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The map label for this gene is fdhD

Identifier: 34497079

GI number: 34497079

Start: 1759698

End: 1760510

Strand: Direct

Name: fdhD

Synonym: CV_1624

Alternate gene names: 34497079

Gene position: 1759698-1760510 (Clockwise)

Preceding gene: 34497078

Following gene: 34497086

Centisome position: 37.04

GC content: 69.99

Gene sequence:

>813_bases
ATGAGCATGCAGGATCACGACAGAACGGAACAGGGAATGACATCGCTGGCGGTGACGCGCCATCTCGATGGGTCGAGCCG
GCCCGATTGGGACCGGGTGGCGGAGGAGACACCGGTGGCGCTGGTGTTCAACGGCATCTCGCACGCGGTGATGATGGCCA
CGCCGCTGGATCTTGAATGGCTGGCGGTGGGCTTCGCGCTGAGCGAAGGCATTGTCGCGCGGCGTGCGGAGATTTTCGAC
ATCGAGTCCGATTTCGTCTGCGGCGGCGCCGAGGTCAGGCTGGAAATCGCGCAGCCGGCCTTCCTGGCGCTGAAGGACAG
GCGACGCAGCCTGGCGGGCCGCACCGGATGCGGCGTGTGCGGCATCGAGAGCCTGGCGATGCTGGATCTGTCCCCCGAGC
CCATCGCCGGGCCGGCGGGGCCCGTGTCCGCCGATCCGGCCGCGATCGCGCGCGCGGCGGCCGAGCTGCCGGCCCATCAG
CGGCTGATGCAGGCGACGGGCTGCGCGCACGCGGCGGCCTGGTGCGGCCGCGACGGCGGGGTGAGGATGGCGTTCGAGGA
TGTGGGCCGGCACAATGCGCTGGACAAGCTGATAGGCTGGCTGGCGCTCGAGGGCATGGACCCCGCGGACGGTTTCGTGT
TCATGTCCAGCCGCGCCAGCTACGAGTTGGCGCGCAAGTGCGCCAGAACCGGCATCCCGCTGTTGGCGACCATTTCCGCG
CCCACCTCGCTGGCGGTCGACATCGCGCGCCGCGCCGGCGTCGCGCTGGCCAGCTTCTGCAGGCGTACCGGCTTCGTCGA
GTACACGGCCTAG

Upstream 100 bases:

>100_bases
CGGGGACAGGGCGCGCCAGTATAAGCGATGGCGGCGAGCCGGGCGGACGGATCGGTGGATTTTTTTGCAGCGGGCGCCGC
GGGCGGCCGCGGATGGGCGG

Downstream 100 bases:

>100_bases
GGCGCCGGCTCATCTCCGGGAGGCGGCGGCCAGATCGTCCGGTGTGTTGAGATTGCGAAAGGCCTGCGGCGCGTCGTCGA
AGTCCACCATCGCCGCTCCC

Product: formate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSMQDHDRTEQGMTSLAVTRHLDGSSRPDWDRVAEETPVALVFNGISHAVMMATPLDLEWLAVGFALSEGIVARRAEIFD
IESDFVCGGAEVRLEIAQPAFLALKDRRRSLAGRTGCGVCGIESLAMLDLSPEPIAGPAGPVSADPAAIARAAAELPAHQ
RLMQATGCAHAAAWCGRDGGVRMAFEDVGRHNALDKLIGWLALEGMDPADGFVFMSSRASYELARKCARTGIPLLATISA
PTSLAVDIARRAGVALASFCRRTGFVEYTA

Sequences:

>Translated_270_residues
MSMQDHDRTEQGMTSLAVTRHLDGSSRPDWDRVAEETPVALVFNGISHAVMMATPLDLEWLAVGFALSEGIVARRAEIFD
IESDFVCGGAEVRLEIAQPAFLALKDRRRSLAGRTGCGVCGIESLAMLDLSPEPIAGPAGPVSADPAAIARAAAELPAHQ
RLMQATGCAHAAAWCGRDGGVRMAFEDVGRHNALDKLIGWLALEGMDPADGFVFMSSRASYELARKCARTGIPLLATISA
PTSLAVDIARRAGVALASFCRRTGFVEYTA
>Mature_269_residues
SMQDHDRTEQGMTSLAVTRHLDGSSRPDWDRVAEETPVALVFNGISHAVMMATPLDLEWLAVGFALSEGIVARRAEIFDI
ESDFVCGGAEVRLEIAQPAFLALKDRRRSLAGRTGCGVCGIESLAMLDLSPEPIAGPAGPVSADPAAIARAAAELPAHQR
LMQATGCAHAAAWCGRDGGVRMAFEDVGRHNALDKLIGWLALEGMDPADGFVFMSSRASYELARKCARTGIPLLATISAP
TSLAVDIARRAGVALASFCRRTGFVEYTA

Specific function: Necessary for formate dehydrogenase activity

COG id: COG1526

COG function: function code C; Uncharacterized protein required for formate dehydrogenase activity

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhD family

Homologues:

Organism=Escherichia coli, GI1790329, Length=269, Percent_Identity=44.2379182156134, Blast_Score=209, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FDHD_CHRVO (Q7NXK2)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901294.1
- ProteinModelPortal:   Q7NXK2
- SMR:   Q7NXK2
- GeneID:   2550612
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1624
- NMPDR:   fig|243365.1.peg.1624
- HOGENOM:   HBG732883
- OMA:   CHVTRHR
- PhylomeDB:   Q7NXK2
- ProtClustDB:   CLSK922548
- BioCyc:   CVIO243365:CV_1624-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00187
- InterPro:   IPR003786
- TIGRFAMs:   TIGR00129

Pfam domain/function: PF02634 FdhD-NarQ

EC number: NA

Molecular weight: Translated: 28682; Mature: 28551

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMQDHDRTEQGMTSLAVTRHLDGSSRPDWDRVAEETPVALVFNGISHAVMMATPLDLEW
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECCHHCEEEEECCCCHHH
LAVGFALSEGIVARRAEIFDIESDFVCGGAEVRLEIAQPAFLALKDRRRSLAGRTGCGVC
HHHHHHHHCCHHHHHHHEEECCCCEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCCHH
GIESLAMLDLSPEPIAGPAGPVSADPAAIARAAAELPAHQRLMQATGCAHAAAWCGRDGG
CCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHCCCCC
VRMAFEDVGRHNALDKLIGWLALEGMDPADGFVFMSSRASYELARKCARTGIPLLATISA
EEEHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECC
PTSLAVDIARRAGVALASFCRRTGFVEYTA
CHHHHHHHHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure 
SMQDHDRTEQGMTSLAVTRHLDGSSRPDWDRVAEETPVALVFNGISHAVMMATPLDLEW
CCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECCHHCEEEEECCCCHHH
LAVGFALSEGIVARRAEIFDIESDFVCGGAEVRLEIAQPAFLALKDRRRSLAGRTGCGVC
HHHHHHHHCCHHHHHHHEEECCCCEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCCHH
GIESLAMLDLSPEPIAGPAGPVSADPAAIARAAAELPAHQRLMQATGCAHAAAWCGRDGG
CCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHCCCCC
VRMAFEDVGRHNALDKLIGWLALEGMDPADGFVFMSSRASYELARKCARTGIPLLATISA
EEEHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECC
PTSLAVDIARRAGVALASFCRRTGFVEYTA
CHHHHHHHHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782