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The map label for this gene is dapB

Identifier: 34497250

GI number: 34497250

Start: 1951062

End: 1951865

Strand: Reverse

Name: dapB

Synonym: CV_1795

Alternate gene names: 34497250

Gene position: 1951865-1951062 (Counterclockwise)

Preceding gene: 34497251

Following gene: 34497249

Centisome position: 41.08

GC content: 69.4

Gene sequence:

>804_bases
ATGAGCCAGAACATCGTGATCGTCGGCGCGTCCGGCCGCATGGGCCGCGTGCTGATCGAAGCGGTGCTGGACGCTCCCGG
CGCCCGGCTGCACGCGGCGATAGACCGCGCGGATTCGGGCTTCGTCGGCCAGGATGCCGGCCTGTTCTGCGGCCGCAGCA
GCGGCGTCTTCATCAGCTCGGACTTCATCGCCGCGCTGGACGGCGCCGACGTGGTGATCGACTTCACCCGCCCCGAAGGC
ACGCTGGAGCACATGCTGGCCTGCGTAGAGCGCGGCGTGCGCATGGTGATCGGCACCACCGGCTTCGATGACGAAGGCAA
AGCCGCCATCCGCGCCGCGGCCGGCAAGATCGGCATCGTGTTCGCGTCCAACTTCAGCGTGGGCGTCAACCTCACCTTCA
AGCTGCTGGACATGGCCGCCCGCGTGCTGAACGAAGGCTACGACGTCGAAATCATCGAGGCGCACCACCGCTTCAAAGTG
GACGCGCCGTCCGGCACCGCGCTGCGCATGGGCGAAGTGATCGCCGACGCGCTGGGCCGCGATCTGAAGCAATGCGCGGT
CTATGGCCGCGAAGGCGTGACCGGCGAGCGCGACCCGCAGGCGATAGGCTTCGCGACCGTGCGCGGCGGCGACGTGGTCG
GCGACCACACCGCGCTGTTCGCCGCGCTGGGCGAGCGCGTGGAGATCAGCCACAAGGCTTCCAGCCGCGCCACGTTCGCC
AACGGCGCGGTGCGCGCCGCGCGCTGGCTGTCCGACAAGCGAAACGGCCTGTTCGACATGCAGGACGTGCTGGGCCTGCG
CTGA

Upstream 100 bases:

>100_bases
TCAAGGGCGACGCGCTGGACCGCGTCGAAGGCAATGCCCAACCGGCGCCGCCCGCCAAGCAGCTGGACGCTTCCGCCCCC
GCCCAGGAGGCGAAAAAGCC

Downstream 100 bases:

>100_bases
CGCCCGCGGAGGGGCGCCCGCCCCTCCCTTTCCATCCCATGCGCGTTCGCTCCCTCATCCTCGTCCTGCTTCCGCTGCTG
GGCCTCACCGCCCTCGCCTC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSQNIVIVGASGRMGRVLIEAVLDAPGARLHAAIDRADSGFVGQDAGLFCGRSSGVFISSDFIAALDGADVVIDFTRPEG
TLEHMLACVERGVRMVIGTTGFDDEGKAAIRAAAGKIGIVFASNFSVGVNLTFKLLDMAARVLNEGYDVEIIEAHHRFKV
DAPSGTALRMGEVIADALGRDLKQCAVYGREGVTGERDPQAIGFATVRGGDVVGDHTALFAALGERVEISHKASSRATFA
NGAVRAARWLSDKRNGLFDMQDVLGLR

Sequences:

>Translated_267_residues
MSQNIVIVGASGRMGRVLIEAVLDAPGARLHAAIDRADSGFVGQDAGLFCGRSSGVFISSDFIAALDGADVVIDFTRPEG
TLEHMLACVERGVRMVIGTTGFDDEGKAAIRAAAGKIGIVFASNFSVGVNLTFKLLDMAARVLNEGYDVEIIEAHHRFKV
DAPSGTALRMGEVIADALGRDLKQCAVYGREGVTGERDPQAIGFATVRGGDVVGDHTALFAALGERVEISHKASSRATFA
NGAVRAARWLSDKRNGLFDMQDVLGLR
>Mature_266_residues
SQNIVIVGASGRMGRVLIEAVLDAPGARLHAAIDRADSGFVGQDAGLFCGRSSGVFISSDFIAALDGADVVIDFTRPEGT
LEHMLACVERGVRMVIGTTGFDDEGKAAIRAAAGKIGIVFASNFSVGVNLTFKLLDMAARVLNEGYDVEIIEAHHRFKVD
APSGTALRMGEVIADALGRDLKQCAVYGREGVTGERDPQAIGFATVRGGDVVGDHTALFAALGERVEISHKASSRATFAN
GAVRAARWLSDKRNGLFDMQDVLGLR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=63.2575757575758, Blast_Score=304, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_CHRVO (Q7NX34)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901465.1
- ProteinModelPortal:   Q7NX34
- SMR:   Q7NX34
- GeneID:   2550432
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1795
- NMPDR:   fig|243365.1.peg.1795
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q7NX34
- ProtClustDB:   PRK00048
- BioCyc:   CVIO243365:CV_1795-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28178; Mature: 28047

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNIVIVGASGRMGRVLIEAVLDAPGARLHAAIDRADSGFVGQDAGLFCGRSSGVFISS
CCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEC
DFIAALDGADVVIDFTRPEGTLEHMLACVERGVRMVIGTTGFDDEGKAAIRAAAGKIGIV
CCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHEECCCEEEEE
FASNFSVGVNLTFKLLDMAARVLNEGYDVEIIEAHHRFKVDAPSGTALRMGEVIADALGR
EECCCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHH
DLKQCAVYGREGVTGERDPQAIGFATVRGGDVVGDHTALFAALGERVEISHKASSRATFA
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEECCCCCCCCHH
NGAVRAARWLSDKRNGLFDMQDVLGLR
CCHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure 
SQNIVIVGASGRMGRVLIEAVLDAPGARLHAAIDRADSGFVGQDAGLFCGRSSGVFISS
CCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEC
DFIAALDGADVVIDFTRPEGTLEHMLACVERGVRMVIGTTGFDDEGKAAIRAAAGKIGIV
CCEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHEECCCEEEEE
FASNFSVGVNLTFKLLDMAARVLNEGYDVEIIEAHHRFKVDAPSGTALRMGEVIADALGR
EECCCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHH
DLKQCAVYGREGVTGERDPQAIGFATVRGGDVVGDHTALFAALGERVEISHKASSRATFA
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEECCCCCCCCHH
NGAVRAARWLSDKRNGLFDMQDVLGLR
CCHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782