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The map label for this gene is acpS

Identifier: 34497527

GI number: 34497527

Start: 2257707

End: 2258084

Strand: Direct

Name: acpS

Synonym: CV_2072

Alternate gene names: 34497527

Gene position: 2257707-2258084 (Clockwise)

Preceding gene: 34497526

Following gene: 34497528

Centisome position: 47.52

GC content: 67.72

Gene sequence:

>378_bases
ATGATTTACGGCATAGGCACCGACCTGGTGGAGATCGCCCGGATGGAGGCCTGGTGCCGGCGCTGGGGCGAGAAGGCGGG
GCGGCGGCTGCTGACCGCGGCGGAGCAGGCCGAGTTCGCGGCTCACGCCGAGCCGGCGCGCTTTCTCGCCAAGCGCTTCG
CCGCGAAGGAGGCTTTCGCCAAGGCGCTGGGCACCGGCGTGGTGGCGCCTGCCTTGCTGACGGCGATAGGCGTCGGCCAT
GATGAATTGGGCAAACCCGTGTTGATCTTGTCGGATGAACTGGCAGCCTTTGCCGCCGCGCGCGGCATTGCGCGCATGCA
TCTGTCCATCAGCGACGAGCGCGGCCACGCGCTGGCCTTCGTCGTGCTTGAATCGTAA

Upstream 100 bases:

>100_bases
GGCGCGTGGTCCATACCGAGTTCCTCTACGTATGGCTGCCGTGCCTCGCGTTGTGGGCGAGCCGATGCCTATGGCTGCGC
CGTTCGGCAGGGGCGCGCGC

Downstream 100 bases:

>100_bases
GGCGGGAGGCCGCCTCGCGCGCGAGGACGCGGGAACGGTCGGCGCTCCGCGCCTGTCTTTAGCAATACCCGGGGTGGCCA
TGCCTGCCCCGATGGTCGAG

Product: holo-ACP synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIYGIGTDLVEIARMEAWCRRWGEKAGRRLLTAAEQAEFAAHAEPARFLAKRFAAKEAFAKALGTGVVAPALLTAIGVGH
DELGKPVLILSDELAAFAAARGIARMHLSISDERGHALAFVVLES

Sequences:

>Translated_125_residues
MIYGIGTDLVEIARMEAWCRRWGEKAGRRLLTAAEQAEFAAHAEPARFLAKRFAAKEAFAKALGTGVVAPALLTAIGVGH
DELGKPVLILSDELAAFAAARGIARMHLSISDERGHALAFVVLES
>Mature_125_residues
MIYGIGTDLVEIARMEAWCRRWGEKAGRRLLTAAEQAEFAAHAEPARFLAKRFAAKEAFAKALGTGVVAPALLTAIGVGH
DELGKPVLILSDELAAFAAARGIARMHLSISDERGHALAFVVLES

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=124, Percent_Identity=49.1935483870968, Blast_Score=110, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CHRVO (Q7NWB8)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901742.1
- ProteinModelPortal:   Q7NWB8
- SMR:   Q7NWB8
- GeneID:   2547737
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2072
- NMPDR:   fig|243365.1.peg.2072
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q7NWB8
- ProtClustDB:   CLSK2485451
- BioCyc:   CVIO243365:CV_2072-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13355; Mature: 13355

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGIGTDLVEIARMEAWCRRWGEKAGRRLLTAAEQAEFAAHAEPARFLAKRFAAKEAFA
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KALGTGVVAPALLTAIGVGHDELGKPVLILSDELAAFAAARGIARMHLSISDERGHALAF
HHHCCCHHHHHHHHHHCCCHHHHCCCEEEECHHHHHHHHHHHHHHHEEEECCCCCCEEEE
VVLES
EEECC
>Mature Secondary Structure
MIYGIGTDLVEIARMEAWCRRWGEKAGRRLLTAAEQAEFAAHAEPARFLAKRFAAKEAFA
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KALGTGVVAPALLTAIGVGHDELGKPVLILSDELAAFAAARGIARMHLSISDERGHALAF
HHHCCCHHHHHHHHHHCCCHHHHCCCEEEECHHHHHHHHHHHHHHHEEEECCCCCCEEEE
VVLES
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782