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The map label for this gene is entF [H]

Identifier: 34496941

GI number: 34496941

Start: 1584375

End: 1587617

Strand: Reverse

Name: entF [H]

Synonym: CV_1486

Alternate gene names: 34496941

Gene position: 1587617-1584375 (Counterclockwise)

Preceding gene: 34496942

Following gene: 34496940

Centisome position: 33.42

GC content: 73.91

Gene sequence:

>3243_bases
GTGCGCAAGGCCAGCCGGCTGCTGGCCCAGGGCCAGATCGACGCCTGGCAGCGCGCGGCCCAGGCCTGCGGCGTCAACTG
GGCGGCCTGGACCGCGGCGGCGGTATCGGCCTGGCTGGCGCGGCACTGCGGGCAGCGCGCGATCACGCTGGGCCTGCCGG
TGATGAACCGCATGGGCTCGGCCGCGCTCGGCGTGCCCTGCATGGCGATGAACATCGCGCCGCTCAGCCTGCGGCTGGAT
CCGGCCAGCAGCCTGGGAGAACTCGCGCGCCAGGCCGCCGACGGCCTGCGCGGCATCCGCCCCCACCAGCGCTACCGCTA
CGAATGGCTGCGCGGCGACCTGGGCCGGCTGGATGGCCGCCAGCGGCTGTTCGGCCCGGTGCTCAACCTGATGCCCTTCG
ACCGCCACGCGCCGTTCGACGGGCTGGAAAGCCGCATCCGCCCGGTCAGCTCCGGCCCGGTGGAAGACCTGTCCATCAAC
ATCAACCTGCTCAACACCGAGTGGCGGCTGAGCCTGGAAGCCCATCCGGACGCCTATCCGGCCGAGCGGCTGGACGCGCT
GTGGCGCGATCTGCCGCAGTGGCTGGACGCGCTGGCCCAGGCCGAGCCGGACACGCCGCTGGCGCGATTGCTGCCTGAAT
TGCCCCCGCTGTCCATCCTCGCAGGCCCGGCGCTGGAGCAGCCCGCCATCCCGGTGATGGAACGGCTGGCCGCGCTGGCC
GGTTCCCAGCCCGACGCGGCCGCGCTGGAAGGCGAAGGACTGTCCCTCAGCTACCGCCAGCTGCTGGAACGGGCGCGCGC
CCTGGCCGGCCGGCTGAAAGCCCATGGCCTGGAGGACGGCGACCGCGTCGCCATCCTGCTGCCGCGCTCGGTGGACGCCA
TTGTCGCCATCCTGGGCACCTTGTGGGCCGGCGGCTGCTACGTCCCGCTCGATCCGCAGGGCCCGGCCGCCCGCCTGGCC
ATGGTGCTGGACGACGCCCGCCCCAGGCTGGCGCTGACCCGCCGCCGCTGGGCCGAGCTATGCGGCGAGCTGCCGGCGCT
GTGCCTGGACGAAGCCCCGGCCGACGACGCGCCGCGGCTGGAGCGCTGCGCGGCCGGCATCGACAGCCCGGCCTACCTGC
TCTACACCTCCGGCTCCACCGGCAAGCCCAACGGCGTGCTGGTCGGCCACCGCGCGCTGGCGCATTTCGTCTCCAGCGCC
GGCCAGCTCTACCGCGTCCGGACCGGCGAGCGCATCCTGCAGTTCGCGCCGCTGCACTTCGACGCCAGCATCGAGGAAAT
CTTCCTGGCGCTGTGCCATGGCGGCACGCTGGCGCTGCGCGACGACGCGATGCTGGAATCCATGCCGGCCTTCGCCGACG
CCGTGGCGCGGCTGCGGATAGACGTGCTGGACCTGCCCACCGCCTTCTGGCACGAGTTGGCCTACGCGCTGACGCCGGAG
CTGGCCGCCCGGCTGTCCCGCGTCCGCCTCGCCATCATCGGCGGCGAAGCCGCGCTGCCCGAGCGCGCGCGCCGCTGGCG
CGAACTGCTGCCAACCGCCACGCTGCTCAACAGCTACGGCCCCACCGAGGCCTCCATCATCGCCACCGGCGCCGCGCTGG
CGGGGCCGGACGCGGTGTGGGACGGCAACGAGGACATCCCCATCGGCCTGCCCCGCCCCGGCGTGGACGCCGCCATCGTC
GACGCCGGCCTGCGGCCGGTGGCGCAGGGCGAGGAAGGCGAGCTGTGCCTGCTGGGCGACGCGCTGGCCATCGGCTACCT
GGGCCGCGACGAACTGACCGCCCGCCGCTTCGTGACGTTGGACGCGCTGCCCGGCGCGCCGCGCGCCTACCGCACCGGCG
ACCGCGCGGTCTGGCGCGGCGGCCAGTTGCGCTTCCTCGGCCGGCTGGACCAGGAGCTGAAGATCAGCGGCCTGCGCATC
GACCCGGCCGAAGTGGAAAACGCGCTGCTCGCCTGCCCCGGCGTGCGCGAAGCCGCCGTGATCGGCCTGCCGCTGGCCGG
CGGCGGCTACGCGCTGGCAGCCTTCCTCGCCGCCGACGCGGAACCGGACGCCGGCGCGCTGCGCCGCCAACTGGCCGAAC
GGCTGCCCGCCGCCGCCATTCCCGACCGCTGGCAATGGCTGGAGCAGCTGCCGCGCAACGTCAACGGCAAGATAGACCGC
AAGCAGCTGGCCGCCCTGGGCGACGCGCCAGGCCAAGGCGCGTCCCAGGCCGCCGAGGCGACGCCGCTGGAGCGGCAGAT
CATGGAAGTGTGGAGCCAGGCGCTGGGCCGCATGCCGGAAGGGCCGCACGCCAACTTCTTCGCCATGGGCGGCAAGTCGC
TGCAAGCGATCCAGGCCGCCAACCGGCTGGCCCAGCGGCTGCAGCGCGAAATCGCCGTATCGGCGCTGTTCAGCTACAAC
ACCGTATCCGCGCTGGCGCAAGCCTTGAACGCGCCAGCCGCCCACCGCCCGCCCGCGGCGAGCCAGGGCGGCGAGTTCGC
GCCGCTGCTGACCATCCAGCCGGGCGCGCTGCCGGCGCTGTTCTGCCTGCACCCGGCGGAAGGCCTGTCCTGGTGCTACC
TGGGGCTGGCGCGCCACCTGCCGGACACCGCGATCTACGGCCTGCAGGCCACCGGCATCCAGGGCGAGCCGCCCGTCAGC
TTCGACGCGATGGTGGCCGACTACGTCGCCCGCGTCCGCGCCATCCAGCCGCAGGGCCCGTACCGGCTGCTGGGCTGGTC
GCTGGGCGGCGCGCTGGCGCAGGCGATGGCCGCCGCGCTCGCCGACGCCGGCGAGCCGGTGGAGCTGGTGGCATTGATGG
ACAGCTACCCGGTCAGCAGCTGGCATGGCCGGCCCGAGCCTACGCTGCACGACGCGCTGGTGACGGTGCTCAGCGTCAAC
GGCGAAGTGGACGCCGACGCCGACGGCCTGCCGCTGGACAACGACGCCATCTACCAGCGACTGCTGCGCCCCGGCAGCCC
GCTGGCGCCGCTGGGCCGGGAGGCGCTGGAAAAGCTGGGCCAGGCCTCGCTGCACGGCATGCGCCTGTTCCGCGGCAGCC
GCACGCCGGTCTACCGGGGCGACATGCTGCTGTTCCGCGCCGGCCGCCATCCCGAAGACGCCCCGACGCCGGCCGACTGG
CAGCCCTATCTGCAGGGCCGGCTGGACTGCGTGGAGCTGGATTGCGACCACTTCGGCATGAGCGATCCGGAGCCGATGCG
CCGCATAGGCGAAGAGCTGTCCAGACGTCTGCGCAGAACGTGA

Upstream 100 bases:

>100_bases
GTCGGAACAGCGCGGGCGGGACCAGGCCTTCTGGACCGCGCGGCAGCAAGCCTTCCCCGCCGCCGCCACGCTGGCGCCGC
CGCAGCCGCTGGCCAATGGC

Downstream 100 bases:

>100_bases
CATGGCTTTATCGGGCGCGCATGGCTTGCGCGCCCGATAAAGCACATGATTCCCATCATTGTCATTTAATAAATAATTAC
AACCCTACAAATAGCTATTC

Product: enterobactin synthetase component F

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1080; Mature: 1080

Protein sequence:

>1080_residues
MRKASRLLAQGQIDAWQRAAQACGVNWAAWTAAAVSAWLARHCGQRAITLGLPVMNRMGSAALGVPCMAMNIAPLSLRLD
PASSLGELARQAADGLRGIRPHQRYRYEWLRGDLGRLDGRQRLFGPVLNLMPFDRHAPFDGLESRIRPVSSGPVEDLSIN
INLLNTEWRLSLEAHPDAYPAERLDALWRDLPQWLDALAQAEPDTPLARLLPELPPLSILAGPALEQPAIPVMERLAALA
GSQPDAAALEGEGLSLSYRQLLERARALAGRLKAHGLEDGDRVAILLPRSVDAIVAILGTLWAGGCYVPLDPQGPAARLA
MVLDDARPRLALTRRRWAELCGELPALCLDEAPADDAPRLERCAAGIDSPAYLLYTSGSTGKPNGVLVGHRALAHFVSSA
GQLYRVRTGERILQFAPLHFDASIEEIFLALCHGGTLALRDDAMLESMPAFADAVARLRIDVLDLPTAFWHELAYALTPE
LAARLSRVRLAIIGGEAALPERARRWRELLPTATLLNSYGPTEASIIATGAALAGPDAVWDGNEDIPIGLPRPGVDAAIV
DAGLRPVAQGEEGELCLLGDALAIGYLGRDELTARRFVTLDALPGAPRAYRTGDRAVWRGGQLRFLGRLDQELKISGLRI
DPAEVENALLACPGVREAAVIGLPLAGGGYALAAFLAADAEPDAGALRRQLAERLPAAAIPDRWQWLEQLPRNVNGKIDR
KQLAALGDAPGQGASQAAEATPLERQIMEVWSQALGRMPEGPHANFFAMGGKSLQAIQAANRLAQRLQREIAVSALFSYN
TVSALAQALNAPAAHRPPAASQGGEFAPLLTIQPGALPALFCLHPAEGLSWCYLGLARHLPDTAIYGLQATGIQGEPPVS
FDAMVADYVARVRAIQPQGPYRLLGWSLGGALAQAMAAALADAGEPVELVALMDSYPVSSWHGRPEPTLHDALVTVLSVN
GEVDADADGLPLDNDAIYQRLLRPGSPLAPLGREALEKLGQASLHGMRLFRGSRTPVYRGDMLLFRAGRHPEDAPTPADW
QPYLQGRLDCVELDCDHFGMSDPEPMRRIGEELSRRLRRT

Sequences:

>Translated_1080_residues
MRKASRLLAQGQIDAWQRAAQACGVNWAAWTAAAVSAWLARHCGQRAITLGLPVMNRMGSAALGVPCMAMNIAPLSLRLD
PASSLGELARQAADGLRGIRPHQRYRYEWLRGDLGRLDGRQRLFGPVLNLMPFDRHAPFDGLESRIRPVSSGPVEDLSIN
INLLNTEWRLSLEAHPDAYPAERLDALWRDLPQWLDALAQAEPDTPLARLLPELPPLSILAGPALEQPAIPVMERLAALA
GSQPDAAALEGEGLSLSYRQLLERARALAGRLKAHGLEDGDRVAILLPRSVDAIVAILGTLWAGGCYVPLDPQGPAARLA
MVLDDARPRLALTRRRWAELCGELPALCLDEAPADDAPRLERCAAGIDSPAYLLYTSGSTGKPNGVLVGHRALAHFVSSA
GQLYRVRTGERILQFAPLHFDASIEEIFLALCHGGTLALRDDAMLESMPAFADAVARLRIDVLDLPTAFWHELAYALTPE
LAARLSRVRLAIIGGEAALPERARRWRELLPTATLLNSYGPTEASIIATGAALAGPDAVWDGNEDIPIGLPRPGVDAAIV
DAGLRPVAQGEEGELCLLGDALAIGYLGRDELTARRFVTLDALPGAPRAYRTGDRAVWRGGQLRFLGRLDQELKISGLRI
DPAEVENALLACPGVREAAVIGLPLAGGGYALAAFLAADAEPDAGALRRQLAERLPAAAIPDRWQWLEQLPRNVNGKIDR
KQLAALGDAPGQGASQAAEATPLERQIMEVWSQALGRMPEGPHANFFAMGGKSLQAIQAANRLAQRLQREIAVSALFSYN
TVSALAQALNAPAAHRPPAASQGGEFAPLLTIQPGALPALFCLHPAEGLSWCYLGLARHLPDTAIYGLQATGIQGEPPVS
FDAMVADYVARVRAIQPQGPYRLLGWSLGGALAQAMAAALADAGEPVELVALMDSYPVSSWHGRPEPTLHDALVTVLSVN
GEVDADADGLPLDNDAIYQRLLRPGSPLAPLGREALEKLGQASLHGMRLFRGSRTPVYRGDMLLFRAGRHPEDAPTPADW
QPYLQGRLDCVELDCDHFGMSDPEPMRRIGEELSRRLRRT
>Mature_1080_residues
MRKASRLLAQGQIDAWQRAAQACGVNWAAWTAAAVSAWLARHCGQRAITLGLPVMNRMGSAALGVPCMAMNIAPLSLRLD
PASSLGELARQAADGLRGIRPHQRYRYEWLRGDLGRLDGRQRLFGPVLNLMPFDRHAPFDGLESRIRPVSSGPVEDLSIN
INLLNTEWRLSLEAHPDAYPAERLDALWRDLPQWLDALAQAEPDTPLARLLPELPPLSILAGPALEQPAIPVMERLAALA
GSQPDAAALEGEGLSLSYRQLLERARALAGRLKAHGLEDGDRVAILLPRSVDAIVAILGTLWAGGCYVPLDPQGPAARLA
MVLDDARPRLALTRRRWAELCGELPALCLDEAPADDAPRLERCAAGIDSPAYLLYTSGSTGKPNGVLVGHRALAHFVSSA
GQLYRVRTGERILQFAPLHFDASIEEIFLALCHGGTLALRDDAMLESMPAFADAVARLRIDVLDLPTAFWHELAYALTPE
LAARLSRVRLAIIGGEAALPERARRWRELLPTATLLNSYGPTEASIIATGAALAGPDAVWDGNEDIPIGLPRPGVDAAIV
DAGLRPVAQGEEGELCLLGDALAIGYLGRDELTARRFVTLDALPGAPRAYRTGDRAVWRGGQLRFLGRLDQELKISGLRI
DPAEVENALLACPGVREAAVIGLPLAGGGYALAAFLAADAEPDAGALRRQLAERLPAAAIPDRWQWLEQLPRNVNGKIDR
KQLAALGDAPGQGASQAAEATPLERQIMEVWSQALGRMPEGPHANFFAMGGKSLQAIQAANRLAQRLQREIAVSALFSYN
TVSALAQALNAPAAHRPPAASQGGEFAPLLTIQPGALPALFCLHPAEGLSWCYLGLARHLPDTAIYGLQATGIQGEPPVS
FDAMVADYVARVRAIQPQGPYRLLGWSLGGALAQAMAAALADAGEPVELVALMDSYPVSSWHGRPEPTLHDALVTVLSVN
GEVDADADGLPLDNDAIYQRLLRPGSPLAPLGREALEKLGQASLHGMRLFRGSRTPVYRGDMLLFRAGRHPEDAPTPADW
QPYLQGRLDCVELDCDHFGMSDPEPMRRIGEELSRRLRRT

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI28416953, Length=577, Percent_Identity=26.1698440207972, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI187761345, Length=548, Percent_Identity=27.5547445255474, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI187761343, Length=548, Percent_Identity=27.5547445255474, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI45580730, Length=455, Percent_Identity=25.4945054945055, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI38505220, Length=515, Percent_Identity=24.4660194174757, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI115511026, Length=524, Percent_Identity=22.9007633587786, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI42544132, Length=529, Percent_Identity=21.9281663516068, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI122937307, Length=514, Percent_Identity=23.7354085603113, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI156151445, Length=565, Percent_Identity=23.8938053097345, Blast_Score=85, Evalue=4e-16,
Organism=Escherichia coli, GI1786801, Length=1103, Percent_Identity=31.3689936536718, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1788107, Length=564, Percent_Identity=24.468085106383, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI145693145, Length=520, Percent_Identity=25.1923076923077, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1790505, Length=576, Percent_Identity=25.3472222222222, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1786810, Length=538, Percent_Identity=23.4200743494424, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550940, Length=575, Percent_Identity=24.3478260869565, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17556356, Length=652, Percent_Identity=22.239263803681, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17557194, Length=533, Percent_Identity=22.7016885553471, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538037, Length=531, Percent_Identity=22.5988700564972, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17558820, Length=512, Percent_Identity=24.21875, Blast_Score=100, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17559526, Length=536, Percent_Identity=23.8805970149254, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560140, Length=513, Percent_Identity=21.2475633528265, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17531443, Length=547, Percent_Identity=20.8409506398537, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32563687, Length=482, Percent_Identity=22.6141078838174, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=370, Percent_Identity=25.4054054054054, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=654, Percent_Identity=23.394495412844, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24648676, Length=631, Percent_Identity=28.6846275752773, Blast_Score=152, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24581924, Length=526, Percent_Identity=25.6653992395437, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24648260, Length=520, Percent_Identity=23.0769230769231, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18859661, Length=520, Percent_Identity=23.6538461538462, Blast_Score=81, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356947, Length=512, Percent_Identity=21.875, Blast_Score=81, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922652, Length=514, Percent_Identity=23.3463035019455, Blast_Score=76, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 116169; Mature: 116169

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKASRLLAQGQIDAWQRAAQACGVNWAAWTAAAVSAWLARHCGQRAITLGLPVMNRMGS
CCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCC
AALGVPCMAMNIAPLSLRLDPASSLGELARQAADGLRGIRPHQRYRYEWLRGDLGRLDGR
HHHCCCCCEEEECEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCH
QRLFGPVLNLMPFDRHAPFDGLESRIRPVSSGPVEDLSININLLNTEWRLSLEAHPDAYP
HHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCEEEEEEECCCCCCC
AERLDALWRDLPQWLDALAQAEPDTPLARLLPELPPLSILAGPALEQPAIPVMERLAALA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHCCCCCCCCCCHHHHHHHHHHH
GSQPDAAALEGEGLSLSYRQLLERARALAGRLKAHGLEDGDRVAILLPRSVDAIVAILGT
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LWAGGCYVPLDPQGPAARLAMVLDDARPRLALTRRRWAELCGELPALCLDEAPADDAPRL
HHCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHH
ERCAAGIDSPAYLLYTSGSTGKPNGVLVGHRALAHFVSSAGQLYRVRTGERILQFAPLHF
HHHHCCCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCC
DASIEEIFLALCHGGTLALRDDAMLESMPAFADAVARLRIDVLDLPTAFWHELAYALTPE
CCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHH
LAARLSRVRLAIIGGEAALPERARRWRELLPTATLLNSYGPTEASIIATGAALAGPDAVW
HHHHHHHEEEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEECCCHHCCCCCCC
DGNEDIPIGLPRPGVDAAIVDAGLRPVAQGEEGELCLLGDALAIGYLGRDELTARRFVTL
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHCCCCCHHHHHHHEEEE
DALPGAPRAYRTGDRAVWRGGQLRFLGRLDQELKISGLRIDPAEVENALLACPGVREAAV
ECCCCCCCCCCCCCHHHCCCCCEEEHHHCCCCCEECCCCCCHHHHHHHHEECCCCCCCEE
IGLPLAGGGYALAAFLAADAEPDAGALRRQLAERLPAAAIPDRWQWLEQLPRNVNGKIDR
EEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCH
KQLAALGDAPGQGASQAAEATPLERQIMEVWSQALGRMPEGPHANFFAMGGKSLQAIQAA
HHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHH
NRLAQRLQREIAVSALFSYNTVSALAQALNAPAAHRPPAASQGGEFAPLLTIQPGALPAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCHH
FCLHPAEGLSWCYLGLARHLPDTAIYGLQATGIQGEPPVSFDAMVADYVARVRAIQPQGP
HEECCCCCHHHHHHHHHHHCCCHHEECEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
YRLLGWSLGGALAQAMAAALADAGEPVELVALMDSYPVSSWHGRPEPTLHDALVTVLSVN
EEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCHHHHHHHHHHCCC
GEVDADADGLPLDNDAIYQRLLRPGSPLAPLGREALEKLGQASLHGMRLFRGSRTPVYRG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEC
DMLLFRAGRHPEDAPTPADWQPYLQGRLDCVELDCDHFGMSDPEPMRRIGEELSRRLRRT
CEEEEECCCCCCCCCCCCCCCHHHCCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKASRLLAQGQIDAWQRAAQACGVNWAAWTAAAVSAWLARHCGQRAITLGLPVMNRMGS
CCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCC
AALGVPCMAMNIAPLSLRLDPASSLGELARQAADGLRGIRPHQRYRYEWLRGDLGRLDGR
HHHCCCCCEEEECEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCCH
QRLFGPVLNLMPFDRHAPFDGLESRIRPVSSGPVEDLSININLLNTEWRLSLEAHPDAYP
HHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCEEEEEEECCCCCCC
AERLDALWRDLPQWLDALAQAEPDTPLARLLPELPPLSILAGPALEQPAIPVMERLAALA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHCCCCCCCCCCHHHHHHHHHHH
GSQPDAAALEGEGLSLSYRQLLERARALAGRLKAHGLEDGDRVAILLPRSVDAIVAILGT
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHH
LWAGGCYVPLDPQGPAARLAMVLDDARPRLALTRRRWAELCGELPALCLDEAPADDAPRL
HHCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHH
ERCAAGIDSPAYLLYTSGSTGKPNGVLVGHRALAHFVSSAGQLYRVRTGERILQFAPLHF
HHHHCCCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCC
DASIEEIFLALCHGGTLALRDDAMLESMPAFADAVARLRIDVLDLPTAFWHELAYALTPE
CCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHH
LAARLSRVRLAIIGGEAALPERARRWRELLPTATLLNSYGPTEASIIATGAALAGPDAVW
HHHHHHHEEEEEECCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCEEECCCHHCCCCCCC
DGNEDIPIGLPRPGVDAAIVDAGLRPVAQGEEGELCLLGDALAIGYLGRDELTARRFVTL
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHCCCCCHHHHHHHEEEE
DALPGAPRAYRTGDRAVWRGGQLRFLGRLDQELKISGLRIDPAEVENALLACPGVREAAV
ECCCCCCCCCCCCCHHHCCCCCEEEHHHCCCCCEECCCCCCHHHHHHHHEECCCCCCCEE
IGLPLAGGGYALAAFLAADAEPDAGALRRQLAERLPAAAIPDRWQWLEQLPRNVNGKIDR
EEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCH
KQLAALGDAPGQGASQAAEATPLERQIMEVWSQALGRMPEGPHANFFAMGGKSLQAIQAA
HHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHH
NRLAQRLQREIAVSALFSYNTVSALAQALNAPAAHRPPAASQGGEFAPLLTIQPGALPAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCHH
FCLHPAEGLSWCYLGLARHLPDTAIYGLQATGIQGEPPVSFDAMVADYVARVRAIQPQGP
HEECCCCCHHHHHHHHHHHCCCHHEECEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
YRLLGWSLGGALAQAMAAALADAGEPVELVALMDSYPVSSWHGRPEPTLHDALVTVLSVN
EEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCCCCCHHHHHHHHHHCCC
GEVDADADGLPLDNDAIYQRLLRPGSPLAPLGREALEKLGQASLHGMRLFRGSRTPVYRG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEC
DMLLFRAGRHPEDAPTPADWQPYLQGRLDCVELDCDHFGMSDPEPMRRIGEELSRRLRRT
CEEEEECCCCCCCCCCCCCCCHHHCCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]