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The map label for this gene is rnhB

Identifier: 34497665

GI number: 34497665

Start: 2380982

End: 2381578

Strand: Direct

Name: rnhB

Synonym: CV_2210

Alternate gene names: 34497665

Gene position: 2380982-2381578 (Clockwise)

Preceding gene: 34497664

Following gene: 34497666

Centisome position: 50.11

GC content: 69.35

Gene sequence:

>597_bases
ATGCCATTGAAGCTGCGGGTGGCGGGCGTGGACGAGGCGGGCCGCGGTCCGCTGGCCGGCGCCGTGTTCGCCGCCGCCGT
CATCCTGGATCCGGCCAAACCGATCGCCGGGCTTGCCGACTCCAAGGTGTTGAGCGAGGCGCAACGCGACGAGCTTGCCG
TCTTGATCAAGCGGGACGCGCTGGCCTGGTGCGTCGCCAGCGCCAGCGTCGAAGAAATCGACAAGCTCAACATCCTGCAC
GCCACCATGCTGGCCATGACGCGAGCGGTGGAGGGGTTGCCGGTGAGGCCGGATCTCGCCCAGATAGACGGCAACCGCGT
GCCCAAGCATCTGCCGGTGCCGGGCGAGGCCATCGTCAAGGGCGACGCCAAGGTGGCGGCCATCTCCGCCGCCTCCATCC
TGGCCAAGACCGCGCGCGACGCCGAGCTGGTGGCGCTGGATGCGCTCCATCCCCAATACGGTTTCGCCCGCCACAAAGGC
TATCCCACCGCCGAGCACCTGGCCGCCATCGAGGCGCATGGCGTGCTGCCTGCGCACCGCAAGACCTTCGGGCCGGTCAA
GGCCTGGCTGGCCAGCCACCAGGGCGCCTTGTTCTAG

Upstream 100 bases:

>100_bases
CGGCCAGGGCCGACATGGAAAAGGCGTTCACCGAACTGCACCTGGCCTTGAAGCAGGATACGGCCACCCGCGCCGCGCGC
GCGGTGCTGGAGGTGGCGCG

Downstream 100 bases:

>100_bases
CATGGCGGAGCAGGACGGCAAACGCTGTTTCCCGCCGGTGGCGGATGGCGATACCCGGTTGCTGATCCTGGGCTCGCTGC
CCGGCGATGCCTCGCTGGCG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MPLKLRVAGVDEAGRGPLAGAVFAAAVILDPAKPIAGLADSKVLSEAQRDELAVLIKRDALAWCVASASVEEIDKLNILH
ATMLAMTRAVEGLPVRPDLAQIDGNRVPKHLPVPGEAIVKGDAKVAAISAASILAKTARDAELVALDALHPQYGFARHKG
YPTAEHLAAIEAHGVLPAHRKTFGPVKAWLASHQGALF

Sequences:

>Translated_198_residues
MPLKLRVAGVDEAGRGPLAGAVFAAAVILDPAKPIAGLADSKVLSEAQRDELAVLIKRDALAWCVASASVEEIDKLNILH
ATMLAMTRAVEGLPVRPDLAQIDGNRVPKHLPVPGEAIVKGDAKVAAISAASILAKTARDAELVALDALHPQYGFARHKG
YPTAEHLAAIEAHGVLPAHRKTFGPVKAWLASHQGALF
>Mature_197_residues
PLKLRVAGVDEAGRGPLAGAVFAAAVILDPAKPIAGLADSKVLSEAQRDELAVLIKRDALAWCVASASVEEIDKLNILHA
TMLAMTRAVEGLPVRPDLAQIDGNRVPKHLPVPGEAIVKGDAKVAAISAASILAKTARDAELVALDALHPQYGFARHKGY
PTAEHLAAIEAHGVLPAHRKTFGPVKAWLASHQGALF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=184, Percent_Identity=64.1304347826087, Blast_Score=224, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_CHRVO (Q7NPS3)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901880.1
- ProteinModelPortal:   Q7NPS3
- SMR:   Q7NPS3
- GeneID:   2549461
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2210
- NMPDR:   fig|243365.1.peg.2210
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q7NPS3
- ProtClustDB:   PRK00015
- BioCyc:   CVIO243365:CV_2210-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 20736; Mature: 20605

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKLRVAGVDEAGRGPLAGAVFAAAVILDPAKPIAGLADSKVLSEAQRDELAVLIKRDA
CCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEHHHHH
LAWCVASASVEEIDKLNILHATMLAMTRAVEGLPVRPDLAQIDGNRVPKHLPVPGEAIVK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCEEEE
GDAKVAAISAASILAKTARDAELVALDALHPQYGFARHKGYPTAEHLAAIEAHGVLPAHR
CCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCHH
KTFGPVKAWLASHQGALF
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PLKLRVAGVDEAGRGPLAGAVFAAAVILDPAKPIAGLADSKVLSEAQRDELAVLIKRDA
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEEHHHHH
LAWCVASASVEEIDKLNILHATMLAMTRAVEGLPVRPDLAQIDGNRVPKHLPVPGEAIVK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCEEEE
GDAKVAAISAASILAKTARDAELVALDALHPQYGFARHKGYPTAEHLAAIEAHGVLPAHR
CCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCHH
KTFGPVKAWLASHQGALF
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782