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The map label for this gene is nudL [H]

Identifier: 34497041

GI number: 34497041

Start: 1709998

End: 1710609

Strand: Direct

Name: nudL [H]

Synonym: CV_1586

Alternate gene names: 34497041

Gene position: 1709998-1710609 (Clockwise)

Preceding gene: 34497040

Following gene: 34497044

Centisome position: 35.99

GC content: 70.1

Gene sequence:

>612_bases
ATGTGGTCTATGGAGGCAGACAAGGCCGCCGCGCTGATCGCCGGGCGGCTGCAGTCCTATGATTTCACCGGCAGGGTGGC
CGATCTGCCTTACCGGGCGGCGTCGCCGGGCTTGAAGCCGGCCGCGGTGCTGGTCCCGCTGGTATGGCATGCGGACGGGG
CCACCGTGCTGTTCACCCGCCGCACCGAGCACCTGTCCAGCCATCCCGGCCAGGTCAGCTTTCCCGGCGGCAAGCTGGAG
AGCGGCGACGCTTCCGCCCAGGCGGCGGCGCTGCGCGAGGCGCGCGAGGAAACCGGCTTGCCCGAATCGTCGGTATGGGT
GCTGGGCAATCTGCCGGACTACGTGACGGTGACCGGCTACGTGGTGACGCCGGTGGTGGGCTTGCTGAATCCGCCGCTGG
CGCTGGCGCCGGCGCCGGACGAGGTGGCCGAGGTGTTCGAAGTGCCGCTGCCCCTGCTGCTGGACAGGCAGGCTTACAGC
CGCCATGACTACGTGCGCGACGGGGTGGCCGGACAGTACCTGTCGCTGCAATGGGACCGACACACGATCTGGGGTGCGAC
CGCGGCGATGATGTGGATGCTGGCGGACGCGCTGGGCGGCGCGTCCGTCTAG

Upstream 100 bases:

>100_bases
CGCCAAGATGCCAGACCATGCCGGTCTGGCATTTTTTTTGGTACATTGGAGGGAGGTCCGCCGGGAAGAGCGGATGCCGG
GAGGCAAAAGGATAACGATT

Downstream 100 bases:

>100_bases
CGCCTGGCGTCGCCAGGGGCGACGTCGCGCATCGGCGCAAAGCCGCGGCAAGGCGATGGCGGGGAGGCTTGGCTGGGATG
CCGCCGCGCGGCCTGGCGCC

Product: MutT/nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MWSMEADKAAALIAGRLQSYDFTGRVADLPYRAASPGLKPAAVLVPLVWHADGATVLFTRRTEHLSSHPGQVSFPGGKLE
SGDASAQAAALREAREETGLPESSVWVLGNLPDYVTVTGYVVTPVVGLLNPPLALAPAPDEVAEVFEVPLPLLLDRQAYS
RHDYVRDGVAGQYLSLQWDRHTIWGATAAMMWMLADALGGASV

Sequences:

>Translated_203_residues
MWSMEADKAAALIAGRLQSYDFTGRVADLPYRAASPGLKPAAVLVPLVWHADGATVLFTRRTEHLSSHPGQVSFPGGKLE
SGDASAQAAALREAREETGLPESSVWVLGNLPDYVTVTGYVVTPVVGLLNPPLALAPAPDEVAEVFEVPLPLLLDRQAYS
RHDYVRDGVAGQYLSLQWDRHTIWGATAAMMWMLADALGGASV
>Mature_203_residues
MWSMEADKAAALIAGRLQSYDFTGRVADLPYRAASPGLKPAAVLVPLVWHADGATVLFTRRTEHLSSHPGQVSFPGGKLE
SGDASAQAAALREAREETGLPESSVWVLGNLPDYVTVTGYVVTPVVGLLNPPLALAPAPDEVAEVFEVPLPLLLDRQAYS
RHDYVRDGVAGQYLSLQWDRHTIWGATAAMMWMLADALGGASV

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=155, Percent_Identity=40, Blast_Score=101, Evalue=4e-22,
Organism=Escherichia coli, GI1788115, Length=161, Percent_Identity=44.0993788819876, Blast_Score=98, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17510677, Length=182, Percent_Identity=34.0659340659341, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17536993, Length=124, Percent_Identity=35.4838709677419, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859683, Length=163, Percent_Identity=34.9693251533742, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 21720; Mature: 21720

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSMEADKAAALIAGRLQSYDFTGRVADLPYRAASPGLKPAAVLVPLVWHADGATVLFTR
CCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHEEEEEEECCCCEEEEEE
RTEHLSSHPGQVSFPGGKLESGDASAQAAALREAREETGLPESSVWVLGNLPDYVTVTGY
CHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECHH
VVTPVVGLLNPPLALAPAPDEVAEVFEVPLPLLLDRQAYSRHDYVRDGVAGQYLSLQWDR
HHHHHHHHCCCCCEECCCCHHHHHHHHCCCHHEECCHHHHHHHHHHCCCCCCEEEEEECC
HTIWGATAAMMWMLADALGGASV
CCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MWSMEADKAAALIAGRLQSYDFTGRVADLPYRAASPGLKPAAVLVPLVWHADGATVLFTR
CCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCHHHHEEEEEEECCCCEEEEEE
RTEHLSSHPGQVSFPGGKLESGDASAQAAALREAREETGLPESSVWVLGNLPDYVTVTGY
CHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECHH
VVTPVVGLLNPPLALAPAPDEVAEVFEVPLPLLLDRQAYSRHDYVRDGVAGQYLSLQWDR
HHHHHHHHCCCCCEECCCCHHHHHHHHCCCHHEECCHHHHHHHHHHCCCCCCEEEEEECC
HTIWGATAAMMWMLADALGGASV
CCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]