Click here to switch to the map view.

The map label for this gene is gsiC [H]

Identifier: 34497434

GI number: 34497434

Start: 2154823

End: 2155761

Strand: Direct

Name: gsiC [H]

Synonym: CV_1979

Alternate gene names: 34497434

Gene position: 2154823-2155761 (Clockwise)

Preceding gene: 34497433

Following gene: 34497435

Centisome position: 45.35

GC content: 60.81

Gene sequence:

>939_bases
ATGTCCGCATTCATCATCCGCCGGCTGCTGCAAATGATCCCGACCCTGTTCGGGGTGATGCTGCTGGTATTCATCCTGTT
CACGCTGGTGGGCGGCGATCCGTCGCTGGTGCTGGCCGGCAAGCATTTCTCGGCCGAGGTGCTGGCGCACATCCGCGCCC
AATTGGGTCTGGACAAGAGCCTGCCGGAACAATTTCTGTTGTTTGTCCATCAAGTGCTGACGCTGGACTTCGGCACTTCC
TGGTCCACCCAGCAGCCGGTGTCCGACATCATCGGCAGCCGCGTCGGGCCGTCGCTGACGCTGACCGGCGCCATGCTGGT
GGTCGATCTGCTGGTCGCCATTCCATTGGCGGCGCTGGTCGCGTACTTCCGCGGCGGCCTGACCGATCACATCGTCACCA
TTTCCTGCACCGTGGCCATGTCCATCAGCGCGCTGATCTACATCATCGCCGGCCAGTTTTTCCTCGGCTTCAAGCTGGGC
TGGTTTCCGGTGCGCGGCTGGGGGGATTCGTTCTGGGTCAATCTATTCGTCTACGTGCCGCTGCCCTTGCTGCTGGGCTT
GATGGTGTCGCTCGGACCGGACATCCGTTTCTATCGCAGCTTCTTCGTCGAGGAACTGGGCCAGGACTATGTGCGCACCG
CGCGGGCCAAAGGTTTGTCCGAACGCCAGATCATGCTGAAGCACGTGCTGCGCAACGCGCTGATTCCGGTGGTGACCAGC
GTGATGATGTCCTTGCCGTACATGTTGCTGGGCGCGCTGGTGCTGGAGAGCTTCTTCGGCATTCCCGGCATGGGCAACGA
GGTGGTGCAGGCGGTGAACAAGAGCGATTTCCCGGTGATCAAGGCCATCACCATCTATATCGCCATCGCCACCATGGTGT
TCAACCTGTTGGGCGACCTGGTCTACAAGTGGATCGATCCGCGCGTGCAACTGAAGTAA

Upstream 100 bases:

>100_bases
GCGCAGCCGTGGGTGAGGGGGTTCAAGCACCACCCCAACTTCAATGCCATCTGGCGTTTCCTGGACGTAGAAAAATAAGC
GGGGAGCGAGGAGAATCATC

Downstream 100 bases:

>100_bases
GCGGAGGAGAACAATCATGACGACATTGCAGAATACCGCCGGCGCCGCGCCGGCCGCGCCGTCCCGCAGCCTGTGGGGCC
TGGGATGGCAGCGCCTGAAG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSAFIIRRLLQMIPTLFGVMLLVFILFTLVGGDPSLVLAGKHFSAEVLAHIRAQLGLDKSLPEQFLLFVHQVLTLDFGTS
WSTQQPVSDIIGSRVGPSLTLTGAMLVVDLLVAIPLAALVAYFRGGLTDHIVTISCTVAMSISALIYIIAGQFFLGFKLG
WFPVRGWGDSFWVNLFVYVPLPLLLGLMVSLGPDIRFYRSFFVEELGQDYVRTARAKGLSERQIMLKHVLRNALIPVVTS
VMMSLPYMLLGALVLESFFGIPGMGNEVVQAVNKSDFPVIKAITIYIAIATMVFNLLGDLVYKWIDPRVQLK

Sequences:

>Translated_312_residues
MSAFIIRRLLQMIPTLFGVMLLVFILFTLVGGDPSLVLAGKHFSAEVLAHIRAQLGLDKSLPEQFLLFVHQVLTLDFGTS
WSTQQPVSDIIGSRVGPSLTLTGAMLVVDLLVAIPLAALVAYFRGGLTDHIVTISCTVAMSISALIYIIAGQFFLGFKLG
WFPVRGWGDSFWVNLFVYVPLPLLLGLMVSLGPDIRFYRSFFVEELGQDYVRTARAKGLSERQIMLKHVLRNALIPVVTS
VMMSLPYMLLGALVLESFFGIPGMGNEVVQAVNKSDFPVIKAITIYIAIATMVFNLLGDLVYKWIDPRVQLK
>Mature_311_residues
SAFIIRRLLQMIPTLFGVMLLVFILFTLVGGDPSLVLAGKHFSAEVLAHIRAQLGLDKSLPEQFLLFVHQVLTLDFGTSW
STQQPVSDIIGSRVGPSLTLTGAMLVVDLLVAIPLAALVAYFRGGLTDHIVTISCTVAMSISALIYIIAGQFFLGFKLGW
FPVRGWGDSFWVNLFVYVPLPLLLGLMVSLGPDIRFYRSFFVEELGQDYVRTARAKGLSERQIMLKHVLRNALIPVVTSV
MMSLPYMLLGALVLESFFGIPGMGNEVVQAVNKSDFPVIKAITIYIAIATMVFNLLGDLVYKWIDPRVQLK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=315, Percent_Identity=37.1428571428571, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=31.4705882352941, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789888, Length=315, Percent_Identity=31.7460317460317, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=34.5565749235474, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787497, Length=311, Percent_Identity=27.0096463022508, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788504, Length=369, Percent_Identity=26.0162601626016, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=23.0769230769231, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34469; Mature: 34338

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFIIRRLLQMIPTLFGVMLLVFILFTLVGGDPSLVLAGKHFSAEVLAHIRAQLGLDKS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCC
LPEQFLLFVHQVLTLDFGTSWSTQQPVSDIIGSRVGPSLTLTGAMLVVDLLVAIPLAALV
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AYFRGGLTDHIVTISCTVAMSISALIYIIAGQFFLGFKLGWFPVRGWGDSFWVNLFVYVP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHH
LPLLLGLMVSLGPDIRFYRSFFVEELGQDYVRTARAKGLSERQIMLKHVLRNALIPVVTS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VMMSLPYMLLGALVLESFFGIPGMGNEVVQAVNKSDFPVIKAITIYIAIATMVFNLLGDL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VYKWIDPRVQLK
HHHHCCCCCCCC
>Mature Secondary Structure 
SAFIIRRLLQMIPTLFGVMLLVFILFTLVGGDPSLVLAGKHFSAEVLAHIRAQLGLDKS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCC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HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA