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The map label for this gene is fur [H]

Identifier: 34497252

GI number: 34497252

Start: 1952343

End: 1952774

Strand: Direct

Name: fur [H]

Synonym: CV_1797

Alternate gene names: 34497252

Gene position: 1952343-1952774 (Clockwise)

Preceding gene: 34497246

Following gene: 34497253

Centisome position: 41.09

GC content: 61.34

Gene sequence:

>432_bases
ATGAGCAAAGCCAGTCACCTCAAAGATATCGGCCTCAAAGCCACCGGACCGCGTCTGAAAATCCTCGACCTGTTCGAGCA
GGGCGACGCCGGCCATATGTCCGCCGAAGACGTTTACCGCAAGCTTCTGGCGGAAAACATCGACATCGGGCTCGCCACCA
TTTACCGCGTGCTGACCCAGTTCGAACAGGCCGGCATCCTGGTGCGCCACCATTTCGAGACCGGCAAGGCGGTGTACGAG
CTGAACCAGGGCGGCCACCATGATCACATGGTCTGCGTCAGCTGCGGCAAGGTGGTGGAGTTCTTCGATCCGGAAATCGA
GGCGCTGCAGGACCGCATCGCCGAACAGCACGGCTTTCGCATCGTCGAACACGCGCTGTACATGTACGGCGAGTGCCCGG
ATTGCCTGGGCAAGAGCGGCCGCCGCGGATGA

Upstream 100 bases:

>100_bases
CATGGTACTCCGATTGACTCAAACGTTTATGAGGCTGTAATTAGGCAAAGCCGTCAAAAGGCTTTATCATGATTCGAAAA
CCGAGACACTTTATATCACG

Downstream 100 bases:

>100_bases
TTCCCTGGCTCGGTCCCGAGCCTGTCTTCCCGCCGGTGTCGCAGGCCCTGAGTCATCCCAACGGCCTGCTGGCCGCCGGC
GGCGATCTGTCGTCCCGCCG

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MSKASHLKDIGLKATGPRLKILDLFEQGDAGHMSAEDVYRKLLAENIDIGLATIYRVLTQFEQAGILVRHHFETGKAVYE
LNQGGHHDHMVCVSCGKVVEFFDPEIEALQDRIAEQHGFRIVEHALYMYGECPDCLGKSGRRG

Sequences:

>Translated_143_residues
MSKASHLKDIGLKATGPRLKILDLFEQGDAGHMSAEDVYRKLLAENIDIGLATIYRVLTQFEQAGILVRHHFETGKAVYE
LNQGGHHDHMVCVSCGKVVEFFDPEIEALQDRIAEQHGFRIVEHALYMYGECPDCLGKSGRRG
>Mature_142_residues
SKASHLKDIGLKATGPRLKILDLFEQGDAGHMSAEDVYRKLLAENIDIGLATIYRVLTQFEQAGILVRHHFETGKAVYEL
NQGGHHDHMVCVSCGKVVEFFDPEIEALQDRIAEQHGFRIVEHALYMYGECPDCLGKSGRRG

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=131, Percent_Identity=55.7251908396947, Blast_Score=156, Evalue=6e-40,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16010; Mature: 15878

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKASHLKDIGLKATGPRLKILDLFEQGDAGHMSAEDVYRKLLAENIDIGLATIYRVLTQ
CCCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
FEQAGILVRHHFETGKAVYELNQGGHHDHMVCVSCGKVVEFFDPEIEALQDRIAEQHGFR
HHHCCCCEEEECCCCCEEEECCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHCHH
IVEHALYMYGECPDCLGKSGRRG
HHHHHHHHHCCCHHHHCCCCCCC
>Mature Secondary Structure 
SKASHLKDIGLKATGPRLKILDLFEQGDAGHMSAEDVYRKLLAENIDIGLATIYRVLTQ
CCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
FEQAGILVRHHFETGKAVYELNQGGHHDHMVCVSCGKVVEFFDPEIEALQDRIAEQHGFR
HHHCCCCEEEECCCCCEEEECCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHCHH
IVEHALYMYGECPDCLGKSGRRG
HHHHHHHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]