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The map label for this gene is hemG [H]

Identifier: 34497108

GI number: 34497108

Start: 1791071

End: 1792405

Strand: Direct

Name: hemG [H]

Synonym: CV_1653

Alternate gene names: 34497108

Gene position: 1791071-1792405 (Clockwise)

Preceding gene: 34497106

Following gene: 34497109

Centisome position: 37.7

GC content: 71.01

Gene sequence:

>1335_bases
ATGGAATCGATTTTTCGGGAGACGATCATGATCGCGGTAATCGGCGCCGGCGTTTCAGGGCTGTCCTGCGCCTGGTGGCT
GCAACGGCACGGCATGCCGGTGCGGGTGTTCGAAGCGGCGGAACGCGTCGGCGGCAAGGTGAGCACCTTGGCGGGGGAGG
CGCTGTGCGAGCAGGGGCCCAATACGCTGCTGCTGGACGAGGAACTGGGGCAATGGCTGGCGGAGCTCGGCTTGTCGCCG
CTGTGGCCTGAGCAAGGGAGCGATTTGCGGCATGTGCTGCAGCGTGGGCGCTACCGGCCGTTGCCTGCCGGCCCCTGGCA
ACTGATGGCGGGCGGCCTGCTTAGCTGGCGGGCCAAATGGCAGCTGTTGCGCGGACTGTTGCGGCCGGGCGATCCGGCCG
AGGCCGAGTCCTCCCTTGCGGCTTTCTGCCGCCGCCGTTTCGGGCAGGAAGTGCTGGACAAGCTGCTGGACCCGCTGGCC
TGCGGCGTGTTCGCCGGGGATCCGGAGGAACTGGCGCTGGACGAGACGCTGCCCAGGCTGGCGCGGGCGGCGGCGCGGCC
GCTGCCATTGTGGAAGGGACTGTGGCGCGAAAGGGCCGGGCGCGCCCGGATGTGCACCTTGCCAGGCGGGCTGCAGCAAT
TGCCGCAGCGGCTGGCGCGGGATCTGGACATCAAGCTGGGCGCGCCGGTGACCGCGCTGCGCCGCGACGGCGACGGCTGG
CGGCTGCGTACCCGCGAGGGTTGGGAGTGGGCCGATCGGGTGGTGTTGGCCGTGCCGGCCGCCGCCGCCGCCGAGCTGCT
GCATCCGCTGGCGCCGGAAATGGCCGACGTCTGCCGGCGCATTCCGTACGCGCCGCTGGCCGTGGTGTCCACGCTGCTGG
ACGGGGAGGCGATGGAGAAGCCGCTGCCAGGCTACGGCGCGCTGCATCCGAGCGGGGAGGGCGCGTTGACGTTGGGCCAT
CTGACGGTCAGCAACATCTATCCGCACGTTTGTCCCGACGGCACCCGGCTGGTGACCAGCTTCATCGGCGGCCGCAAGCA
TCCGGAATGGCTGGAACAGGACGACGACGCGCTGCTGGCGGGGCTCAACCAGGAGCTGGAACGCCTGTTCGGCATGCGCG
GCAGGCCGCTGGCGCAGCACCTGACGCGTTGGCCGCAGGCCTTGCCGCAGGGCACGCCGCTGCAGCGCCGGCTGCGCGGC
GCGGCCGAGCAGTGGGGCGGACGGGGCTTGCATCTGTGCGTCAACTGGCTGGATGGCGCATCCCTGCCGGATTGCCTGAG
AAAAGGGCGGCGGCTGGCCCGGCGATTGGCGGAGCGGGAAGGCGGCTTTGCGTGA

Upstream 100 bases:

>100_bases
TATCGGTATAGCTCTTCGGGCGCGGGTCTTCGCCCCGCGGTGATGCCGGGCGCGGTTGACCGCAGTCAATGAGGGGTGGC
CATGGGCAAGGATAATCGTG

Downstream 100 bases:

>100_bases
GCGGCGTCAGGCGGTAGAATCGACCCTTGTTTCTTCAATTTTCCAACACCACCTTTATGCTTACCTTCCAGGAAATCATC
CTCACGCTCCAGCACTACTG

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MESIFRETIMIAVIGAGVSGLSCAWWLQRHGMPVRVFEAAERVGGKVSTLAGEALCEQGPNTLLLDEELGQWLAELGLSP
LWPEQGSDLRHVLQRGRYRPLPAGPWQLMAGGLLSWRAKWQLLRGLLRPGDPAEAESSLAAFCRRRFGQEVLDKLLDPLA
CGVFAGDPEELALDETLPRLARAAARPLPLWKGLWRERAGRARMCTLPGGLQQLPQRLARDLDIKLGAPVTALRRDGDGW
RLRTREGWEWADRVVLAVPAAAAAELLHPLAPEMADVCRRIPYAPLAVVSTLLDGEAMEKPLPGYGALHPSGEGALTLGH
LTVSNIYPHVCPDGTRLVTSFIGGRKHPEWLEQDDDALLAGLNQELERLFGMRGRPLAQHLTRWPQALPQGTPLQRRLRG
AAEQWGGRGLHLCVNWLDGASLPDCLRKGRRLARRLAEREGGFA

Sequences:

>Translated_444_residues
MESIFRETIMIAVIGAGVSGLSCAWWLQRHGMPVRVFEAAERVGGKVSTLAGEALCEQGPNTLLLDEELGQWLAELGLSP
LWPEQGSDLRHVLQRGRYRPLPAGPWQLMAGGLLSWRAKWQLLRGLLRPGDPAEAESSLAAFCRRRFGQEVLDKLLDPLA
CGVFAGDPEELALDETLPRLARAAARPLPLWKGLWRERAGRARMCTLPGGLQQLPQRLARDLDIKLGAPVTALRRDGDGW
RLRTREGWEWADRVVLAVPAAAAAELLHPLAPEMADVCRRIPYAPLAVVSTLLDGEAMEKPLPGYGALHPSGEGALTLGH
LTVSNIYPHVCPDGTRLVTSFIGGRKHPEWLEQDDDALLAGLNQELERLFGMRGRPLAQHLTRWPQALPQGTPLQRRLRG
AAEQWGGRGLHLCVNWLDGASLPDCLRKGRRLARRLAEREGGFA
>Mature_444_residues
MESIFRETIMIAVIGAGVSGLSCAWWLQRHGMPVRVFEAAERVGGKVSTLAGEALCEQGPNTLLLDEELGQWLAELGLSP
LWPEQGSDLRHVLQRGRYRPLPAGPWQLMAGGLLSWRAKWQLLRGLLRPGDPAEAESSLAAFCRRRFGQEVLDKLLDPLA
CGVFAGDPEELALDETLPRLARAAARPLPLWKGLWRERAGRARMCTLPGGLQQLPQRLARDLDIKLGAPVTALRRDGDGW
RLRTREGWEWADRVVLAVPAAAAAELLHPLAPEMADVCRRIPYAPLAVVSTLLDGEAMEKPLPGYGALHPSGEGALTLGH
LTVSNIYPHVCPDGTRLVTSFIGGRKHPEWLEQDDDALLAGLNQELERLFGMRGRPLAQHLTRWPQALPQGTPLQRRLRG
AAEQWGGRGLHLCVNWLDGASLPDCLRKGRRLARRLAEREGGFA

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. May have an essential extracellular function during development, possibly as a pheromone [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

Organism=Homo sapiens, GI170650615, Length=485, Percent_Identity=29.2783505154639, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4506001, Length=485, Percent_Identity=29.2783505154639, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR016040
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 48882; Mature: 48882

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIFRETIMIAVIGAGVSGLSCAWWLQRHGMPVRVFEAAERVGGKVSTLAGEALCEQGP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC
NTLLLDEELGQWLAELGLSPLWPEQGSDLRHVLQRGRYRPLPAGPWQLMAGGLLSWRAKW
CEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QLLRGLLRPGDPAEAESSLAAFCRRRFGQEVLDKLLDPLACGVFAGDPEELALDETLPRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ARAAARPLPLWKGLWRERAGRARMCTLPGGLQQLPQRLARDLDIKLGAPVTALRRDGDGW
HHHHCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCC
RLRTREGWEWADRVVLAVPAAAAAELLHPLAPEMADVCRRIPYAPLAVVSTLLDGEAMEK
EEECCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHC
PLPGYGALHPSGEGALTLGHLTVSNIYPHVCPDGTRLVTSFIGGRKHPEWLEQDDDALLA
CCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHH
GLNQELERLFGMRGRPLAQHLTRWPQALPQGTPLQRRLRGAAEQWGGRGLHLCVNWLDGA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCC
SLPDCLRKGRRLARRLAEREGGFA
CCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MESIFRETIMIAVIGAGVSGLSCAWWLQRHGMPVRVFEAAERVGGKVSTLAGEALCEQGP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC
NTLLLDEELGQWLAELGLSPLWPEQGSDLRHVLQRGRYRPLPAGPWQLMAGGLLSWRAKW
CEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QLLRGLLRPGDPAEAESSLAAFCRRRFGQEVLDKLLDPLACGVFAGDPEELALDETLPRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ARAAARPLPLWKGLWRERAGRARMCTLPGGLQQLPQRLARDLDIKLGAPVTALRRDGDGW
HHHHCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCC
RLRTREGWEWADRVVLAVPAAAAAELLHPLAPEMADVCRRIPYAPLAVVSTLLDGEAMEK
EEECCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHC
PLPGYGALHPSGEGALTLGHLTVSNIYPHVCPDGTRLVTSFIGGRKHPEWLEQDDDALLA
CCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHH
GLNQELERLFGMRGRPLAQHLTRWPQALPQGTPLQRRLRGAAEQWGGRGLHLCVNWLDGA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCC
SLPDCLRKGRRLARRLAEREGGFA
CCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1372277; 8621504 [H]