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The map label for this gene is ihfA

Identifier: 34496809

GI number: 34496809

Start: 1427104

End: 1427406

Strand: Direct

Name: ihfA

Synonym: CV_1354

Alternate gene names: 34496809

Gene position: 1427104-1427406 (Clockwise)

Preceding gene: 34496808

Following gene: 34496810

Centisome position: 30.04

GC content: 55.45

Gene sequence:

>303_bases
ATGACTTTGACGAAGGCTGAACTGGCCGATTTGCTGTTTGACCAGGTTGGTCTGAACAAACGCGAAGCCAAGGACATGGT
CGAGTCGTTTTTCGAAGAGATCCGGCTGGCGCTGGAGTCCGGGGATTCGGTTAAGCTGTCCGGTTTCGGCAACTTCCAGT
TGCGCGACAAGCCGCAGCGTCCGGGCCGCAATCCCAAGACCGGGGAAGAGATTCCCATTACCGCGCGTCGTGTGGTAACG
TTCCACGCAAGCCAGAAACTCAAGGGAATGGTTGAGCAATACCATGCTAACAAGCAAGGCTGA

Upstream 100 bases:

>100_bases
CGGAACTGGGCGCGCAGCTGCGCGTGTGATCGAGATGTGGGCGGGCGGATTCGAACGGGTCCGCCCGTCGATTGTGGTTC
AGAAGTTTGAGGGGAATGTC

Downstream 100 bases:

>100_bases
TCTGCCGTCGATTCCGTCCAAGCGTTACTTCACCATCAGCGAAGTCGGCGAACTCGCTGGGGTGAAGCCCCATGTGCTGC
GCTATTGGGAGCAGGAATTC

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 100; Mature: 99

Protein sequence:

>100_residues
MTLTKAELADLLFDQVGLNKREAKDMVESFFEEIRLALESGDSVKLSGFGNFQLRDKPQRPGRNPKTGEEIPITARRVVT
FHASQKLKGMVEQYHANKQG

Sequences:

>Translated_100_residues
MTLTKAELADLLFDQVGLNKREAKDMVESFFEEIRLALESGDSVKLSGFGNFQLRDKPQRPGRNPKTGEEIPITARRVVT
FHASQKLKGMVEQYHANKQG
>Mature_99_residues
TLTKAELADLLFDQVGLNKREAKDMVESFFEEIRLALESGDSVKLSGFGNFQLRDKPQRPGRNPKTGEEIPITARRVVTF
HASQKLKGMVEQYHANKQG

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=73.9130434782609, Blast_Score=140, Evalue=1e-35,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=38.8888888888889, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=34.8314606741573, Blast_Score=64, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_CHRVO (Q7NYC0)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901024.1
- HSSP:   P0A6X7
- ProteinModelPortal:   Q7NYC0
- SMR:   Q7NYC0
- GeneID:   2551275
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1354
- NMPDR:   fig|243365.1.peg.1354
- HOGENOM:   HBG705085
- OMA:   VRGETVK
- PhylomeDB:   Q7NYC0
- ProtClustDB:   PRK00285
- BioCyc:   CVIO243365:CV_1354-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11291; Mature: 11160

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTKAELADLLFDQVGLNKREAKDMVESFFEEIRLALESGDSVKLSGFGNFQLRDKPQR
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCC
PGRNPKTGEEIPITARRVVTFHASQKLKGMVEQYHANKQG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLTKAELADLLFDQVGLNKREAKDMVESFFEEIRLALESGDSVKLSGFGNFQLRDKPQR
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCC
PGRNPKTGEEIPITARRVVTFHASQKLKGMVEQYHANKQG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782