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The map label for this gene is hrcA [H]

Identifier: 34497063

GI number: 34497063

Start: 1734960

End: 1736006

Strand: Direct

Name: hrcA [H]

Synonym: CV_1608

Alternate gene names: 34497063

Gene position: 1734960-1736006 (Clockwise)

Preceding gene: 34497056

Following gene: 34497064

Centisome position: 36.52

GC content: 66.19

Gene sequence:

>1047_bases
GTGCAGGATGTGTACAATGGGGACATGATGAACGAACGCGCCCAACATTTGCTGAAGGCGCTGATCGAACGGTACATCGC
CGACGGTCAGCCGGTCGCCTCCAAGACCCTGTCGCTGCTGCCCGGCGTGGAGCTGTCGTCGGCCACGGTGCGCAACGTGC
TGGCCGATCTGGAAAACATGGGCCTGATCGCCTCGCCGCACACCTCGGCGGGCCGGGTGCCCACTGCGCGCGGCTACCGG
TTGTTCGTCGACCGGCTGCTGACGATACGGCCGCTGGACGAGCTGTCGCGCCACGAACTGGAGGCCAATCTGCAGCCGGA
CAGCCCGCAGCGCATCGTGCAGGCGGCGTCGTCGCTGCTCTCCGAGCTGACCAGTTTCGCCGGCGTGGTGCTGACGCCGC
AGCGCAGCGACGTCGCTTTCCGCCAGATCGAATTTCTGCGCCTGTCCGAACGGCGGGTGCTGATGATACTGGTGACGCTG
GACGGCGACGTGCAGAACCATTTGCTGGTGACGGAGCGCGATTACACGCCGAGCGAGTTGATCGAGGCCGGCAATTTCAT
CAACCAGCATTACGCCGGCCAAGGGCTGAGCGCCGTCGCGCAGCGGGTGGAGAGCGAGCTCAAGCAGCTGCAGGGAGACA
TCGCCGAGCTGATGGCCGCCGCGGTGAAGCTTGGCCAGCAGACGCTGGCCAAGCGCAGCGAGGACGTGGTGGTCAGCGGC
GGCTCGCGCCTGCTGCAGGTGCACGACCTGTCCGACGACCTGTCGCGGCTGCGGGAGCTGTTCGGCGTGTTCGAGCGCAA
GACCGAGCTCTTGAAGCTGCTGGCGCAGGGCAGGGAGGCGCAGGGCGTGAACATTTTCATCGGCGAGGAGTCTGGAGTCA
TGACGCTGGACGAATGCTCGGTGGTGACCGCGCCCTACTGCATCAACGGCCAAGTGGTCGGCACGCTCGGCGTGGTCGGC
CCCACGCGCATGGCCTACGAGCGGGTGATCCCCATCGTCGACATCACCGCCCGCCTGGTCAGCAACGCGCTGTCCTTCCG
TGAATGA

Upstream 100 bases:

>100_bases
TGGGGGCGATTATCGCAGAAAAAAGCTGGGCCAACAGCAGCTTGGGGCCGCGGTTTTCGTGCCATGGTCGTAAAGCCGCG
CCACGGCCCCTTTTGGCGCG

Downstream 100 bases:

>100_bases
ATCCGAGCCATACCCAAAAGAAAGCAGAATCATGAAATCGATGTTGAAACTGGCCATCGCCGCCGCCCTGGCCGGCGCGG
CCCTCACCGCCCCGCCAGCC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MQDVYNGDMMNERAQHLLKALIERYIADGQPVASKTLSLLPGVELSSATVRNVLADLENMGLIASPHTSAGRVPTARGYR
LFVDRLLTIRPLDELSRHELEANLQPDSPQRIVQAASSLLSELTSFAGVVLTPQRSDVAFRQIEFLRLSERRVLMILVTL
DGDVQNHLLVTERDYTPSELIEAGNFINQHYAGQGLSAVAQRVESELKQLQGDIAELMAAAVKLGQQTLAKRSEDVVVSG
GSRLLQVHDLSDDLSRLRELFGVFERKTELLKLLAQGREAQGVNIFIGEESGVMTLDECSVVTAPYCINGQVVGTLGVVG
PTRMAYERVIPIVDITARLVSNALSFRE

Sequences:

>Translated_348_residues
MQDVYNGDMMNERAQHLLKALIERYIADGQPVASKTLSLLPGVELSSATVRNVLADLENMGLIASPHTSAGRVPTARGYR
LFVDRLLTIRPLDELSRHELEANLQPDSPQRIVQAASSLLSELTSFAGVVLTPQRSDVAFRQIEFLRLSERRVLMILVTL
DGDVQNHLLVTERDYTPSELIEAGNFINQHYAGQGLSAVAQRVESELKQLQGDIAELMAAAVKLGQQTLAKRSEDVVVSG
GSRLLQVHDLSDDLSRLRELFGVFERKTELLKLLAQGREAQGVNIFIGEESGVMTLDECSVVTAPYCINGQVVGTLGVVG
PTRMAYERVIPIVDITARLVSNALSFRE
>Mature_348_residues
MQDVYNGDMMNERAQHLLKALIERYIADGQPVASKTLSLLPGVELSSATVRNVLADLENMGLIASPHTSAGRVPTARGYR
LFVDRLLTIRPLDELSRHELEANLQPDSPQRIVQAASSLLSELTSFAGVVLTPQRSDVAFRQIEFLRLSERRVLMILVTL
DGDVQNHLLVTERDYTPSELIEAGNFINQHYAGQGLSAVAQRVESELKQLQGDIAELMAAAVKLGQQTLAKRSEDVVVSG
GSRLLQVHDLSDDLSRLRELFGVFERKTELLKLLAQGREAQGVNIFIGEESGVMTLDECSVVTAPYCINGQVVGTLGVVG
PTRMAYERVIPIVDITARLVSNALSFRE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38229; Mature: 38229

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVYNGDMMNERAQHLLKALIERYIADGQPVASKTLSLLPGVELSSATVRNVLADLENM
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GLIASPHTSAGRVPTARGYRLFVDRLLTIRPLDELSRHELEANLQPDSPQRIVQAASSLL
CEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
SELTSFAGVVLTPQRSDVAFRQIEFLRLSERRVLMILVTLDGDVQNHLLVTERDYTPSEL
HHHHHHCCEEECCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEECCCCHHHH
IEAGNFINQHYAGQGLSAVAQRVESELKQLQGDIAELMAAAVKLGQQTLAKRSEDVVVSG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GSRLLQVHDLSDDLSRLRELFGVFERKTELLKLLAQGREAQGVNIFIGEESGVMTLDECS
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCC
VVTAPYCINGQVVGTLGVVGPTRMAYERVIPIVDITARLVSNALSFRE
EEECCEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQDVYNGDMMNERAQHLLKALIERYIADGQPVASKTLSLLPGVELSSATVRNVLADLENM
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GLIASPHTSAGRVPTARGYRLFVDRLLTIRPLDELSRHELEANLQPDSPQRIVQAASSLL
CEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
SELTSFAGVVLTPQRSDVAFRQIEFLRLSERRVLMILVTLDGDVQNHLLVTERDYTPSEL
HHHHHHCCEEECCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEECCCCHHHH
IEAGNFINQHYAGQGLSAVAQRVESELKQLQGDIAELMAAAVKLGQQTLAKRSEDVVVSG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GSRLLQVHDLSDDLSRLRELFGVFERKTELLKLLAQGREAQGVNIFIGEESGVMTLDECS
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCCC
VVTAPYCINGQVVGTLGVVGPTRMAYERVIPIVDITARLVSNALSFRE
EEECCEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]