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The map label for this gene is ribAB [H]

Identifier: 34497844

GI number: 34497844

Start: 2570968

End: 2572092

Strand: Direct

Name: ribAB [H]

Synonym: CV_2389

Alternate gene names: 34497844

Gene position: 2570968-2572092 (Clockwise)

Preceding gene: 34497843

Following gene: 34497845

Centisome position: 54.11

GC content: 65.78

Gene sequence:

>1125_bases
ATGACCATATCTCCGATCCAAGACATCATCGCCGACATCCAGGCCGGCAAGATGGTGGTGCTGATGGACGCCGAAGACCG
CGAGAACGAAGGCGACCTGGTGATGGCGGCCGAGTTCGTCACGCCGGAAGCGATCAACTTCATGGCCAAATACGGCCGCG
GCCTGATCTGCCTGACACTGACCGAAGAGCGCTGCAAGCTGTTGAACCTCCCTATGATGGCGACCAACAACGGCACCAGT
TTCGGCACCAATTTCACCGTGTCGGTGGAAGCGGCCGAGGGCGTCACCACCGGCATTTCCGCCGCCGACCGCGCCCACAC
CATCAAGACCGCCGTCGCGCGGCTGGCCAAGGCCAGCGACCTGGTCCAGCCCGGCCACGTGTTCCCGCTGAAGGCGCAGA
ACGGTGGCGTGTTGATCCGCGCCGGCCATACCGAGGCCGGCTGCGACCTGGCGATGCTGGCGGGCGTGGAGCCGGCCGGC
GTGATCTGCGAGATCATGAACGACGACGGCACCATGGCGCGCTTGCCGGAGCTGCTGGAGTTCGCCAAGCAGCACGGACT
GAAGATAGGCACCATCTCCGATCTGATCCAGCACCGCAGCCGCACCGAATCCCTGGTGGAGAAAGTGGGCGAGCGTCCGG
TGGAGACCCCGTTCGGCAGCTTCGACCTGCACGTGTTCCGCGACATCACCACCTCCGCGACCCATCTGGCGCTGAGCAAG
GGCAAGATACGCCCCGACAAGGAAATCCTGGTGCGGGTGCATGAGCCGCTGTCGGTGATAGACGTGCTGGCGCCGCTGTG
CAGCCACCACTCCTGGACGCTGCCCAACGCGCTGGAAACCATGGAGGAAGAGGGCTGCGGCGTGATGGTGCTGCTGTACC
GCGACGAGACCGGCGCCGATCTGGCGCAGCGCGCGCTGGACCAGGAGCCGCCGCGGCAGAAATGGGACAGCAAGACCTTC
GGCATCGGCGCCCAGATGCTGAAGGCGCTGGGCGTGGGCAAGATGAAGCTGATGTCCAGCCCGGTGAGCCTGCCGTCGAT
GGCCGGCTTCGAGCTCGAAGTGACCGGATTCTGCCAGCCCGGGCACTTCCACGTGGACCGGGACGGCGGTCCGGGCGTGG
CCTAA

Upstream 100 bases:

>100_bases
CGCTGGCGCTGCGAGACGGCGAGGCGGCCAAGCTCGGCGAATACCGGGCGCTGGATTTGCTGCCCGCGTAGAACGGGCGA
ACCGACAAAGGAATAGAGCA

Downstream 100 bases:

>100_bases
TCGCGGCGATTGCGTTACAATTGCCGGCTTTCCTTAGTGTTTTCGCCGCGAGGACCCAACATGCTTGACGCCATCCAGTG
TATTGAACCCAATTTTTCCG

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTISPIQDIIADIQAGKMVVLMDAEDRENEGDLVMAAEFVTPEAINFMAKYGRGLICLTLTEERCKLLNLPMMATNNGTS
FGTNFTVSVEAAEGVTTGISAADRAHTIKTAVARLAKASDLVQPGHVFPLKAQNGGVLIRAGHTEAGCDLAMLAGVEPAG
VICEIMNDDGTMARLPELLEFAKQHGLKIGTISDLIQHRSRTESLVEKVGERPVETPFGSFDLHVFRDITTSATHLALSK
GKIRPDKEILVRVHEPLSVIDVLAPLCSHHSWTLPNALETMEEEGCGVMVLLYRDETGADLAQRALDQEPPRQKWDSKTF
GIGAQMLKALGVGKMKLMSSPVSLPSMAGFELEVTGFCQPGHFHVDRDGGPGVA

Sequences:

>Translated_374_residues
MTISPIQDIIADIQAGKMVVLMDAEDRENEGDLVMAAEFVTPEAINFMAKYGRGLICLTLTEERCKLLNLPMMATNNGTS
FGTNFTVSVEAAEGVTTGISAADRAHTIKTAVARLAKASDLVQPGHVFPLKAQNGGVLIRAGHTEAGCDLAMLAGVEPAG
VICEIMNDDGTMARLPELLEFAKQHGLKIGTISDLIQHRSRTESLVEKVGERPVETPFGSFDLHVFRDITTSATHLALSK
GKIRPDKEILVRVHEPLSVIDVLAPLCSHHSWTLPNALETMEEEGCGVMVLLYRDETGADLAQRALDQEPPRQKWDSKTF
GIGAQMLKALGVGKMKLMSSPVSLPSMAGFELEVTGFCQPGHFHVDRDGGPGVA
>Mature_373_residues
TISPIQDIIADIQAGKMVVLMDAEDRENEGDLVMAAEFVTPEAINFMAKYGRGLICLTLTEERCKLLNLPMMATNNGTSF
GTNFTVSVEAAEGVTTGISAADRAHTIKTAVARLAKASDLVQPGHVFPLKAQNGGVLIRAGHTEAGCDLAMLAGVEPAGV
ICEIMNDDGTMARLPELLEFAKQHGLKIGTISDLIQHRSRTESLVEKVGERPVETPFGSFDLHVFRDITTSATHLALSKG
KIRPDKEILVRVHEPLSVIDVLAPLCSHHSWTLPNALETMEEEGCGVMVLLYRDETGADLAQRALDQEPPRQKWDSKTFG
IGAQMLKALGVGKMKLMSSPVSLPSMAGFELEVTGFCQPGHFHVDRDGGPGVA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=198, Percent_Identity=54.5454545454545, Blast_Score=230, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=40.6862745098039, Blast_Score=161, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40265; Mature: 40134

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPIQDIIADIQAGKMVVLMDAEDRENEGDLVMAAEFVTPEAINFMAKYGRGLICLTL
CCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TEERCKLLNLPMMATNNGTSFGTNFTVSVEAAEGVTTGISAADRAHTIKTAVARLAKASD
CHHHHHHHCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVQPGHVFPLKAQNGGVLIRAGHTEAGCDLAMLAGVEPAGVICEIMNDDGTMARLPELLE
CCCCCCEEEEEECCCCEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHH
FAKQHGLKIGTISDLIQHRSRTESLVEKVGERPVETPFGSFDLHVFRDITTSATHLALSK
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHCCHHHEEEEC
GKIRPDKEILVRVHEPLSVIDVLAPLCSHHSWTLPNALETMEEEGCGVMVLLYRDETGAD
CCCCCCHHHEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCHH
LAQRALDQEPPRQKWDSKTFGIGAQMLKALGVGKMKLMSSPVSLPSMAGFELEVTGFCQP
HHHHHHCCCCCHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEEECC
GHFHVDRDGGPGVA
CCEEEECCCCCCCC
>Mature Secondary Structure 
TISPIQDIIADIQAGKMVVLMDAEDRENEGDLVMAAEFVTPEAINFMAKYGRGLICLTL
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TEERCKLLNLPMMATNNGTSFGTNFTVSVEAAEGVTTGISAADRAHTIKTAVARLAKASD
CHHHHHHHCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVQPGHVFPLKAQNGGVLIRAGHTEAGCDLAMLAGVEPAGVICEIMNDDGTMARLPELLE
CCCCCCEEEEEECCCCEEEEECCCCCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHH
FAKQHGLKIGTISDLIQHRSRTESLVEKVGERPVETPFGSFDLHVFRDITTSATHLALSK
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHCCHHHEEEEC
GKIRPDKEILVRVHEPLSVIDVLAPLCSHHSWTLPNALETMEEEGCGVMVLLYRDETGAD
CCCCCCHHHEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCHH
LAQRALDQEPPRQKWDSKTFGIGAQMLKALGVGKMKLMSSPVSLPSMAGFELEVTGFCQP
HHHHHHCCCCCHHHCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEEECC
GHFHVDRDGGPGVA
CCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]