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The map label for this gene is hipO [H]

Identifier: 34497339

GI number: 34497339

Start: 2045544

End: 2046758

Strand: Direct

Name: hipO [H]

Synonym: CV_1884

Alternate gene names: 34497339

Gene position: 2045544-2046758 (Clockwise)

Preceding gene: 161594052

Following gene: 34497340

Centisome position: 43.05

GC content: 67.82

Gene sequence:

>1215_bases
ATGCAGGCAGACAGGCAAGGCCGGCTGAGCGGTTTCGCGATGCTGTCCGACGCCGCCGTCCAGGAGATGGCGGCGTGGCG
GCAGGACTTGCACCGCCATCCGGAAACCGCGTTCGACGAGCATCGCACCGCCGGCAAGATCGCCGGGCTGTTGCGCAGCT
TCGGCCTGGAGGTGGCGACCGGCATAGGCCGCACCGGCGTGGTGGGCACGCTGCGCGCCGGCGGCGGCAGTCGTTCCATC
GGCCTGCGCGCCGACATGGACGCGCTGCATCTGCACGAGCAAGGCGAGCTGCCTTACCGTTCGCAGCACGCCGGCCGCAT
GCACGCCTGCGGCCACGACGGCCATTGCGCGATGCTGCTGGGCGCCGCCAGGCACCTGGCCGAGAGCCGCGCTTTCGACG
GCACCGTCCAGTTCATCTTTCAGCCGGCCGAGGAGAACGAGGGCGGCGGACAGGAGATGCTGGAAGACGGGCTGTTCGAG
CGTTTTCCGGTGGACGGCGTCTACGGCATGCACAACTGGCCCGGCCTGCCGCTGGGGCAGATGGCCATGAATCCGGGGCC
GATGATGATGGCTTTCGACCTGTTCGAGATCCGTCTGCGCGGCCAGGGCGGGCACGCCGCGATGCCGGAGCGCACCCGCG
ACGTGATCGCCGCCCAGGCGCAGCTGGTGACGGCGCTGCAGAGCATCGTCAGCCGCAATATCGACCCGCTGGACTGCGCG
GTGCTGTCCGTCACTCAGGTCGAGGCGGGTTCCACCTGGAACATCATTCCCGAGCAGGCGCTGCTGCGCGGCACCGTGCG
TTACGTCGATCCGGCGGTACAGGCTGTGATAGAGAGCCGGATGCGCGAATTGGTCGATCACATCGCGCTGGCGATGGGCG
TGGAGGCGGACATGGATTACTGGTACCGCTACCCGGCCACCATCAACGCCGAAGAGGAGACTTGGCTGGCGGCCGATGTC
GCCGCGCAATTGCTGGGCGAGGCCAATGTGCGCACCAAGATGCGTCCGTCGATGGCGTCCGAGGATTTCGCCTTCATGCT
GCGCGAGCGTCCCGGCTGCTATGCCTGGCTGGGCGTGGACGGACCCGCGCCTGGCGCCGGCCTGCACAGCCCGCATTACG
ATTTCAACGATCAGGCGCTGGCGATAGGCGCCGCGTACTGGATCAAACTGGTGGAAACCGCTTTGGCCCCGGCGGCCAAA
CCGACGGAACGATAA

Upstream 100 bases:

>100_bases
TTGTCATTTGCTTATAATCGCCGCTCATAATGACAAGGTACTTTCGCGGCATAGTGGTTCAAGCCATATGGTTTGACCGG
CCGCGGATCGGGAGAAGGGT

Downstream 100 bases:

>100_bases
CGGGAAGAAGAGCATGGCGCATGCGGGTGTTGGGCAATTGCAGGGCGGGGCGGCGGCGGGCGCGGGATTCAACCGCCTGG
CCCACCTGATGGCGATAGGC

Product: hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQADRQGRLSGFAMLSDAAVQEMAAWRQDLHRHPETAFDEHRTAGKIAGLLRSFGLEVATGIGRTGVVGTLRAGGGSRSI
GLRADMDALHLHEQGELPYRSQHAGRMHACGHDGHCAMLLGAARHLAESRAFDGTVQFIFQPAEENEGGGQEMLEDGLFE
RFPVDGVYGMHNWPGLPLGQMAMNPGPMMMAFDLFEIRLRGQGGHAAMPERTRDVIAAQAQLVTALQSIVSRNIDPLDCA
VLSVTQVEAGSTWNIIPEQALLRGTVRYVDPAVQAVIESRMRELVDHIALAMGVEADMDYWYRYPATINAEEETWLAADV
AAQLLGEANVRTKMRPSMASEDFAFMLRERPGCYAWLGVDGPAPGAGLHSPHYDFNDQALAIGAAYWIKLVETALAPAAK
PTER

Sequences:

>Translated_404_residues
MQADRQGRLSGFAMLSDAAVQEMAAWRQDLHRHPETAFDEHRTAGKIAGLLRSFGLEVATGIGRTGVVGTLRAGGGSRSI
GLRADMDALHLHEQGELPYRSQHAGRMHACGHDGHCAMLLGAARHLAESRAFDGTVQFIFQPAEENEGGGQEMLEDGLFE
RFPVDGVYGMHNWPGLPLGQMAMNPGPMMMAFDLFEIRLRGQGGHAAMPERTRDVIAAQAQLVTALQSIVSRNIDPLDCA
VLSVTQVEAGSTWNIIPEQALLRGTVRYVDPAVQAVIESRMRELVDHIALAMGVEADMDYWYRYPATINAEEETWLAADV
AAQLLGEANVRTKMRPSMASEDFAFMLRERPGCYAWLGVDGPAPGAGLHSPHYDFNDQALAIGAAYWIKLVETALAPAAK
PTER
>Mature_404_residues
MQADRQGRLSGFAMLSDAAVQEMAAWRQDLHRHPETAFDEHRTAGKIAGLLRSFGLEVATGIGRTGVVGTLRAGGGSRSI
GLRADMDALHLHEQGELPYRSQHAGRMHACGHDGHCAMLLGAARHLAESRAFDGTVQFIFQPAEENEGGGQEMLEDGLFE
RFPVDGVYGMHNWPGLPLGQMAMNPGPMMMAFDLFEIRLRGQGGHAAMPERTRDVIAAQAQLVTALQSIVSRNIDPLDCA
VLSVTQVEAGSTWNIIPEQALLRGTVRYVDPAVQAVIESRMRELVDHIALAMGVEADMDYWYRYPATINAEEETWLAADV
AAQLLGEANVRTKMRPSMASEDFAFMLRERPGCYAWLGVDGPAPGAGLHSPHYDFNDQALAIGAAYWIKLVETALAPAAK
PTER

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=414, Percent_Identity=28.2608695652174, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 44027; Mature: 44027

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQADRQGRLSGFAMLSDAAVQEMAAWRQDLHRHPETAFDEHRTAGKIAGLLRSFGLEVAT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHH
GIGRTGVVGTLRAGGGSRSIGLRADMDALHLHEQGELPYRSQHAGRMHACGHDGHCAMLL
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHH
GAARHLAESRAFDGTVQFIFQPAEENEGGGQEMLEDGLFERFPVDGVYGMHNWPGLPLGQ
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCHHH
MAMNPGPMMMAFDLFEIRLRGQGGHAAMPERTRDVIAAQAQLVTALQSIVSRNIDPLDCA
HHCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VLSVTQVEAGSTWNIIPEQALLRGTVRYVDPAVQAVIESRMRELVDHIALAMGVEADMDY
HEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WYRYPATINAEEETWLAADVAAQLLGEANVRTKMRPSMASEDFAFMLRERPGCYAWLGVD
HEECCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECC
GPAPGAGLHSPHYDFNDQALAIGAAYWIKLVETALAPAAKPTER
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQADRQGRLSGFAMLSDAAVQEMAAWRQDLHRHPETAFDEHRTAGKIAGLLRSFGLEVAT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHH
GIGRTGVVGTLRAGGGSRSIGLRADMDALHLHEQGELPYRSQHAGRMHACGHDGHCAMLL
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHH
GAARHLAESRAFDGTVQFIFQPAEENEGGGQEMLEDGLFERFPVDGVYGMHNWPGLPLGQ
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCCHHH
MAMNPGPMMMAFDLFEIRLRGQGGHAAMPERTRDVIAAQAQLVTALQSIVSRNIDPLDCA
HHCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VLSVTQVEAGSTWNIIPEQALLRGTVRYVDPAVQAVIESRMRELVDHIALAMGVEADMDY
HEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
WYRYPATINAEEETWLAADVAAQLLGEANVRTKMRPSMASEDFAFMLRERPGCYAWLGVD
HEECCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECC
GPAPGAGLHSPHYDFNDQALAIGAAYWIKLVETALAPAAKPTER
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]