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The map label for this gene is agaR [H]

Identifier: 34496980

GI number: 34496980

Start: 1632161

End: 1632874

Strand: Reverse

Name: agaR [H]

Synonym: CV_1525

Alternate gene names: 34496980

Gene position: 1632874-1632161 (Counterclockwise)

Preceding gene: 34496982

Following gene: 34496979

Centisome position: 34.37

GC content: 69.47

Gene sequence:

>714_bases
CTGCACGGCAGGGTCTCCGCCGGCGAACTGGCGGCGGTGCTGCGCGTGTCCGAGGACTCCATCCGCCGCGATCTGCGCGA
ACTGGCTGCCGACGGCGCTTGCCAGCGCGTGTACGGCGGCGCCATCGCGCTGACGCCGAATCGCCACGGCTTCCAGCAAC
GCCGCCATGAGAACACCGAACGCAAGGCCAGGCTGGCCGCGGCGGCGGTGCGGCTGCTCAAGCCCGGCCAATTCGTGTTC
CTGGACGGCGGCACCACCAATCTGGAAATCGCCCGCGCGCTGCCGGAGCATCTGCCGCTGACGGTGGCCACCAATTCCAT
CCCCATCGCCGCCGCGCTGTTCGGACAAAAACAACTGTCGGTGCTGGTGCTGGGCGGCAACCTCAACCACCTGAGCGGCG
ACGCGCTGGGCGCCATCGCCAGCCGGATGCTGGGCACCATGCGGCCGGACATCTGCTTTCTCGGCACCTGCTCGGTCGAC
TGCGAGCTGGGCGTGGGCACGGTGATCGCCGACGAAGCCGCGTTCAAGCGCCAGTTGGTCGAGCAATGCGGCCACACCGT
GCTGGCCGTCACCAACGAGAAGCTGGACACCGCCTCGCCCTTCATCGTCGCCCCGCTGTCCGACATCGGCACCCTGATCA
TCGAGCCCGATGCCGACCCGGCGCGGCGCGCCCATCTGGAAGCGGCAGGCGCGCCCTTGCTGATCGCGGACTGA

Upstream 100 bases:

>100_bases
TGCCGGCATTCCGTTCACGCCAGTCCGCCTCATGTCCAGAGAACGCCCAAGCGCCAGCCAGCCTTCCGACCGCCATCACT
ACATCCGCGAGCAGCTGCGG

Downstream 100 bases:

>100_bases
CTCGACACCCCATCGGCATATTGCCTCCAATCAAACATTTGTTTTAAAGTTCTGCACGGCGCGCCGCCTCGATAAAACCA
TTACAAATCAGCGCGCTTTG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MHGRVSAGELAAVLRVSEDSIRRDLRELAADGACQRVYGGAIALTPNRHGFQQRRHENTERKARLAAAAVRLLKPGQFVF
LDGGTTNLEIARALPEHLPLTVATNSIPIAAALFGQKQLSVLVLGGNLNHLSGDALGAIASRMLGTMRPDICFLGTCSVD
CELGVGTVIADEAAFKRQLVEQCGHTVLAVTNEKLDTASPFIVAPLSDIGTLIIEPDADPARRAHLEAAGAPLLIAD

Sequences:

>Translated_237_residues
MHGRVSAGELAAVLRVSEDSIRRDLRELAADGACQRVYGGAIALTPNRHGFQQRRHENTERKARLAAAAVRLLKPGQFVF
LDGGTTNLEIARALPEHLPLTVATNSIPIAAALFGQKQLSVLVLGGNLNHLSGDALGAIASRMLGTMRPDICFLGTCSVD
CELGVGTVIADEAAFKRQLVEQCGHTVLAVTNEKLDTASPFIVAPLSDIGTLIIEPDADPARRAHLEAAGAPLLIAD
>Mature_237_residues
MHGRVSAGELAAVLRVSEDSIRRDLRELAADGACQRVYGGAIALTPNRHGFQQRRHENTERKARLAAAAVRLLKPGQFVF
LDGGTTNLEIARALPEHLPLTVATNSIPIAAALFGQKQLSVLVLGGNLNHLSGDALGAIASRMLGTMRPDICFLGTCSVD
CELGVGTVIADEAAFKRQLVEQCGHTVLAVTNEKLDTASPFIVAPLSDIGTLIIEPDADPARRAHLEAAGAPLLIAD

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=219, Percent_Identity=32.4200913242009, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789829, Length=194, Percent_Identity=29.8969072164948, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1789059, Length=237, Percent_Identity=28.2700421940928, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI226510968, Length=217, Percent_Identity=29.9539170506912, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788069, Length=217, Percent_Identity=27.6497695852535, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082344, Length=214, Percent_Identity=26.1682242990654, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790635, Length=240, Percent_Identity=25.4166666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789170, Length=217, Percent_Identity=24.8847926267281, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787540, Length=238, Percent_Identity=25.6302521008403, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787063, Length=194, Percent_Identity=28.8659793814433, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 25036; Mature: 25036

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGRVSAGELAAVLRVSEDSIRRDLRELAADGACQRVYGGAIALTPNRHGFQQRRHENTE
CCCCCCHHHHHHEEEECHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCCCHHHHHHCCHH
RKARLAAAAVRLLKPGQFVFLDGGTTNLEIARALPEHLPLTVATNSIPIAAALFGQKQLS
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCHHHCCEEEECCCCCCHHHHHCCCCEE
VLVLGGNLNHLSGDALGAIASRMLGTMRPDICFLGTCSVDCELGVGTVIADEAAFKRQLV
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEHHHHHHHHHH
EQCGHTVLAVTNEKLDTASPFIVAPLSDIGTLIIEPDADPARRAHLEAAGAPLLIAD
HHCCCEEEEEECCCCCCCCCEEEEEHHHCCEEEECCCCCHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MHGRVSAGELAAVLRVSEDSIRRDLRELAADGACQRVYGGAIALTPNRHGFQQRRHENTE
CCCCCCHHHHHHEEEECHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCCCHHHHHHCCHH
RKARLAAAAVRLLKPGQFVFLDGGTTNLEIARALPEHLPLTVATNSIPIAAALFGQKQLS
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCHHHCCEEEECCCCCCHHHHHCCCCEE
VLVLGGNLNHLSGDALGAIASRMLGTMRPDICFLGTCSVDCELGVGTVIADEAAFKRQLV
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEHHHHHHHHHH
EQCGHTVLAVTNEKLDTASPFIVAPLSDIGTLIIEPDADPARRAHLEAAGAPLLIAD
HHCCCEEEEEECCCCCCCCCEEEEEHHHCCEEEECCCCCHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]