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The map label for this gene is 34497781

Identifier: 34497781

GI number: 34497781

Start: 2518038

End: 2518946

Strand: Reverse

Name: 34497781

Synonym: CV_2326

Alternate gene names: NA

Gene position: 2518946-2518038 (Counterclockwise)

Preceding gene: 34497782

Following gene: 34497780

Centisome position: 53.02

GC content: 68.65

Gene sequence:

>909_bases
ATGCGCATCTATCGCACCGACCAGTTTCCGCTGCCGCTGCCCGCCGGCCACCGCTTCCCGGCGGAAAAATACCGGCTGCT
GGCCGAGCAGGTGTCGGCCTTCGCCGCCGAGCGCATGGAAACCGCGCCGGCGGCGACGCGCGGCGAGCTGATCCACGCCC
ACCATCCGGATTACGTCGACGCCGTGCTGAATGGCACGTTGGACGCGCGCGCCCAGAGGGAGATCGGCCTGCCATGGTCG
CCGGAGTTGGCCGAACGCAGCCGCCGCTCGGTGGGCGCCACCGTGGCCGCCAGTCGATCGGCCCTGCTGGAAGGTTGCGG
CGTGAACCTCGCGGGCGGAACCCACCACGCGGGCCGGGAACGCGGCAGCGGCTTTTGCATGTTCAATGACATCGCCGTCG
CATCGATGCTGCTGCTGGCGGAAGCGCGTGTCCGGCGCGTGCTGATAGTGGACCTGGACGTTCACCAAGGCGACGGCACC
GCCGCCATCGCCGCGGACGAGCCTCGCATCTTTACCTTTTCCATGCACGGCGCGCGCAATTTCCCGTTCCGCCGCGTCGA
CAGCGATTGGGACATCGACCTGCCCGACGGCACCGAAGACGCCGCCTATCTCGACGCGCTGGCGCGCGCGCTGCCGGAAC
TGTTCGCCCGCGCCCGTCCCGACCTGGTGTGTTACCTGGCCGGCGCCGACCCCTACCACGGCGACCGCCTGGGCCGCCTG
GCCCTCAGCAAGCAGGGGTTGGCCGAGCGGGACCGAATGGTGATGGAGGCCTGCCGCCGCTACGACGCCGCGCTGGCGGT
GACCATGGCAGGCGGCTATTCGGTGCCGATCACGGATACGGTGACAATACAGACCGAAACGGTCAGACTGGCGTGTGAGA
TTTTCGGCTCGTCCCCGACCAATCATTAA

Upstream 100 bases:

>100_bases
CTTATGGGCGCGCCCCGCCGCCATGTTCGCAGAAACGGTGGAGCACGAAGGCCGGCAAGTGCCGCGCTTTGCCCTGGTGA
AGGCGCTGTAGGCGGGCGCG

Downstream 100 bases:

>100_bases
GCTCGCGGGCGCGGGCGCCGTCGCCCGCATCCGGACCAGGTCCGCGAGTCCGAGCTGAGCGCGGCGGAAAGGCAAGGCCT
GACGCTGGCCGCGCCAAACC

Product: histone deacetylase/AcuC/AphA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRIYRTDQFPLPLPAGHRFPAEKYRLLAEQVSAFAAERMETAPAATRGELIHAHHPDYVDAVLNGTLDARAQREIGLPWS
PELAERSRRSVGATVAASRSALLEGCGVNLAGGTHHAGRERGSGFCMFNDIAVASMLLLAEARVRRVLIVDLDVHQGDGT
AAIAADEPRIFTFSMHGARNFPFRRVDSDWDIDLPDGTEDAAYLDALARALPELFARARPDLVCYLAGADPYHGDRLGRL
ALSKQGLAERDRMVMEACRRYDAALAVTMAGGYSVPITDTVTIQTETVRLACEIFGSSPTNH

Sequences:

>Translated_302_residues
MRIYRTDQFPLPLPAGHRFPAEKYRLLAEQVSAFAAERMETAPAATRGELIHAHHPDYVDAVLNGTLDARAQREIGLPWS
PELAERSRRSVGATVAASRSALLEGCGVNLAGGTHHAGRERGSGFCMFNDIAVASMLLLAEARVRRVLIVDLDVHQGDGT
AAIAADEPRIFTFSMHGARNFPFRRVDSDWDIDLPDGTEDAAYLDALARALPELFARARPDLVCYLAGADPYHGDRLGRL
ALSKQGLAERDRMVMEACRRYDAALAVTMAGGYSVPITDTVTIQTETVRLACEIFGSSPTNH
>Mature_302_residues
MRIYRTDQFPLPLPAGHRFPAEKYRLLAEQVSAFAAERMETAPAATRGELIHAHHPDYVDAVLNGTLDARAQREIGLPWS
PELAERSRRSVGATVAASRSALLEGCGVNLAGGTHHAGRERGSGFCMFNDIAVASMLLLAEARVRRVLIVDLDVHQGDGT
AAIAADEPRIFTFSMHGARNFPFRRVDSDWDIDLPDGTEDAAYLDALARALPELFARARPDLVCYLAGADPYHGDRLGRL
ALSKQGLAERDRMVMEACRRYDAALAVTMAGGYSVPITDTVTIQTETVRLACEIFGSSPTNH

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=197, Percent_Identity=32.994923857868, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI209862883, Length=197, Percent_Identity=32.994923857868, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI13128862, Length=254, Percent_Identity=27.5590551181102, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI13128860, Length=232, Percent_Identity=28.8793103448276, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI13128864, Length=178, Percent_Identity=32.5842696629214, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI293336691, Length=232, Percent_Identity=30.1724137931034, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI8923769, Length=201, Percent_Identity=29.3532338308458, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI20070354, Length=279, Percent_Identity=26.5232974910394, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193207430, Length=279, Percent_Identity=27.9569892473118, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17508561, Length=253, Percent_Identity=29.6442687747036, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561978, Length=210, Percent_Identity=30.4761904761905, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17534739, Length=210, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=197, Percent_Identity=26.3959390862944, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25154020, Length=213, Percent_Identity=25.8215962441315, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25154022, Length=206, Percent_Identity=27.6699029126214, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193206283, Length=235, Percent_Identity=25.9574468085106, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540332, Length=235, Percent_Identity=25.9574468085106, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321244, Length=291, Percent_Identity=27.1477663230241, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323999, Length=286, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=176, Percent_Identity=30.6818181818182, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=180, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649807, Length=208, Percent_Identity=36.0576923076923, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24657891, Length=233, Percent_Identity=30.4721030042918, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644244, Length=180, Percent_Identity=31.1111111111111, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281360899, Length=208, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642142, Length=208, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642144, Length=208, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642146, Length=208, Percent_Identity=28.8461538461538, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32942; Mature: 32942

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIYRTDQFPLPLPAGHRFPAEKYRLLAEQVSAFAAERMETAPAATRGELIHAHHPDYVD
CCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHH
AVLNGTLDARAQREIGLPWSPELAERSRRSVGATVAASRSALLEGCGVNLAGGTHHAGRE
HHHCCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RGSGFCMFNDIAVASMLLLAEARVRRVLIVDLDVHQGDGTAAIAADEPRIFTFSMHGARN
CCCCEEEEHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCEEEECCCCEEEEEEECCCCC
FPFRRVDSDWDIDLPDGTEDAAYLDALARALPELFARARPDLVCYLAGADPYHGDRLGRL
CCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
ALSKQGLAERDRMVMEACRRYDAALAVTMAGGYSVPITDTVTIQTETVRLACEIFGSSPT
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCEEEEEEEHHEEEEEEEECCCCC
NH
CC
>Mature Secondary Structure
MRIYRTDQFPLPLPAGHRFPAEKYRLLAEQVSAFAAERMETAPAATRGELIHAHHPDYVD
CCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHH
AVLNGTLDARAQREIGLPWSPELAERSRRSVGATVAASRSALLEGCGVNLAGGTHHAGRE
HHHCCCCCCHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RGSGFCMFNDIAVASMLLLAEARVRRVLIVDLDVHQGDGTAAIAADEPRIFTFSMHGARN
CCCCEEEEHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCEEEECCCCEEEEEEECCCCC
FPFRRVDSDWDIDLPDGTEDAAYLDALARALPELFARARPDLVCYLAGADPYHGDRLGRL
CCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
ALSKQGLAERDRMVMEACRRYDAALAVTMAGGYSVPITDTVTIQTETVRLACEIFGSSPT
HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCEEEEEEEHHEEEEEEEECCCCC
NH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]