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The map label for this gene is algC [H]

Identifier: 34497627

GI number: 34497627

Start: 2345191

End: 2346567

Strand: Reverse

Name: algC [H]

Synonym: CV_2172

Alternate gene names: 34497627

Gene position: 2346567-2345191 (Counterclockwise)

Preceding gene: 34497628

Following gene: 34497626

Centisome position: 49.39

GC content: 65.43

Gene sequence:

>1377_bases
ATGAACAAAATATCCAAAGACATCTTCAAGGCGTATGACATCCGCGGCATCGTCGGCAAGACCCTGACCGCCGCCGTCGC
TCGGCAAATCGGCCAAGCCGTGGCTTCGGAAGCCATTGACCGCAAGGTCAAGGCCATCGTGATCGGCCGCGACGGCCGCC
TGTCCGGCCCCGAATTGAGCGAGGCGCTGGCTGAAGGCATCCGCGCCGCCGGCGTCGACGTGATCGACGTCGGCCGCGTC
GCCACGCCCATGCTGTACTTCGCCGCCCATCAGCTGGGCACCCTGTCCGGCGTGATGGTGACCGGCAGCCACAATCCGCC
CGACTACAACGGCTTCAAGATGATGCTGGCCGGCGACACGCTGGCCGGCGACGACATCCAGGCGCTTTACCAGCGCATCG
TCGATGGCCGGCTCGCCGAGGGCGAAGGCGGCTATCGCACCGAAGACATCGCGGAAGCCTACCTGGAGCGCATCACCTCC
GACATCAAGCTTGAGCGTCCGCTGAACATCGTGGTGGACAGCGGCAACGGCGTGGCCGGCGCCTTCGGCCCGCTGCTGTA
CCGCCGCCTGGGCTGCAAGGTGCGCGAGCTGTTCTGCGACGTGGACGGCAATTTCCCCAACCACCACCCGGACCCGGCCA
AGCCGGAAAACCTGAAAGACCTGATCGAGGCGCTGCAGAAAACCGACGCCGAGATCGGCCTGGCCTTCGACGGCGACGGC
GACCGCCTGGGCGTGGTGACCAAGGACGGCAACATCATCTGGCCGGATCGCCAGCTGATGCTGTACGCCGCCGACGTGCT
GGACCGCAATCCCAAGGCCAAGGTGATCTTCGACGTCAAATCCACCCGGCTGCTCAAGCCCTGGATCAAGAAGAACGGCG
GCGTGCCGGTAATGGCGCGCACCGGCCACAGCTTCATCAAGGCCAAGATCAAGGAAACCGGCGCGCTGCTGGCCGGCGAG
ATGAGCGGCCACGTGTTCTTCAAGGAACGCTGGTACGGCTTCGACGACGGCATCTACACTGGCGCCCGCCTGCTGGAAGT
GCTGTCCCGCGTCGAGGATCCCAGCGAGCTCTTGAACGCGCTGCCCAACGCCGTCTCCACGCCAGAACTGAACCTGAAGA
TGGCCAAGGAGGGCGAGAACCACGCGCTGATCTCCAGGCTGCAGGAGTCCGCCAGCTTTGACGGCGCCGAGGAAGTGAAC
ACGCTGGACGGCCTGCGCGTCGAGTACAAGGACGGCTTCGGCCTGGCCCGCGCATCCAATACCACGCCGGTGATCGTGCT
GCGCTTCGAGGCCGACACCGAGGAGGCGCTGGAACGCATCAAGGGCGATTTCCGCCGCGTGCTGGCCACCGCCACCGACG
CCAAGCTGCCGTTCTAA

Upstream 100 bases:

>100_bases
ACTGCAGCAGCTGATCGCCTTGAGCCGAAAGCTCGGCGGCTGAATTCCCTGCGGGGCGGCGCACCTCCGCCCCCCAATCT
CATATCGCGTCAGAACCATC

Downstream 100 bases:

>100_bases
GCTTGCCGCGACCGGCGTTCGTTTGCAGATAGCTGTCAGGGGACATGGTGCATCCATGTCCCCGTTGCATTGAATTGAAA
GGAAATCCATGTACCAACTG

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNKISKDIFKAYDIRGIVGKTLTAAVARQIGQAVASEAIDRKVKAIVIGRDGRLSGPELSEALAEGIRAAGVDVIDVGRV
ATPMLYFAAHQLGTLSGVMVTGSHNPPDYNGFKMMLAGDTLAGDDIQALYQRIVDGRLAEGEGGYRTEDIAEAYLERITS
DIKLERPLNIVVDSGNGVAGAFGPLLYRRLGCKVRELFCDVDGNFPNHHPDPAKPENLKDLIEALQKTDAEIGLAFDGDG
DRLGVVTKDGNIIWPDRQLMLYAADVLDRNPKAKVIFDVKSTRLLKPWIKKNGGVPVMARTGHSFIKAKIKETGALLAGE
MSGHVFFKERWYGFDDGIYTGARLLEVLSRVEDPSELLNALPNAVSTPELNLKMAKEGENHALISRLQESASFDGAEEVN
TLDGLRVEYKDGFGLARASNTTPVIVLRFEADTEEALERIKGDFRRVLATATDAKLPF

Sequences:

>Translated_458_residues
MNKISKDIFKAYDIRGIVGKTLTAAVARQIGQAVASEAIDRKVKAIVIGRDGRLSGPELSEALAEGIRAAGVDVIDVGRV
ATPMLYFAAHQLGTLSGVMVTGSHNPPDYNGFKMMLAGDTLAGDDIQALYQRIVDGRLAEGEGGYRTEDIAEAYLERITS
DIKLERPLNIVVDSGNGVAGAFGPLLYRRLGCKVRELFCDVDGNFPNHHPDPAKPENLKDLIEALQKTDAEIGLAFDGDG
DRLGVVTKDGNIIWPDRQLMLYAADVLDRNPKAKVIFDVKSTRLLKPWIKKNGGVPVMARTGHSFIKAKIKETGALLAGE
MSGHVFFKERWYGFDDGIYTGARLLEVLSRVEDPSELLNALPNAVSTPELNLKMAKEGENHALISRLQESASFDGAEEVN
TLDGLRVEYKDGFGLARASNTTPVIVLRFEADTEEALERIKGDFRRVLATATDAKLPF
>Mature_458_residues
MNKISKDIFKAYDIRGIVGKTLTAAVARQIGQAVASEAIDRKVKAIVIGRDGRLSGPELSEALAEGIRAAGVDVIDVGRV
ATPMLYFAAHQLGTLSGVMVTGSHNPPDYNGFKMMLAGDTLAGDDIQALYQRIVDGRLAEGEGGYRTEDIAEAYLERITS
DIKLERPLNIVVDSGNGVAGAFGPLLYRRLGCKVRELFCDVDGNFPNHHPDPAKPENLKDLIEALQKTDAEIGLAFDGDG
DRLGVVTKDGNIIWPDRQLMLYAADVLDRNPKAKVIFDVKSTRLLKPWIKKNGGVPVMARTGHSFIKAKIKETGALLAGE
MSGHVFFKERWYGFDDGIYTGARLLEVLSRVEDPSELLNALPNAVSTPELNLKMAKEGENHALISRLQESASFDGAEEVN
TLDGLRVEYKDGFGLARASNTTPVIVLRFEADTEEALERIKGDFRRVLATATDAKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=459, Percent_Identity=34.640522875817, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1789566, Length=356, Percent_Identity=27.247191011236, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323934, Length=240, Percent_Identity=26.25, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 49880; Mature: 49880

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKISKDIFKAYDIRGIVGKTLTAAVARQIGQAVASEAIDRKVKAIVIGRDGRLSGPELS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
EALAEGIRAAGVDVIDVGRVATPMLYFAAHQLGTLSGVMVTGSHNPPDYNGFKMMLAGDT
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCC
LAGDDIQALYQRIVDGRLAEGEGGYRTEDIAEAYLERITSDIKLERPLNIVVDSGNGVAG
CCCHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHCEECCCCEEEEECCCCCCH
AFGPLLYRRLGCKVRELFCDVDGNFPNHHPDPAKPENLKDLIEALQKTDAEIGLAFDGDG
HHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
DRLGVVTKDGNIIWPDRQLMLYAADVLDRNPKAKVIFDVKSTRLLKPWIKKNGGVPVMAR
CEEEEEECCCCEECCCCCEEEEEHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEEC
TGHSFIKAKIKETGALLAGEMSGHVFFKERWYGFDDGIYTGARLLEVLSRVEDPSELLNA
CCCHHHHHHHHHHCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LPNAVSTPELNLKMAKEGENHALISRLQESASFDGAEEVNTLDGLRVEYKDGFGLARASN
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCEEECCC
TTPVIVLRFEADTEEALERIKGDFRRVLATATDAKLPF
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKISKDIFKAYDIRGIVGKTLTAAVARQIGQAVASEAIDRKVKAIVIGRDGRLSGPELS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
EALAEGIRAAGVDVIDVGRVATPMLYFAAHQLGTLSGVMVTGSHNPPDYNGFKMMLAGDT
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCC
LAGDDIQALYQRIVDGRLAEGEGGYRTEDIAEAYLERITSDIKLERPLNIVVDSGNGVAG
CCCHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHCEECCCCEEEEECCCCCCH
AFGPLLYRRLGCKVRELFCDVDGNFPNHHPDPAKPENLKDLIEALQKTDAEIGLAFDGDG
HHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
DRLGVVTKDGNIIWPDRQLMLYAADVLDRNPKAKVIFDVKSTRLLKPWIKKNGGVPVMAR
CEEEEEECCCCEECCCCCEEEEEHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEEC
TGHSFIKAKIKETGALLAGEMSGHVFFKERWYGFDDGIYTGARLLEVLSRVEDPSELLNA
CCCHHHHHHHHHHCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LPNAVSTPELNLKMAKEGENHALISRLQESASFDGAEEVNTLDGLRVEYKDGFGLARASN
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCEEECCC
TTPVIVLRFEADTEEALERIKGDFRRVLATATDAKLPF
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]