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The map label for this gene is alr [H]

Identifier: 34497370

GI number: 34497370

Start: 2080591

End: 2081661

Strand: Direct

Name: alr [H]

Synonym: CV_1915

Alternate gene names: 34497370

Gene position: 2080591-2081661 (Clockwise)

Preceding gene: 34497369

Following gene: 34497372

Centisome position: 43.79

GC content: 69.47

Gene sequence:

>1071_bases
ATGCGTCCGTTGATCGCGACGATACGGCTGGACCATTTGCGGCATAACTATCTGCAAGCGCGCGCCGCCCACGGCGACCG
CGCGCTGGCGGTGCTGAAGGCCAACGCCTACGGCCATGGCGCGGTCCGTTGCGCCCAGGCGCTGGCCGACATCGCCGACG
GCTTCGCCGTCGCCTGCCTGGAGGAGGCGCTGGAGCTGCGCGCCGCCGGCATCGCCAACCCCATCCTGTTGCTGGAGGGC
GTGTTCGACGCCGAGGAACTGAAGGCGGTGGACGAGCATGGCCTGTGGATGGCGGTGACCAGCGAGGAGCAACTGAGCAT
GGTCGAGCAGTCGAATCCGTCGAGGCCGTTCAATGTCTGGCTGATGCTGGATTCCGGCATGCACCGCGAAGGCTTCCTGC
CGGAAAATTATCACCAGGCTTGGCATAGGCTGCAGGCCAGCGGCAAGGCGGGCGGCATCACCAAGATGACTCACTTCGCC
CGCGCCGACGAGCCTGAGATCCCGATGACCTTCGCGCAGCTGGAGGCGTTCGACGCCGCGGTGCGGGGCCTGCCGGCCGG
CGACGAGTCGGTCGCCAACTCGGCCGGCATCCTGTGCCACCCGCGCGCGCAGCGCAACTGGGGCCGCGTCGGCATCGCGC
TGTACGGCGTGACGCCGCTGCCGGCCGGATTCGGGCAGGGCGACGCGCTGCGCCCGGTGATGCGTTTCTCCAGCAAGGTG
TTCGGCGTGCGCGAGCTGGGCGTCGGCGAGCCCATCGGCTACGGCGACAACTTCGTCACCGAGCGCCCGACGCGCGTCGG
CCTGGTGGCCTGCGGCTACGCCGACGGCTACCCGCGGCGCGCTTCCAGCGGCAGTCCGGCGTTGGTGGATGGACAGCGCA
CGCGGCTGATCGGCCGGGTGTCGATGGACATGCTGACCGTGGATCTGACCGATCTGCCGGCAGTCGGCGTCGGCAGCGAG
GTCGAGCTGTGGGGGGACGGCGTGTCGGTCAACGAGGTGGCGGCCCACGCCGGCACCATAGGCTACGAGCCCTTGTGCAA
CGTCAAGCGCGCGCGCTTCGTCTACCGTTGA

Upstream 100 bases:

>100_bases
GGAAATCAGCGTCGACGGCCTGTCGATGCAGCGTTACGCCAAGCAGGGCGAAACCCTGGTGGTGCCGGTGATTCGTCCCG
CGGTGCAAGGGGCCTGAAGC

Downstream 100 bases:

>100_bases
CGGCAGCGTTGTTCACGAAAAAGCCCGGCCATGAGCCGGGCTTTTGCTTTGGCAAATAGATGGGTTCAGTCGCGCTGCGC
CACCAGCTTTTCCACTCTTT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRPLIATIRLDHLRHNYLQARAAHGDRALAVLKANAYGHGAVRCAQALADIADGFAVACLEEALELRAAGIANPILLLEG
VFDAEELKAVDEHGLWMAVTSEEQLSMVEQSNPSRPFNVWLMLDSGMHREGFLPENYHQAWHRLQASGKAGGITKMTHFA
RADEPEIPMTFAQLEAFDAAVRGLPAGDESVANSAGILCHPRAQRNWGRVGIALYGVTPLPAGFGQGDALRPVMRFSSKV
FGVRELGVGEPIGYGDNFVTERPTRVGLVACGYADGYPRRASSGSPALVDGQRTRLIGRVSMDMLTVDLTDLPAVGVGSE
VELWGDGVSVNEVAAHAGTIGYEPLCNVKRARFVYR

Sequences:

>Translated_356_residues
MRPLIATIRLDHLRHNYLQARAAHGDRALAVLKANAYGHGAVRCAQALADIADGFAVACLEEALELRAAGIANPILLLEG
VFDAEELKAVDEHGLWMAVTSEEQLSMVEQSNPSRPFNVWLMLDSGMHREGFLPENYHQAWHRLQASGKAGGITKMTHFA
RADEPEIPMTFAQLEAFDAAVRGLPAGDESVANSAGILCHPRAQRNWGRVGIALYGVTPLPAGFGQGDALRPVMRFSSKV
FGVRELGVGEPIGYGDNFVTERPTRVGLVACGYADGYPRRASSGSPALVDGQRTRLIGRVSMDMLTVDLTDLPAVGVGSE
VELWGDGVSVNEVAAHAGTIGYEPLCNVKRARFVYR
>Mature_356_residues
MRPLIATIRLDHLRHNYLQARAAHGDRALAVLKANAYGHGAVRCAQALADIADGFAVACLEEALELRAAGIANPILLLEG
VFDAEELKAVDEHGLWMAVTSEEQLSMVEQSNPSRPFNVWLMLDSGMHREGFLPENYHQAWHRLQASGKAGGITKMTHFA
RADEPEIPMTFAQLEAFDAAVRGLPAGDESVANSAGILCHPRAQRNWGRVGIALYGVTPLPAGFGQGDALRPVMRFSSKV
FGVRELGVGEPIGYGDNFVTERPTRVGLVACGYADGYPRRASSGSPALVDGQRTRLIGRVSMDMLTVDLTDLPAVGVGSE
VELWGDGVSVNEVAAHAGTIGYEPLCNVKRARFVYR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=352, Percent_Identity=44.6022727272727, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1790487, Length=350, Percent_Identity=45.1428571428571, Blast_Score=275, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38396; Mature: 38396

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLIATIRLDHLRHNYLQARAAHGDRALAVLKANAYGHGAVRCAQALADIADGFAVACL
CCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHH
EEALELRAAGIANPILLLEGVFDAEELKAVDEHGLWMAVTSEEQLSMVEQSNPSRPFNVW
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCEEEE
LMLDSGMHREGFLPENYHQAWHRLQASGKAGGITKMTHFARADEPEIPMTFAQLEAFDAA
EEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VRGLPAGDESVANSAGILCHPRAQRNWGRVGIALYGVTPLPAGFGQGDALRPVMRFSSKV
HHCCCCCCHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
FGVRELGVGEPIGYGDNFVTERPTRVGLVACGYADGYPRRASSGSPALVDGQRTRLIGRV
CCHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCHHEEEEEE
SMDMLTVDLTDLPAVGVGSEVELWGDGVSVNEVAAHAGTIGYEPLCNVKRARFVYR
EEEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHCCHHHHHCCCC
>Mature Secondary Structure
MRPLIATIRLDHLRHNYLQARAAHGDRALAVLKANAYGHGAVRCAQALADIADGFAVACL
CCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHH
EEALELRAAGIANPILLLEGVFDAEELKAVDEHGLWMAVTSEEQLSMVEQSNPSRPFNVW
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCEEEE
LMLDSGMHREGFLPENYHQAWHRLQASGKAGGITKMTHFARADEPEIPMTFAQLEAFDAA
EEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VRGLPAGDESVANSAGILCHPRAQRNWGRVGIALYGVTPLPAGFGQGDALRPVMRFSSKV
HHCCCCCCHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
FGVRELGVGEPIGYGDNFVTERPTRVGLVACGYADGYPRRASSGSPALVDGQRTRLIGRV
CCHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCHHEEEEEE
SMDMLTVDLTDLPAVGVGSEVELWGDGVSVNEVAAHAGTIGYEPLCNVKRARFVYR
EEEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA