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The map label for this gene is luxQ [H]

Identifier: 34497853

GI number: 34497853

Start: 2581094

End: 2581858

Strand: Reverse

Name: luxQ [H]

Synonym: CV_2398

Alternate gene names: 34497853

Gene position: 2581858-2581094 (Counterclockwise)

Preceding gene: 34497855

Following gene: 34497852

Centisome position: 54.34

GC content: 63.27

Gene sequence:

>765_bases
ATGAAGCAAGGGGATTGCGCTGGCGCGAAACCGTCCAGGCTGAGCGTCCTGCTGGTGGATGACAGCGAGATCAATCGCTT
GTTCGTATCCAGCCTGGCTGAAGATTTGGGGATTGCCCTGGATTGCGCAAACGATGGCGCCGAAGCCGTGAGGCTGCTTA
GAGATCACGGCGGGCGCTATCAGCTGGTTCTGATGGACCTGCAAATGCCCGTGCTGGACGGATTGGGCGCGACCCGGACC
ATCCGGGAGGAATTGCAGCTTGGGCTGCCCATCATCGCGCTGACCGCCAGCGCCGATCCGGAGCAGAGGGAAAATTGTCG
CCGGGCGGGCATGAACGGTTTCCTGCTCAAACCGGTGGAGGGCGAAAGACTGTCGCAACTGATCGACCACTATCGCGCCT
GCAACGATGCCAGCGGGGAATACGGCAAACTGAAGCTTGGCACGCTGGACTTGTTGCACCGCGCCTCCGCGGCGCGCCTG
TCCAGCACTCTTCGTGAGGCCGTCGCCACCTGTCGGGAAGAATTCGATCAGGCTTGCCAGCAGTGGCGGGAAGGCGACGC
GGAGGCTGCCGCGCGGCTGATTCACCGCTACCGCGGCTCGCTGGGCACCTTCGCCCACGACGGCTTCGTGCGGCAGACGC
TGGATCTTGAGCATGCGGTGCGGCAGGGAGAAAAAGACCTGGAATCCCGTTTCGACGCTTTTCGCGCGGAACTGGACGAG
CTGCGGCGCCAGCTTCAGCTGTGGATGGAGAGCCGGGCCGACTGA

Upstream 100 bases:

>100_bases
TACAGCTATAGCTCTTCCATCGGCGCGCGGCACCCGAGCCTGCATGATGCGTGCGGCATTTTCATACCCGAAACGAAACG
CGCGTGCCGCTGGAGGATCT

Downstream 100 bases:

>100_bases
AATTCGCCGCCGCGTGCCCCGGGAGCCGCATTTTGATAGAATTACGTCTCATTAGCCGCCAATCATCGCAAACCCACTCA
TGAGCATACAAATCAAAGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKQGDCAGAKPSRLSVLLVDDSEINRLFVSSLAEDLGIALDCANDGAEAVRLLRDHGGRYQLVLMDLQMPVLDGLGATRT
IREELQLGLPIIALTASADPEQRENCRRAGMNGFLLKPVEGERLSQLIDHYRACNDASGEYGKLKLGTLDLLHRASAARL
SSTLREAVATCREEFDQACQQWREGDAEAAARLIHRYRGSLGTFAHDGFVRQTLDLEHAVRQGEKDLESRFDAFRAELDE
LRRQLQLWMESRAD

Sequences:

>Translated_254_residues
MKQGDCAGAKPSRLSVLLVDDSEINRLFVSSLAEDLGIALDCANDGAEAVRLLRDHGGRYQLVLMDLQMPVLDGLGATRT
IREELQLGLPIIALTASADPEQRENCRRAGMNGFLLKPVEGERLSQLIDHYRACNDASGEYGKLKLGTLDLLHRASAARL
SSTLREAVATCREEFDQACQQWREGDAEAAARLIHRYRGSLGTFAHDGFVRQTLDLEHAVRQGEKDLESRFDAFRAELDE
LRRQLQLWMESRAD
>Mature_254_residues
MKQGDCAGAKPSRLSVLLVDDSEINRLFVSSLAEDLGIALDCANDGAEAVRLLRDHGGRYQLVLMDLQMPVLDGLGATRT
IREELQLGLPIIALTASADPEQRENCRRAGMNGFLLKPVEGERLSQLIDHYRACNDASGEYGKLKLGTLDLLHRASAARL
SSTLREAVATCREEFDQACQQWREGDAEAAARLIHRYRGSLGTFAHDGFVRQTLDLEHAVRQGEKDLESRFDAFRAELDE
LRRQLQLWMESRAD

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=194, Percent_Identity=29.8969072164948, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=141, Percent_Identity=35.4609929078014, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=203, Percent_Identity=30.0492610837438, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI48994928, Length=128, Percent_Identity=35.15625, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322044, Length=126, Percent_Identity=36.5079365079365, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 28321; Mature: 28321

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQGDCAGAKPSRLSVLLVDDSEINRLFVSSLAEDLGIALDCANDGAEAVRLLRDHGGRY
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHCCCCE
QLVLMDLQMPVLDGLGATRTIREELQLGLPIIALTASADPEQRENCRRAGMNGFLLKPVE
EEEEEECCHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCEEECCCC
GERLSQLIDHYRACNDASGEYGKLKLGTLDLLHRASAARLSSTLREAVATCREEFDQACQ
CHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWREGDAEAAARLIHRYRGSLGTFAHDGFVRQTLDLEHAVRQGEKDLESRFDAFRAELDE
HHHCCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LRRQLQLWMESRAD
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKQGDCAGAKPSRLSVLLVDDSEINRLFVSSLAEDLGIALDCANDGAEAVRLLRDHGGRY
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHCCCCE
QLVLMDLQMPVLDGLGATRTIREELQLGLPIIALTASADPEQRENCRRAGMNGFLLKPVE
EEEEEECCHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCEEECCCC
GERLSQLIDHYRACNDASGEYGKLKLGTLDLLHRASAARLSSTLREAVATCREEFDQACQ
CHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWREGDAEAAARLIHRYRGSLGTFAHDGFVRQTLDLEHAVRQGEKDLESRFDAFRAELDE
HHHCCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LRRQLQLWMESRAD
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA