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The map label for this gene is ephB [H]

Identifier: 34496949

GI number: 34496949

Start: 1597226

End: 1598257

Strand: Reverse

Name: ephB [H]

Synonym: CV_1494

Alternate gene names: 34496949

Gene position: 1598257-1597226 (Counterclockwise)

Preceding gene: 34496957

Following gene: 34496946

Centisome position: 33.64

GC content: 68.22

Gene sequence:

>1032_bases
ATGAAAAAAACCATCGACAGCAAGCGCCGCAACCTCCTCGCCGCAATCGCGCTTTCCCTGGCGGGCGCGTTCGCGCTGGC
GGAAACAACCAACGCCGCGCCGGACGCCACGGCGATCGCAGCGCAAGCGCTGCCCACCTTCAAAACCATCAGGCAGATCG
ACGCCGGCGCGCTGAACATCGGCTACGTCGACGAAGGCCCGGCCGACGGCCCGGCTGTCATCCTGCTGCACGGCTGGCCG
TACGACATCCACAGCTTCATCGACGTCGTCCCGATGCTGACCCGGTCCGGCTACCGCGTGATCGTGCCATACCTGCGCGG
CTACGGCAGCACGCGCTTTCGCGACGCAGGCGCCGTGCGCAACGGCCAGCCGGCGGCGCTGGCTTCCGACGTCGTCGCGT
TGATGGACGCGCTGAAGATAGACAAGGCCATCCTCGCCGGCTACGACTGGGGCGCGCGCTCCGCCGACATCGTCGCCGCG
CTGTGGCCGCAGCGGGTGAAGGGGCTGGTTGCCGTCAGCGGCTACCTGATAGGCAGCCAGGAAGCCGGCAAGCAACCGTT
GCCGCCCAAGGCCGAGCTGCAATGGTGGTACCAGTTCTACTTCGCCACCGAGCGCGGCCGCGCCGGCTACGACAAGAACC
ATCGCGATTTCGCCAGGCTGATCTGGCAAACCGCCTCGCCGCGGTGGCATTTCGACGACGCCGTCTTCGAGCGCAGCGCC
GCGGCGCTGGACAACCCGGACCACGTCGCCGTCACTCTCTACAACTATCGCTGGCGCCTGGGCCTGGAAACCGGCGAAGC
CAAGTACGCCGACTGGGAAGCGCGCCTGGCCACCTTCCCCGCCATCGCGGTGCCGACCATCACCATGGAGGGCGACGCCA
ACGGCGCGCCGCACCCCGAGCCGGCCGCGTACGCCAAGCGCTTCACCGGCAAGTACAAGCACCTGCTGATCCGCGGCGGC
GTGGGACACAACCTGCCGCAGGAAGCGCCGCGCGCCTTCGCCGATGCGATGATCGAGGTCGATCACCTCTGA

Upstream 100 bases:

>100_bases
ACCTGCCCGGAGCGCCGGCCGAACGACGCCAGCGCGCAGCGCCGGTCATCCCGCTCCATGGATGCGCGATACCCCACCCA
ACCACCACAGGTGAAACAAG

Downstream 100 bases:

>100_bases
GCGAGACGCCGCCGATGACCGACAACAACCCTGTCAACGCATGGCCATGACTGGCCGACGTGACCTTAAGCCTGCGCGCT
CAGCGGCGTGGCGAAGCCGA

Product: epoxide hydrolase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKKTIDSKRRNLLAAIALSLAGAFALAETTNAAPDATAIAAQALPTFKTIRQIDAGALNIGYVDEGPADGPAVILLHGWP
YDIHSFIDVVPMLTRSGYRVIVPYLRGYGSTRFRDAGAVRNGQPAALASDVVALMDALKIDKAILAGYDWGARSADIVAA
LWPQRVKGLVAVSGYLIGSQEAGKQPLPPKAELQWWYQFYFATERGRAGYDKNHRDFARLIWQTASPRWHFDDAVFERSA
AALDNPDHVAVTLYNYRWRLGLETGEAKYADWEARLATFPAIAVPTITMEGDANGAPHPEPAAYAKRFTGKYKHLLIRGG
VGHNLPQEAPRAFADAMIEVDHL

Sequences:

>Translated_343_residues
MKKTIDSKRRNLLAAIALSLAGAFALAETTNAAPDATAIAAQALPTFKTIRQIDAGALNIGYVDEGPADGPAVILLHGWP
YDIHSFIDVVPMLTRSGYRVIVPYLRGYGSTRFRDAGAVRNGQPAALASDVVALMDALKIDKAILAGYDWGARSADIVAA
LWPQRVKGLVAVSGYLIGSQEAGKQPLPPKAELQWWYQFYFATERGRAGYDKNHRDFARLIWQTASPRWHFDDAVFERSA
AALDNPDHVAVTLYNYRWRLGLETGEAKYADWEARLATFPAIAVPTITMEGDANGAPHPEPAAYAKRFTGKYKHLLIRGG
VGHNLPQEAPRAFADAMIEVDHL
>Mature_343_residues
MKKTIDSKRRNLLAAIALSLAGAFALAETTNAAPDATAIAAQALPTFKTIRQIDAGALNIGYVDEGPADGPAVILLHGWP
YDIHSFIDVVPMLTRSGYRVIVPYLRGYGSTRFRDAGAVRNGQPAALASDVVALMDALKIDKAILAGYDWGARSADIVAA
LWPQRVKGLVAVSGYLIGSQEAGKQPLPPKAELQWWYQFYFATERGRAGYDKNHRDFARLIWQTASPRWHFDDAVFERSA
AALDNPDHVAVTLYNYRWRLGLETGEAKYADWEARLATFPAIAVPTITMEGDANGAPHPEPAAYAKRFTGKYKHLLIRGG
VGHNLPQEAPRAFADAMIEVDHL

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=145, Percent_Identity=28.9655172413793, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 37525; Mature: 37525

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIDSKRRNLLAAIALSLAGAFALAETTNAAPDATAIAAQALPTFKTIRQIDAGALNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
GYVDEGPADGPAVILLHGWPYDIHSFIDVVPMLTRSGYRVIVPYLRGYGSTRFRDAGAVR
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCCCC
NGQPAALASDVVALMDALKIDKAILAGYDWGARSADIVAALWPQRVKGLVAVSGYLIGSQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHEEEEEEEEEECH
EAGKQPLPPKAELQWWYQFYFATERGRAGYDKNHRDFARLIWQTASPRWHFDDAVFERSA
HCCCCCCCCCHHHEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
AALDNPDHVAVTLYNYRWRLGLETGEAKYADWEARLATFPAIAVPTITMEGDANGAPHPE
HHCCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEEEEECCCCCCCCCCC
PAAYAKRFTGKYKHLLIRGGVGHNLPQEAPRAFADAMIEVDHL
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKKTIDSKRRNLLAAIALSLAGAFALAETTNAAPDATAIAAQALPTFKTIRQIDAGALNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
GYVDEGPADGPAVILLHGWPYDIHSFIDVVPMLTRSGYRVIVPYLRGYGSTRFRDAGAVR
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCCCCC
NGQPAALASDVVALMDALKIDKAILAGYDWGARSADIVAALWPQRVKGLVAVSGYLIGSQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCHHHHHHEEEEEEEEEECH
EAGKQPLPPKAELQWWYQFYFATERGRAGYDKNHRDFARLIWQTASPRWHFDDAVFERSA
HCCCCCCCCCHHHEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
AALDNPDHVAVTLYNYRWRLGLETGEAKYADWEARLATFPAIAVPTITMEGDANGAPHPE
HHCCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHHHHHCCEEEEEEEEECCCCCCCCCCC
PAAYAKRFTGKYKHLLIRGGVGHNLPQEAPRAFADAMIEVDHL
HHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]