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The map label for this gene is speA [H]

Identifier: 34497447

GI number: 34497447

Start: 2172175

End: 2173425

Strand: Direct

Name: speA [H]

Synonym: CV_1992

Alternate gene names: 34497447

Gene position: 2172175-2173425 (Clockwise)

Preceding gene: 34497443

Following gene: 34497448

Centisome position: 45.72

GC content: 65.47

Gene sequence:

>1251_bases
GTGATCTTCCAGACCCTGCTGGCGCCGGGCGACAAGCTGCTGCTGGATCGCAACTGTCACAAATCGGTCCACCACGGCGT
GATCCTGTCCGGCGCGCGGCCGGTATACCTGGACTCGTCGGTCAACCGCCAGTACGGGATTTTCGGGCCGGTGCCCAAGA
CCACGATTTACCAGGCGATAGACGACAATCCGGACGCGCGAGTGCTGATCCTCACCTCCTGCACCTACGACGGCCTGCGC
TACGACCTGAAGCCCATCATCGAGGCCGCGCACGAGAAGGGCATCAAGGTGATCGTCGACGAGGCCTGGTACGGCTTCGC
CCGCTTCCACCCCGCGTTCCGGCCGACGGCGCTGGAGTCCGGCGCGGACTACGTGACGCAGAGCACGCACAAGGTGCTGT
CGGCGTTCTCGCAGGCCAGCATGATCCACGTCAACGACCCGCGCTTCGACGAGCATTTGTTCCGAGAGAACTTCAACATG
CACGCGTCCACCAGCCCTCAGTACAGCCTGATCGCCAGCCTGGACGTGGCGCGCAAGCAGGCGGTGATGGAGGGCTACCG
CTTGTTGGACCGCACGCTGAAGCTGGCGCAGGAGCTGCGCGAGAAGATCAATTCCACCGGCGCCTTCCGCGTGCTGGAGC
TGGACGATCTGCTGCCGGAAGAGGTGAGGGAGGACGGCATCCTGCTGGATCCGACCAAGCTGACCGTGGACTTCAGCCGC
TCCGGCTTCACCGCCGACGAACTGCAGCAGGCGCTGTTCGAGCGTTACAACATTCAGGTGGAGAAGTCGACGTTCAGCAC
CATCACGCTGCTGCTGACCATCGGCACCACCCGCAGCAAGCTGTCCCGACTTTACGACGCGATGCTGAGGCTGGCCAAGG
AGGGCCGTGCGCCGCGGCCGCTGGGGCGCATGCCGGAGATTCCGCACTTCTCCCGGCTGGCCTGCCTGCCGCGCGACGCC
TTCTACGAGGCCGGCGAGCGCCTGCCGCTGCTGGACGACGACGGCCGGCCGAATCCGGCATTGAGCGGGCGGGTGTGCTG
CGACCAGATCGTGCCGTATCCGCCCGGCATCCCGGTGCTGGTGCCGGGGCAGGTGGTGGACGACACCATCCTGGCCTACC
TGGCGCGGCTGCAGAAAACGCAGAAGAGCATCGAGATGCACGGCTTGGCGGAGGATGGCGGCGAGTTTTACCTGCGGGTG
CTGAAGCCGCAGGAGCTGGCGGAATTGCCCGGCCGCAGTTTGTTCAATTGA

Upstream 100 bases:

>100_bases
TCCGACCGGCGTCATCGCCGAGTCGCAGATGCTGGCGGCCAAGGCCTTCGGCGCGCGCAAGACCTATTTCGCCACCAACG
GCACGTCCACGTCGAACAAG

Downstream 100 bases:

>100_bases
ATGCTTGTCAGGCAGGGGGATTTCCGATAAATATAACAAATGTCGCATTTCTGTAAATCATGACCATGTATTGGCAGGGG
CGCGACATTTGTAAAGTGAC

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MIFQTLLAPGDKLLLDRNCHKSVHHGVILSGARPVYLDSSVNRQYGIFGPVPKTTIYQAIDDNPDARVLILTSCTYDGLR
YDLKPIIEAAHEKGIKVIVDEAWYGFARFHPAFRPTALESGADYVTQSTHKVLSAFSQASMIHVNDPRFDEHLFRENFNM
HASTSPQYSLIASLDVARKQAVMEGYRLLDRTLKLAQELREKINSTGAFRVLELDDLLPEEVREDGILLDPTKLTVDFSR
SGFTADELQQALFERYNIQVEKSTFSTITLLLTIGTTRSKLSRLYDAMLRLAKEGRAPRPLGRMPEIPHFSRLACLPRDA
FYEAGERLPLLDDDGRPNPALSGRVCCDQIVPYPPGIPVLVPGQVVDDTILAYLARLQKTQKSIEMHGLAEDGGEFYLRV
LKPQELAELPGRSLFN

Sequences:

>Translated_416_residues
MIFQTLLAPGDKLLLDRNCHKSVHHGVILSGARPVYLDSSVNRQYGIFGPVPKTTIYQAIDDNPDARVLILTSCTYDGLR
YDLKPIIEAAHEKGIKVIVDEAWYGFARFHPAFRPTALESGADYVTQSTHKVLSAFSQASMIHVNDPRFDEHLFRENFNM
HASTSPQYSLIASLDVARKQAVMEGYRLLDRTLKLAQELREKINSTGAFRVLELDDLLPEEVREDGILLDPTKLTVDFSR
SGFTADELQQALFERYNIQVEKSTFSTITLLLTIGTTRSKLSRLYDAMLRLAKEGRAPRPLGRMPEIPHFSRLACLPRDA
FYEAGERLPLLDDDGRPNPALSGRVCCDQIVPYPPGIPVLVPGQVVDDTILAYLARLQKTQKSIEMHGLAEDGGEFYLRV
LKPQELAELPGRSLFN
>Mature_416_residues
MIFQTLLAPGDKLLLDRNCHKSVHHGVILSGARPVYLDSSVNRQYGIFGPVPKTTIYQAIDDNPDARVLILTSCTYDGLR
YDLKPIIEAAHEKGIKVIVDEAWYGFARFHPAFRPTALESGADYVTQSTHKVLSAFSQASMIHVNDPRFDEHLFRENFNM
HASTSPQYSLIASLDVARKQAVMEGYRLLDRTLKLAQELREKINSTGAFRVLELDDLLPEEVREDGILLDPTKLTVDFSR
SGFTADELQQALFERYNIQVEKSTFSTITLLLTIGTTRSKLSRLYDAMLRLAKEGRAPRPLGRMPEIPHFSRLACLPRDA
FYEAGERLPLLDDDGRPNPALSGRVCCDQIVPYPPGIPVLVPGQVVDDTILAYLARLQKTQKSIEMHGLAEDGGEFYLRV
LKPQELAELPGRSLFN

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=494, Percent_Identity=27.3279352226721, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1790573, Length=486, Percent_Identity=27.7777777777778, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786384, Length=488, Percent_Identity=28.6885245901639, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786909, Length=493, Percent_Identity=26.7748478701826, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082193, Length=492, Percent_Identity=27.2357723577236, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 46725; Mature: 46725

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFQTLLAPGDKLLLDRNCHKSVHHGVILSGARPVYLDSSVNRQYGIFGPVPKTTIYQAI
CCCHHHHCCCCEEEECCCHHHHHHCCEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHH
DDNPDARVLILTSCTYDGLRYDLKPIIEAAHEKGIKVIVDEAWYGFARFHPAFRPTALES
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCHHHHC
GADYVTQSTHKVLSAFSQASMIHVNDPRFDEHLFRENFNMHASTSPQYSLIASLDVARKQ
CCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHH
AVMEGYRLLDRTLKLAQELREKINSTGAFRVLELDDLLPEEVREDGILLDPTKLTVDFSR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHCCCEEECCCEEEEEECC
SGFTADELQQALFERYNIQVEKSTFSTITLLLTIGTTRSKLSRLYDAMLRLAKEGRAPRP
CCCCHHHHHHHHHHHHCCEEECCHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
LGRMPEIPHFSRLACLPRDAFYEAGERLPLLDDDGRPNPALSGRVCCDQIVPYPPGIPVL
CCCCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEE
VPGQVVDDTILAYLARLQKTQKSIEMHGLAEDGGEFYLRVLKPQELAELPGRSLFN
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHCCCCCCCC
>Mature Secondary Structure
MIFQTLLAPGDKLLLDRNCHKSVHHGVILSGARPVYLDSSVNRQYGIFGPVPKTTIYQAI
CCCHHHHCCCCEEEECCCHHHHHHCCEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHH
DDNPDARVLILTSCTYDGLRYDLKPIIEAAHEKGIKVIVDEAWYGFARFHPAFRPTALES
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCHHHHC
GADYVTQSTHKVLSAFSQASMIHVNDPRFDEHLFRENFNMHASTSPQYSLIASLDVARKQ
CCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHH
AVMEGYRLLDRTLKLAQELREKINSTGAFRVLELDDLLPEEVREDGILLDPTKLTVDFSR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHCCCEEECCCEEEEEECC
SGFTADELQQALFERYNIQVEKSTFSTITLLLTIGTTRSKLSRLYDAMLRLAKEGRAPRP
CCCCHHHHHHHHHHHHCCEEECCHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCC
LGRMPEIPHFSRLACLPRDAFYEAGERLPLLDDDGRPNPALSGRVCCDQIVPYPPGIPVL
CCCCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEE
VPGQVVDDTILAYLARLQKTQKSIEMHGLAEDGGEFYLRVLKPQELAELPGRSLFN
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]