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The map label for this gene is orn

Identifier: 34497823

GI number: 34497823

Start: 2553280

End: 2553825

Strand: Direct

Name: orn

Synonym: CV_2368

Alternate gene names: 34497823

Gene position: 2553280-2553825 (Clockwise)

Preceding gene: 34497817

Following gene: 34497824

Centisome position: 53.74

GC content: 59.34

Gene sequence:

>546_bases
ATGGCACAAGATACCAATAACCTCATCTGGCTCGACATGGAGATGACGGGCCTGAACCCGGATCAGGACCGCATCATCGA
GGTGGCGATGATCGTCACCGACAGCAATCTGAACGTCCTGGCGGAGTCGCCGGTGCTGGTGATTCACCAGCCGGACGCCA
TTCTGGACGGCATGGACGACTGGAACAAGAACACCCACGGCAAGAGCGGGCTGATCGAAAAGGTGAAGAATTCCACGGTC
AGCGAAGCCGAGGCGGAGCAACTGCTGCTGGAGTTCATGATGCAGCACGTGCCGGAGCGCGCGACGCCGATGTGCGGCAA
CACCATCCATCAGGACCGCCGCTTCATGGCGCGCTGGATGCCGAAGCTGGAAGCCTATTTCCATTACCGCAACCTGGACG
TGTCCACGTTGAAGGAGTTGTGCAAGCGCTGGCGTCCCGAAATCGCCAAGGGCGTGGTCAAGCGCGGCAAGCATGAGGCG
CTGGCGGACATCCTGGAGTCGATAGAGGAAATGCGCTACTACCGCGAGCACTTCCTCAAGGTATAA

Upstream 100 bases:

>100_bases
GGCGAACAGTAGGGAGAAAGCCTCGGTCATGGGTGTCCTGGAGTTTGCCGACGACGCGGCAATGAAGGAAAATGGCAGGG
TTTTCTAAAGATTGACTAGT

Downstream 100 bases:

>100_bases
GCTACGCCGTGTCGAGCCGGCTCGAGCGGGCCGGCTTTTTCACATTCACCTTGTATTCCATTGGCAGAAAACATGGCCGC
ACAACGCCACATCGACATCA

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAQDTNNLIWLDMEMTGLNPDQDRIIEVAMIVTDSNLNVLAESPVLVIHQPDAILDGMDDWNKNTHGKSGLIEKVKNSTV
SEAEAEQLLLEFMMQHVPERATPMCGNTIHQDRRFMARWMPKLEAYFHYRNLDVSTLKELCKRWRPEIAKGVVKRGKHEA
LADILESIEEMRYYREHFLKV

Sequences:

>Translated_181_residues
MAQDTNNLIWLDMEMTGLNPDQDRIIEVAMIVTDSNLNVLAESPVLVIHQPDAILDGMDDWNKNTHGKSGLIEKVKNSTV
SEAEAEQLLLEFMMQHVPERATPMCGNTIHQDRRFMARWMPKLEAYFHYRNLDVSTLKELCKRWRPEIAKGVVKRGKHEA
LADILESIEEMRYYREHFLKV
>Mature_180_residues
AQDTNNLIWLDMEMTGLNPDQDRIIEVAMIVTDSNLNVLAESPVLVIHQPDAILDGMDDWNKNTHGKSGLIEKVKNSTVS
EAEAEQLLLEFMMQHVPERATPMCGNTIHQDRRFMARWMPKLEAYFHYRNLDVSTLKELCKRWRPEIAKGVVKRGKHEAL
ADILESIEEMRYYREHFLKV

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=180, Percent_Identity=47.7777777777778, Blast_Score=187, Evalue=6e-48,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=59.6685082872928, Blast_Score=242, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17557752, Length=172, Percent_Identity=44.7674418604651, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323088, Length=187, Percent_Identity=36.3636363636364, Blast_Score=120, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21355135, Length=175, Percent_Identity=44, Blast_Score=174, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_CHRVO (Q7NVH5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_902038.1
- ProteinModelPortal:   Q7NVH5
- SMR:   Q7NVH5
- GeneID:   2548410
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2368
- NMPDR:   fig|243365.1.peg.2368
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   Q7NVH5
- ProtClustDB:   PRK05359
- BioCyc:   CVIO243365:CV_2368-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21050; Mature: 20918

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDTNNLIWLDMEMTGLNPDQDRIIEVAMIVTDSNLNVLAESPVLVIHQPDAILDGMDD
CCCCCCCEEEEEEEECCCCCCHHHHEEEEEEEECCCCCEEECCCEEEEECCHHHHCCCHH
WNKNTHGKSGLIEKVKNSTVSEAEAEQLLLEFMMQHVPERATPMCGNTIHQDRRFMARWM
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
PKLEAYFHYRNLDVSTLKELCKRWRPEIAKGVVKRGKHEALADILESIEEMRYYREHFLK
HHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
V
C
>Mature Secondary Structure 
AQDTNNLIWLDMEMTGLNPDQDRIIEVAMIVTDSNLNVLAESPVLVIHQPDAILDGMDD
CCCCCCEEEEEEEECCCCCCHHHHEEEEEEEECCCCCEEECCCEEEEECCHHHHCCCHH
WNKNTHGKSGLIEKVKNSTVSEAEAEQLLLEFMMQHVPERATPMCGNTIHQDRRFMARWM
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
PKLEAYFHYRNLDVSTLKELCKRWRPEIAKGVVKRGKHEALADILESIEEMRYYREHFLK
HHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782