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The map label for this gene is cysQ [H]

Identifier: 34497032

GI number: 34497032

Start: 1694365

End: 1695114

Strand: Reverse

Name: cysQ [H]

Synonym: CV_1577

Alternate gene names: 34497032

Gene position: 1695114-1694365 (Counterclockwise)

Preceding gene: 34497033

Following gene: 34497030

Centisome position: 35.68

GC content: 74.13

Gene sequence:

>750_bases
ATGCCGGACGACCATCAGCTCGCCGCCCACATCGCGGCAGCCGCCGCCCAACGATTGCTCGACCTACGCCGCCGCCATCC
GGAAGGCGGCAAGGCGCTGGGCGCGCGCGGCGACGCCGAAGCCAACGCCCTGATTCTGGATATGCTGCGCGCGGCGCGGC
CGGATGACGGCCTGCTGTCCGAGGAATCCATGCCGGATCCCGCCCGCCTGGGCCAGCGTCGGGTGTGGATCGTCGACCCG
CTGGACGGCACCCGCGAATATTGCGAGCCAGGCCGCGACGACTGGGCGGTGCACGTCGCGCTGGCGCTGGACGGCGCGCC
CGCCGCCGCCGCCGTGGCGCTGCCCGCGCGCGGCGAGTTGTTCTCCACGCCCGACCCCCGGCTTGCCGCCGCGCCGCCAG
GCCGGCTGAAAATCCTGGTCAGCCGCAGCCGCGCGCCGGCGCTGGCCGAACGCGTCGCCGCCCGGCTGGACGCCGAGCTG
GTCCCGATGGGATCGGCCGGCGCCAAGGCGATGTCGGCGCTGCGCGGCGAAGCCCACGCCTATCTGCACGCCGGGGGCAT
GAACGAATGGGACACCTGCGCGCCGGTGGGCGTGGCGCTGGCCGCCGGCCTCTACGCGTCGCGGATAGACGGCTCGCCCT
GCGCGTTCAACCAGGCGGACGTGAAGATGCCGGACCTGCTGATCTGCCGGCCGGAACTGGCGGAGACGCTGCTGGCGGCG
ATAACGGCGGAGCGGATGCCGGGCGATTGA

Upstream 100 bases:

>100_bases
CGGGGCCAGCCCGCAGCCCGGCGTGGAATACTTCTGACGCCGGCATTGCCGCGCGCGCCGATACCGTGTATCACTCCGGC
ATCGACGCCAGGAGCCCCCC

Downstream 100 bases:

>100_bases
ACACCGCTGGGCCAAGCTTGCGCCGCGCCCGGTCCACGACGCGCCGGCGCAGGCGGCGCAAGTCGTGCGACCGGCAGGCG
CAGCGCAGGGGTTTGCTCAG

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: PAP phosphatase; 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; D-fructose-1,6-bisphosphate 1-phosphohydrolase; DPNPase; Fructose-1,6-bisphosphatase; FBPase; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MPDDHQLAAHIAAAAAQRLLDLRRRHPEGGKALGARGDAEANALILDMLRAARPDDGLLSEESMPDPARLGQRRVWIVDP
LDGTREYCEPGRDDWAVHVALALDGAPAAAAVALPARGELFSTPDPRLAAAPPGRLKILVSRSRAPALAERVAARLDAEL
VPMGSAGAKAMSALRGEAHAYLHAGGMNEWDTCAPVGVALAAGLYASRIDGSPCAFNQADVKMPDLLICRPELAETLLAA
ITAERMPGD

Sequences:

>Translated_249_residues
MPDDHQLAAHIAAAAAQRLLDLRRRHPEGGKALGARGDAEANALILDMLRAARPDDGLLSEESMPDPARLGQRRVWIVDP
LDGTREYCEPGRDDWAVHVALALDGAPAAAAVALPARGELFSTPDPRLAAAPPGRLKILVSRSRAPALAERVAARLDAEL
VPMGSAGAKAMSALRGEAHAYLHAGGMNEWDTCAPVGVALAAGLYASRIDGSPCAFNQADVKMPDLLICRPELAETLLAA
ITAERMPGD
>Mature_248_residues
PDDHQLAAHIAAAAAQRLLDLRRRHPEGGKALGARGDAEANALILDMLRAARPDDGLLSEESMPDPARLGQRRVWIVDPL
DGTREYCEPGRDDWAVHVALALDGAPAAAAVALPARGELFSTPDPRLAAAPPGRLKILVSRSRAPALAERVAARLDAELV
PMGSAGAKAMSALRGEAHAYLHAGGMNEWDTCAPVGVALAAGLYASRIDGSPCAFNQADVKMPDLLICRPELAETLLAAI
TAERMPGD

Specific function: Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can ser

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Localized On The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=168, Percent_Identity=30.952380952381, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71995905, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71995897, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24651149, Length=231, Percent_Identity=29.4372294372294, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7; =3.1.3.11; =3.1.3.25 [H]

Molecular weight: Translated: 26174; Mature: 26043

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDHQLAAHIAAAAAQRLLDLRRRHPEGGKALGARGDAEANALILDMLRAARPDDGLLS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
EESMPDPARLGQRRVWIVDPLDGTREYCEPGRDDWAVHVALALDGAPAAAAVALPARGEL
CCCCCCHHHHCCCEEEEECCCCCCHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCCCCC
FSTPDPRLAAAPPGRLKILVSRSRAPALAERVAARLDAELVPMGSAGAKAMSALRGEAHA
CCCCCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCEECCCCCHHHHHHHHHCCCEE
YLHAGGMNEWDTCAPVGVALAAGLYASRIDGSPCAFNQADVKMPDLLICRPELAETLLAA
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHH
ITAERMPGD
HHHHCCCCC
>Mature Secondary Structure 
PDDHQLAAHIAAAAAQRLLDLRRRHPEGGKALGARGDAEANALILDMLRAARPDDGLLS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
EESMPDPARLGQRRVWIVDPLDGTREYCEPGRDDWAVHVALALDGAPAAAAVALPARGEL
CCCCCCHHHHCCCEEEEECCCCCCHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCCCCC
FSTPDPRLAAAPPGRLKILVSRSRAPALAERVAARLDAELVPMGSAGAKAMSALRGEAHA
CCCCCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCEECCCCCHHHHHHHHHCCCEE
YLHAGGMNEWDTCAPVGVALAAGLYASRIDGSPCAFNQADVKMPDLLICRPELAETLLAA
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHH
ITAERMPGD
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]