRG
LDKQPAFAKRMDEVRAELLRDALFADIAEKANVGDAQIKARYDEMAAQVAGSKEVHAYQITLGSEADAQKVIAQLKKGAK
FDELVKTRSIDPNAKQSGGDMNWGNLSRMEPKLAEALKAIPKGQVSSAPYQSQLGWHVFKVADIRNAQVPPLDAVKPQIA
RQLQEEAIAKAVEDLRAKSKIQ

Specific function: Ppiases Accelerate The Folding Of Proteins. Seems To Be Involved In The Folding Of Outer Membrane Proteins. Its Preference At The P1 Position Of The Peptide Substrate Is Glu > Leu > Ala > His > Val > Phe > Ile > Gly > Lys > Thr. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Type II Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28376; Mature: 28376

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSRIAALTLAASISLPVAAESIAVVNGVSIDKSELDAAVTNVVQSSGGKMQDSPELRE
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
QLKNSLIGRQLILQESTRRGLDKQPAFAKRMDEVRAELLRDALFADIAEKANVGDAQIKA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RYDEMAAQVAGSKEVHAYQITLGSEADAQKVIAQLKKGAKFDELVKTRSIDPNAKQSGGD
HHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCC
MNWGNLSRMEPKLAEALKAIPKGQVSSAPYQSQLGWHVFKVADIRNAQVPPLDAVKPQIA
CCCCCCHHCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCHHCCHHHH
RQLQEEAIAKAVEDLRAKSKIQ
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLSRIAALTLAASISLPVAAESIAVVNGVSIDKSELDAAVTNVVQSSGGKMQDSPELRE
CCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
QLKNSLIGRQLILQESTRRGLDKQPAFAKRMDEVRAELLRDALFADIAEKANVGDAQIKA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RYDEMAAQVAGSKEVHAYQITLGSEADAQKVIAQLKKGAKFDELVKTRSIDPNAKQSGGD
HHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCC
MNWGNLSRMEPKLAEALKAIPKGQVSSAPYQSQLGWHVFKVADIRNAQVPPLDAVKPQIA
CCCCCCHHCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCHHCCHHHH
RQLQEEAIAKAVEDLRAKSKIQ
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]