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The map label for this gene is sohB [H]

Identifier: 34497270

GI number: 34497270

Start: 1972369

End: 1973307

Strand: Reverse

Name: sohB [H]

Synonym: CV_1815

Alternate gene names: 34497270

Gene position: 1973307-1972369 (Counterclockwise)

Preceding gene: 34497271

Following gene: 34497269

Centisome position: 41.53

GC content: 63.9

Gene sequence:

>939_bases
ATGAGCGACACCCAAAACTGGGAACGACAACTGCTGGAAAAGCTCGCCTCCGCCTCCCTGGTGGAACAGCGCCGCAGCCG
GCAATGGAAAATCTTCTTCCGGCTGGCCTGGCTGCTGGTCATAGGCTTGATCGCCGCCAGCGTCTTCATGCGCGGCGAGG
AAAAAAGCGGCGCCAGCCTGACCGGCGGCGGCCATACCGCGGTGATCGAGCTGGACGGCGCCATCAGCAGCGAAAACGAA
ACCGGCAAGAAAATGATCTCGGCGCTGGACCACGCCTTCCGCGACAAGGGCACCAAGGGCGTGATCATCGACGCCAACAG
CCCCGGCGGCAGCCCGGTGCTGTCCGGCATGGTCTACGATGAAATCCGGCGCCTGAAGAAGCTGCATGCCGACATTCCCG
TCTACGTGGTGGTCAGCGAAGTCTGCGCGTCCGGCTGCTATTACATCGCCGCCGCCGCCGACAAGATTTTCGTCGACAAG
GCCAGCATCGTCGGCTCCATCGGCGTGCTGTCGGACGGTTTCGGCTTCACCGGCGCGATGGAAAAACTGGGCATAGACCG
CCGCTTGAAGACCGCCGGCGAGAACAAGGCGATGGGCGACCCGTTCTCCCCGCCCAATCCCAAACACGACGCCATCCGCC
AGCAATTGCTGGACGACATCCACCATCAGTTCATCCAGGCGGTGGAGACCGGCCGCGGCCAGCGGCTGAAGAAGGACGCC
CAGACATTCAGCGGCATGGTCTGGCTGGGCGAAAAAGCGATTCCGCTGGGACTGGCCGACGGCTACGGCACCGTCGCCTC
GGTGGCCCGCGACGTGGTCAAGGCCCAGAAGACCGTGGACTTCACCCAGCAGGACGACTTCTCCAGCCGAGTGGCTCGCC
GCATCGGCGTGGAGTTCGCCGGCGGCGTGAAGTCGCTGTTCGACGCCAAACTGTTCTGA

Upstream 100 bases:

>100_bases
GCGCTCGATGTGTTCGAGGAAAACGGCCAAGTCTGGCTGAATGTCATGCCCGCCTGAATTTTGCTAGACTCACGGGATTA
TCCTGGAGCAGGCCCGAAAA

Downstream 100 bases:

>100_bases
CACGCGGAGGCGGACATGGCATCGCGACGCAGGAAGCAGGAAGAAGAGCACGAGAACCACGAGCGCTGGCTGGTTTCCTA
CGCCGACTTCATCACGCTGC

Product: serine protease

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSDTQNWERQLLEKLASASLVEQRRSRQWKIFFRLAWLLVIGLIAASVFMRGEEKSGASLTGGGHTAVIELDGAISSENE
TGKKMISALDHAFRDKGTKGVIIDANSPGGSPVLSGMVYDEIRRLKKLHADIPVYVVVSEVCASGCYYIAAAADKIFVDK
ASIVGSIGVLSDGFGFTGAMEKLGIDRRLKTAGENKAMGDPFSPPNPKHDAIRQQLLDDIHHQFIQAVETGRGQRLKKDA
QTFSGMVWLGEKAIPLGLADGYGTVASVARDVVKAQKTVDFTQQDDFSSRVARRIGVEFAGGVKSLFDAKLF

Sequences:

>Translated_312_residues
MSDTQNWERQLLEKLASASLVEQRRSRQWKIFFRLAWLLVIGLIAASVFMRGEEKSGASLTGGGHTAVIELDGAISSENE
TGKKMISALDHAFRDKGTKGVIIDANSPGGSPVLSGMVYDEIRRLKKLHADIPVYVVVSEVCASGCYYIAAAADKIFVDK
ASIVGSIGVLSDGFGFTGAMEKLGIDRRLKTAGENKAMGDPFSPPNPKHDAIRQQLLDDIHHQFIQAVETGRGQRLKKDA
QTFSGMVWLGEKAIPLGLADGYGTVASVARDVVKAQKTVDFTQQDDFSSRVARRIGVEFAGGVKSLFDAKLF
>Mature_311_residues
SDTQNWERQLLEKLASASLVEQRRSRQWKIFFRLAWLLVIGLIAASVFMRGEEKSGASLTGGGHTAVIELDGAISSENET
GKKMISALDHAFRDKGTKGVIIDANSPGGSPVLSGMVYDEIRRLKKLHADIPVYVVVSEVCASGCYYIAAAADKIFVDKA
SIVGSIGVLSDGFGFTGAMEKLGIDRRLKTAGENKAMGDPFSPPNPKHDAIRQQLLDDIHHQFIQAVETGRGQRLKKDAQ
TFSGMVWLGEKAIPLGLADGYGTVASVARDVVKAQKTVDFTQQDDFSSRVARRIGVEFAGGVKSLFDAKLF

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=214, Percent_Identity=28.0373831775701, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 33821; Mature: 33690

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTQNWERQLLEKLASASLVEQRRSRQWKIFFRLAWLLVIGLIAASVFMRGEEKSGASL
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
TGGGHTAVIELDGAISSENETGKKMISALDHAFRDKGTKGVIIDANSPGGSPVLSGMVYD
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
EIRRLKKLHADIPVYVVVSEVCASGCYYIAAAADKIFVDKASIVGSIGVLSDGFGFTGAM
HHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EKLGIDRRLKTAGENKAMGDPFSPPNPKHDAIRQQLLDDIHHQFIQAVETGRGQRLKKDA
HHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QTFSGMVWLGEKAIPLGLADGYGTVASVARDVVKAQKTVDFTQQDDFSSRVARRIGVEFA
HHHCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHC
GGVKSLFDAKLF
CHHHHHHHHCCC
>Mature Secondary Structure 
SDTQNWERQLLEKLASASLVEQRRSRQWKIFFRLAWLLVIGLIAASVFMRGEEKSGASL
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
TGGGHTAVIELDGAISSENETGKKMISALDHAFRDKGTKGVIIDANSPGGSPVLSGMVYD
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
EIRRLKKLHADIPVYVVVSEVCASGCYYIAAAADKIFVDKASIVGSIGVLSDGFGFTGAM
HHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EKLGIDRRLKTAGENKAMGDPFSPPNPKHDAIRQQLLDDIHHQFIQAVETGRGQRLKKDA
HHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QTFSGMVWLGEKAIPLGLADGYGTVASVARDVVKAQKTVDFTQQDDFSSRVARRIGVEFA
HHHCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHC
GGVKSLFDAKLF
CHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA