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The map label for this gene is ttdR [H]

Identifier: 34497086

GI number: 34497086

Start: 1769187

End: 1770101

Strand: Direct

Name: ttdR [H]

Synonym: CV_1631

Alternate gene names: 34497086

Gene position: 1769187-1770101 (Clockwise)

Preceding gene: 34497079

Following gene: 34497087

Centisome position: 37.24

GC content: 71.04

Gene sequence:

>915_bases
TTGATAAAAATGGTTAGAGTCGATGATTTGCAGGTATTCATCCGCGCCGCGGACAACGGCAGCCTGTCGGCCGCCGCGCG
CCAGCTGGACCTGAGCCCGGCGGTGGCCAGCGCCGCGTTGAAGCGGCTGGAGCAGGCGCTCGGCGCGCAGCTGCTGGCGC
GCTCGACCCGCAGCCTGAGGCTGACGCTGGCCGGCGAGCGCTACCTGGAGCACGCGCGCGCGGCGCTGGATGCGCTGCAG
GCCGGCAGCCTGGCGCTGGAGCAGGACAGGCGCGAGCTGTCGGGCAGCCTGTCGCTGTCGATGCCGTCGGACCTGGGGCG
CAACCTGCTGCGGCCATGGCTGGATGATTTTCTGCGCCGGCATCCCGGCCTGAGCCTGCAGTTGCAGATCAGCGACCGCG
TCGCCGATCTCTACCGCCAGCCGGTGGACGTGGCGTTGCGTTACGGCGTGCCGGAGGATTCCAGCCTGGTGGCGCTGCCG
CTGGCGGCTGACAACCGCCGGGTGCTGTGCGCGTCGCCGGACTACCTGGTCCGCCACGGCGCGCCGGAGACGCCGCAGGC
CCTGCGGGGCCGCCAGTGCCTGCGGCTGGTACTGGGCGCGGCGGTGCACGAGCGCTGGAGTTTCGAACGCCAGGGCGAGC
GGCAGACGGTGACGGTGTCCGGGCGCTGGCTCAGCGACGATGGAGAGATCGTGCGGCGCTGGGCGGTGGACGGCTGCGGC
ATCGCCTACAAGTCGCGGCTGGACGTGCTGGCCGATCTGCGCGCGGGCAGGCTGACGCCCCTGCTGCCCGATTACGGAAC
CGAGCCGACGCCGCTATGCCTGGTCACGCCGCATCGGCTGATGTTGTCGCCGGCGGTGGCCGCGTTGCGCGCGCATCTGC
AAGATTGCCTAGAACGGTATCTGGCGGAGCCGTGA

Upstream 100 bases:

>100_bases
GCAATCCCGGCGGCGGGGCCGCCTTCGTGATGCCTCGCATGGTATTGCTGTTTGATTTGAAGAAAATCCGGCTAATATAC
GAATCAGTTTCAAAATATTT

Downstream 100 bases:

>100_bases
CGCGGAGGCGCGCGGCGCGGACCGTATCGATTGAAACAAGTTTCGGGGGAGGGAAGGGCCGATGTGTATTTTCCGCGGGG
ATTCGGGCTATAATCGCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MIKMVRVDDLQVFIRAADNGSLSAAARQLDLSPAVASAALKRLEQALGAQLLARSTRSLRLTLAGERYLEHARAALDALQ
AGSLALEQDRRELSGSLSLSMPSDLGRNLLRPWLDDFLRRHPGLSLQLQISDRVADLYRQPVDVALRYGVPEDSSLVALP
LAADNRRVLCASPDYLVRHGAPETPQALRGRQCLRLVLGAAVHERWSFERQGERQTVTVSGRWLSDDGEIVRRWAVDGCG
IAYKSRLDVLADLRAGRLTPLLPDYGTEPTPLCLVTPHRLMLSPAVAALRAHLQDCLERYLAEP

Sequences:

>Translated_304_residues
MIKMVRVDDLQVFIRAADNGSLSAAARQLDLSPAVASAALKRLEQALGAQLLARSTRSLRLTLAGERYLEHARAALDALQ
AGSLALEQDRRELSGSLSLSMPSDLGRNLLRPWLDDFLRRHPGLSLQLQISDRVADLYRQPVDVALRYGVPEDSSLVALP
LAADNRRVLCASPDYLVRHGAPETPQALRGRQCLRLVLGAAVHERWSFERQGERQTVTVSGRWLSDDGEIVRRWAVDGCG
IAYKSRLDVLADLRAGRLTPLLPDYGTEPTPLCLVTPHRLMLSPAVAALRAHLQDCLERYLAEP
>Mature_304_residues
MIKMVRVDDLQVFIRAADNGSLSAAARQLDLSPAVASAALKRLEQALGAQLLARSTRSLRLTLAGERYLEHARAALDALQ
AGSLALEQDRRELSGSLSLSMPSDLGRNLLRPWLDDFLRRHPGLSLQLQISDRVADLYRQPVDVALRYGVPEDSSLVALP
LAADNRRVLCASPDYLVRHGAPETPQALRGRQCLRLVLGAAVHERWSFERQGERQTVTVSGRWLSDDGEIVRRWAVDGCG
IAYKSRLDVLADLRAGRLTPLLPDYGTEPTPLCLVTPHRLMLSPAVAALRAHLQDCLERYLAEP

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=258, Percent_Identity=33.3333333333333, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=32.996632996633, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786401, Length=257, Percent_Identity=33.4630350194552, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789639, Length=272, Percent_Identity=33.0882352941176, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=28.0276816608997, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787589, Length=279, Percent_Identity=26.8817204301075, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786448, Length=251, Percent_Identity=30.2788844621514, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788706, Length=179, Percent_Identity=31.8435754189944, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787601, Length=175, Percent_Identity=25.7142857142857, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=173, Percent_Identity=31.2138728323699, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789173, Length=269, Percent_Identity=27.5092936802974, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33557; Mature: 33557

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKMVRVDDLQVFIRAADNGSLSAAARQLDLSPAVASAALKRLEQALGAQLLARSTRSLR
CEEEEEECCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTLAGERYLEHARAALDALQAGSLALEQDRRELSGSLSLSMPSDLGRNLLRPWLDDFLRR
EEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHH
HPGLSLQLQISDRVADLYRQPVDVALRYGVPEDSSLVALPLAADNRRVLCASPDYLVRHG
CCCCEEEEEEHHHHHHHHHCCHHHHEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHCC
APETPQALRGRQCLRLVLGAAVHERWSFERQGERQTVTVSGRWLSDDGEIVRRWAVDGCG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECEEECCCHHHHHHHHCCCCC
IAYKSRLDVLADLRAGRLTPLLPDYGTEPTPLCLVTPHRLMLSPAVAALRAHLQDCLERY
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LAEP
HCCC
>Mature Secondary Structure
MIKMVRVDDLQVFIRAADNGSLSAAARQLDLSPAVASAALKRLEQALGAQLLARSTRSLR
CEEEEEECCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTLAGERYLEHARAALDALQAGSLALEQDRRELSGSLSLSMPSDLGRNLLRPWLDDFLRR
EEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHH
HPGLSLQLQISDRVADLYRQPVDVALRYGVPEDSSLVALPLAADNRRVLCASPDYLVRHG
CCCCEEEEEEHHHHHHHHHCCHHHHEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHCC
APETPQALRGRQCLRLVLGAAVHERWSFERQGERQTVTVSGRWLSDDGEIVRRWAVDGCG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECEEECCCHHHHHHHHCCCCC
IAYKSRLDVLADLRAGRLTPLLPDYGTEPTPLCLVTPHRLMLSPAVAALRAHLQDCLERY
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LAEP
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]