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The map label for this gene is dgk [H]

Identifier: 34497089

GI number: 34497089

Start: 1772110

End: 1772745

Strand: Direct

Name: dgk [H]

Synonym: CV_1634

Alternate gene names: 34497089

Gene position: 1772110-1772745 (Clockwise)

Preceding gene: 34497088

Following gene: 34497090

Centisome position: 37.3

GC content: 63.36

Gene sequence:

>636_bases
ATGAGTCAATTGCGATACGTGGTGGTGGAGGGGCCGATAGGCTCGGGCAAGTCTTCGCTGGCGCGCCGGCTGTCCGAATA
CTGGGGCGTGCAGCTGAAGGCCGAGGACCCGGCCGCCAATCCCTTCCTGCCGCGCTTCTATCGCAATATGCCGGCGCACG
CGCTGTCCACCCAGCTGAGCTTCCTGCTGCAGCGCGCCGACATCGCGCGCGAGATGATCAGCGGCGAATTGCAGGCCGCG
CCGCTGGTATCCGACTTCCTGTTTGAGAAGGACGCGCTGTTCGCCCGCCTCAACCTGGACGAGCACGAGCTGGCGATCTA
CCAGCGCCTGGCGAGGCTGGCGTTGCCGGAATACCCGGTGCCGGACCTGGTGATCTATCTGCAGGCGTCCGAGGACATCC
TGCTGCAGCGGGTGGCCGCGCGCGCCGTCGATTACGAGGTCAACTTCCCCGAGGGCTACCTCAAACGCGTGCATGCCGGC
TACAGCGAGTTTTTCCACCAGTACGAGGCGGCGCCGTTGCTGATCGTCAACACCGACCACTTGAATCTGGTGGACGGCGA
CGAGGACTTCGAGTTATTGATCCGCTGCATTGCCGAAATGCGCGGCCAGCGCAGTTATTTCAACAAGAGCGTCTGA

Upstream 100 bases:

>100_bases
TGCCGGGCGTCGGCGACATCGCCGCGCTGGCGGCGGACCTGGCCGGTTCCGGCGTGGCGCGCCTGGACGACGAGTCCAAC
CCCAACAAACAGGAACAAGC

Downstream 100 bases:

>100_bases
CCGGGTTGGTTCCCGCGCGGCGCCGAAGATGGAACGCGAGGAAGTCGAGATGAAAATAACCGTCAATACCCTGCACAAGC
TGGCCGAGGAAGGCCGGAAG

Product: deoxyguanosine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSQLRYVVVEGPIGSGKSSLARRLSEYWGVQLKAEDPAANPFLPRFYRNMPAHALSTQLSFLLQRADIAREMISGELQAA
PLVSDFLFEKDALFARLNLDEHELAIYQRLARLALPEYPVPDLVIYLQASEDILLQRVAARAVDYEVNFPEGYLKRVHAG
YSEFFHQYEAAPLLIVNTDHLNLVDGDEDFELLIRCIAEMRGQRSYFNKSV

Sequences:

>Translated_211_residues
MSQLRYVVVEGPIGSGKSSLARRLSEYWGVQLKAEDPAANPFLPRFYRNMPAHALSTQLSFLLQRADIAREMISGELQAA
PLVSDFLFEKDALFARLNLDEHELAIYQRLARLALPEYPVPDLVIYLQASEDILLQRVAARAVDYEVNFPEGYLKRVHAG
YSEFFHQYEAAPLLIVNTDHLNLVDGDEDFELLIRCIAEMRGQRSYFNKSV
>Mature_210_residues
SQLRYVVVEGPIGSGKSSLARRLSEYWGVQLKAEDPAANPFLPRFYRNMPAHALSTQLSFLLQRADIAREMISGELQAAP
LVSDFLFEKDALFARLNLDEHELAIYQRLARLALPEYPVPDLVIYLQASEDILLQRVAARAVDYEVNFPEGYLKRVHAGY
SEFFHQYEAAPLLIVNTDHLNLVDGDEDFELLIRCIAEMRGQRSYFNKSV

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24080; Mature: 23949

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLRYVVVEGPIGSGKSSLARRLSEYWGVQLKAEDPAANPFLPRFYRNMPAHALSTQLS
CCCEEEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHCCCHHHHHHHHH
FLLQRADIAREMISGELQAAPLVSDFLFEKDALFARLNLDEHELAIYQRLARLALPEYPV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCCC
PDLVIYLQASEDILLQRVAARAVDYEVNFPEGYLKRVHAGYSEFFHQYEAAPLLIVNTDH
CCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCEEEEECCC
LNLVDGDEDFELLIRCIAEMRGQRSYFNKSV
EEEECCCCHHHHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
SQLRYVVVEGPIGSGKSSLARRLSEYWGVQLKAEDPAANPFLPRFYRNMPAHALSTQLS
CCEEEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHCCCHHHHHHHHH
FLLQRADIAREMISGELQAAPLVSDFLFEKDALFARLNLDEHELAIYQRLARLALPEYPV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCCC
PDLVIYLQASEDILLQRVAARAVDYEVNFPEGYLKRVHAGYSEFFHQYEAAPLLIVNTDH
CCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCCCEEEEECCC
LNLVDGDEDFELLIRCIAEMRGQRSYFNKSV
EEEECCCCHHHHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]