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The map label for this gene is escU [H]

Identifier: 34498065

GI number: 34498065

Start: 2818175

End: 2819230

Strand: Direct

Name: escU [H]

Synonym: CV_2610

Alternate gene names: 34498065

Gene position: 2818175-2819230 (Clockwise)

Preceding gene: 34498064

Following gene: 34498066

Centisome position: 59.32

GC content: 55.87

Gene sequence:

>1056_bases
ATGAGCGAGAAAACCGAAAAACCCACCCCCAAGAAAATTCGGGACGCCCGCAACAAGGGACAGGTGGCCAAGAGCACCGA
GATCACCAGCGGCGTGCAATTAGCCGTATTGCTCGCGTATTTCTGCTTCGAAGGTCCCCATCTGCTGCAAGCGCTGCAGG
GGATGCTCAATGTCGCGATCAGCGTCGTCAACCAGGATCTCGTCTTCGGCATCAATCAATTAACCGGCGCCTTCCTCGAG
CTCGCCATGCGCTTTCTCGGCGGCATCGCCGCGCTGGTCATTATCATGACCATCGCAGCGGTCATCGCGCAGATCGGCCC
CTTGCTGGCGACGGAAGCGCTGAAGCCGTCGTTGGAGAAGTTGAATCCGGTCTCCAACCTCAAGCAGATGTTCTCGATGC
GCAGCCTGTTCGAGTTCATGAAGTCCATCTTCAAAGTGACGATATTGTCGCTGATTTTCTTCTACCTGCTGCGACAGTAC
AGCCCATCCATCCAATTTCTGCCCTTGAGCGATGTCGCGACCGGCATGCGCGTCAGCACCCAGCTGCTGTTCTGGATGTG
GGCTTCGTTGATTGGCTTTTACATCATTTTCGGCATCGCCGATTTCGCCTTCCAGCGTTACAACACGACCAAACAACTGA
TGATGTCTCTTGAAGACATCAAGCAGGAATTCAAAAACTCGGAAGGCAATCCCGAGATCAAGCAAAAGCGCAAGGAAGCG
CATCGCGAGATTCAAAGCGGCAGCCTGGCCGACAATGTTTCCAAATCCACCGCGGTGGTCCGCAACCCCACCCACATCGC
GGTTTGCCTGCGCTACCAGCCCGGCGAAACTCCTCTCCCTCAGGTGACCGCAGTCGGCCGCGATGCGATGGCCTTGCATA
TCGTGAAGCTGGCCGAAAAAGCCGGCATCCCGGTGGTGGAAAACATTGAAGTCGCGCGCGCGCTGGCCGCGAAAACCAAG
ATCGGCGGGTACATATCCGCCGAGCTATTCGAACCGGTTGCGCAGATCCTGCGCTTGGCCATGAATATTAACTATGACGA
TGAAGACGATGATTGA

Upstream 100 bases:

>100_bases
TGCTGATGCTGATCGTCAGCCTGAGCTTCGCCTTCAACGGCTTGCTGGATTACAGCGCGCATTTCACCAAGCTGACCGAC
GCCTTGCTGGAGCAGTTGAG

Downstream 100 bases:

>100_bases
CATCAAGCCCATTATCAGGTTTCTGCTATGTAGTGTCAGCTTGGTTTCGCATGCGTGGGCAGCCCCGCTTGCCGAGTCCT
CTCCATCCCAATCCGCGCCC

Product: secretion system apparatus protein SsaU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSEKTEKPTPKKIRDARNKGQVAKSTEITSGVQLAVLLAYFCFEGPHLLQALQGMLNVAISVVNQDLVFGINQLTGAFLE
LAMRFLGGIAALVIIMTIAAVIAQIGPLLATEALKPSLEKLNPVSNLKQMFSMRSLFEFMKSIFKVTILSLIFFYLLRQY
SPSIQFLPLSDVATGMRVSTQLLFWMWASLIGFYIIFGIADFAFQRYNTTKQLMMSLEDIKQEFKNSEGNPEIKQKRKEA
HREIQSGSLADNVSKSTAVVRNPTHIAVCLRYQPGETPLPQVTAVGRDAMALHIVKLAEKAGIPVVENIEVARALAAKTK
IGGYISAELFEPVAQILRLAMNINYDDEDDD

Sequences:

>Translated_351_residues
MSEKTEKPTPKKIRDARNKGQVAKSTEITSGVQLAVLLAYFCFEGPHLLQALQGMLNVAISVVNQDLVFGINQLTGAFLE
LAMRFLGGIAALVIIMTIAAVIAQIGPLLATEALKPSLEKLNPVSNLKQMFSMRSLFEFMKSIFKVTILSLIFFYLLRQY
SPSIQFLPLSDVATGMRVSTQLLFWMWASLIGFYIIFGIADFAFQRYNTTKQLMMSLEDIKQEFKNSEGNPEIKQKRKEA
HREIQSGSLADNVSKSTAVVRNPTHIAVCLRYQPGETPLPQVTAVGRDAMALHIVKLAEKAGIPVVENIEVARALAAKTK
IGGYISAELFEPVAQILRLAMNINYDDEDDD
>Mature_350_residues
SEKTEKPTPKKIRDARNKGQVAKSTEITSGVQLAVLLAYFCFEGPHLLQALQGMLNVAISVVNQDLVFGINQLTGAFLEL
AMRFLGGIAALVIIMTIAAVIAQIGPLLATEALKPSLEKLNPVSNLKQMFSMRSLFEFMKSIFKVTILSLIFFYLLRQYS
PSIQFLPLSDVATGMRVSTQLLFWMWASLIGFYIIFGIADFAFQRYNTTKQLMMSLEDIKQEFKNSEGNPEIKQKRKEAH
REIQSGSLADNVSKSTAVVRNPTHIAVCLRYQPGETPLPQVTAVGRDAMALHIVKLAEKAGIPVVENIEVARALAAKTKI
GGYISAELFEPVAQILRLAMNINYDDEDDD

Specific function: Part of a type III secretion system [H]

COG id: COG4792

COG function: function code U; Type III secretory pathway, component EscU

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family [H]

Homologues:

Organism=Escherichia coli, GI1788188, Length=345, Percent_Identity=30.1449275362319, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006135
- InterPro:   IPR006307 [H]

Pfam domain/function: PF01312 Bac_export_2 [H]

EC number: NA

Molecular weight: Translated: 38934; Mature: 38803

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SEKTEKPTPKKIRDARNKGQVAKSTEITSGVQLAVLLAYFCFEGPHLLQALQGMLNVAI
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SVVNQDLVFGINQLTGAFLELAMRFLGGIAALVIIMTIAAVIAQIGPLLATEALKPSLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LNPVSNLKQMFSMRSLFEFMKSIFKVTILSLIFFYLLRQYSPSIQFLPLSDVATGMRVST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
QLLFWMWASLIGFYIIFGIADFAFQRYNTTKQLMMSLEDIKQEFKNSEGNPEIKQKRKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HREIQSGSLADNVSKSTAVVRNPTHIAVCLRYQPGETPLPQVTAVGRDAMALHIVKLAEK
HHHHHCCCHHHHHHHHHHHEECCCEEEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHH
AGIPVVENIEVARALAAKTKIGGYISAELFEPVAQILRLAMNINYDDEDDD
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9140973; 11677609 [H]