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The map label for this gene is mocR [H]

Identifier: 34496972

GI number: 34496972

Start: 1623555

End: 1624985

Strand: Reverse

Name: mocR [H]

Synonym: CV_1517

Alternate gene names: 34496972

Gene position: 1624985-1623555 (Counterclockwise)

Preceding gene: 34496975

Following gene: 34496971

Centisome position: 34.2

GC content: 73.17

Gene sequence:

>1431_bases
ATGATTCCCTCCGCGTTCCAGTTCCCCTTGCTGCGCGAGCACGCGCCGCCGCTGCACCGGCAGCTTTACCTGCGCATCCG
CGAAGCCATCCTGGCCGGCCAGCTGCCGCCGGGCGCCCGCCTGCCGGCCACGCGGGTGCTGGCCGCCGATCTGGGCGTCT
CGCGCGGCACCGTCGACCAGGCTTACGGCCAACTGCTGGCGGAGGGCTTTCTGCTCAGCCGCGCCGCCGCCGGCACCGTG
ATCCATCCCGAACTGGCCTCCCGTCTTGGCAGCCCGCCGGTTCGCCACGACTCCGCGCCCGGTCCCCGGCAAATCCGGAC
GGGCGCGCCAGAAGCGGACCTGCCACCGCCCTTCCAGCTGGGCCTGCCCGCGCTGGACGCCTTCCCGCGCAAGCTGTGGG
CGCGGCTGGCCGGCCGCCGCGCCAGGGCCTTGCCGTTGTCCGGGCTGAATTATCCCGATGCGGCCGGCTATCCGCCGCTG
CGCGAGGCCATCGTCCGCCACCTGGCCTTGTTCCGCGGCATTCAGTGCTCCGCTGATCAGGTATTCATCACCAGCGGCTT
CCAAGGCGCGCTGGCGCTGGCGATGCGAACCCTGCTGCGCCCTGGCGACCCGGTCTGGATGGAGGATCCGGGCTATTTCC
GCGCCAGCGGCGCGCTGAGGCTGGGCGGCGCCACGCTGGTGCCGGCGCCGGTGGACCGGAACGGGCTGCGCGTGGACGAG
GCGATGCGGCGCGCGCCTCACGCGCGGATGGCCTACTGCACGCCGTCGCACCACGCCCCGCTAGGCGTCGCCCTGTCGCT
GCCGCGCCGGCTCGAGCTGCTGGGCTGGGCGGAAAAACAGCAGGCCTGGATCGTCGAGGACGACTACGACGGCGAATTCC
GCTACCACGGCCCGCCGCTGCCCGCGCTGCGCAGCCTGGATCGCGCCGGACGGGTGCTTTACGTCGGCAGCTTCAGCAAA
ACCTTGTTTCCCGGACTGCGCCTGGGCTATCTGGTGGCGCCGGCCAGCGAAGCTCCCCGCTTCGCCCAGGCCTGCGATCT
GCTCTCCCCCGCGCCGTCCATCCAGGACCAGGCGACGACGGCCGACTTCCTGAGCCAGGGCCACTTCGCCCGCCACATCA
AGCGGATGCGCGCGCTCTACGCCCAGCGCCGCGCCGCGCTGGCCGCCGCCTTGCAGGCGGAATGCGGCGATCGGCTGCGG
CTGGACGGCCAGCCGGTAGGCCTGCAAGTCACCGTCTGGCTGCCGGACGGCGAAGACGACCGCGCCGTCGCCGCGCGCCT
GCAAGCCAAGGGATTGGCGGGCCAGCCGCTGTCCGCCTTCTGCCTGGAAGGCGGCCATCCTCCCGCGCTGCTGCTCGGCT
TCGCCAATGTGCCGGCCGAGCGCGCGCCCGCGCTGGCGCGGCGGTTCAGGGAGGCGCTGGACGCGCGCTAG

Upstream 100 bases:

>100_bases
TCCATTGTCATTCCTTGTCGGTCGGCGGTTTGGCTTCCCGGCAAGATACCGGCGGCATGGTACAATGATGAGAGCCAAAA
ATCGTCAAAACCAATAGGCC

Downstream 100 bases:

>100_bases
CCATGGGCCTAAGCGGCTTCTGCTATAATCGCCCACTCCTCATTCATCATCGTTCTTTGACGCCGCATGACCACCGCCCC
GCTTCTGGCCGAACTCAAGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MIPSAFQFPLLREHAPPLHRQLYLRIREAILAGQLPPGARLPATRVLAADLGVSRGTVDQAYGQLLAEGFLLSRAAAGTV
IHPELASRLGSPPVRHDSAPGPRQIRTGAPEADLPPPFQLGLPALDAFPRKLWARLAGRRARALPLSGLNYPDAAGYPPL
REAIVRHLALFRGIQCSADQVFITSGFQGALALAMRTLLRPGDPVWMEDPGYFRASGALRLGGATLVPAPVDRNGLRVDE
AMRRAPHARMAYCTPSHHAPLGVALSLPRRLELLGWAEKQQAWIVEDDYDGEFRYHGPPLPALRSLDRAGRVLYVGSFSK
TLFPGLRLGYLVAPASEAPRFAQACDLLSPAPSIQDQATTADFLSQGHFARHIKRMRALYAQRRAALAAALQAECGDRLR
LDGQPVGLQVTVWLPDGEDDRAVAARLQAKGLAGQPLSAFCLEGGHPPALLLGFANVPAERAPALARRFREALDAR

Sequences:

>Translated_476_residues
MIPSAFQFPLLREHAPPLHRQLYLRIREAILAGQLPPGARLPATRVLAADLGVSRGTVDQAYGQLLAEGFLLSRAAAGTV
IHPELASRLGSPPVRHDSAPGPRQIRTGAPEADLPPPFQLGLPALDAFPRKLWARLAGRRARALPLSGLNYPDAAGYPPL
REAIVRHLALFRGIQCSADQVFITSGFQGALALAMRTLLRPGDPVWMEDPGYFRASGALRLGGATLVPAPVDRNGLRVDE
AMRRAPHARMAYCTPSHHAPLGVALSLPRRLELLGWAEKQQAWIVEDDYDGEFRYHGPPLPALRSLDRAGRVLYVGSFSK
TLFPGLRLGYLVAPASEAPRFAQACDLLSPAPSIQDQATTADFLSQGHFARHIKRMRALYAQRRAALAAALQAECGDRLR
LDGQPVGLQVTVWLPDGEDDRAVAARLQAKGLAGQPLSAFCLEGGHPPALLLGFANVPAERAPALARRFREALDAR
>Mature_476_residues
MIPSAFQFPLLREHAPPLHRQLYLRIREAILAGQLPPGARLPATRVLAADLGVSRGTVDQAYGQLLAEGFLLSRAAAGTV
IHPELASRLGSPPVRHDSAPGPRQIRTGAPEADLPPPFQLGLPALDAFPRKLWARLAGRRARALPLSGLNYPDAAGYPPL
REAIVRHLALFRGIQCSADQVFITSGFQGALALAMRTLLRPGDPVWMEDPGYFRASGALRLGGATLVPAPVDRNGLRVDE
AMRRAPHARMAYCTPSHHAPLGVALSLPRRLELLGWAEKQQAWIVEDDYDGEFRYHGPPLPALRSLDRAGRVLYVGSFSK
TLFPGLRLGYLVAPASEAPRFAQACDLLSPAPSIQDQATTADFLSQGHFARHIKRMRALYAQRRAALAAALQAECGDRLR
LDGQPVGLQVTVWLPDGEDDRAVAARLQAKGLAGQPLSAFCLEGGHPPALLLGFANVPAERAPALARRFREALDAR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=225, Percent_Identity=26.2222222222222, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI33469970, Length=225, Percent_Identity=26.2222222222222, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1790797, Length=461, Percent_Identity=29.0672451193059, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=31.2335958005249, Blast_Score=131, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6321236, Length=259, Percent_Identity=25.0965250965251, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51494; Mature: 51494

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSAFQFPLLREHAPPLHRQLYLRIREAILAGQLPPGARLPATRVLAADLGVSRGTVDQ
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHH
AYGQLLAEGFLLSRAAAGTVIHPELASRLGSPPVRHDSAPGPRQIRTGAPEADLPPPFQL
HHHHHHHHHHHHHHHCCCCEECHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHC
GLPALDAFPRKLWARLAGRRARALPLSGLNYPDAAGYPPLREAIVRHLALFRGIQCSADQ
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
VFITSGFQGALALAMRTLLRPGDPVWMEDPGYFRASGALRLGGATLVPAPVDRNGLRVDE
EEEECCCHHHHHHHHHHHHCCCCCCEECCCCCEEECCCEEECCCEEECCCCCCCCCCHHH
AMRRAPHARMAYCTPSHHAPLGVALSLPRRLELLGWAEKQQAWIVEDDYDGEFRYHGPPL
HHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHHCCCCCCCEEEEECCCCCCEEECCCCC
PALRSLDRAGRVLYVGSFSKTLFPGLRLGYLVAPASEAPRFAQACDLLSPAPSIQDQATT
HHHHHHHHCCCEEEEECCHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHH
ADFLSQGHFARHIKRMRALYAQRRAALAAALQAECGDRLRLDGQPVGLQVTVWLPDGEDD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCC
RAVAARLQAKGLAGQPLSAFCLEGGHPPALLLGFANVPAERAPALARRFREALDAR
HHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPSAFQFPLLREHAPPLHRQLYLRIREAILAGQLPPGARLPATRVLAADLGVSRGTVDQ
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHH
AYGQLLAEGFLLSRAAAGTVIHPELASRLGSPPVRHDSAPGPRQIRTGAPEADLPPPFQL
HHHHHHHHHHHHHHHCCCCEECHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHC
GLPALDAFPRKLWARLAGRRARALPLSGLNYPDAAGYPPLREAIVRHLALFRGIQCSADQ
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
VFITSGFQGALALAMRTLLRPGDPVWMEDPGYFRASGALRLGGATLVPAPVDRNGLRVDE
EEEECCCHHHHHHHHHHHHCCCCCCEECCCCCEEECCCEEECCCEEECCCCCCCCCCHHH
AMRRAPHARMAYCTPSHHAPLGVALSLPRRLELLGWAEKQQAWIVEDDYDGEFRYHGPPL
HHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHHCCCCCCCEEEEECCCCCCEEECCCCC
PALRSLDRAGRVLYVGSFSKTLFPGLRLGYLVAPASEAPRFAQACDLLSPAPSIQDQATT
HHHHHHHHCCCEEEEECCHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHH
ADFLSQGHFARHIKRMRALYAQRRAALAAALQAECGDRLRLDGQPVGLQVTVWLPDGEDD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCC
RAVAARLQAKGLAGQPLSAFCLEGGHPPALLLGFANVPAERAPALARRFREALDAR
HHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]