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The map label for this gene is map1 [H]

Identifier: 34497852

GI number: 34497852

Start: 2580217

End: 2581014

Strand: Reverse

Name: map1 [H]

Synonym: CV_2397

Alternate gene names: 34497852

Gene position: 2581014-2580217 (Counterclockwise)

Preceding gene: 34497853

Following gene: 34497851

Centisome position: 54.32

GC content: 61.15

Gene sequence:

>798_bases
ATGAGCATACAAATCAAAGACGCGCAGGATATCGAGAAGATGCGCATCGCCGGCCGCCTGGCGTCCGAAGTTTTGGATTT
CATCACCCCGCACATCAAGCCCGGCATCACCACCGAGGCCATCGACAAGCTGTGCCACGACTACATGGTCAACGTGCAGG
GCACCATTCCCGCCCCGCTGAACTACGCGCCGGACGGCCACAATCCTTATCCCAAGTCGGTATGCACCTCGGTCAACCAC
GTGATCTGCCACGGCATCCCCAATGACAAGCCGCTGAAAAACGGCGACATCATGAATCTGGACATCACCGTGATCAAGGA
TGGCTACCACGGCGATACCAGCCGCATGTTCTTCGTCGGCGACGTCAGCCCGCATGCCAAGCGCCTGAGCAAGATCACCT
ACGAAGCCATGTGGAAAGGCATCGAGAAGGTGAAGCCGGGCGCCACGCTCGGCGACATCGGCTACGCGGTGCAAAGCTAC
GCCGAAAGCGCCGGCTACAGCGTGGTGCAGGAATTCTGCGGCCACGGCATCGGCAAGAAATTCCACGAGGAGCCGCAGAT
CCTGCACTACGGCCGTCCGGGCACCGGGCTGGAGATCCAGGCCGGCATGATCTTCACCATCGAGCCGATGATCAACCAGG
GCAAGCGCCATCTGCGCATGCTGGCCGACGGCTGGACCGTGGTCACCAAGGACCGCAGCCTGTCCGCCCAGTGGGAGCAC
ACCGTGCTGGTCACCGAAACCGGCTACGAAATCCTCACCCAGTCCGCGGGCACGCCGGACAAGCCGAGCTTCAAATAA

Upstream 100 bases:

>100_bases
ATGGAGAGCCGGGCCGACTGAAATTCGCCGCCGCGTGCCCCGGGAGCCGCATTTTGATAGAATTACGTCTCATTAGCCGC
CAATCATCGCAAACCCACTC

Downstream 100 bases:

>100_bases
TCTTCCAGGCCGTCCGCATCCGCGGCGGCCTTCTTCCGCTCAGCCATGCTGCCAGATGTTTTCCGCGCCGATACAGGCTC
CCGTTCGCTGATACAAGCCC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSIQIKDAQDIEKMRIAGRLASEVLDFITPHIKPGITTEAIDKLCHDYMVNVQGTIPAPLNYAPDGHNPYPKSVCTSVNH
VICHGIPNDKPLKNGDIMNLDITVIKDGYHGDTSRMFFVGDVSPHAKRLSKITYEAMWKGIEKVKPGATLGDIGYAVQSY
AESAGYSVVQEFCGHGIGKKFHEEPQILHYGRPGTGLEIQAGMIFTIEPMINQGKRHLRMLADGWTVVTKDRSLSAQWEH
TVLVTETGYEILTQSAGTPDKPSFK

Sequences:

>Translated_265_residues
MSIQIKDAQDIEKMRIAGRLASEVLDFITPHIKPGITTEAIDKLCHDYMVNVQGTIPAPLNYAPDGHNPYPKSVCTSVNH
VICHGIPNDKPLKNGDIMNLDITVIKDGYHGDTSRMFFVGDVSPHAKRLSKITYEAMWKGIEKVKPGATLGDIGYAVQSY
AESAGYSVVQEFCGHGIGKKFHEEPQILHYGRPGTGLEIQAGMIFTIEPMINQGKRHLRMLADGWTVVTKDRSLSAQWEH
TVLVTETGYEILTQSAGTPDKPSFK
>Mature_264_residues
SIQIKDAQDIEKMRIAGRLASEVLDFITPHIKPGITTEAIDKLCHDYMVNVQGTIPAPLNYAPDGHNPYPKSVCTSVNHV
ICHGIPNDKPLKNGDIMNLDITVIKDGYHGDTSRMFFVGDVSPHAKRLSKITYEAMWKGIEKVKPGATLGDIGYAVQSYA
ESAGYSVVQEFCGHGIGKKFHEEPQILHYGRPGTGLEIQAGMIFTIEPMINQGKRHLRMLADGWTVVTKDRSLSAQWEHT
VLVTETGYEILTQSAGTPDKPSFK

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=262, Percent_Identity=47.3282442748092, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI40385867, Length=253, Percent_Identity=41.897233201581, Blast_Score=205, Evalue=3e-53,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=56.6929133858268, Blast_Score=313, Evalue=7e-87,
Organism=Escherichia coli, GI1788728, Length=214, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71996291, Length=263, Percent_Identity=42.5855513307985, Blast_Score=219, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6323273, Length=253, Percent_Identity=43.8735177865613, Blast_Score=215, Evalue=7e-57,
Organism=Drosophila melanogaster, GI21355531, Length=262, Percent_Identity=45.8015267175573, Blast_Score=235, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24583427, Length=253, Percent_Identity=41.501976284585, Blast_Score=204, Evalue=4e-53,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29261; Mature: 29130

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQIKDAQDIEKMRIAGRLASEVLDFITPHIKPGITTEAIDKLCHDYMVNVQGTIPAPL
CEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCC
NYAPDGHNPYPKSVCTSVNHVICHGIPNDKPLKNGDIMNLDITVIKDGYHGDTSRMFFVG
CCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEE
DVSPHAKRLSKITYEAMWKGIEKVKPGATLGDIGYAVQSYAESAGYSVVQEFCGHGIGKK
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
FHEEPQILHYGRPGTGLEIQAGMIFTIEPMINQGKRHLRMLADGWTVVTKDRSLSAQWEH
HCCCCCEEEECCCCCCCEEECCEEEEECHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCE
TVLVTETGYEILTQSAGTPDKPSFK
EEEEEECCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIQIKDAQDIEKMRIAGRLASEVLDFITPHIKPGITTEAIDKLCHDYMVNVQGTIPAPL
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCC
NYAPDGHNPYPKSVCTSVNHVICHGIPNDKPLKNGDIMNLDITVIKDGYHGDTSRMFFVG
CCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEE
DVSPHAKRLSKITYEAMWKGIEKVKPGATLGDIGYAVQSYAESAGYSVVQEFCGHGIGKK
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHH
FHEEPQILHYGRPGTGLEIQAGMIFTIEPMINQGKRHLRMLADGWTVVTKDRSLSAQWEH
HCCCCCEEEECCCCCCCEEECCEEEEECHHHHCCHHHHHHHHCCCEEEEECCCCCCCCCE
TVLVTETGYEILTQSAGTPDKPSFK
EEEEEECCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]