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The map label for this gene is 34496841

Identifier: 34496841

GI number: 34496841

Start: 1463897

End: 1465375

Strand: Direct

Name: 34496841

Synonym: CV_1386

Alternate gene names: NA

Gene position: 1463897-1465375 (Clockwise)

Preceding gene: 34496840

Following gene: 34496842

Centisome position: 30.81

GC content: 68.02

Gene sequence:

>1479_bases
ATGGCTGAGCCCGGGGTGTTCCTGATCCATGGATTGGGCGGCACCCAGTACGATCTGGGCTCCATGCACAAACGTCTGAA
AAACGCGGGCTTCGTCACCCATGCGCTGACGCTGCCGGGCCACGGCACGCGGCCGGAGGATCTGGCCGGCGTCAGGATGG
AAGACTGGCTGGACGCGGCGCGCGCCAAGTACCGCGAGATCGTCGGCCAGCACGAGGTGCTGCACGTGATGGGCATGTGC
ATGGGCGCTCTGTTGGCGCTGGAACTGGTCAAGCTCGAGCGCCATGACAAGGGCCGGCTGGTGGCGCTGGCGCCGCCGGT
GTACATAGACGGCTGGGCCACGCCCTGGTACCGGGGCCTGCGCCCCTTGCTATACCGGGTGCCGGGTTTGCCCGAGCGGA
TGAAGGTGGAGGAAGAGGAGCCTTACGGCATCAAGAACGAGCAGCTGCGCGCCATCGTCAAGGCCAAGTTCGAGCGTGGC
GAGAATTTCCACTATGGCTGGGTGCCATTGGCCTGCATCCGCGAAGTGGACCGGCTGCGCGCGGCGGTGATGCGCGGGCT
GGACAGGATCGCCTGCCCCACCCTGGTGGTGCATGCGCGCGAGGACGAGCTGACCAGCCTGCGCTCCGCGCACTTTCTGG
TTGAGCGCATCGGCAGCGGCAAGCGCGCCGGCCTGGCGCGCATGGTGGTGCTGGAAGACAGCTATCACATGGTGTGCGTG
GACAACGACAGGGAAATCGTCGGCAAGCACGTGCTGGAGTTTTTCAACGCCAACGTCGCAGGCGGTTTCGGCATGGGCAT
GGTCGATCCGGCGATGGCGCCGGCGGAAATGGCGGCGCTGCTGGCCGCGGCGCGGCGCGCGCTGGAGCAGGGCGACTTCG
CCGCCCTGTACCGGCTGGGGATACCGGATTTCGTCTGGCTGCAGCCGGGCCGCAACCGCAGCAGCGGCGCGTTTCCGGGA
CGCAAGGGGCTGCGGCGGCTGCAGGGCTGGGCGGGTGAGGGAGCGAGCTTCGCCGCTTTCGGCGCCGCCGTGATCAACGC
CGGCATGGCGGTGCAGCCCGCCACGCTGCTGCATCGCGGCCTGGCTTCCCCAGGCGTGCTGGCGCTGCAGCTGCGCAGGG
GCAAGCTGCTGGAGGCCCGATGGTTTCCGGACGATCTGGACGCCGAGGATGCCCACTTCGGCGGCGAGCCGCTGCCGGAC
GGACCCAGCGAGCAGGAAAAGGCTTTCGAAGCCGCCGCCGCGTTGTCGCGCACGTTGCGCAAGGCGCCGGACAACGCCAC
GCTGCTGAACTTGTACGCCTTGTACAAGCAAGGGGCGATGGGCGATGCCACAGGCGAGCGTCCAAGCGTGATGGACATGG
TGGGGCGCGCCAAGCACGATGCCTGGATGGCCAGGCGAGGCATGAGCCGGGAGCAGGCGATGGCGGATTACGTGGCCTTG
GTGAATCGGCTGAAAGCCGAGGAGAGCCTGGAGGCGTGA

Upstream 100 bases:

>100_bases
CCCTTGCGGGTGCGGGAGCGGCTGGCTTGCGTGCGCGGCGCGGACGATTCGGTGGAAATGGTGGTGGGCATGTTGCGGCC
GGAGCCTCTGGAGAGCGGCG

Downstream 100 bases:

>100_bases
GCGCCATCGATGGCCGGCGCACGGGTTGGCGGCCTTGGAGTGGCTAACAAAATTCCTGATGCGGCGTTGCGCCGACTTGT
CGTACTCAAGTACTGCCTGC

Product: esterase

Products: NA

Alternate protein names: Carboxylesterase; Esterase/Lipase; Alpha/Beta Hydrolase Fold; Esterase; Esterase/Lipase-Like Protein; Alpha/Beta Hydrolase; Acylglycerol Lipase; Thermostable Monoacylglycerol Lipase; PGAP1 Family Protein; Esterase/Lipase-Like; Monoacylglycerol Lipase; Alpha/Beta Hydrolase Domain-Containing Protein; Phospholipase/Carboxylesterase; Esterase/Lipase/Thioesterase Protein; Lipase; Alpha/Beta Hydrolase Fold-Containing Protein

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MAEPGVFLIHGLGGTQYDLGSMHKRLKNAGFVTHALTLPGHGTRPEDLAGVRMEDWLDAARAKYREIVGQHEVLHVMGMC
MGALLALELVKLERHDKGRLVALAPPVYIDGWATPWYRGLRPLLYRVPGLPERMKVEEEEPYGIKNEQLRAIVKAKFERG
ENFHYGWVPLACIREVDRLRAAVMRGLDRIACPTLVVHAREDELTSLRSAHFLVERIGSGKRAGLARMVVLEDSYHMVCV
DNDREIVGKHVLEFFNANVAGGFGMGMVDPAMAPAEMAALLAAARRALEQGDFAALYRLGIPDFVWLQPGRNRSSGAFPG
RKGLRRLQGWAGEGASFAAFGAAVINAGMAVQPATLLHRGLASPGVLALQLRRGKLLEARWFPDDLDAEDAHFGGEPLPD
GPSEQEKAFEAAAALSRTLRKAPDNATLLNLYALYKQGAMGDATGERPSVMDMVGRAKHDAWMARRGMSREQAMADYVAL
VNRLKAEESLEA

Sequences:

>Translated_492_residues
MAEPGVFLIHGLGGTQYDLGSMHKRLKNAGFVTHALTLPGHGTRPEDLAGVRMEDWLDAARAKYREIVGQHEVLHVMGMC
MGALLALELVKLERHDKGRLVALAPPVYIDGWATPWYRGLRPLLYRVPGLPERMKVEEEEPYGIKNEQLRAIVKAKFERG
ENFHYGWVPLACIREVDRLRAAVMRGLDRIACPTLVVHAREDELTSLRSAHFLVERIGSGKRAGLARMVVLEDSYHMVCV
DNDREIVGKHVLEFFNANVAGGFGMGMVDPAMAPAEMAALLAAARRALEQGDFAALYRLGIPDFVWLQPGRNRSSGAFPG
RKGLRRLQGWAGEGASFAAFGAAVINAGMAVQPATLLHRGLASPGVLALQLRRGKLLEARWFPDDLDAEDAHFGGEPLPD
GPSEQEKAFEAAAALSRTLRKAPDNATLLNLYALYKQGAMGDATGERPSVMDMVGRAKHDAWMARRGMSREQAMADYVAL
VNRLKAEESLEA
>Mature_491_residues
AEPGVFLIHGLGGTQYDLGSMHKRLKNAGFVTHALTLPGHGTRPEDLAGVRMEDWLDAARAKYREIVGQHEVLHVMGMCM
GALLALELVKLERHDKGRLVALAPPVYIDGWATPWYRGLRPLLYRVPGLPERMKVEEEEPYGIKNEQLRAIVKAKFERGE
NFHYGWVPLACIREVDRLRAAVMRGLDRIACPTLVVHAREDELTSLRSAHFLVERIGSGKRAGLARMVVLEDSYHMVCVD
NDREIVGKHVLEFFNANVAGGFGMGMVDPAMAPAEMAALLAAARRALEQGDFAALYRLGIPDFVWLQPGRNRSSGAFPGR
KGLRRLQGWAGEGASFAAFGAAVINAGMAVQPATLLHRGLASPGVLALQLRRGKLLEARWFPDDLDAEDAHFGGEPLPDG
PSEQEKAFEAAAALSRTLRKAPDNATLLNLYALYKQGAMGDATGERPSVMDMVGRAKHDAWMARRGMSREQAMADYVALV
NRLKAEESLEA

Specific function: Unknown

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI120433590, Length=82, Percent_Identity=40.2439024390244, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI120433593, Length=79, Percent_Identity=41.7721518987342, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=81, Percent_Identity=46.9135802469136, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506027, Length=80, Percent_Identity=45, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321474, Length=81, Percent_Identity=41.9753086419753, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24659809, Length=85, Percent_Identity=40, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24659814, Length=85, Percent_Identity=40, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54039; Mature: 53908

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPGVFLIHGLGGTQYDLGSMHKRLKNAGFVTHALTLPGHGTRPEDLAGVRMEDWLDAA
CCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCCHHHHHHHH
RAKYREIVGQHEVLHVMGMCMGALLALELVKLERHDKGRLVALAPPVYIDGWATPWYRGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEECCCCCHHHHHH
RPLLYRVPGLPERMKVEEEEPYGIKNEQLRAIVKAKFERGENFHYGWVPLACIREVDRLR
HHHHHHCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
AAVMRGLDRIACPTLVVHAREDELTSLRSAHFLVERIGSGKRAGLARMVVLEDSYHMVCV
HHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEEE
DNDREIVGKHVLEFFNANVAGGFGMGMVDPAMAPAEMAALLAAARRALEQGDFAALYRLG
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCC
IPDFVWLQPGRNRSSGAFPGRKGLRRLQGWAGEGASFAAFGAAVINAGMAVQPATLLHRG
CCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHC
LASPGVLALQLRRGKLLEARWFPDDLDAEDAHFGGEPLPDGPSEQEKAFEAAAALSRTLR
CCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KAPDNATLLNLYALYKQGAMGDATGERPSVMDMVGRAKHDAWMARRGMSREQAMADYVAL
HCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VNRLKAEESLEA
HHHHHHHHHCCC
>Mature Secondary Structure 
AEPGVFLIHGLGGTQYDLGSMHKRLKNAGFVTHALTLPGHGTRPEDLAGVRMEDWLDAA
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCCHHHHHHHH
RAKYREIVGQHEVLHVMGMCMGALLALELVKLERHDKGRLVALAPPVYIDGWATPWYRGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEECCCCCHHHHHH
RPLLYRVPGLPERMKVEEEEPYGIKNEQLRAIVKAKFERGENFHYGWVPLACIREVDRLR
HHHHHHCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
AAVMRGLDRIACPTLVVHAREDELTSLRSAHFLVERIGSGKRAGLARMVVLEDSYHMVCV
HHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEEEEE
DNDREIVGKHVLEFFNANVAGGFGMGMVDPAMAPAEMAALLAAARRALEQGDFAALYRLG
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCC
IPDFVWLQPGRNRSSGAFPGRKGLRRLQGWAGEGASFAAFGAAVINAGMAVQPATLLHRG
CCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHC
LASPGVLALQLRRGKLLEARWFPDDLDAEDAHFGGEPLPDGPSEQEKAFEAAAALSRTLR
CCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KAPDNATLLNLYALYKQGAMGDATGERPSVMDMVGRAKHDAWMARRGMSREQAMADYVAL
HCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VNRLKAEESLEA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA