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The map label for this gene is entC [H]

Identifier: 34496940

GI number: 34496940

Start: 1582984

End: 1584162

Strand: Reverse

Name: entC [H]

Synonym: CV_1485

Alternate gene names: 34496940

Gene position: 1584162-1582984 (Counterclockwise)

Preceding gene: 34496941

Following gene: 34496939

Centisome position: 33.34

GC content: 70.4

Gene sequence:

>1179_bases
ATGCACACCGCGTCGGCCCTGACCGGCAACGCCGAAGACGGCGAGTTTTATTTCATGTCGTCCCACCGCAGCCTGAAGGC
CGGCGGTGTCCATTCCCGGATCCGCACGCCCGCCCGCGGCGCGCTGGATCCCCGCAGCGCTTTTAGCCTCGAAGTGGCGG
AAGCCTTCGCCCGCGCCCGCGCCGGCGGCATCGAATCCCCAGTGCTGATGGGCGCCATCCCCTTCGACATCGACCAGCCT
TCCGAATTGTTCATCCCCGCCCGCCATGCCTTCTTCGACCGCGGCGAGCGCCTGCTGGCGGCCGCCCAGCGCGCCGGCGA
CGGCGGCAAGGTGGTCAGCGCGCGCAGCATTCCGGACGAGCAAGGCTTCAAGGCGGCGGTCAGCCAGGCCATCGAGCAAT
TCGGCCGCGGCGAGATCCGCAAGGCGGTGCTGTCCCGCGTGCTGGAGGTGGACTTCGAGCGCCCGGTGTCGGCGGAACGG
GTGTTCGACGCGGTATGCGCGCAGAATCCCAACGGCTACCAGTTCCAGCTGCCGCTGGCCGACGGCGGCCACCTGGTGGG
CGTGAGTCCGGAGCTGCTGCTGCAAAAGGACGGCGCGCGCGTGCGCACCTTCCCGCTGGCCGGCTCCGCCAAGCGCCAGG
GCGACCCGGCGGCTGACGCCGCCGCCAGCGCCAAGCTGCTGGATTCGGCGAAGGACCACTACGAGCACAGCCTGGTGATA
GACGATATCCGCGACGTGCTGGCGCCCTATTGCTCCCGGCTGGACATCCCCGCCGCGCCGACGCTGCTGGCCACCCGCGC
GATGTGGCATCTGGGCTCGCCGATAGACGGCGTGCTCTCCGACCCCTCGCTGCCGATTCTGCAGCTGGCCTGCCGCCTGC
ATCCGACGCCGGCGATCTGCGGCTTCCCCACCCAGGCTTCGCGCCAACTGATCCGAGAGATCGAGCCGTTCGAGCGCGGC
GTGTTCAGCGGCATCGTCGGCTGGTGCGACGAACACGGCAACGGCGAATGGGCGGTGACCATACGCTGCGCCACCGTCGC
CCAGCGCCGCGTGCGGCTGTTCGCCGGCGCCGGCATCGTCGCCGCTTCCACGCCGGAAGCGGAATGGGCGGAAACCCAGG
CCAAGCTCGGCACCATGCTGGGTGCCTTCGGCCTGTCCGGCCAGGAGGCGGTGGCATGA

Upstream 100 bases:

>100_bases
ATATTTCCCGAGCATGAACAGGGGCATTCAACAATTGACAGGTGATGGCTTTGAATATACATTGAACGATAATTATTATC
ATTATCATCGGAGCGCAATC

Downstream 100 bases:

>100_bases
GCGTCGCCTTCACCCGCTGGCCGGATGACCTGGCCGCGCGCTACCGCGCCGCCGGCTACTGGAACGACCAGCCGATGACC
GAGATGCTGGCGCGGCAATG

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MHTASALTGNAEDGEFYFMSSHRSLKAGGVHSRIRTPARGALDPRSAFSLEVAEAFARARAGGIESPVLMGAIPFDIDQP
SELFIPARHAFFDRGERLLAAAQRAGDGGKVVSARSIPDEQGFKAAVSQAIEQFGRGEIRKAVLSRVLEVDFERPVSAER
VFDAVCAQNPNGYQFQLPLADGGHLVGVSPELLLQKDGARVRTFPLAGSAKRQGDPAADAAASAKLLDSAKDHYEHSLVI
DDIRDVLAPYCSRLDIPAAPTLLATRAMWHLGSPIDGVLSDPSLPILQLACRLHPTPAICGFPTQASRQLIREIEPFERG
VFSGIVGWCDEHGNGEWAVTIRCATVAQRRVRLFAGAGIVAASTPEAEWAETQAKLGTMLGAFGLSGQEAVA

Sequences:

>Translated_392_residues
MHTASALTGNAEDGEFYFMSSHRSLKAGGVHSRIRTPARGALDPRSAFSLEVAEAFARARAGGIESPVLMGAIPFDIDQP
SELFIPARHAFFDRGERLLAAAQRAGDGGKVVSARSIPDEQGFKAAVSQAIEQFGRGEIRKAVLSRVLEVDFERPVSAER
VFDAVCAQNPNGYQFQLPLADGGHLVGVSPELLLQKDGARVRTFPLAGSAKRQGDPAADAAASAKLLDSAKDHYEHSLVI
DDIRDVLAPYCSRLDIPAAPTLLATRAMWHLGSPIDGVLSDPSLPILQLACRLHPTPAICGFPTQASRQLIREIEPFERG
VFSGIVGWCDEHGNGEWAVTIRCATVAQRRVRLFAGAGIVAASTPEAEWAETQAKLGTMLGAFGLSGQEAVA
>Mature_392_residues
MHTASALTGNAEDGEFYFMSSHRSLKAGGVHSRIRTPARGALDPRSAFSLEVAEAFARARAGGIESPVLMGAIPFDIDQP
SELFIPARHAFFDRGERLLAAAQRAGDGGKVVSARSIPDEQGFKAAVSQAIEQFGRGEIRKAVLSRVLEVDFERPVSAER
VFDAVCAQNPNGYQFQLPLADGGHLVGVSPELLLQKDGARVRTFPLAGSAKRQGDPAADAAASAKLLDSAKDHYEHSLVI
DDIRDVLAPYCSRLDIPAAPTLLATRAMWHLGSPIDGVLSDPSLPILQLACRLHPTPAICGFPTQASRQLIREIEPFERG
VFSGIVGWCDEHGNGEWAVTIRCATVAQRRVRLFAGAGIVAASTPEAEWAETQAKLGTMLGAFGLSGQEAVA

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=374, Percent_Identity=46.7914438502674, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI87082077, Length=260, Percent_Identity=31.9230769230769, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788114, Length=202, Percent_Identity=30.1980198019802, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787518, Length=291, Percent_Identity=27.4914089347079, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=265, Percent_Identity=29.0566037735849, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 41824; Mature: 41824

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTASALTGNAEDGEFYFMSSHRSLKAGGVHSRIRTPARGALDPRSAFSLEVAEAFARAR
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
AGGIESPVLMGAIPFDIDQPSELFIPARHAFFDRGERLLAAAQRAGDGGKVVSARSIPDE
CCCCCCCEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
QGFKAAVSQAIEQFGRGEIRKAVLSRVLEVDFERPVSAERVFDAVCAQNPNGYQFQLPLA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEEC
DGGHLVGVSPELLLQKDGARVRTFPLAGSAKRQGDPAADAAASAKLLDSAKDHYEHSLVI
CCCEEEECCHHHHEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DDIRDVLAPYCSRLDIPAAPTLLATRAMWHLGSPIDGVLSDPSLPILQLACRLHPTPAIC
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
GFPTQASRQLIREIEPFERGVFSGIVGWCDEHGNGEWAVTIRCATVAQRRVRLFAGAGIV
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCEE
AASTPEAEWAETQAKLGTMLGAFGLSGQEAVA
EECCCCHHHHHHHHHHHHHHHHCCCCCHHHCC
>Mature Secondary Structure
MHTASALTGNAEDGEFYFMSSHRSLKAGGVHSRIRTPARGALDPRSAFSLEVAEAFARAR
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
AGGIESPVLMGAIPFDIDQPSELFIPARHAFFDRGERLLAAAQRAGDGGKVVSARSIPDE
CCCCCCCEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
QGFKAAVSQAIEQFGRGEIRKAVLSRVLEVDFERPVSAERVFDAVCAQNPNGYQFQLPLA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEEC
DGGHLVGVSPELLLQKDGARVRTFPLAGSAKRQGDPAADAAASAKLLDSAKDHYEHSLVI
CCCEEEECCHHHHEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DDIRDVLAPYCSRLDIPAAPTLLATRAMWHLGSPIDGVLSDPSLPILQLACRLHPTPAIC
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
GFPTQASRQLIREIEPFERGVFSGIVGWCDEHGNGEWAVTIRCATVAQRRVRLFAGAGIV
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCEE
AASTPEAEWAETQAKLGTMLGAFGLSGQEAVA
EECCCCHHHHHHHHHHHHHHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]