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The map label for this gene is irgA [H]

Identifier: 34496946

GI number: 34496946

Start: 1591785

End: 1593884

Strand: Reverse

Name: irgA [H]

Synonym: CV_1491

Alternate gene names: 34496946

Gene position: 1593884-1591785 (Counterclockwise)

Preceding gene: 34496949

Following gene: 34496945

Centisome position: 33.55

GC content: 61.29

Gene sequence:

>2100_bases
ATGAAAAACAAGCGCTCCCCGCACCTCGCGCGCCCGGCCTTCCGCCTGGCCATGCTGTCCGCCGCCGTCGGCGCCCTCTA
CCTGCCCGCCGCGCACGCCGCCGAAGCCGTGCTGCCCTCGGTGGTGGTGACCGCCACCGGCTACGAGCAGAAAATCAAGG
AAGCCCCGGCCAGCATTTCGGTGATCACCCGCGAAGAGCTGGAAAAGAAACCGTTCACCAACCTGGCCGACGCGATCCAG
GATCTGGAAGGCGTCAACATCAACGGCTCCGGCCCCGCCGACAAGGACATCTCCATCCGCGGCATGCCCGGCGAATACAC
ATTGATCTTGGTGGACGGCCGCCGCCAGAACACCCGCGAGGCCCGCAGCCGTGGCACCGGCGGTTTCCAGCAGTACCAGA
TCCCGCCGATGGAGGCGATCGAGCGCATCGAAGTGGTGCGCGGCCCGATGTCGTCGCTGTACGGCTCCGACGCGATGGGC
GGCGTGGTCAACATCATCACCCGCAAATCGCCCAAGGAATGGCACGGTTCGATGACGCTGGGCGGCACCATCACCGAGCA
CGCCGATGAAGGCAACACCGGCCAGAGCAGCTTCTGGGTCGGCGGCCCGCTGGTGAAAGACCTGCTGTCGCTGCAACTGT
ACGGCGCGCTGAACAATCAGGCGGAAGATAATATTTACTACGCCCGAAGCCGCGATGGCGGCAAAGATGCCGCCCATCTG
GGCGACTTCAACGCCAAGCTGAGCTTTACCCCGAACAAAGATCATGAGATCACCTTCGAGGCCGGCCACAATGAATTGCG
CAAAACCACGACGCCGGGCAAAACCCTCGCCCTCACATCCGACAAATATGATCAATTGGACCAGCGAGACCACTGGAGCC
TGAGCCACAACGGCAAGTACGGCATCGTGCGCTCGAATCTGGCGCTCTATCAGGAAATCGAAAAATCCAGTTCCGACACA
AACAATATCAACGACGGCACGGATCTGAAGATTACCAATACTACGCTGGATGGCCAGCTGTCCTTCCTGTTCGATCGCCA
CACGCTGAAGATCGGTACACAGGTCGGCCAACAAGTGGGTTCCAGCCTGCGAGCCCAGGAAGCGCTGAAACCGCCGTTCA
AATATGTCGGCACGCAGAACCCGGATAAGGTCACCGTAAATACCTGGGCACTGTTCGCCGAGGATACCTATGACCTTACC
GACAGCCTGAAATTGACTGGCGGTGGCCGCCTTGACCATCACAGCGTGTTCGGCAGCCACTTCACGCCGCGTCTGTACCT
GGTCGAGCAACTGAACTCGCAATGGACTTTGAAAGGCGGCGTCGGCAAGGGCTTCAAGGCCCCGACCATACGCCAGAGCA
CCGACGGTTACTGCATGCGCACCGGCAGCCAGGTGGAAACCGGCCTGCTGTGCGGCAATTCCAATCTGAAGCCGGAAGAA
AGCACCTCCTACGAGGCCAGCCTGCACTTCGACAACAACCAAGACCTGAGCGCCAACGCCACGCTGTTCTACAACGACTT
CAAGAACAAAGTGGTCAGCTACGGCACCGACCAGTTCACCAATCAGCTGATCGCAAAGGGCAAACCGGCGCGCGTCTATG
TTTACGGCAATGTCGACTCGGTGAACATCCGCGGCCTGGAGCTCTCCGGCAACTGGACGTTCGCGCCACGCTGGACCGTA
TCCGGCAACTACACCTACACCAAGTCCAAACGCCACGGCGGCAAGGAAACCAGCTACTCCGGCCAGTCGCTGGAAGGCAT
GCCGCTGGACAAGACGCCGGAGCACGCCGGCAACGTCAAGCTGGCCTGGAACCCGGTGGAGAAGCTTGACCTCTATACCC
GCCTGAACTTCGAAGGCAAGCAGTACTACACCGGCTTCCGCAACGGCGCCAACGTCGCCCGCACCCGCGGCGGCTCCAGC
ACCTGGGACCTGGGCGGCACTTACCGCATCAACAAGACCTTCGACGTCAATTTCGCTGTGTTCAACGTCGGCGACCGCAA
GGTGGCCATCGACGACCGCGCCCGCGATGGCGGCCTGGACGGCAACTGGATGGTCGACGAGGGCCGCCGCTATTGGCTGA
CCCTGACCGGCAAGTTCTAA

Upstream 100 bases:

>100_bases
ATCTAATCCGACGCCATGATCGGAACGGCTTGCGATGCGCCAGCCAGCTTGCCAATTGGATATGCGTTCCGTGATGAACA
CTCTGGGTATGACCAACACA

Downstream 100 bases:

>100_bases
ACCCCGCGCTCCCCGTCCGCTCCTCGAAAGCGGGTGGGAAGCCACGCACGGCAGTTGCCGGACCCCCTTGGTCCGCCAAC
TGCCTGTTCCCGTTTAAAAG

Product: outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MKNKRSPHLARPAFRLAMLSAAVGALYLPAAHAAEAVLPSVVVTATGYEQKIKEAPASISVITREELEKKPFTNLADAIQ
DLEGVNINGSGPADKDISIRGMPGEYTLILVDGRRQNTREARSRGTGGFQQYQIPPMEAIERIEVVRGPMSSLYGSDAMG
GVVNIITRKSPKEWHGSMTLGGTITEHADEGNTGQSSFWVGGPLVKDLLSLQLYGALNNQAEDNIYYARSRDGGKDAAHL
GDFNAKLSFTPNKDHEITFEAGHNELRKTTTPGKTLALTSDKYDQLDQRDHWSLSHNGKYGIVRSNLALYQEIEKSSSDT
NNINDGTDLKITNTTLDGQLSFLFDRHTLKIGTQVGQQVGSSLRAQEALKPPFKYVGTQNPDKVTVNTWALFAEDTYDLT
DSLKLTGGGRLDHHSVFGSHFTPRLYLVEQLNSQWTLKGGVGKGFKAPTIRQSTDGYCMRTGSQVETGLLCGNSNLKPEE
STSYEASLHFDNNQDLSANATLFYNDFKNKVVSYGTDQFTNQLIAKGKPARVYVYGNVDSVNIRGLELSGNWTFAPRWTV
SGNYTYTKSKRHGGKETSYSGQSLEGMPLDKTPEHAGNVKLAWNPVEKLDLYTRLNFEGKQYYTGFRNGANVARTRGGSS
TWDLGGTYRINKTFDVNFAVFNVGDRKVAIDDRARDGGLDGNWMVDEGRRYWLTLTGKF

Sequences:

>Translated_699_residues
MKNKRSPHLARPAFRLAMLSAAVGALYLPAAHAAEAVLPSVVVTATGYEQKIKEAPASISVITREELEKKPFTNLADAIQ
DLEGVNINGSGPADKDISIRGMPGEYTLILVDGRRQNTREARSRGTGGFQQYQIPPMEAIERIEVVRGPMSSLYGSDAMG
GVVNIITRKSPKEWHGSMTLGGTITEHADEGNTGQSSFWVGGPLVKDLLSLQLYGALNNQAEDNIYYARSRDGGKDAAHL
GDFNAKLSFTPNKDHEITFEAGHNELRKTTTPGKTLALTSDKYDQLDQRDHWSLSHNGKYGIVRSNLALYQEIEKSSSDT
NNINDGTDLKITNTTLDGQLSFLFDRHTLKIGTQVGQQVGSSLRAQEALKPPFKYVGTQNPDKVTVNTWALFAEDTYDLT
DSLKLTGGGRLDHHSVFGSHFTPRLYLVEQLNSQWTLKGGVGKGFKAPTIRQSTDGYCMRTGSQVETGLLCGNSNLKPEE
STSYEASLHFDNNQDLSANATLFYNDFKNKVVSYGTDQFTNQLIAKGKPARVYVYGNVDSVNIRGLELSGNWTFAPRWTV
SGNYTYTKSKRHGGKETSYSGQSLEGMPLDKTPEHAGNVKLAWNPVEKLDLYTRLNFEGKQYYTGFRNGANVARTRGGSS
TWDLGGTYRINKTFDVNFAVFNVGDRKVAIDDRARDGGLDGNWMVDEGRRYWLTLTGKF
>Mature_699_residues
MKNKRSPHLARPAFRLAMLSAAVGALYLPAAHAAEAVLPSVVVTATGYEQKIKEAPASISVITREELEKKPFTNLADAIQ
DLEGVNINGSGPADKDISIRGMPGEYTLILVDGRRQNTREARSRGTGGFQQYQIPPMEAIERIEVVRGPMSSLYGSDAMG
GVVNIITRKSPKEWHGSMTLGGTITEHADEGNTGQSSFWVGGPLVKDLLSLQLYGALNNQAEDNIYYARSRDGGKDAAHL
GDFNAKLSFTPNKDHEITFEAGHNELRKTTTPGKTLALTSDKYDQLDQRDHWSLSHNGKYGIVRSNLALYQEIEKSSSDT
NNINDGTDLKITNTTLDGQLSFLFDRHTLKIGTQVGQQVGSSLRAQEALKPPFKYVGTQNPDKVTVNTWALFAEDTYDLT
DSLKLTGGGRLDHHSVFGSHFTPRLYLVEQLNSQWTLKGGVGKGFKAPTIRQSTDGYCMRTGSQVETGLLCGNSNLKPEE
STSYEASLHFDNNQDLSANATLFYNDFKNKVVSYGTDQFTNQLIAKGKPARVYVYGNVDSVNIRGLELSGNWTFAPRWTV
SGNYTYTKSKRHGGKETSYSGQSLEGMPLDKTPEHAGNVKLAWNPVEKLDLYTRLNFEGKQYYTGFRNGANVARTRGGSS
TWDLGGTYRINKTFDVNFAVFNVGDRKVAIDDRARDGGLDGNWMVDEGRRYWLTLTGKF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=716, Percent_Identity=32.6815642458101, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI1786798, Length=647, Percent_Identity=30.1391035548686, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1790405, Length=142, Percent_Identity=37.3239436619718, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77091; Mature: 77091

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKRSPHLARPAFRLAMLSAAVGALYLPAAHAAEAVLPSVVVTATGYEQKIKEAPASIS
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEECCHHHHHHHCCCCEE
VITREELEKKPFTNLADAIQDLEGVNINGSGPADKDISIRGMPGEYTLILVDGRRQNTRE
EEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHH
ARSRGTGGFQQYQIPPMEAIERIEVVRGPMSSLYGSDAMGGVVNIITRKSPKEWHGSMTL
HHHCCCCCCCEECCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCCHHHCCCEEE
GGTITEHADEGNTGQSSFWVGGPLVKDLLSLQLYGALNNQAEDNIYYARSRDGGKDAAHL
CCEEECCCCCCCCCCCCEEECCHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCCCHHC
GDFNAKLSFTPNKDHEITFEAGHNELRKTTTPGKTLALTSDKYDQLDQRDHWSLSHNGKY
CCCCCEEEECCCCCCEEEEECCCCHHHHCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCE
GIVRSNLALYQEIEKSSSDTNNINDGTDLKITNTTLDGQLSFLFDRHTLKIGTQVGQQVG
EEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEEECEEEEHHHHHHHHHH
SSLRAQEALKPPFKYVGTQNPDKVTVNTWALFAEDTYDLTDSLKLTGGGRLDHHSVFGSH
HHHHHHHHHCCCHHHCCCCCCCEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCC
FTPRLYLVEQLNSQWTLKGGVGKGFKAPTIRQSTDGYCMRTGSQVETGLLCGNSNLKPEE
CCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCC
STSYEASLHFDNNQDLSANATLFYNDFKNKVVSYGTDQFTNQLIAKGKPARVYVYGNVDS
CCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCE
VNIRGLELSGNWTFAPRWTVSGNYTYTKSKRHGGKETSYSGQSLEGMPLDKTPEHAGNVK
EEEEEEEECCCEEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LAWNPVEKLDLYTRLNFEGKQYYTGFRNGANVARTRGGSSTWDLGGTYRINKTFDVNFAV
EEECCHHHEEEEEEECCCCCEEECCCCCCCCCEECCCCCCEECCCCEEEEEEEEEEEEEE
FNVGDRKVAIDDRARDGGLDGNWMVDEGRRYWLTLTGKF
EECCCEEEEECCCCCCCCCCCCEEEECCCEEEEEEECCC
>Mature Secondary Structure
MKNKRSPHLARPAFRLAMLSAAVGALYLPAAHAAEAVLPSVVVTATGYEQKIKEAPASIS
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEECCHHHHHHHCCCCEE
VITREELEKKPFTNLADAIQDLEGVNINGSGPADKDISIRGMPGEYTLILVDGRRQNTRE
EEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCHHH
ARSRGTGGFQQYQIPPMEAIERIEVVRGPMSSLYGSDAMGGVVNIITRKSPKEWHGSMTL
HHHCCCCCCCEECCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCCHHHCCCEEE
GGTITEHADEGNTGQSSFWVGGPLVKDLLSLQLYGALNNQAEDNIYYARSRDGGKDAAHL
CCEEECCCCCCCCCCCCEEECCHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCCCHHC
GDFNAKLSFTPNKDHEITFEAGHNELRKTTTPGKTLALTSDKYDQLDQRDHWSLSHNGKY
CCCCCEEEECCCCCCEEEEECCCCHHHHCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCE
GIVRSNLALYQEIEKSSSDTNNINDGTDLKITNTTLDGQLSFLFDRHTLKIGTQVGQQVG
EEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEEECEEEEHHHHHHHHHH
SSLRAQEALKPPFKYVGTQNPDKVTVNTWALFAEDTYDLTDSLKLTGGGRLDHHSVFGSH
HHHHHHHHHCCCHHHCCCCCCCEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCC
FTPRLYLVEQLNSQWTLKGGVGKGFKAPTIRQSTDGYCMRTGSQVETGLLCGNSNLKPEE
CCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCC
STSYEASLHFDNNQDLSANATLFYNDFKNKVVSYGTDQFTNQLIAKGKPARVYVYGNVDS
CCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCE
VNIRGLELSGNWTFAPRWTVSGNYTYTKSKRHGGKETSYSGQSLEGMPLDKTPEHAGNVK
EEEEEEEECCCEEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LAWNPVEKLDLYTRLNFEGKQYYTGFRNGANVARTRGGSSTWDLGGTYRINKTFDVNFAV
EEECCHHHEEEEEEECCCCCEEECCCCCCCCCEECCCCCCEECCCCEEEEEEEEEEEEEE
FNVGDRKVAIDDRARDGGLDGNWMVDEGRRYWLTLTGKF
EECCCEEEEECCCCCCCCCCCCEEEECCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]