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The map label for this gene is dsbG [H]

Identifier: 34498092

GI number: 34498092

Start: 2845721

End: 2846464

Strand: Direct

Name: dsbG [H]

Synonym: CV_2637

Alternate gene names: 34498092

Gene position: 2845721-2846464 (Clockwise)

Preceding gene: 34498091

Following gene: 34498095

Centisome position: 59.9

GC content: 71.77

Gene sequence:

>744_bases
ATGAAACCCGCTTGCGCCGTGGCTATCGCCGTGGGCCACGCCTCATTGTCCGCCGCAGCCGCAGCAGCAGCGGCCTGGCC
CGCCCCCATCCAGGCATTGGAACAGCAAGGCTACGAAATCCTGGGCCGGTTCGACGGCCCGTCCGGCATGGCCGGCTACG
CCGCGCTGCGCCTGGGCCGCCCGCAAACGCTGTACCTGACGCCGGACGGCAAGTATGCGATCGCGGGGACGATGACGGAT
GGCGGCGGCGAGAATTGGAACCAAGCCGGCGTCGACCAGCGCTTCAGCGACGCGATGTGGGAACAATTGCAAGGCAGCGC
CTGGATCGCGGACGGCTCCCGGACGGCGGAGCGCGTGGTTTACCTGTTCACCGACCCCAACTGCCCGTACTGCAGGCAGT
TCTGGCGCGACGCCCGCCCCTGGGTGCGCTCCGGCAAGGTGCAGCTGCGCCATATCCTGATCGGCATTCTCCAGGCCGAC
AGCCGCGGCAAGGCGGCCGCCATCCTGGCCGACGCCGATCCCGCCCGCGCGCTGGCGCGGCACGAGGGCGGCGCCGACAC
CCGTCCGCTGGGCCAGCCGCCGGCAGCCGTCGAGGCCAGGCTCGACGCCAACCACAGGCTGATGGAGAGGCTGGGCGCGT
TCGCCACCCCGGCGATTTACTACCGCGCCGCGGACGGCTCGCTGCAGAAGGCCCAGGGCGCCCCGGGCGCGGCGGCGCTG
CCGAAAATCCTGGGGCCGCGCTGA

Upstream 100 bases:

>100_bases
GAGAATCCCCTCCCGTCCGGACGACACCCCGCCTAACCCGGACAATTGAACTCAAAGCGTCTCGTTTCCTCCAAGCGACT
GCCAACAAGGAGAAAACAGC

Downstream 100 bases:

>100_bases
GCGGCGGAAGCAAAAACAGGCATGGCCGCGCCATGCCTGTCCGCCGCGCCTTTTCGGCTCATGCCGCCAGCGGCTGCTCG
ACCAGTCCGGGGAAGGCCAG

Product: disulfide isomerase/thiol-disulfide oxidase

Products: protein with oxidized disulfide bonds [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKPACAVAIAVGHASLSAAAAAAAAWPAPIQALEQQGYEILGRFDGPSGMAGYAALRLGRPQTLYLTPDGKYAIAGTMTD
GGGENWNQAGVDQRFSDAMWEQLQGSAWIADGSRTAERVVYLFTDPNCPYCRQFWRDARPWVRSGKVQLRHILIGILQAD
SRGKAAAILADADPARALARHEGGADTRPLGQPPAAVEARLDANHRLMERLGAFATPAIYYRAADGSLQKAQGAPGAAAL
PKILGPR

Sequences:

>Translated_247_residues
MKPACAVAIAVGHASLSAAAAAAAAWPAPIQALEQQGYEILGRFDGPSGMAGYAALRLGRPQTLYLTPDGKYAIAGTMTD
GGGENWNQAGVDQRFSDAMWEQLQGSAWIADGSRTAERVVYLFTDPNCPYCRQFWRDARPWVRSGKVQLRHILIGILQAD
SRGKAAAILADADPARALARHEGGADTRPLGQPPAAVEARLDANHRLMERLGAFATPAIYYRAADGSLQKAQGAPGAAAL
PKILGPR
>Mature_247_residues
MKPACAVAIAVGHASLSAAAAAAAAWPAPIQALEQQGYEILGRFDGPSGMAGYAALRLGRPQTLYLTPDGKYAIAGTMTD
GGGENWNQAGVDQRFSDAMWEQLQGSAWIADGSRTAERVVYLFTDPNCPYCRQFWRDARPWVRSGKVQLRHILIGILQAD
SRGKAAAILADADPARALARHEGGADTRPLGQPPAAVEARLDANHRLMERLGAFATPAIYYRAADGSLQKAQGAPGAAAL
PKILGPR

Specific function: Involved in disulfide bond formation. Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC. DsbG is maintained in a reduced state by DsbD [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081762, Length=232, Percent_Identity=42.2413793103448, Blast_Score=199, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26173; Mature: 26173

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPACAVAIAVGHASLSAAAAAAAAWPAPIQALEQQGYEILGRFDGPSGMAGYAALRLGR
CCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHEECCC
PQTLYLTPDGKYAIAGTMTDGGGENWNQAGVDQRFSDAMWEQLQGSAWIADGSRTAERVV
CCEEEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEE
YLFTDPNCPYCRQFWRDARPWVRSGKVQLRHILIGILQADSRGKAAAILADADPARALAR
EEEECCCCHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
HEGGADTRPLGQPPAAVEARLDANHRLMERLGAFATPAIYYRAADGSLQKAQGAPGAAAL
CCCCCCCCCCCCCCHHHEECCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHCCCCCHHHH
PKILGPR
HHHCCCC
>Mature Secondary Structure
MKPACAVAIAVGHASLSAAAAAAAAWPAPIQALEQQGYEILGRFDGPSGMAGYAALRLGR
CCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHEECCC
PQTLYLTPDGKYAIAGTMTDGGGENWNQAGVDQRFSDAMWEQLQGSAWIADGSRTAERVV
CCEEEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEE
YLFTDPNCPYCRQFWRDARPWVRSGKVQLRHILIGILQADSRGKAAAILADADPARALAR
EEEECCCCHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
HEGGADTRPLGQPPAAVEARLDANHRLMERLGAFATPAIYYRAADGSLQKAQGAPGAAAL
CCCCCCCCCCCCCCHHHEECCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHCCCCCHHHH
PKILGPR
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein with reduced SH groups [C]

Specific reaction: protein with reduced SH groups = protein with oxidized disulfide bonds [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]