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The map label for this gene is prkA [H]

Identifier: 34497244

GI number: 34497244

Start: 1943747

End: 1945675

Strand: Direct

Name: prkA [H]

Synonym: CV_1789

Alternate gene names: 34497244

Gene position: 1943747-1945675 (Clockwise)

Preceding gene: 34497243

Following gene: 34497245

Centisome position: 40.91

GC content: 58.53

Gene sequence:

>1929_bases
ATGCACCCGGATATCTTCAGTCACTACGCAGTGCGATACGACAAGACCCGCGAGGAGGAGTACACGATCCAGGAGTACCT
GGAGCTGTGCAAGAAAGATCCGGGCGCCTACGCCACGGCGGCGGAGCGCATGCTGACCGCCATCGGCGAGCCGGAACTGG
TCGATACCCGTCACGATTCGCGGCTGTCCCGCATTTTCTCCAACAAAGTCATCAAGGTTTACCCGGCGTTCCGCGATTTC
TACGGCACCGAAGAGGTGATCGAGCAGGTAGTCGCCTATTTCCGCCACGCGGCCCAGGGCCTGGAGGAGAAGAAGCAGAT
CCTCTATCTGCTGGGACCGGTCGGCGGCGGCAAGTCGTCGATCGCCGAGAAACTGAAGGAACTGATGGAGCTGGTGCCCT
TCTATTGCCTGAAGGGCAGCCCGGTCAACGAGTCGCCGCTGTCCCTGTTCAATTACGATGAAGACGGCCCCATCCTCGAA
GAGCAATACGGCATTCCGCGCCGTTACCTGAAAGGCATCCCCAGCCCGTGGGCGGTCAAGCGCCTGCACGAGTTCAACGG
CGACATCGGCCAGTTCCGCGTGGTCAAGCGCTATCCGTCGGTGCTGCGCCAGGTGGCCGTGGCCAAGACCGAGCCGGGCG
ACGAGAACAACCAGGACATCAGCTCGCTGGTGGGCAAGGTGGACATCCGCAAGCTGGAAAAGTACGCGCAGGACGATCCG
GACGCCTACAGCTATTCCGGCGGCCTGTGCCTGGCGAACCAGGGCTTGCTCGAGTTCGTCGAAATGTTCAAGGCGCCGAT
CAAGGTGCTGCACCCCTTGCTGACGGCCACCCAGGAAGGCAACTTCAAGGGCACTGAAGGCTTCGGCGCGATACCCTTCG
AAGGCATCATCCTCGCGCACTCCAACGAGAGCGAGTGGAAGCAGTTCCGCAACAACAAGAACAACGAGGCCTTCCTCGAC
CGGATCTACATCGTCAAGGTGCCTTACTGCCTGCGCGTGGCCGAGGAAATCAAGATCTACGACAAGCTGATCCGCAACTC
CTCGCTGGGCAAGGCGCCGTGCGCGCCGGGCACGCTGAAGATGATGGCCCAGTTCGCGGTGCTGTCGCGGCTGAAGGAAC
CGGAAAACTCCAGCCTGTACAGCAAGATGCAGGTGTATGACGGCGAGAACCTGAAAGACACCGATCCCAAGGCCAAGTCG
CTGCAGGAATACCGCGACTACGCCGGCGTGGACGAAGGCATGTCGGGCTTGTCCACCCGTTTCGCCTACAAGATCCTGTC
CAAGGTGTTCAACTTCGACCACAGCGAAGTGGCCGCCAACCCGGTGCATTTGCTGTACGTGATCGAGCAGCAGGTCGAGC
GCGAACAGTTTCCAGCCGAAACGGAACAGAAATACCTGACTTTCCTGAAGGAATATCTGGCGCCGAAATACGTTGAATTC
ATCGGCAAGGAAATCCAGACCGCCTATCTGGAAAGTTATTCCGAATATGGCCAGAACATTTTCGACCGTTATGTGACTTT
CGCCGATTACTGGATTCAGGATCAGGAATATCGCGACCAAGATACCGGCGAAATATTCGACCGCACGTCGCTGAATGCGG
AACTGGAAAAGATCGAGAAGCCGGCGGGAATCTCCAATCCCAAGGATTTCCGCAACGAGATCGTCAACTTCGTGTTGCGG
GCCCGCGCCAACAACGGCGGCAAGAATCCGACCTGGACCAGTTACGAGAAGCTGCGCACGGTGATCGAGAAGAAGATGTT
CTCCAATACCGAGGAGCTGCTGCCGGTGATCTCCTTCAATGCCAAGGCCAGCGCCGAGGATGCCAAGAAGCACGAAGACT
TCGTCAACCGCATGGTGGAAAAGGGTTACACCGCCAAGCAGGTGCGGCTGCTGTGCGAATGGTATCTGCGCGTGCGCAAG
TCCTCATAA

Upstream 100 bases:

>100_bases
AACAGAACCGGAGACACCGTCAGTACTCTAATTCAGCAAGGGGAAAGGCAGATTGCGAGTCGCAGCATGCCAAGCCCCTG
CTACCAGCCAGGAGAGAGTC

Downstream 100 bases:

>100_bases
GCCGCCCGCGCCGGCTTGGCTCCCCGAGCCAGGCCGGCAGGAGGCGCCGACCCCAGATGGGGCGGCGACAAGGAGACACA
ACCGCGCGCGGCGATCGGCC

Product: protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MHPDIFSHYAVRYDKTREEEYTIQEYLELCKKDPGAYATAAERMLTAIGEPELVDTRHDSRLSRIFSNKVIKVYPAFRDF
YGTEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIAEKLKELMELVPFYCLKGSPVNESPLSLFNYDEDGPILE
EQYGIPRRYLKGIPSPWAVKRLHEFNGDIGQFRVVKRYPSVLRQVAVAKTEPGDENNQDISSLVGKVDIRKLEKYAQDDP
DAYSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFEGIILAHSNESEWKQFRNNKNNEAFLD
RIYIVKVPYCLRVAEEIKIYDKLIRNSSLGKAPCAPGTLKMMAQFAVLSRLKEPENSSLYSKMQVYDGENLKDTDPKAKS
LQEYRDYAGVDEGMSGLSTRFAYKILSKVFNFDHSEVAANPVHLLYVIEQQVEREQFPAETEQKYLTFLKEYLAPKYVEF
IGKEIQTAYLESYSEYGQNIFDRYVTFADYWIQDQEYRDQDTGEIFDRTSLNAELEKIEKPAGISNPKDFRNEIVNFVLR
ARANNGGKNPTWTSYEKLRTVIEKKMFSNTEELLPVISFNAKASAEDAKKHEDFVNRMVEKGYTAKQVRLLCEWYLRVRK
SS

Sequences:

>Translated_642_residues
MHPDIFSHYAVRYDKTREEEYTIQEYLELCKKDPGAYATAAERMLTAIGEPELVDTRHDSRLSRIFSNKVIKVYPAFRDF
YGTEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIAEKLKELMELVPFYCLKGSPVNESPLSLFNYDEDGPILE
EQYGIPRRYLKGIPSPWAVKRLHEFNGDIGQFRVVKRYPSVLRQVAVAKTEPGDENNQDISSLVGKVDIRKLEKYAQDDP
DAYSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFEGIILAHSNESEWKQFRNNKNNEAFLD
RIYIVKVPYCLRVAEEIKIYDKLIRNSSLGKAPCAPGTLKMMAQFAVLSRLKEPENSSLYSKMQVYDGENLKDTDPKAKS
LQEYRDYAGVDEGMSGLSTRFAYKILSKVFNFDHSEVAANPVHLLYVIEQQVEREQFPAETEQKYLTFLKEYLAPKYVEF
IGKEIQTAYLESYSEYGQNIFDRYVTFADYWIQDQEYRDQDTGEIFDRTSLNAELEKIEKPAGISNPKDFRNEIVNFVLR
ARANNGGKNPTWTSYEKLRTVIEKKMFSNTEELLPVISFNAKASAEDAKKHEDFVNRMVEKGYTAKQVRLLCEWYLRVRK
SS
>Mature_642_residues
MHPDIFSHYAVRYDKTREEEYTIQEYLELCKKDPGAYATAAERMLTAIGEPELVDTRHDSRLSRIFSNKVIKVYPAFRDF
YGTEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIAEKLKELMELVPFYCLKGSPVNESPLSLFNYDEDGPILE
EQYGIPRRYLKGIPSPWAVKRLHEFNGDIGQFRVVKRYPSVLRQVAVAKTEPGDENNQDISSLVGKVDIRKLEKYAQDDP
DAYSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFEGIILAHSNESEWKQFRNNKNNEAFLD
RIYIVKVPYCLRVAEEIKIYDKLIRNSSLGKAPCAPGTLKMMAQFAVLSRLKEPENSSLYSKMQVYDGENLKDTDPKAKS
LQEYRDYAGVDEGMSGLSTRFAYKILSKVFNFDHSEVAANPVHLLYVIEQQVEREQFPAETEQKYLTFLKEYLAPKYVEF
IGKEIQTAYLESYSEYGQNIFDRYVTFADYWIQDQEYRDQDTGEIFDRTSLNAELEKIEKPAGISNPKDFRNEIVNFVLR
ARANNGGKNPTWTSYEKLRTVIEKKMFSNTEELLPVISFNAKASAEDAKKHEDFVNRMVEKGYTAKQVRLLCEWYLRVRK
SS

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=643, Percent_Identity=77.293934681182, Blast_Score=1060, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 73769; Mature: 73769

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPDIFSHYAVRYDKTREEEYTIQEYLELCKKDPGAYATAAERMLTAIGEPELVDTRHDS
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHH
RLSRIFSNKVIKVYPAFRDFYGTEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSS
HHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHH
IAEKLKELMELVPFYCLKGSPVNESPLSLFNYDEDGPILEEQYGIPRRYLKGIPSPWAVK
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHCCCCHHHHCCCCCHHHHH
RLHEFNGDIGQFRVVKRYPSVLRQVAVAKTEPGDENNQDISSLVGKVDIRKLEKYAQDDP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DAYSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFEGIILAH
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
SNESEWKQFRNNKNNEAFLDRIYIVKVPYCLRVAEEIKIYDKLIRNSSLGKAPCAPGTLK
CCHHHHHHHHCCCCCHHHHHHHHEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
MMAQFAVLSRLKEPENSSLYSKMQVYDGENLKDTDPKAKSLQEYRDYAGVDEGMSGLSTR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
FAYKILSKVFNFDHSEVAANPVHLLYVIEQQVEREQFPAETEQKYLTFLKEYLAPKYVEF
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHH
IGKEIQTAYLESYSEYGQNIFDRYVTFADYWIQDQEYRDQDTGEIFDRTSLNAELEKIEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCHHHHHHCC
PAGISNPKDFRNEIVNFVLRARANNGGKNPTWTSYEKLRTVIEKKMFSNTEELLPVISFN
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCC
AKASAEDAKKHEDFVNRMVEKGYTAKQVRLLCEWYLRVRKSS
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHPDIFSHYAVRYDKTREEEYTIQEYLELCKKDPGAYATAAERMLTAIGEPELVDTRHDS
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHH
RLSRIFSNKVIKVYPAFRDFYGTEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSS
HHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHH
IAEKLKELMELVPFYCLKGSPVNESPLSLFNYDEDGPILEEQYGIPRRYLKGIPSPWAVK
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCHHHHCCCCHHHHCCCCCHHHHH
RLHEFNGDIGQFRVVKRYPSVLRQVAVAKTEPGDENNQDISSLVGKVDIRKLEKYAQDDP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DAYSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFEGIILAH
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
SNESEWKQFRNNKNNEAFLDRIYIVKVPYCLRVAEEIKIYDKLIRNSSLGKAPCAPGTLK
CCHHHHHHHHCCCCCHHHHHHHHEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
MMAQFAVLSRLKEPENSSLYSKMQVYDGENLKDTDPKAKSLQEYRDYAGVDEGMSGLSTR
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
FAYKILSKVFNFDHSEVAANPVHLLYVIEQQVEREQFPAETEQKYLTFLKEYLAPKYVEF
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHH
IGKEIQTAYLESYSEYGQNIFDRYVTFADYWIQDQEYRDQDTGEIFDRTSLNAELEKIEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCHHHHHHCC
PAGISNPKDFRNEIVNFVLRARANNGGKNPTWTSYEKLRTVIEKKMFSNTEELLPVISFN
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCC
AKASAEDAKKHEDFVNRMVEKGYTAKQVRLLCEWYLRVRKSS
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]