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The map label for this gene is surA [C]

Identifier: 34498388

GI number: 34498388

Start: 3210004

End: 3210786

Strand: Direct

Name: surA [C]

Synonym: CV_2933

Alternate gene names: 34498388

Gene position: 3210004-3210786 (Clockwise)

Preceding gene: 34498387

Following gene: 34498389

Centisome position: 67.56

GC content: 62.96

Gene sequence:

>783_bases
ATGCGTAAAATCCTGCTGCAAACCGCCCTGGTAGCCGCTTTCGCCGGCAGCGCGATCGCCGTGGCCGGCCCGTCCGTCAA
CGGCCAGCCCATCTCCGACGCCCGCGTCGACGCCGTGGTGAAAATGATGGAAGCCCAGGGTCAGAACGTGAACCCGCAGG
CCCGCGACCAGATCAAGGACCAACTGGTGACCGCCGAAGTGCTGCGCCAGGAAGCCGTGAAGAAGGGCCTGGACAAGTCG
CCGGAATTCAACGCCGAACTGCAGAACATGCAGGCGATGGCGCTGGCCAACCGCCTGATCAAGGACTACGAGAAGGCTAA
TCCGCTGAGCGAGGCCGATCTGAAGGCCGAATACGACAAGCTGGCGGCCTCGGTGCCGGAAACCAAGCAGTTCCACGCCC
GCCACATCCTGGTTAAGAGCGAAGCCGAAGCCAAGTCCGTGATCGACGCGCTGAAGAAGGGCAAGTCCTTCGACAAGCTG
GCCAAGGAAAAATCGCAGGATCCGGGCAGCAAGGCCAATGGCGGCGACCTGGGCTGGCAAGAAGCCGGCACTTTCGTCGC
GCCGTTCTCCGAAGCGATGAGCAAGCTCGCCAAGGGCGAAGTGACCGCCAAGCCGGTGAAGACCGAATACGGCTGGCACG
TGATCAAGCTGGACGACGTGCGCACCCAGCGCAACGTGCCGCAGCTCGAGGAAATCCGTCCGCAGCTGACCCAGCGCGTG
ATGGGCGCCCGCATCGAGAAATATGTCGCCGAGCTGAAGGCCAAGGCGCAGATCCAGCAGTAA

Upstream 100 bases:

>100_bases
CGCCCGCCAGTTGCAGGAAGAAGCCATTGCCAAGGCCGTGGAAGACCTGCGCGCCAAGAGCAAGATCCAGTAAATCCACC
TTATCCGGGAATAGAACAAC

Downstream 100 bases:

>100_bases
GCCCCCGCACCGCGCGCGACGGGGACGGCTTGCCGTCCCCGTTTTGCTTGACAGCGCTCCCCGCCGCGCTTACCTTCCCG
CTCATCCGCAGCAGGCCCGC

Product: signal peptide protein

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MRKILLQTALVAAFAGSAIAVAGPSVNGQPISDARVDAVVKMMEAQGQNVNPQARDQIKDQLVTAEVLRQEAVKKGLDKS
PEFNAELQNMQAMALANRLIKDYEKANPLSEADLKAEYDKLAASVPETKQFHARHILVKSEAEAKSVIDALKKGKSFDKL
AKEKSQDPGSKANGGDLGWQEAGTFVAPFSEAMSKLAKGEVTAKPVKTEYGWHVIKLDDVRTQRNVPQLEEIRPQLTQRV
MGARIEKYVAELKAKAQIQQ

Sequences:

>Translated_260_residues
MRKILLQTALVAAFAGSAIAVAGPSVNGQPISDARVDAVVKMMEAQGQNVNPQARDQIKDQLVTAEVLRQEAVKKGLDKS
PEFNAELQNMQAMALANRLIKDYEKANPLSEADLKAEYDKLAASVPETKQFHARHILVKSEAEAKSVIDALKKGKSFDKL
AKEKSQDPGSKANGGDLGWQEAGTFVAPFSEAMSKLAKGEVTAKPVKTEYGWHVIKLDDVRTQRNVPQLEEIRPQLTQRV
MGARIEKYVAELKAKAQIQQ
>Mature_260_residues
MRKILLQTALVAAFAGSAIAVAGPSVNGQPISDARVDAVVKMMEAQGQNVNPQARDQIKDQLVTAEVLRQEAVKKGLDKS
PEFNAELQNMQAMALANRLIKDYEKANPLSEADLKAEYDKLAASVPETKQFHARHILVKSEAEAKSVIDALKKGKSFDKL
AKEKSQDPGSKANGGDLGWQEAGTFVAPFSEAMSKLAKGEVTAKPVKTEYGWHVIKLDDVRTQRNVPQLEEIRPQLTQRV
MGARIEKYVAELKAKAQIQQ

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=120, Percent_Identity=37.5, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786645, Length=133, Percent_Identity=36.0902255639098, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537235, Length=90, Percent_Identity=37.7777777777778, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28487; Mature: 28487

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKILLQTALVAAFAGSAIAVAGPSVNGQPISDARVDAVVKMMEAQGQNVNPQARDQIKD
CHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QLVTAEVLRQEAVKKGLDKSPEFNAELQNMQAMALANRLIKDYEKANPLSEADLKAEYDK
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LAASVPETKQFHARHILVKSEAEAKSVIDALKKGKSFDKLAKEKSQDPGSKANGGDLGWQ
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHH
EAGTFVAPFSEAMSKLAKGEVTAKPVKTEYGWHVIKLDDVRTQRNVPQLEEIRPQLTQRV
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHH
MGARIEKYVAELKAKAQIQQ
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKILLQTALVAAFAGSAIAVAGPSVNGQPISDARVDAVVKMMEAQGQNVNPQARDQIKD
CHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QLVTAEVLRQEAVKKGLDKSPEFNAELQNMQAMALANRLIKDYEKANPLSEADLKAEYDK
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LAASVPETKQFHARHILVKSEAEAKSVIDALKKGKSFDKLAKEKSQDPGSKANGGDLGWQ
HHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHH
EAGTFVAPFSEAMSKLAKGEVTAKPVKTEYGWHVIKLDDVRTQRNVPQLEEIRPQLTQRV
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHH
MGARIEKYVAELKAKAQIQQ
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]