BacMap

Definition	Chromobacterium violaceum ATCC 12472 chromosome, complete genome.
Accession	NC_005085
Length	4,751,080

Click here to switch to the map view.

The map label for this gene is fabG [C]

Identifier: 34498162

GI number: 34498162

Start: 2930934

End: 2931692

Strand: Direct

Name: fabG [C]

Synonym: CV_2707

Alternate gene names: 34498162

Gene position: 2930934-2931692 (Clockwise)

Preceding gene: 34498155

Following gene: 34498163

Centisome position: 61.69

GC content: 68.51

Gene sequence:

>759_bases
ATGAGCCAAGCCAATCTTGCAGGACAAGTCGCACTGATCATCGGCGCATCGCGCAATATGGGCCGCGCCTTCGCCGCAGC
GCTGGCCGCGGACGGCGCCGCCGTCGCCATCCACTACCACAGCGCCGGCTCCCGCGCCGGGGCGGAAGAAGCCGCCGCCG
CGATCCTGGCCGCCGGCGGCCAGGCCTTCGCGGTGCAGGCCGACGTCACCAAGGTGGCGGAAGTGCGCCGCCTGTTCGAC
GCGGTGGAGGAGCGCTTCGGCCATCTGGACATCCTGATCAACACCGCCGGCATGATGGTGAAGAAGGCGATCACCGAGGT
CAGCGAGGAAGAATTCGACGCCATCTTCGCGCTGAACACCAAGGCCGCGTTCTTCGCGCTGCAGGAAGCCGGCCGCCGCA
TCCGCGACAACGGCCGCATCGTCAGCGTCGGCACCTCGCTGCTGGCCGCCACCACCGGCCACTACGGCGCCTACGCCGGC
AGCAAGGCGCCGCTGGAGGACTTCACCCGCGCGCTGGCCAAGGAAATCGGCCACCGCGGCGTCACCGTCAACGTGGTCGC
CCCCGGCCCGATGGATACGGAATTCTTCTACGCCGCGGAAACACCGGAAGCCGTCGCCTACCTGAAGCGCGCCAGCATCA
ACGGCGAGCTGGGCCAGGTGGCCGACCTGGTGCCGCTGGTCAAGCATCTGGTCTCGCCGGAAAACCGCTGGACCACCGCG
CAGACCCTCTTCATCAACGGCGGCTTCGTGTCCCGCTAA

Upstream 100 bases:

>100_bases
TGTAAACAATAAAGCGCCGTTTATCCGGATTAAACCCGGCAATACACTGCAAAGCGTCAACTGCAGGCCGCGCCAGCGGC
GAACCCAACGGAGAACTGAT

Downstream 100 bases:

>100_bases
GCCATCGCCATACCGGCAAGGCCGCCCACACGGCGGCCTTTTCTCGCCGCGCGAGAAGCGGCGCGCCTATCCATTTCATC
TGGCATCCAAGTTTGGGCAA

Product: short chain dehydrogenase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSQANLAGQVALIIGASRNMGRAFAAALAADGAAVAIHYHSAGSRAGAEEAAAAILAAGGQAFAVQADVTKVAEVRRLFD
AVEERFGHLDILINTAGMMVKKAITEVSEEEFDAIFALNTKAAFFALQEAGRRIRDNGRIVSVGTSLLAATTGHYGAYAG
SKAPLEDFTRALAKEIGHRGVTVNVVAPGPMDTEFFYAAETPEAVAYLKRASINGELGQVADLVPLVKHLVSPENRWTTA
QTLFINGGFVSR

Sequences:

>Translated_252_residues
MSQANLAGQVALIIGASRNMGRAFAAALAADGAAVAIHYHSAGSRAGAEEAAAAILAAGGQAFAVQADVTKVAEVRRLFD
AVEERFGHLDILINTAGMMVKKAITEVSEEEFDAIFALNTKAAFFALQEAGRRIRDNGRIVSVGTSLLAATTGHYGAYAG
SKAPLEDFTRALAKEIGHRGVTVNVVAPGPMDTEFFYAAETPEAVAYLKRASINGELGQVADLVPLVKHLVSPENRWTTA
QTLFINGGFVSR
>Mature_251_residues
SQANLAGQVALIIGASRNMGRAFAAALAADGAAVAIHYHSAGSRAGAEEAAAAILAAGGQAFAVQADVTKVAEVRRLFDA
VEERFGHLDILINTAGMMVKKAITEVSEEEFDAIFALNTKAAFFALQEAGRRIRDNGRIVSVGTSLLAATTGHYGAYAGS
KAPLEDFTRALAKEIGHRGVTVNVVAPGPMDTEFFYAAETPEAVAYLKRASINGELGQVADLVPLVKHLVSPENRWTTAQ
TLFINGGFVSR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=29.5081967213115, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=27.5590551181102, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=28.1124497991968, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=30, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=26.8199233716475, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI4504505, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=33.6032388663968, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=29.7959183673469, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=29.0322580645161, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=32.3886639676113, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=28.8, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=28.1853281853282, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=27.734375, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=27.710843373494, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=29.718875502008, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=28.2352941176471, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789057, Length=269, Percent_Identity=25.6505576208178, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786812, Length=133, Percent_Identity=36.0902255639098, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=28.0632411067194, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=31.5789473684211, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=239, Percent_Identity=32.2175732217573, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=203, Percent_Identity=31.5270935960591, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=31.0861423220974, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=27.4193548387097, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=31.6793893129771, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=210, Percent_Identity=34.2857142857143, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=28.8973384030418, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.5343511450382, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=239, Percent_Identity=30.9623430962343, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=208, Percent_Identity=28.3653846153846, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=27.0161290322581, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=27.6515151515151, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=216, Percent_Identity=33.7962962962963, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=29.3193717277487, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=198, Percent_Identity=30.8080808080808, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=29.6875, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=26.4822134387352, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=204, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=28.0632411067194, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=25.1012145748988, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=208, Percent_Identity=28.3653846153846, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=207, Percent_Identity=30.9178743961353, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=27.4590163934426, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=27.4131274131274, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=27.4131274131274, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=234, Percent_Identity=29.9145299145299, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=237, Percent_Identity=30.379746835443, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=197, Percent_Identity=28.4263959390863, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=27.9187817258883, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.8774703557312, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=196, Percent_Identity=29.0816326530612, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=26.0416666666667, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=25.78125, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=27.2251308900524, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=30.0395256916996, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=26.8482490272374, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=30.241935483871, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=28.8, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=32.4110671936759, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=28.7449392712551, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.9352226720648, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=27.1317829457364, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24580925, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644337, Length=201, Percent_Identity=25.8706467661692, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=27.7486910994764, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357673, Length=196, Percent_Identity=25.5102040816327, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 26460; Mature: 26329

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQANLAGQVALIIGASRNMGRAFAAALAADGAAVAIHYHSAGSRAGAEEAAAAILAAGG
CCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCC
QAFAVQADVTKVAEVRRLFDAVEERFGHLDILINTAGMMVKKAITEVSEEEFDAIFALNT
CEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCEEEEECC
KAAFFALQEAGRRIRDNGRIVSVGTSLLAATTGHYGAYAGSKAPLEDFTRALAKEIGHRG
HHHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
VTVNVVAPGPMDTEFFYAAETPEAVAYLKRASINGELGQVADLVPLVKHLVSPENRWTTA
EEEEEEECCCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
QTLFINGGFVSR
EEEEEECCCCCC
>Mature Secondary Structure 
SQANLAGQVALIIGASRNMGRAFAAALAADGAAVAIHYHSAGSRAGAEEAAAAILAAGG
CCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCC
QAFAVQADVTKVAEVRRLFDAVEERFGHLDILINTAGMMVKKAITEVSEEEFDAIFALNT
CEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCEEEEECC
KAAFFALQEAGRRIRDNGRIVSVGTSLLAATTGHYGAYAGSKAPLEDFTRALAKEIGHRG
HHHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
VTVNVVAPGPMDTEFFYAAETPEAVAYLKRASINGELGQVADLVPLVKHLVSPENRWTTA
EEEEEEECCCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
QTLFINGGFVSR
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8868443 [H]