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The map label for this gene is nagZ

Identifier: 34497528

GI number: 34497528

Start: 2258209

End: 2259282

Strand: Direct

Name: nagZ

Synonym: CV_2073

Alternate gene names: 34497528

Gene position: 2258209-2259282 (Clockwise)

Preceding gene: 34497527

Following gene: 34497529

Centisome position: 47.53

GC content: 70.39

Gene sequence:

>1074_bases
TTGAATCTCCCGCGCGGCCCGGTGATGGTGGACATCGCCGGCTTCGCGCTGACCGAAGCGGAACGCGCCCGGCTGTCCCA
TCCGCTGGTCGGCGGCGTCATCCTGTTTCGCCGCAATTTCCACAACATCGAACAACTGCGCGCGCTGACCGCCGAGATCC
GCGCCTTGCGTACGCCGCATCTGTTGATCGCCGTCGATCACGAGGGCGGGCGCGTGCAGCGCTTCCTGGACGGCTTCACC
CGCCTGCCGCCGATGCGCGTGCTGGGCGAGGCCTGGGATGCCGACCGCGACCAGGCGCTGAAGCTGGCCGAGACTGTGGG
CTACGTGCTGGCGGCCGAATTGTCCGCCTGCGGCATAGACCTGTCCTTCACCCCGGTGCTGGACCTGGACTGGGAGCGTT
GCGCGGTGATCGGCAACCGCGCCTTCCACCGCGATCCGGAGGCGGTGTCGGCGCTGGCCGAAGCGCTGCAGCAAGGCCTG
GGCCGCGGCGGCATGATGAGCTGCGGCAAGCACTATCCCGGCCACGGCTATGTGGAGGGCGACAGCCACCATCTGATGCC
GCAGGACGATCGCACGCTGGCACAGATCGAACAGGACGATCTGGTGCCGTTCGCCCGTCTGGCCGACGCCGGCATGGGCG
CGGTGATGCCGGCCCACGTGCTGTACCCGGCGGTGGATAGCCAGCCGGCGGGCTTCTCCAAGGTGTGGCTGACCGACATC
CTGCGCGGCAGGATAGGCTTCGACGGCGTGATCTTCTCCGACGCGCTGGACATGGCCGGCGCGGCCGGCGCCGGCACTTA
CGTGCAGCGCGCCGACGCGGCGCTGGCCGCCGGCTGCGACATGGTGTTGGTGTGCAACCAGCCGGAAGAGGCGGACGCGA
TGCTGGCCGCGCTGGCGCCGCCGCCGCAACCCCAGCTGGCGGAGCGGCTGGAGCGCATGGCGGGCAAGAGCCGCGCCGAA
GATTGGCAGCGCTTGATCGCCACGCCGGATTTCGCCGCCGCGCAGGCGGCGGTCAGGCAATTGGCGATGCCCAAGGACGC
GCTGGCCGGGCCGCAAGTGGGCGAGGCGCACTGA

Upstream 100 bases:

>100_bases
GGACGCGGGAACGGTCGGCGCTCCGCGCCTGTCTTTAGCAATACCCGGGGTGGCCATGCCTGCCCCGATGGTCGAGGATG
AAACCATGAGCCAAACGACT

Downstream 100 bases:

>100_bases
GATGCTGCCCGCCAGCCTGCAAGAGCTGGACGCCATCCGCGACCAATGCCGGGCGATGGTGAACGGCCGGGCGGCGCTGT
CCGCCGGCGCGTCCGCCTTG

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNLPRGPVMVDIAGFALTEAERARLSHPLVGGVILFRRNFHNIEQLRALTAEIRALRTPHLLIAVDHEGGRVQRFLDGFT
RLPPMRVLGEAWDADRDQALKLAETVGYVLAAELSACGIDLSFTPVLDLDWERCAVIGNRAFHRDPEAVSALAEALQQGL
GRGGMMSCGKHYPGHGYVEGDSHHLMPQDDRTLAQIEQDDLVPFARLADAGMGAVMPAHVLYPAVDSQPAGFSKVWLTDI
LRGRIGFDGVIFSDALDMAGAAGAGTYVQRADAALAAGCDMVLVCNQPEEADAMLAALAPPPQPQLAERLERMAGKSRAE
DWQRLIATPDFAAAQAAVRQLAMPKDALAGPQVGEAH

Sequences:

>Translated_357_residues
MNLPRGPVMVDIAGFALTEAERARLSHPLVGGVILFRRNFHNIEQLRALTAEIRALRTPHLLIAVDHEGGRVQRFLDGFT
RLPPMRVLGEAWDADRDQALKLAETVGYVLAAELSACGIDLSFTPVLDLDWERCAVIGNRAFHRDPEAVSALAEALQQGL
GRGGMMSCGKHYPGHGYVEGDSHHLMPQDDRTLAQIEQDDLVPFARLADAGMGAVMPAHVLYPAVDSQPAGFSKVWLTDI
LRGRIGFDGVIFSDALDMAGAAGAGTYVQRADAALAAGCDMVLVCNQPEEADAMLAALAPPPQPQLAERLERMAGKSRAE
DWQRLIATPDFAAAQAAVRQLAMPKDALAGPQVGEAH
>Mature_357_residues
MNLPRGPVMVDIAGFALTEAERARLSHPLVGGVILFRRNFHNIEQLRALTAEIRALRTPHLLIAVDHEGGRVQRFLDGFT
RLPPMRVLGEAWDADRDQALKLAETVGYVLAAELSACGIDLSFTPVLDLDWERCAVIGNRAFHRDPEAVSALAEALQQGL
GRGGMMSCGKHYPGHGYVEGDSHHLMPQDDRTLAQIEQDDLVPFARLADAGMGAVMPAHVLYPAVDSQPAGFSKVWLTDI
LRGRIGFDGVIFSDALDMAGAAGAGTYVQRADAALAAGCDMVLVCNQPEEADAMLAALAPPPQPQLAERLERMAGKSRAE
DWQRLIATPDFAAAQAAVRQLAMPKDALAGPQVGEAH

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=337, Percent_Identity=45.1038575667656, Blast_Score=271, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_CHRVO (Q7NWB7)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901743.1
- ProteinModelPortal:   Q7NWB7
- SMR:   Q7NWB7
- GeneID:   2547871
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2073
- NMPDR:   fig|243365.1.peg.2073
- HOGENOM:   HBG617255
- OMA:   NEDIAPY
- PhylomeDB:   Q7NWB7
- ProtClustDB:   PRK05337
- BioCyc:   CVIO243365:CV_2073-MONOMER
- BRENDA:   3.2.1.52
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 38401; Mature: 38401

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 254-254

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPRGPVMVDIAGFALTEAERARLSHPLVGGVILFRRNFHNIEQLRALTAEIRALRTPH
CCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHEEHHCCCHHHHHHHHHHHHHHHCCCE
LLIAVDHEGGRVQRFLDGFTRLPPMRVLGEAWDADRDQALKLAETVGYVLAAELSACGID
EEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LSFTPVLDLDWERCAVIGNRAFHRDPEAVSALAEALQQGLGRGGMMSCGKHYPGHGYVEG
CCCCCEECCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECC
DSHHLMPQDDRTLAQIEQDDLVPFARLADAGMGAVMPAHVLYPAVDSQPAGFSKVWLTDI
CCCCCCCCCCCHHHHHCHHCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
LRGRIGFDGVIFSDALDMAGAAGAGTYVQRADAALAAGCDMVLVCNQPEEADAMLAALAP
HHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCC
PPQPQLAERLERMAGKSRAEDWQRLIATPDFAAAQAAVRQLAMPKDALAGPQVGEAH
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MNLPRGPVMVDIAGFALTEAERARLSHPLVGGVILFRRNFHNIEQLRALTAEIRALRTPH
CCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHEEHHCCCHHHHHHHHHHHHHHHCCCE
LLIAVDHEGGRVQRFLDGFTRLPPMRVLGEAWDADRDQALKLAETVGYVLAAELSACGID
EEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
LSFTPVLDLDWERCAVIGNRAFHRDPEAVSALAEALQQGLGRGGMMSCGKHYPGHGYVEG
CCCCCEECCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECC
DSHHLMPQDDRTLAQIEQDDLVPFARLADAGMGAVMPAHVLYPAVDSQPAGFSKVWLTDI
CCCCCCCCCCCHHHHHCHHCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
LRGRIGFDGVIFSDALDMAGAAGAGTYVQRADAALAAGCDMVLVCNQPEEADAMLAALAP
HHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCC
PPQPQLAERLERMAGKSRAEDWQRLIATPDFAAAQAAVRQLAMPKDALAGPQVGEAH
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782