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The map label for this gene is shlB [H]

Identifier: 34497372

GI number: 34497372

Start: 2083216

End: 2084916

Strand: Direct

Name: shlB [H]

Synonym: CV_1917

Alternate gene names: 34497372

Gene position: 2083216-2084916 (Clockwise)

Preceding gene: 34497370

Following gene: 34497373

Centisome position: 43.85

GC content: 68.25

Gene sequence:

>1701_bases
ATGCGGAGCCGGGAAACATACGCCGTGAACAAACGCCTCCCCATCGTCGTGGCCGCATGGCTGGCCTGCTGCCAGTCGGC
CCTGGCCGATTCCCTGCCGCCGCAGGCTGAGCATGACGGCGCCGACGCGCGTCGCCTGTTGCAGGACAGCGACCGCCGTT
TCGACAATCTGATCCAGCAGCAAAGGATGCGCCAGCTGAAAAGCGAAGGCAGCAATCTGGAGGCGGAACGCGCGCCTCAG
ATGGAGGGGGGGAGCTGCCTGCCGGTCAGCGGTCTGAAGCTGGCCGGCATCAGGCTGTTGTCGCGGGAGGAGGTGACGGC
GCTCGGCCCGCCGCGCGGAACCTGCCTGGACATCGCGGAGCTCAACCGCTTCAGCCGGGCGTTGACCGCCTTGTACCTGG
AGCGCGGCTTCATCGCCGCAAGGGTGAGGCCGGAAGGGCCCGACGCCGACGGCGCGCTGACGCTGAGGGTGGTGGAGGGC
AAGGTGGCGGCGATACGCGGCGACGCGGACGCGCCCAAGGCCGGCAACCTGTTTCCCGGCATGCTGGGCAAGCCTTTGAA
CGTGCATGATCTGGACCAGGGCCTGGATCAGGCCAACCGGCTGCGTTCCAACAAGGTGACTGTCGACGTGCTGCCCGGCG
ATGCCGCGGGCGAATCGGCGCTGCAGCTGCATAACCAGCCCGCTGTCCGGCTGTCCGGCGGACTGTCGCTGGACAACGCC
GGACGGGACAGCACCGGCCGCATGCAGGCGGGCGCCAGCCTGAACTGGGACAATCCGGCCGACTGGAGCGATCTGCTCAA
CCTGTCGGTCCAGACCACCACCGCGCGGCAAGAGATCCGGCACAGCCGCAGCGAGTCGCTGTTCTATTCCCTGCCTTACG
GCTACTGGACATTGAGCGCCTTCGCCAGCCATGCCGACTACCTGATACCCAATACCCTGCAGTCGGGCTTGGTGGTGCAG
TTGTCCGGCACCACCGAACAGAACGGCTTGCGGCTGGACAGGGTGTTGTCGCGCGGGCAGAACCATGTGCTGACCGCCGA
CGCGCAGCTGGTGCAGAAACGAGTGCGCAACTTTTTCCAGGATGTGCGTTTGGATAGCAGCATGAACCTGACAGTTCTGG
AGGCCGGCGTGTCGCAACTGCTGATCCAGCCCGCCGGCCTGCTGCAGCTGGACGGCAGCGTGCAGCGCGGCGTGCGCTGG
CTGGGCGCGGATGCGCCGGATCCGCTGCATCCGGGCGCCGCCAATCCGCAATTCACCAAGCTGAGGCTGGGTCTTGCCTG
GTTCCGCGGGCTGGCGCTGCCCGGCGGCCCTTATCAGTTGCAGATCGCCTTGTCCGGCCAGGCCAGCCGCGACGAGTTGC
CCGGCGTCGAGCGGCTGGACATCGCCGACGCCAGCGCGGTGCGCGGCTTCCGCAACAACTCGCTGGTGTCGGAAACCGGC
TGGTATTGGCGCAACACCCTGTCCCGCCGCTTCATGGCGGGCGGCTGGAGCCTGACGCCGCGCGTGGGCGTGGACGGCGG
TCGGGTGCTGCAGCGGGACGCACGGGAAACCTGGCAGGACATCGCCGGCGCGGCGGTCGGCCTGGCGTTGGCGCGGGGCG
GGCTGACGCTGGACCTCGACTACAGCCGGCCCTTGCGCAAGCCGCAGGGCTGGCTATCGGAGGGCCACATCCTGTTCGCC
CGGCTCAACTGGCAGTGGTAA

Upstream 100 bases:

>100_bases
ATACGGCGCTTGCCGCGGGCGGGAATGTGGGACGCTGCCCGGGATATTCATTTGTGGTTTAATGGGCGGCTTTGATTTTT
AAGACCGATCCTACCCTCCG

Downstream 100 bases:

>100_bases
GCGCTGGTGTTGTAAATGAAACGAAAAAATTATTCACATCATTGCAAACGAGTATTTCAATTGATTTGATTTAAGAAAAC
TCTTAGATTGCAAATCAAAC

Product: hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MRSRETYAVNKRLPIVVAAWLACCQSALADSLPPQAEHDGADARRLLQDSDRRFDNLIQQQRMRQLKSEGSNLEAERAPQ
MEGGSCLPVSGLKLAGIRLLSREEVTALGPPRGTCLDIAELNRFSRALTALYLERGFIAARVRPEGPDADGALTLRVVEG
KVAAIRGDADAPKAGNLFPGMLGKPLNVHDLDQGLDQANRLRSNKVTVDVLPGDAAGESALQLHNQPAVRLSGGLSLDNA
GRDSTGRMQAGASLNWDNPADWSDLLNLSVQTTTARQEIRHSRSESLFYSLPYGYWTLSAFASHADYLIPNTLQSGLVVQ
LSGTTEQNGLRLDRVLSRGQNHVLTADAQLVQKRVRNFFQDVRLDSSMNLTVLEAGVSQLLIQPAGLLQLDGSVQRGVRW
LGADAPDPLHPGAANPQFTKLRLGLAWFRGLALPGGPYQLQIALSGQASRDELPGVERLDIADASAVRGFRNNSLVSETG
WYWRNTLSRRFMAGGWSLTPRVGVDGGRVLQRDARETWQDIAGAAVGLALARGGLTLDLDYSRPLRKPQGWLSEGHILFA
RLNWQW

Sequences:

>Translated_566_residues
MRSRETYAVNKRLPIVVAAWLACCQSALADSLPPQAEHDGADARRLLQDSDRRFDNLIQQQRMRQLKSEGSNLEAERAPQ
MEGGSCLPVSGLKLAGIRLLSREEVTALGPPRGTCLDIAELNRFSRALTALYLERGFIAARVRPEGPDADGALTLRVVEG
KVAAIRGDADAPKAGNLFPGMLGKPLNVHDLDQGLDQANRLRSNKVTVDVLPGDAAGESALQLHNQPAVRLSGGLSLDNA
GRDSTGRMQAGASLNWDNPADWSDLLNLSVQTTTARQEIRHSRSESLFYSLPYGYWTLSAFASHADYLIPNTLQSGLVVQ
LSGTTEQNGLRLDRVLSRGQNHVLTADAQLVQKRVRNFFQDVRLDSSMNLTVLEAGVSQLLIQPAGLLQLDGSVQRGVRW
LGADAPDPLHPGAANPQFTKLRLGLAWFRGLALPGGPYQLQIALSGQASRDELPGVERLDIADASAVRGFRNNSLVSETG
WYWRNTLSRRFMAGGWSLTPRVGVDGGRVLQRDARETWQDIAGAAVGLALARGGLTLDLDYSRPLRKPQGWLSEGHILFA
RLNWQW
>Mature_566_residues
MRSRETYAVNKRLPIVVAAWLACCQSALADSLPPQAEHDGADARRLLQDSDRRFDNLIQQQRMRQLKSEGSNLEAERAPQ
MEGGSCLPVSGLKLAGIRLLSREEVTALGPPRGTCLDIAELNRFSRALTALYLERGFIAARVRPEGPDADGALTLRVVEG
KVAAIRGDADAPKAGNLFPGMLGKPLNVHDLDQGLDQANRLRSNKVTVDVLPGDAAGESALQLHNQPAVRLSGGLSLDNA
GRDSTGRMQAGASLNWDNPADWSDLLNLSVQTTTARQEIRHSRSESLFYSLPYGYWTLSAFASHADYLIPNTLQSGLVVQ
LSGTTEQNGLRLDRVLSRGQNHVLTADAQLVQKRVRNFFQDVRLDSSMNLTVLEAGVSQLLIQPAGLLQLDGSVQRGVRW
LGADAPDPLHPGAANPQFTKLRLGLAWFRGLALPGGPYQLQIALSGQASRDELPGVERLDIADASAVRGFRNNSLVSETG
WYWRNTLSRRFMAGGWSLTPRVGVDGGRVLQRDARETWQDIAGAAVGLALARGGLTLDLDYSRPLRKPQGWLSEGHILFA
RLNWQW

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 61754; Mature: 61754

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRETYAVNKRLPIVVAAWLACCQSALADSLPPQAEHDGADARRLLQDSDRRFDNLIQQ
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QRMRQLKSEGSNLEAERAPQMEGGSCLPVSGLKLAGIRLLSREEVTALGPPRGTCLDIAE
HHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCEECCEEEECCCCCEECCCCCCCEECHHH
LNRFSRALTALYLERGFIAARVRPEGPDADGALTLRVVEGKVAAIRGDADAPKAGNLFPG
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCH
MLGKPLNVHDLDQGLDQANRLRSNKVTVDVLPGDAAGESALQLHNQPAVRLSGGLSLDNA
HCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCCEEEECCCCCCCC
GRDSTGRMQAGASLNWDNPADWSDLLNLSVQTTTARQEIRHSRSESLFYSLPYGYWTLSA
CCCCCCCEECCCCCCCCCCCCHHHHHCCEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHH
FASHADYLIPNTLQSGLVVQLSGTTEQNGLRLDRVLSRGQNHVLTADAQLVQKRVRNFFQ
HHHCCCCCCCCHHCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHH
DVRLDSSMNLTVLEAGVSQLLIQPAGLLQLDGSVQRGVRWLGADAPDPLHPGAANPQFTK
HHCCCCCCCEEEEHHHHHHHHHCCCCCEEECCCHHHCHHHHCCCCCCCCCCCCCCCCHHH
LRLGLAWFRGLALPGGPYQLQIALSGQASRDELPGVERLDIADASAVRGFRNNSLVSETG
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCEECCCCHHHHCCCCCCCCCCCCC
WYWRNTLSRRFMAGGWSLTPRVGVDGGRVLQRDARETWQDIAGAAVGLALARGGLTLDLD
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
YSRPLRKPQGWLSEGHILFARLNWQW
CCCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MRSRETYAVNKRLPIVVAAWLACCQSALADSLPPQAEHDGADARRLLQDSDRRFDNLIQQ
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QRMRQLKSEGSNLEAERAPQMEGGSCLPVSGLKLAGIRLLSREEVTALGPPRGTCLDIAE
HHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCEECCEEEECCCCCEECCCCCCCEECHHH
LNRFSRALTALYLERGFIAARVRPEGPDADGALTLRVVEGKVAAIRGDADAPKAGNLFPG
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCH
MLGKPLNVHDLDQGLDQANRLRSNKVTVDVLPGDAAGESALQLHNQPAVRLSGGLSLDNA
HCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCCEEEECCCCCCCC
GRDSTGRMQAGASLNWDNPADWSDLLNLSVQTTTARQEIRHSRSESLFYSLPYGYWTLSA
CCCCCCCEECCCCCCCCCCCCHHHHHCCEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHH
FASHADYLIPNTLQSGLVVQLSGTTEQNGLRLDRVLSRGQNHVLTADAQLVQKRVRNFFQ
HHHCCCCCCCCHHCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHH
DVRLDSSMNLTVLEAGVSQLLIQPAGLLQLDGSVQRGVRWLGADAPDPLHPGAANPQFTK
HHCCCCCCCEEEEHHHHHHHHHCCCCCEEECCCHHHCHHHHCCCCCCCCCCCCCCCCHHH
LRLGLAWFRGLALPGGPYQLQIALSGQASRDELPGVERLDIADASAVRGFRNNSLVSETG
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCEECCCCHHHHCCCCCCCCCCCCC
WYWRNTLSRRFMAGGWSLTPRVGVDGGRVLQRDARETWQDIAGAAVGLALARGGLTLDLD
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
YSRPLRKPQGWLSEGHILFARLNWQW
CCCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]